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Maintenance of diversity in a hierarchical host–parasite model with balancing selection and reinfection

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  • Pokalyuk, Cornelia
  • Wakolbinger, Anton

Abstract

Inspired by DNA data of the human cytomegalovirus we propose a model of a two-type parasite population distributed over its hosts. The parasite is capable to persist in its host till the host dies, and to reinfect other hosts. To maintain type diversity within a host, balancing selection is assumed.

Suggested Citation

  • Pokalyuk, Cornelia & Wakolbinger, Anton, 2020. "Maintenance of diversity in a hierarchical host–parasite model with balancing selection and reinfection," Stochastic Processes and their Applications, Elsevier, vol. 130(2), pages 1119-1158.
  • Handle: RePEc:eee:spapps:v:130:y:2020:i:2:p:1119-1158
    DOI: 10.1016/j.spa.2019.04.009
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    References listed on IDEAS

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    1. Champagnat, Nicolas, 2006. "A microscopic interpretation for adaptive dynamics trait substitution sequence models," Stochastic Processes and their Applications, Elsevier, vol. 116(8), pages 1127-1160, August.
    2. Pokalyuk, Cornelia & Pfaffelhuber, Peter, 2013. "The ancestral selection graph under strong directional selection," Theoretical Population Biology, Elsevier, vol. 87(C), pages 25-33.
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