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A New Measure for an Acceptable Level of Homogeneity in Meta-Informatics

Author

Listed:
  • Ramalingam Shanmugam

    (School of Health Administration, Texas State University, San Marcos, TX 78666, USA)

  • Karan P. Singh

    (Department of Epidemiology and Biostatistics, School of Medicine, Health Science Center, The University of Texas at Tyler Health Science Center, 11937 US Highway 271, Tyler, TX 75708, USA)

Abstract

This paper addresses the challenges in assessing heterogeneity in meta-analytic studies. The specifics include mental health research work. Three key statistical scores in meta-analytics—Higgins’ I 2 , Birge’s H 2 , and the newly developed S 2 score—are discussed and illustrated. The paper critiques the subjectivity of these scores and introduces elasticity to enhance the accuracy and objectivity in assessing heterogeneity. The integration of elasticity into the meta-informatic score measures how heterogeneity changes as new studies are added, improving the interpretation of meta-analytic results. Also, the authors compute and compare elasticity scores in the context of mental health research, offering a novel approach to visualizing and quantifying heterogeneity. The authors demonstrate how elasticity improves the assessment of heterogeneity. The paper recommends the use of the meta-informatic S 2 score, integrated with elasticity, for more reliable and objective conclusions in mental health as well as in other meta-analyses. The new rectified score, S 2 , overcomes issues with the I 2 score when the chi-squared distribution fails due to small sample sizes or negative values.

Suggested Citation

  • Ramalingam Shanmugam & Karan P. Singh, 2025. "A New Measure for an Acceptable Level of Homogeneity in Meta-Informatics," Mathematics, MDPI, vol. 13(9), pages 1-17, April.
  • Handle: RePEc:gam:jmathe:v:13:y:2025:i:9:p:1364-:d:1639668
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