IDEAS home Printed from https://ideas.repec.org/a/bla/jorssb/v70y2008i1p73-93.html
   My bibliography  Save this article

The combination of ecological and case-control data

Author

Listed:
  • Sebastien J.-P. A. Haneuse
  • Jonathan C. Wakefield

Abstract

Ecological studies, in which data are available at the level of the group, rather than at the level of the individual, are susceptible to a range of biases due to their inability to characterize within-group variability in exposures and confounders. To overcome these biases, we propose a hybrid design in which ecological data are supplemented with a sample of individual level case-control data. We develop the likelihood for this design and illustrate its benefits via simulation, both in bias reduction when compared with an ecological study and in efficiency gains relative to a conventional case-control study. An interesting special case of the design proposed is the situation where ecological data are supplemented with case-only data. The design is illustrated by using a data set of county-specific lung cancer mortality rates in the state of Ohio from 1988. Copyright 2008 Royal Statistical Society.

Suggested Citation

  • Sebastien J.-P. A. Haneuse & Jonathan C. Wakefield, 2008. "The combination of ecological and case-control data," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 70(1), pages 73-93.
  • Handle: RePEc:bla:jorssb:v:70:y:2008:i:1:p:73-93
    as

    Download full text from publisher

    File URL: http://www.blackwell-synergy.com/doi/abs/10.1111/j.1467-9868.2007.00628.x
    File Function: link to full text
    Download Restriction: Access to full text is restricted to subscribers.

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Jon Wakefield, 2004. "Ecological inference for 2 × 2 tables (with discussion)," Journal of the Royal Statistical Society Series A, Royal Statistical Society, vol. 167(3), pages 385-445.
    2. N. E. Breslow & N. Chatterjee, 1999. "Design and analysis of two-phase studies with binary outcome applied to Wilms tumour prognosis," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 48(4), pages 457-468.
    3. J. F. Lawless & J. D. Kalbfleisch & C. J. Wild, 1999. "Semiparametric methods for response-selective and missing data problems in regression," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 61(2), pages 413-438.
    4. Jon Wakefield, 2003. "Sensitivity Analyses for Ecological Regression," Biometrics, The International Biometric Society, vol. 59(1), pages 9-17, March.
    5. Manski, Charles F & Lerman, Steven R, 1977. "The Estimation of Choice Probabilities from Choice Based Samples," Econometrica, Econometric Society, vol. 45(8), pages 1977-1988, November.
    Full references (including those not matched with items on IDEAS)

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:bla:jorssb:v:70:y:2008:i:1:p:73-93. See general information about how to correct material in RePEc.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: (Wiley-Blackwell Digital Licensing) or (Christopher F. Baum). General contact details of provider: http://edirc.repec.org/data/rssssea.html .

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service hosted by the Research Division of the Federal Reserve Bank of St. Louis . RePEc uses bibliographic data supplied by the respective publishers.