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Large-scale whole exome sequencing studies identify two genes,CTSL and APOE, associated with lung cancer

Author

Listed:
  • Jingxiong Xu
  • Wei Xu
  • Jiyeon Choi
  • Yonathan Brhane
  • David C Christiani
  • Jui Kothari
  • James McKay
  • John K Field
  • Michael P A Davies
  • Geoffrey Liu
  • Christopher I Amos
  • Rayjean J Hung
  • Laurent Briollais

Abstract

Common genetic variants associated with lung cancer have been well studied in the past decade. However, only 12.3% heritability has been explained by these variants. In this study, we investigate the contribution of rare variants (RVs) (minor allele frequency

Suggested Citation

  • Jingxiong Xu & Wei Xu & Jiyeon Choi & Yonathan Brhane & David C Christiani & Jui Kothari & James McKay & John K Field & Michael P A Davies & Geoffrey Liu & Christopher I Amos & Rayjean J Hung & Lauren, 2023. "Large-scale whole exome sequencing studies identify two genes,CTSL and APOE, associated with lung cancer," PLOS Genetics, Public Library of Science, vol. 19(9), pages 1-13, September.
    • Handle: RePEc:plo:pgen00:1010902
    DOI: 10.1371/journal.pgen.1010902
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    1. Mattson, M.E. & Pollack, E.S. & Cullen, J.W., 1987. "What are the odds that smoking will kill you?," American Journal of Public Health, American Public Health Association, vol. 77(4), pages 425-431.
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