IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v6y2009i11p2763-2782d6100.html
   My bibliography  Save this article

Alcoholic Pancreatitis: Pathogenesis, Incidence and Treatment with Special Reference to the Associated Pain

Author

Listed:
  • Raffaele Pezzilli

    (Department of Digestive Diseases and Internal Medicine, Sant‘ Orsola-Malpighi Hospital, Via Massarenti 9, 40138 Bologna, Italy)

  • Antonio M. Morselli-Labate

    (Department of Digestive Diseases and Internal Medicine, Sant‘ Orsola-Malpighi Hospital, Via Massarenti 9, 40138 Bologna, Italy)

Abstract

Alcoholic pancreatitis continues to stir up controversy. One of the most debated points is whether from onset it is a chronic disease or whether it progresses to a chronic form after repeated episodes of acute pancreatitis. Histological studies on patients with alcoholic pancreatitis have shown that the disease is chronic from onset and that alcoholic acute pancreatitis occurs in a pancreas already damaged by chronic lesions. Genetic factors may also play a role in the pathogenesis of alcoholic disease. The incidence of chronic alcoholic pancreatitis seems to have decreased in the last twenty years. Finally, recent therapeutic studies which have shown medical or surgical approaches capable of reducing the pain episodes in chronic pancreatitis patients will be described.

Suggested Citation

  • Raffaele Pezzilli & Antonio M. Morselli-Labate, 2009. "Alcoholic Pancreatitis: Pathogenesis, Incidence and Treatment with Special Reference to the Associated Pain," IJERPH, MDPI, vol. 6(11), pages 1-20, November.
    • Handle: RePEc:gam:jijerp:v:6:y:2009:i:11:p:2763-2782:d:6100
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/6/11/2763/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/6/11/2763/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Lufen Chang & Michael Karin, 2001. "Mammalian MAP kinase signalling cascades," Nature, Nature, vol. 410(6824), pages 37-40, March.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Kazunari Iwamoto & Yuki Shindo & Koichi Takahashi, 2016. "Modeling Cellular Noise Underlying Heterogeneous Cell Responses in the Epidermal Growth Factor Signaling Pathway," PLOS Computational Biology, Public Library of Science, vol. 12(11), pages 1-18, November.
    2. Thomas C Whisenant & David T Ho & Ryan W Benz & Jeffrey S Rogers & Robyn M Kaake & Elizabeth A Gordon & Lan Huang & Pierre Baldi & Lee Bardwell, 2010. "Computational Prediction and Experimental Verification of New MAP Kinase Docking Sites and Substrates Including Gli Transcription Factors," PLOS Computational Biology, Public Library of Science, vol. 6(8), pages 1-21, August.
    3. Chih-Chien Wang & Chih-Yun Huang & Meng-Chang Lee & Dung-Jang Tsai & Chia-Chun Wu & Sui-Lung Su, 2021. "Genetic association between TNF-α G-308A and osteoarthritis in Asians: A case–control study and meta-analysis," PLOS ONE, Public Library of Science, vol. 16(11), pages 1-15, November.
    4. Luca Marchetti & Rosario Lombardo & Corrado Priami, 2017. "HSimulator: Hybrid Stochastic/Deterministic Simulation of Biochemical Reaction Networks," Complexity, Hindawi, vol. 2017, pages 1-12, December.
    5. Jason W Locasale & Arup K Chakraborty, 2008. "Regulation of Signal Duration and the Statistical Dynamics of Kinase Activation by Scaffold Proteins," PLOS Computational Biology, Public Library of Science, vol. 4(6), pages 1-12, June.
    6. Lina Chen & Wan Li & Liangcai Zhang & Hong Wang & Weiming He & Jingxie Tai & Xu Li & Xia Li, 2011. "Disease Gene Interaction Pathways: A Potential Framework for How Disease Genes Associate by Disease-Risk Modules," PLOS ONE, Public Library of Science, vol. 6(9), pages 1-12, September.
    7. Peter Rashkov & Ian P Barrett & Robert E Beardmore & Claus Bendtsen & Ivana Gudelj, 2016. "Kinase Inhibition Leads to Hormesis in a Dual Phosphorylation-Dephosphorylation Cycle," PLOS Computational Biology, Public Library of Science, vol. 12(11), pages 1-15, November.
    8. Xubin Lu & Hui Jiang & Abdelaziz Adam Idriss Arbab & Bo Wang & Dingding Liu & Ismail Mohamed Abdalla & Tianle Xu & Yujia Sun & Zongping Liu & Zhangping Yang, 2023. "Investigating Genetic Characteristics of Chinese Holstein Cow’s Milk Somatic Cell Score by Genetic Parameter Estimation and Genome-Wide Association," Agriculture, MDPI, vol. 13(2), pages 1-17, January.
    9. Hany A Omar & Wafaa R Mohamed & Hany H Arab & El-Shaimaa A Arafa, 2016. "Tangeretin Alleviates Cisplatin-Induced Acute Hepatic Injury in Rats: Targeting MAPKs and Apoptosis," PLOS ONE, Public Library of Science, vol. 11(3), pages 1-18, March.
    10. Xiaocui Chen & Jing Li & Zuowang Cheng & Yinghua Xu & Xia Wang & Xiaorui Li & Dongmei Xu & Carolyn M. Kapron & Ju Liu, 2016. "Low Dose Cadmium Inhibits Proliferation of Human Renal Mesangial Cells via Activation of the JNK Pathway," IJERPH, MDPI, vol. 13(10), pages 1-12, October.
    11. Christopher C Govern & Arup K Chakraborty, 2009. "Signaling Cascades Modulate the Speed of Signal Propagation through Space," PLOS ONE, Public Library of Science, vol. 4(2), pages 1-7, February.
    12. Aysegul Yildiz & Ozgur Tanriverdi, 2017. "MAPK and AKT Pathway Intersection in Neuroblastoma Cells," Current Trends in Biomedical Engineering & Biosciences, Juniper Publishers Inc., vol. 2(1), pages 17-20, March.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:6:y:2009:i:11:p:2763-2782:d:6100. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.