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Cost-effectiveness of two online interventions supporting self-care for eczema for parents/carers and young people

Author

Listed:
  • Tracey H. Sach

    (University of East Anglia
    University of Southampton)

  • Mary Onoja

    (University of East Anglia)

  • Holly Clarke

    (University of East Anglia)

  • Miriam Santer

    (University of Southampton)

  • Ingrid Muller

    (University of Southampton)

  • Taeko Becque

    (University of Southampton)

  • Beth Stuart

    (University of Southampton
    Wolfson Institute of Population Health, Queen Mary University of London)

  • Julie Hooper

    (University of Southampton)

  • Mary Steele

    (University of Southampton)

  • Sylvia Wilczynska

    (King’s Clinical Trial Unit, King’s College London, Institute of Psychiatry, Psychology and Neuroscience)

  • Matthew J. Ridd

    (Population Health Sciences, Bristol Medical School, University of Bristol)

  • Amanda Roberts

    (University of Nottingham)

  • Amina Ahmed

    (University of Nottingham)

  • Lucy Yardley

    (University of Southampton)

  • Paul Little

    (University of Southampton)

  • Kate Greenwell

    (University of Southampton
    University of Southampton
    University of Bristol)

  • Katy Sivyer

    (University of Southampton
    University of Bristol)

  • Jacqui Nuttall

    (University of Southampton and University Hospital Southampton NHS Foundation Trust)

  • Gareth Griffiths

    (University of Southampton and University Hospital Southampton NHS Foundation Trust)

  • Sandra Lawton

    (The Rotherham NHS Foundation Trust)

  • Sinéad M. Langan

    (London School of Hygiene and Tropical Medicine)

  • Laura Howells

    (University of Nottingham, Applied Health Services Research Building (Building Number 42), University Park)

  • Paul Leighton

    (University of Nottingham, Applied Health Services Research Building (Building Number 42), University Park)

  • Hywel C. Williams

    (University of Nottingham, Applied Health Services Research Building (Building Number 42), University Park)

  • Kim S. Thomas

    (University of Nottingham, Applied Health Services Research Building (Building Number 42), University Park)

Abstract

Objective To estimate the cost-effectiveness of online behavioral interventions (EczemaCareOnline.org.uk) designed to support eczema self-care management for parents/carers and young people from an NHS perspective. Methods Two within-trial economic evaluations, using regression-based approaches, adjusting for baseline and pre-specified confounder variables, were undertaken alongside two independent, pragmatic, parallel group, unmasked randomized controlled trials, recruiting through primary care. Trial 1 recruited 340 parents/carers of children aged 0–12 years and Trial 2 337 young people aged 13–25 years with eczema scored ≥ 5 on Patient-Oriented Eczema Measure (POEM). Participants were randomized (1:1) to online intervention plus usual care or usual care alone. Resource use, collected via medical notes review, was valued using published unit costs in UK £Sterling 2021. Quality-of-life was elicited using proxy CHU-9D in Trial 1 and self-report EQ-5D-5L in Trial 2. Results The intervention was dominant (cost saving and more effective) with a high probability of cost-effectiveness (> 68%) in most analyses. The exception was the complete case cost–utility analysis for Trial 1 (omitting participants with children aged

Suggested Citation

  • Tracey H. Sach & Mary Onoja & Holly Clarke & Miriam Santer & Ingrid Muller & Taeko Becque & Beth Stuart & Julie Hooper & Mary Steele & Sylvia Wilczynska & Matthew J. Ridd & Amanda Roberts & Amina Ahme, 2024. "Cost-effectiveness of two online interventions supporting self-care for eczema for parents/carers and young people," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 25(7), pages 1165-1176, September.
  • Handle: RePEc:spr:eujhec:v:25:y:2024:i:7:d:10.1007_s10198-023-01649-9
    DOI: 10.1007/s10198-023-01649-9
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    References listed on IDEAS

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    1. Andrew R. Willan & Andrew H. Briggs & Jeffrey S. Hoch, 2004. "Regression methods for covariate adjustment and subgroup analysis for non‐censored cost‐effectiveness data," Health Economics, John Wiley & Sons, Ltd., vol. 13(5), pages 461-475, May.
    2. Rita Faria & Manuel Gomes & David Epstein & Ian White, 2014. "A Guide to Handling Missing Data in Cost-Effectiveness Analysis Conducted Within Randomised Controlled Trials," PharmacoEconomics, Springer, vol. 32(12), pages 1157-1170, December.
    3. Katherine Stevens, 2012. "Valuation of the Child Health Utility 9D Index," PharmacoEconomics, Springer, vol. 30(8), pages 729-747, August.
    4. Kamilla Koszorú & Krisztina Hajdu & Valentin Brodszky & Alex Bató & L. Hunor Gergely & Anikó Kovács & Zsuzsanna Beretzky & Miklós Sárdy & Andrea Szegedi & Fanni Rencz, 2023. "Comparing the psychometric properties of the EQ-5D-3L and EQ-5D-5L descriptive systems and utilities in atopic dermatitis," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 24(1), pages 139-152, February.
    Full references (including those not matched with items on IDEAS)

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    More about this item

    Keywords

    Economic evaluation; Cost-effectiveness; Atopic eczema; Atopic dermatitis; Online interventions;
    All these keywords.

    JEL classification:

    • D61 - Microeconomics - - Welfare Economics - - - Allocative Efficiency; Cost-Benefit Analysis
    • I10 - Health, Education, and Welfare - - Health - - - General

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