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Interference RNAs in the Treatment of Hereditary and Acquired Diseases

Author

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  • Salazar Montes AM

    (Instituto de Investigación en Enfermedades Crónico-Degenerativas, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, México)

Abstract

Interference RNAs are non-coding RNAs produced naturally o synthetically that temporarily inhibit the gene expression of specific genes. With this technology, it is possible to introduce a siRNA molecule against a specific mRNA into the cells and reduce the synthesis of the protein encoded on that mRNA. This novel strategy has been used by several researchers worldwide in the medical area as treatment of many hereditary and acquired diseases. Here we presented several examples of the successful use of siRNA in several diseases with excellent and promising results offering a new field in the treatment of many diseases without effective treatment for its cure to this present day.

Suggested Citation

  • Salazar Montes AM, 2023. "Interference RNAs in the Treatment of Hereditary and Acquired Diseases," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 50(5), pages 41985-41992, May.
    • Handle: RePEc:abf:journl:v:50:y:2023:i:5:p:41985-41992
    DOI: 10.26717/BJSTR.2023.50.008001
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    References listed on IDEAS

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    1. Angélique Girard & Ravi Sachidanandam & Gregory J. Hannon & Michelle A. Carmell, 2006. "A germline-specific class of small RNAs binds mammalian Piwi proteins," Nature, Nature, vol. 442(7099), pages 199-202, July.
    2. Andrew Fire & SiQun Xu & Mary K. Montgomery & Steven A. Kostas & Samuel E. Driver & Craig C. Mello, 1998. "Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans," Nature, Nature, vol. 391(6669), pages 806-811, February.
    3. Martin Jinek & Jennifer A. Doudna, 2009. "A three-dimensional view of the molecular machinery of RNA interference," Nature, Nature, vol. 457(7228), pages 405-412, January.
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    • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
    • Z0 - Other Special Topics - - General

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