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Crossing hazard functions in common survival models

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  • Zhang, Jiajia
  • Peng, Yingwei

Abstract

Crossing hazard functions have extensive applications in modeling survival data. However, existing studies in the literature mainly focus on comparing crossed hazard functions and estimating the time at which the hazard functions cross, and there is little theoretical work on conditions under which hazard functions from a model will have a crossing. In this paper, we investigate crossing status of hazard functions from the proportional hazards (PH) model, the accelerated hazard (AH) model, and the accelerated failure time (AFT) model. We provide and prove conditions under which the hazard functions from the AH and the AFT models have no crossings or a single crossing. A few examples are also provided to demonstrate how the conditions can be used to determine the crossing status of hazard functions from the three models.

Suggested Citation

  • Zhang, Jiajia & Peng, Yingwei, 2009. "Crossing hazard functions in common survival models," Statistics & Probability Letters, Elsevier, vol. 79(20), pages 2124-2130, October.
    • Handle: RePEc:eee:stapro:v:79:y:2009:i:20:p:2124-2130
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    References listed on IDEAS

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    1. Zhezhen Jin, 2003. "Rank-based inference for the accelerated failure time model," Biometrika, Biometrika Trust, vol. 90(2), pages 341-353, June.
    2. Zhezhen Jin & D. Y. Lin & Zhiliang Ying, 2006. "On least-squares regression with censored data," Biometrika, Biometrika Trust, vol. 93(1), pages 147-161, March.
    3. Zeng, Donglin & Lin, D.Y., 2007. "Efficient Estimation for the Accelerated Failure Time Model," Journal of the American Statistical Association, American Statistical Association, vol. 102, pages 1387-1396, December.
    4. Ying Qing Chen, 2001. "Accelerated Hazards Regression Model and Its Adequacy for Censored Survival Data," Biometrics, The International Biometric Society, vol. 57(3), pages 853-860, September.
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    2. Li, Haifen & Zhang, Jiajia & Tang, Yincai, 2012. "Induced smoothing for the semiparametric accelerated hazards model," Computational Statistics & Data Analysis, Elsevier, vol. 56(12), pages 4312-4319.
    3. Jiajia Zhang & Yingwei Peng & Ou Zhao, 2011. "A New Semiparametric Estimation Method for Accelerated Hazard Model," Biometrics, The International Biometric Society, vol. 67(4), pages 1352-1360, December.
    4. Jiajia Zhang & Timothy Hanson & Haiming Zhou, 2019. "Bayes factors for choosing among six common survival models," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 25(2), pages 361-379, April.
    5. Abdisalam Hassan Muse & Samuel Mwalili & Oscar Ngesa & Christophe Chesneau & Afrah Al-Bossly & Mahmoud El-Morshedy, 2022. "Bayesian and Frequentist Approaches for a Tractable Parametric General Class of Hazard-Based Regression Models: An Application to Oncology Data," Mathematics, MDPI, vol. 10(20), pages 1-41, October.
    6. Félix Belzunce & Carolina Martínez-Riquelme, 2019. "On the unimodality of the likelihood ratio with applications," Statistical Papers, Springer, vol. 60(1), pages 223-237, February.
    7. Zhang, Jiajia & Peng, Yingwei & Li, Haifen, 2013. "A new semiparametric estimation method for accelerated hazards mixture cure model," Computational Statistics & Data Analysis, Elsevier, vol. 59(C), pages 95-102.

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