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Application of Markov chain Monte Carlo methods to projecting cancer incidence and mortality


  • Isabelle Bray


Projections based on incidence and mortality data collected by cancer registries are important for estimating current rates in the short term, and public health planning in the longer term. Classical approaches are dependent on questionable parametric assumptions. We implement a Bayesian age-period-cohort model, allowing the inclusion of prior belief concerning the smoothness of the parameters. The model is described by a directed acyclic graph. Computations are carried out by using Markov chain Monte Carlo methods (implemented in BUGS) in which the degree of smoothing is learnt from the data. Results and convergence diagnostics are discussed for an exemplary data set. We then compare the Bayesian projections with other methods in a range of situations to demonstrate its flexibility and robustness. Copyright 2002 The Royal Statistical Society.

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  • Isabelle Bray, 2002. "Application of Markov chain Monte Carlo methods to projecting cancer incidence and mortality," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 51(2), pages 151-164.
  • Handle: RePEc:bla:jorssc:v:51:y:2002:i:2:p:151-164

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    Cited by:

    1. Yang, Bowen & Li, Jackie & Balasooriya, Uditha, 2015. "Using bootstrapping to incorporate model error for risk-neutral pricing of longevity risk," Insurance: Mathematics and Economics, Elsevier, vol. 62(C), pages 16-27.
    2. Kogure, Atsuyuki & Kurachi, Yoshiyuki, 2010. "A Bayesian approach to pricing longevity risk based on risk-neutral predictive distributions," Insurance: Mathematics and Economics, Elsevier, vol. 46(1), pages 162-172, February.
    3. Katrien Antonio & Anastasios Bardoutsos & Wilbert Ouburg, 2015. "Bayesian Poisson log-bilinear models for mortality projections with multiple populations," BAFFI CAREFIN Working Papers 1505, BAFFI CAREFIN, Centre for Applied Research on International Markets Banking Finance and Regulation, Universita' Bocconi, Milano, Italy.

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