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Exploring the clinical translation intensity of papers published by the world’s top scientists in basic medicine

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  • Dongyu Zang

    (China Medical University)

  • Chunli Liu

    (China Medical University
    China Medical University)

Abstract

The extent to which basic medical research is translated into clinical practice is a topic of interest to all stakeholders. In this study, we assessed the clinical translation intensity of papers published by scientists who have made outstanding contributions to the field of basic medicine (Lasker Prize winners for Basic Medical Research). Approximate Potential for Translation (APT), Translational science scores (TS), and Citations by clinical research (Cited by Clin.) were analyzed as dependent variables. A traditional citation indicator was used as a reference (relative citation ratio, RCR). In order to examine the correlation between these different indicators and the characteristics of the paper, the author, and the institution. we used nonparametric tests, Spearman correlations, ordinal least squares regressions (OLS), quantile regressions, and zero-inflated negative binomial regression methods. We found that among the basic medical research papers published by Lasker Basic Medicine Award winners, (1) 20% are cited by clinical research; 11.6% of the papers were more valuable for clinical research than basic research; 12.8% have a probability of more than 50% to be cited in future clinical studies; (2) Spearman correlations were conducted among APT, TS, Cited by Clin., RCR, and all of the other continuous variables. There is a significant, positive, low to moderate correlation between APT, TS, and Cited by Clin (APT and TS: r = 0.549, p

Suggested Citation

  • Dongyu Zang & Chunli Liu, 2023. "Exploring the clinical translation intensity of papers published by the world’s top scientists in basic medicine," Scientometrics, Springer;Akadémiai Kiadó, vol. 128(4), pages 2371-2416, April.
    • Handle: RePEc:spr:scient:v:128:y:2023:i:4:d:10.1007_s11192-023-04634-4
    DOI: 10.1007/s11192-023-04634-4
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