IDEAS home Printed from https://ideas.repec.org/a/gam/jmathe/v13y2025i9p1480-d1646634.html
   My bibliography  Save this article

Enhancing Recognition and Categorization of Skin Lesions with Tailored Deep Convolutional Networks and Robust Data Augmentation Techniques

Author

Listed:
  • Syed Ibrar Hussain

    (Dipartimento di Matematica e Informatica, Università degli Studi di Palermo, Via Archirafi 34, 90123 Palermo, Italy
    The authors contributed equally to this work.)

  • Elena Toscano

    (Dipartimento di Matematica e Informatica, Università degli Studi di Palermo, Via Archirafi 34, 90123 Palermo, Italy
    The authors contributed equally to this work.)

Abstract

This study introduces deep convolutional neural network-based methods for the detection and classification of skin lesions, enhancing system accuracy through a combination of architectures, pre-processing techniques and data augmentation. Multiple networks, including XceptionNet, DenseNet, MobileNet, NASNet Mobile, and EfficientNet, were evaluated to test deep learning’s potential in complex, multi-class classification tasks. Training these models on pre-processed datasets with optimized hyper-parameters (e.g., batch size, learning rate, and dropout) improved classification precision for early-stage skin cancers. Evaluation measures such as accuracy and loss confirmed high classification efficiency with minimal overfitting, as the validation results aligned closely with training. DenseNet-201 and MobileNet-V3 Large demonstrated strong generalization abilities, whereas EfficientNetV2-B3 and NASNet Mobile achieved the best balance between accuracy and efficiency. The application of different augmentation rates per class also enhanced the handling of imbalanced data, resulting in more accurate large-scale detection. Comprehensive pre-processing ensured balanced class representation, and EfficientNetV2 models achieved exceptional classification accuracy, attributed to their optimized architecture balancing depth, width, and resolution. These models showed high convergence rates and generalization, supporting their suitability for medical imaging tasks using transfer learning.

Suggested Citation

  • Syed Ibrar Hussain & Elena Toscano, 2025. "Enhancing Recognition and Categorization of Skin Lesions with Tailored Deep Convolutional Networks and Robust Data Augmentation Techniques," Mathematics, MDPI, vol. 13(9), pages 1-36, April.
  • Handle: RePEc:gam:jmathe:v:13:y:2025:i:9:p:1480-:d:1646634
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/2227-7390/13/9/1480/pdf
    Download Restriction: no

