Modular deregulation of central carbon metabolism for efficient xylose utilization in Saccharomyces cerevisiae
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DOI: 10.1038/s41467-025-59966-x
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- Quanli Liu & Tao Yu & Xiaowei Li & Yu Chen & Kate Campbell & Jens Nielsen & Yun Chen, 2019. "Rewiring carbon metabolism in yeast for high level production of aromatic chemicals," Nature Communications, Nature, vol. 10(1), pages 1-13, December.
- Wei Kang & Tian Ma & Min Liu & Jiale Qu & Zhenjun Liu & Huawei Zhang & Bin Shi & Shuai Fu & Juncai Ma & Louis Tung Faat Lai & Sicong He & Jianan Qu & Shannon Wing-Ngor Au & Byung Ho Kang & Wilson Chun, 2019. "Modular enzyme assembly for enhanced cascade biocatalysis and metabolic flux," Nature Communications, Nature, vol. 10(1), pages 1-11, December.
- Yongjin J. Zhou & Nicolaas A. Buijs & Zhiwei Zhu & Jiufu Qin & Verena Siewers & Jens Nielsen, 2016. "Production of fatty acid-derived oleochemicals and biofuels by synthetic yeast cell factories," Nature Communications, Nature, vol. 7(1), pages 1-9, September.
- Edward M. Rubin, 2008. "Genomics of cellulosic biofuels," Nature, Nature, vol. 454(7206), pages 841-845, August.
- Thomas L. Ruegg & Eun-Mi Kim & Blake A. Simmons & Jay D. Keasling & Steven W. Singer & Taek Soon Lee & Michael P. Thelen, 2014. "An auto-inducible mechanism for ionic liquid resistance in microbial biofuel production," Nature Communications, Nature, vol. 5(1), pages 1-7, May.
- Adam L. Meadows & Kristy M. Hawkins & Yoseph Tsegaye & Eugene Antipov & Youngnyun Kim & Lauren Raetz & Robert H. Dahl & Anna Tai & Tina Mahatdejkul-Meadows & Lan Xu & Lishan Zhao & Madhukar S. Dasika , 2016. "Rewriting yeast central carbon metabolism for industrial isoprenoid production," Nature, Nature, vol. 537(7622), pages 694-697, September.
- Hongzhong Lu & Feiran Li & Benjamín J. Sánchez & Zhengming Zhu & Gang Li & Iván Domenzain & Simonas Marcišauskas & Petre Mihail Anton & Dimitra Lappa & Christian Lieven & Moritz Emanuel Beber & Nikola, 2019. "A consensus S. cerevisiae metabolic model Yeast8 and its ecosystem for comprehensively probing cellular metabolism," Nature Communications, Nature, vol. 10(1), pages 1-13, December.
- Jiufu Qin & Yongjin J. Zhou & Anastasia Krivoruchko & Mingtao Huang & Lifang Liu & Sakda Khoomrung & Verena Siewers & Bo Jiang & Jens Nielsen, 2015. "Modular pathway rewiring of Saccharomyces cerevisiae enables high-level production of L-ornithine," Nature Communications, Nature, vol. 6(1), pages 1-11, November.
- Venkatesh Endalur Gopinarayanan & Nikhil U. Nair, 2018. "A semi-synthetic regulon enables rapid growth of yeast on xylose," Nature Communications, Nature, vol. 9(1), pages 1-12, December.
- Zongjie Dai & Mingtao Huang & Yun Chen & Verena Siewers & Jens Nielsen, 2018. "Global rewiring of cellular metabolism renders Saccharomyces cerevisiae Crabtree negative," Nature Communications, Nature, vol. 9(1), pages 1-8, December.
- Mingtao Huang & Jichen Bao & Björn M. Hallström & Dina Petranovic & Jens Nielsen, 2017. "Efficient protein production by yeast requires global tuning of metabolism," Nature Communications, Nature, vol. 8(1), pages 1-12, December.
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