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Advances in Topographical Neuroanatomy

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  • Michael Besser AM

    (Clinical Professor and Lecturer in Surgical Anatomy, Sydney University, Australia)

Abstract

The classical teaching of the three membranes covering the brain, the pia, arachnoid and dura mater, has recently been redefined by the discovery of a fourth meningeal layer which is immunophenotypically distinct. This has been named the subarachnoid lymphatic membrane (SLYM) by Mollgard and, although only a few cells thick, divides the subarachnoid space into two different spaces bathed in cerebrospinal fluid (CSF). This newly discovered membrane surrounds the blood vessels in the subarachnoid space and is made up largely of immune cells aligning the relationship between the glymphatic system, CSF flow, brain homeostasis and the pathophysiology of neurodegenerative disorders such as Alzheimer’s disease [1].

Suggested Citation

  • Michael Besser AM, 2023. "Advances in Topographical Neuroanatomy," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 49(1), pages 40317-40320, February.
    • Handle: RePEc:abf:journl:v:49:y:2023:i:1:p:40317-40320
    DOI: 10.26717/BJSTR.2023.49.007750
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    References listed on IDEAS

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    1. Lauren M. Hablitz & Virginia Plá & Michael Giannetto & Hanna S. Vinitsky & Frederik Filip Stæger & Tanner Metcalfe & Rebecca Nguyen & Abdellatif Benrais & Maiken Nedergaard, 2020. "Circadian control of brain glymphatic and lymphatic fluid flow," Nature Communications, Nature, vol. 11(1), pages 1-11, December.
    2. Antoine Louveau & Igor Smirnov & Timothy J. Keyes & Jacob D. Eccles & Sherin J. Rouhani & J. David Peske & Noel C. Derecki & David Castle & James W. Mandell & Kevin S. Lee & Tajie H. Harris & Jonathan, 2015. "Structural and functional features of central nervous system lymphatic vessels," Nature, Nature, vol. 523(7560), pages 337-341, July.
    3. Humberto Mestre & Jeffrey Tithof & Ting Du & Wei Song & Weiguo Peng & Amanda M. Sweeney & Genaro Olveda & John H. Thomas & Maiken Nedergaard & Douglas H. Kelley, 2018. "Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension," Nature Communications, Nature, vol. 9(1), pages 1-9, December.
    4. Antoine Drieu & Siling Du & Steffen E. Storck & Justin Rustenhoven & Zachary Papadopoulos & Taitea Dykstra & Fenghe Zhong & Kyungdeok Kim & Susan Blackburn & Tornike Mamuladze & Oscar Harari & Celeste, 2022. "Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid," Nature, Nature, vol. 611(7936), pages 585-593, November.
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    • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
    • Z0 - Other Special Topics - - General

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