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Evidence‐based medicine and health economics: a case study of end stage renal disease

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  • Luke Vale
  • Cam Donaldson
  • Conal Daly
  • Marion Campbell
  • June Cody
  • Adrian Grant
  • Izhar Khan
  • Paul Lawrence
  • Shiela Wallace
  • Alison Macleod

Abstract

This paper explores the potential for use of an economic evaluation framework alongside systematic reviews. Clinical issues in dialysis therapy for end stage renal disease are used as case studies. The effectiveness data required were obtained from a systematic review of randomized controlled trials. Resource use and cost data were obtained from three sources; the identified randomized controlled trials, a separate review of observational studies and primary data collection. The results of the case studies show that, although simple economic evaluations were possible, issues arose, such as how transferable results are between settings and how appropriate it is to focus on the average patient. The interface between economic evaluation and systematic reviews needs to be further developed in order to ensure that the best available evidence can be used to inform future policy and research. Copyright © 2000 John Wiley & Sons, Ltd.

Suggested Citation

  • Luke Vale & Cam Donaldson & Conal Daly & Marion Campbell & June Cody & Adrian Grant & Izhar Khan & Paul Lawrence & Shiela Wallace & Alison Macleod, 2000. "Evidence‐based medicine and health economics: a case study of end stage renal disease," Health Economics, John Wiley & Sons, Ltd., vol. 9(4), pages 337-351, June.
    • Handle: RePEc:wly:hlthec:v:9:y:2000:i:4:p:337-351
    DOI: 10.1002/1099-1050(200006)9:4<337::AID-HEC518>3.0.CO;2-O
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    1. Karen Gerard & Gavin Mooney, 1993. "Qaly league tables: Handle with care," Health Economics, John Wiley & Sons, Ltd., vol. 2(1), pages 59-64, April.
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