    File URL: https://www.mdpi.com/2227-7390/13/9/1480/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Andre Esteva & Brett Kuprel & Roberto A. Novoa & Justin Ko & Susan M. Swetter & Helen M. Blau & Sebastian Thrun, 2017. "Correction: Corrigendum: Dermatologist-level classification of skin cancer with deep neural networks," Nature, Nature, vol. 546(7660), pages 686-686, June.
    2. Andre Esteva & Brett Kuprel & Roberto A. Novoa & Justin Ko & Susan M. Swetter & Helen M. Blau & Sebastian Thrun, 2017. "Dermatologist-level classification of skin cancer with deep neural networks," Nature, Nature, vol. 542(7639), pages 115-118, February.
    3. Rao Youlan & Lee Yoonkyung & Jarjoura David & Ruppert Amy S & Liu Chang-gong & Hsu Jason C & Hagan John P, 2008. "A Comparison of Normalization Techniques for MicroRNA Microarray Data," Statistical Applications in Genetics and Molecular Biology, De Gruyter, vol. 7(1), pages 1-20, July.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Majd Oteibi & Adam Tamimi & Kaneez Abbas & Gabriel Tamimi & Danesh Khazaei & Hadi Khazaei, 2024. "Advancing Digital Health using AI and Machine Learning Solutions for Early Ultrasonic Detection of Breast Disorders in Women," International Journal of Research and Scientific Innovation, International Journal of Research and Scientific Innovation (IJRSI), vol. 11(11), pages 518-527, November.
    2. Lin Lu & Laurent Dercle & Binsheng Zhao & Lawrence H. Schwartz, 2021. "Deep learning for the prediction of early on-treatment response in metastatic colorectal cancer from serial medical imaging," Nature Communications, Nature, vol. 12(1), pages 1-11, December.
    3. Zheng Yan & Wenqian Robertson & Yaosheng Lou & Tom W. Robertson & Sung Yong Park, 2021. "Finding leading scholars in mobile phone behavior: a mixed-method analysis of an emerging interdisciplinary field," Scientometrics, Springer;Akadémiai Kiadó, vol. 126(12), pages 9499-9517, December.
    4. Freddy Gabbay & Rotem Lev Aharoni & Ori Schweitzer, 2022. "Deep Neural Network Memory Performance and Throughput Modeling and Simulation Framework," Mathematics, MDPI, vol. 10(21), pages 1-20, November.
    5. Ting Wang & Boyang Zang & Chui Kong & Yigang Li & Xiaomin Yang & Yi Yu, 2025. "Intelligent and precise auxiliary diagnosis of breast tumors using deep learning and radiomics," PLOS ONE, Public Library of Science, vol. 20(6), pages 1-11, June.
    6. Sonika Darshan, 2024. "Data Mining for Disease Diagnosis: A Review of Machine Learning Approaches in Healthcare," Journal of Artificial Intelligence General science (JAIGS) ISSN:3006-4023, Open Knowledge, vol. 6(1), pages 716-726.
    7. Jungyoon Kim & Jihye Lim, 2021. "A Deep Neural Network-Based Method for Prediction of Dementia Using Big Data," IJERPH, MDPI, vol. 18(10), pages 1-13, May.
    8. Gang Yu & Kai Sun & Chao Xu & Xing-Hua Shi & Chong Wu & Ting Xie & Run-Qi Meng & Xiang-He Meng & Kuan-Song Wang & Hong-Mei Xiao & Hong-Wen Deng, 2021. "Accurate recognition of colorectal cancer with semi-supervised deep learning on pathological images," Nature Communications, Nature, vol. 12(1), pages 1-13, December.
    9. DonHee Lee & Seong No Yoon, 2021. "Application of Artificial Intelligence-Based Technologies in the Healthcare Industry: Opportunities and Challenges," IJERPH, MDPI, vol. 18(1), pages 1-18, January.
    10. Shang Li & Fei Yu & Shankou Zhang & Huige Yin & Hairong Lin, 2025. "Optimization of Direct Convolution Algorithms on ARM Processors for Deep Learning Inference," Mathematics, MDPI, vol. 13(5), pages 1-19, February.
    11. Claus Zippel & Sabine Bohnet-Joschko, 2021. "Rise of Clinical Studies in the Field of Machine Learning: A Review of Data Registered in ClinicalTrials.gov," IJERPH, MDPI, vol. 18(10), pages 1-14, May.
    12. Dario Sipari & Betsy D. M. Chaparro-Rico & Daniele Cafolla, 2022. "SANE (Easy Gait Analysis System): Towards an AI-Assisted Automatic Gait-Analysis," IJERPH, MDPI, vol. 19(16), pages 1-27, August.
    13. Darko B. Vuković & Senanu Dekpo-Adza & Stefana Matović, 2025. "AI integration in financial services: a systematic review of trends and regulatory challenges," Palgrave Communications, Palgrave Macmillan, vol. 12(1), pages 1-29, December.
    14. Jamil Ahmad & Abdul Khader Jilani Saudagar & Khalid Mahmood Malik & Waseem Ahmad & Muhammad Badruddin Khan & Mozaherul Hoque Abul Hasanat & Abdullah AlTameem & Mohammed AlKhathami & Muhammad Sajjad, 2022. "Disease Progression Detection via Deep Sequence Learning of Successive Radiographic Scans," IJERPH, MDPI, vol. 19(1), pages 1-16, January.
    15. Sarah Haggenmüller & Christoph Wies & Julia Abels & Jana T. Winterstein & Lukas Heinlein & Carina Nogueira Garcia & Jochen S. Utikal & Sebastian A. Wohlfeil & Friedegund Meier & Sarah Hobelsberger & F, 2025. "Discordance, accuracy and reproducibility study of pathologists’ diagnosis of melanoma and melanocytic tumors," Nature Communications, Nature, vol. 16(1), pages 1-8, December.
    16. Rasheed Omobolaji Alabi & Alhadi Almangush & Mohammed Elmusrati & Ilmo Leivo & Antti Mäkitie, 2022. "Measuring the Usability and Quality of Explanations of a Machine Learning Web-Based Tool for Oral Tongue Cancer Prognostication," IJERPH, MDPI, vol. 19(14), pages 1-13, July.
    17. Walter Leal Filho & João Henrique Paulino Pires Eustachio & Andreea Corina Nita (Danila) & Maria Alzira Pimenta Dinis & Amanda Lange Salvia & Debby R. E. Cotton & Kamila Frizzo & Laís Viera Trevisan &, 2024. "Using data science for sustainable development in higher education," Sustainable Development, John Wiley & Sons, Ltd., vol. 32(1), pages 15-28, February.
    18. Arnesh Telukdarie & Logistic Makoni & R. Raghunatha Sarma & Megashnee Munsamy & Sunil Kumar, 2025. "System Models for Synchronous Strategies in Operational Healthcare Forecasting," IJERPH, MDPI, vol. 22(2), pages 1-28, February.
    19. Andreas Fügener & Jörn Grahl & Alok Gupta & Wolfgang Ketter, 2022. "Cognitive Challenges in Human–Artificial Intelligence Collaboration: Investigating the Path Toward Productive Delegation," Information Systems Research, INFORMS, vol. 33(2), pages 678-696, June.
    20. Vidhya V. & Anjan Gudigar & U. Raghavendra & Ajay Hegde & Girish R. Menon & Filippo Molinari & Edward J. Ciaccio & U. Rajendra Acharya, 2021. "Automated Detection and Screening of Traumatic Brain Injury (TBI) Using Computed Tomography Images: A Comprehensive Review and Future Perspectives," IJERPH, MDPI, vol. 18(12), pages 1-29, June.

    More about this item

    Keywords

    ;
    ;
    ;
    ;
    ;

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jmathe:v:13:y:2025:i:9:p:1480-:d:1646634. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.