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Influence of sex on the incidence of colorectal cancer: considering the influence of gender mechanisms

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  • Martinez, Amalia
  • Hamieh, Nadine
  • Colineaux, Hélène
  • Kelly-Irving, Michelle
  • Grosclaude, Pascale
  • Wiernik, Emmanuel
  • Delpierre, Cyrille
  • Lamy, Sébastien

Abstract

Differences in colorectal cancer (CRC) incidence between men and women are documented, but the role of gender mechanisms in explaining these disparities remains underexplored. CRC, the third deadliest cancer worldwide, is often analyzed through “biological” sex differences, without a clear distinction between innate and socially acquired factors. Gender mechanisms, including social roles, behaviors, and access to healthcare, may significantly influence CRC risk.

Suggested Citation

  • Martinez, Amalia & Hamieh, Nadine & Colineaux, Hélène & Kelly-Irving, Michelle & Grosclaude, Pascale & Wiernik, Emmanuel & Delpierre, Cyrille & Lamy, Sébastien, 2025. "Influence of sex on the incidence of colorectal cancer: considering the influence of gender mechanisms," Social Science & Medicine, Elsevier, vol. 376(C).
    • Handle: RePEc:eee:socmed:v:376:y:2025:i:c:s0277953625003880
    DOI: 10.1016/j.socscimed.2025.118058
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    References listed on IDEAS

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    1. Springer, Kristen W. & Mager Stellman, Jeanne & Jordan-Young, Rebecca M., 2012. "Beyond a catalogue of differences: A theoretical frame and good practice guidelines for researching sex/gender in human health," Social Science & Medicine, Elsevier, vol. 74(11), pages 1817-1824.
    2. Sturley, Charlotte & Norman, Paul & Morris, Michelle & Downing, Amy, 2023. "Contrasting socio-economic influences on colorectal cancer incidence and survival in England and Wales," Social Science & Medicine, Elsevier, vol. 333(C).
    3. Mollborn, Stefanie & Lawrence, Elizabeth M. & Hummer, Robert A., 2020. "A gender framework for understanding health lifestyles," Social Science & Medicine, Elsevier, vol. 265(C).
    4. repec:osf:socarx:z8k3e_v1 is not listed on IDEAS
    5. Olivier Torrès & Alexandre Benzari & Christian Fisch & Jinia Mukerjee & Abdelaziz Swalhi & Roy Thurik, 2022. "Risk of burnout in French entrepreneurs during the COVID-19 crisis," Small Business Economics, Springer, vol. 58(2), pages 717-739, February.
    6. Elena Christina Schreibauer & Melina Hippler & Stephanie Burgess & Monika A. Rieger & Esther Rind, 2020. "Work-Related Psychosocial Stress in Small and Medium-Sized Enterprises: An Integrative Review," IJERPH, MDPI, vol. 17(20), pages 1-23, October.
    7. Kelly-Irving, Michelle & Delpierre, Cyrille, 2021. "A framework for understanding health inequalities over the life course: the embodiment dynamic and biological mechanisms of exogenous and endogenous origin," SocArXiv z8k3e, Center for Open Science.
    8. repec:plo:pone00:0131521 is not listed on IDEAS
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