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Global, Parameterwise and Joint Shrinkage Factor Estimation

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  • Dunkler, Daniela
  • Sauerbrei, Willi
  • Heinze, Georg

Abstract

The predictive value of a statistical model can often be improved by applying shrinkage methods. This can be achieved, e.g., by regularized regression or empirical Bayes approaches. Various types of shrinkage factors can also be estimated after a maximum likelihood fit has been obtained: while global shrinkage modifies all regression coefficients by the same factor, parameterwise shrinkage factors differ between regression coefficients. The latter ones have been proposed especially in the context of variable selection. With variables which are either highly correlated or associated with regard to contents, such as dummy variables coding a categorical variable, or several parameters describing a nonlinear effect, parameterwise shrinkage factors may not be the best choice. For such cases, we extend the present methodology by so-called 'joint shrinkage factors', a compromise between global and parameterwise shrinkage. Shrinkage factors are often estimated using leave-one-out resampling. We also discuss a computationally simple and much faster approximation to resampling-based shrinkage factor estimation, can be easily obtained in most standard software packages for regression analyses. This alternative may be relevant for simulation studies and other computerintensive investigations. Furthermore, we provide an R package shrink implementing the mentioned shrinkage methods for models fitted by linear, generalized linear, or Cox regression, even if these models involve fractional polynomials or restricted cubic splines to estimate the influence of a continuous variable by a nonlinear function. The approaches and usage of the package shrink are illustrated by means of two examples.

Suggested Citation

  • Dunkler, Daniela & Sauerbrei, Willi & Heinze, Georg, 2016. "Global, Parameterwise and Joint Shrinkage Factor Estimation," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 69(i08).
  • Handle: RePEc:jss:jstsof:v:069:i08
    DOI: http://hdl.handle.net/10.18637/jss.v069.i08
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    References listed on IDEAS

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    1. Sauerbrei, W. & Meier-Hirmer, C. & Benner, A. & Royston, P., 2006. "Multivariable regression model building by using fractional polynomials: Description of SAS, STATA and R programs," Computational Statistics & Data Analysis, Elsevier, vol. 50(12), pages 3464-3485, August.
    2. J. C. Van Houwelingen, 2001. "Shrinkage and Penalized Likelihood as Methods to Improve Predictive Accuracy," Statistica Neerlandica, Netherlands Society for Statistics and Operations Research, vol. 55(1), pages 17-34, March.
    3. Friedman, Jerome H. & Hastie, Trevor & Tibshirani, Rob, 2010. "Regularization Paths for Generalized Linear Models via Coordinate Descent," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 33(i01).
    4. Willi Sauerbrei, 1999. "The Use of Resampling Methods to Simplify Regression Models in Medical Statistics," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 48(3), pages 313-329.
    5. E. W. Steyerberg & M. J. C. Eijkemans & J. D. F. Habbema, 2001. "Application of Shrinkage Techniques in Logistic Regression Analysis: A Case Study," Statistica Neerlandica, Netherlands Society for Statistics and Operations Research, vol. 55(1), pages 76-88, March.
    6. W. Sauerbrei & P. Royston, 1999. "Building multivariable prognostic and diagnostic models: transformation of the predictors by using fractional polynomials," Journal of the Royal Statistical Society Series A, Royal Statistical Society, vol. 162(1), pages 71-94.
    7. Patrick Royston & Douglas G. Altman, 1994. "Regression Using Fractional Polynomials of Continuous Covariates: Parsimonious Parametric Modelling," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 43(3), pages 429-453, September.
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    Cited by:

    1. Bhaumik, Dulal K. & Nordgren, Rachel K., 2019. "Prediction and calibration for multiple correlated variables," Journal of Multivariate Analysis, Elsevier, vol. 173(C), pages 313-327.

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