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Role of Brain Derived Neurotrophic Factor in Inducing Childhood Obesity: Impact in Maternal Opioid Addiction

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Listed:
  • Irfan A
  • Atif AB
  • Nordin Simbak

    (Faculty of Medicine, Universiti Sultan Zainal Abidin, Malaysia)

  • Saima A

    (BRAI Network Center, School of Health Sciences, Universiti Sains Malaysia, Malaysia)

  • Ibrahim S

    (Department of Human Physiology, Faculty of Medicine, Bayero University Kano, Nigeria)

  • Ariff MT
  • Nasir Mohamad

    (Institute for Community Development and Quality of Life, Univerisiti Sultan Zainal Abidin, Malaysia)

  • Wisam A

    (Faculty of Medicine, UTAR, Malaysia)

Abstract

Pregnant females consuming drugs of abuse is becoming a adverse social problem. In these subjects increases the risk of complications during pregnancy, may permanently harm the infants cognitive functions. Obesity in children and adolescents is a worldwide health problem, linked to a variety of somatic, psychosocial and psychiatric complications. Brain-derived neurotrophic factor (BDNF) is a neurotrophin that plays an important role in control of feeding behavior, food intake regulation, energy metabolism and weight control. A common polymorphism of the BDNF genotype (Val66Met) has been associated with a range of forms of eating disorders, alterations in body mass index (BMI) values and obesity in adult populations. Its presence in the arcuate, ventro medial and para ventricular nuclei indicates its vital role in regulation of feeding and body weight. Obesity is presently so common within the world’s population that it is beginning to replace under nutrition and infectious diseases as the most crucial contributor to ill health.

Suggested Citation

  • Irfan A & Atif AB & Nordin Simbak & Saima A & Ibrahim S & Ariff MT & Nasir Mohamad & Wisam A, 2017. "Role of Brain Derived Neurotrophic Factor in Inducing Childhood Obesity: Impact in Maternal Opioid Addiction," Current Trends in Biomedical Engineering & Biosciences, Juniper Publishers Inc., vol. 8(1), pages 9-12, August.
    • Handle: RePEc:adp:jctbeb:v:8:y:2017:i:1:p:9-12
    DOI: 10.19080/CTBEB.2017.08.555727
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    References listed on IDEAS

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    1. Peter G. Kopelman, 2000. "Obesity as a medical problem," Nature, Nature, vol. 404(6778), pages 635-643, April.
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