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Content
December 2018, Volume 564, Issue 7736
- 434-438 The translation of non-canonical open reading frames controls mucosal immunity
by Ruaidhrí Jackson & Lina Kroehling & Alexandra Khitun & Will Bailis & Abigail Jarret & Autumn G. York & Omair M. Khan & J. Richard Brewer & Mathias H. Skadow & Coco Duizer & Christian C. D. Harman & Lelina Chang & Piotr Bielecki & Angel G. Solis & Holly R. Steach & Sarah Slavoff & Richard A. Flavell - 439-443 Design of amidobenzimidazole STING receptor agonists with systemic activity
by Joshi M. Ramanjulu & G. Scott Pesiridis & Jingsong Yang & Nestor Concha & Robert Singhaus & Shu-Yun Zhang & Jean-Luc Tran & Patrick Moore & Stephanie Lehmann & H. Christian Eberl & Marcel Muelbaier & Jessica L. Schneck & Jim Clemens & Michael Adam & John Mehlmann & Joseph Romano & Angel Morales & James Kang & Lara Leister & Todd L. Graybill & Adam K. Charnley & Guosen Ye & Neysa Nevins & Kamelia Behnia & Amaya I. Wolf & Viera Kasparcova & Kelvin Nurse & Liping Wang & Ana C. Puhl & Yue Li & Michael Klein & Christopher B. Hopson & Jeffrey Guss & Marcus Bantscheff & Giovanna Bergamini & Michael A. Reilly & Yiqian Lian & Kevin J. Duffy & Jerry Adams & Kevin P. Foley & Peter J. Gough & Robert W. Marquis & James Smothers & Axel Hoos & John Bertin - 444-448 Controlling orthogonal ribosome subunit interactions enables evolution of new function
by Wolfgang H. Schmied & Zakir Tnimov & Chayasith Uttamapinant & Christopher D. Rae & Stephen D. Fried & Jason W. Chin - 449-450 Seven steps to boost your research career in 2019
by Chris Woolston - 462-462 Solstice
by John Gilbey
December 2018, Volume 564, Issue 7735
- 5-5 Gene therapy
by Herb Brody - 6-8 Prenatal gene therapy offers the earliest possible cure
by Sarah DeWeerdt - 9-9 Author Correction: Necroptosis microenvironment directs lineage commitment in liver cancer
by Marco Seehawer & Florian Heinzmann & Luana D’Artista & Jule Harbig & Pierre-François Roux & Lisa Hoenicke & Hien Dang & Sabrina Klotz & Lucas Robinson & Grégory Doré & Nir Rozenblum & Tae-Won Kang & Rishabh Chawla & Thorsten Buch & Mihael Vucur & Mareike Roth & Johannes Zuber & Tom Luedde & Bence Sipos & Thomas Longerich & Mathias Heikenwälder & Xin Wei Wang & Oliver Bischof & Lars Zender - 9-9 A genetically augmented future
by Ellen Wright Clayton - 10-10 Author Correction: Self-organization of a human organizer by combined Wnt and Nodal signalling
by I. Martyn & T. Y. Kanno & A. Ruzo & E. D. Siggia & A. H. Brivanlou - 10-11 Gene therapy targets epilepsy
by Liam Drew - 11-16 Author Correction: A global slowdown of tropical-cyclone translation speed
by James P. Kossin - 12-13 Gene therapy targets sickle-cell disease
by Anna Nowogrodzki - 14-15 Change the genes to fix the skin
by Kat Arney - 16-17 The genetic shortcut to antibody drugs
by Amanda Keener - 17-17 Publisher Correction: Principles of nucleosome organization revealed by single-cell micrococcal nuclease sequencing
by Binbin Lai & Weiwu Gao & Kairong Cui & Wanli Xie & Qingsong Tang & Wenfei Jin & Gangqing Hu & Bing Ni & Keji Zhao - 18-19 Designer viruses could be the secret to cheaper and better gene therapy
by Neil Savage - 20-22 Regulating the gene-therapy revolution
by Eric Bender - 23-23 Access and affordability for all
by Michael Sherman - 53-55 How Indian biotech is driving innovation
by Bianca Nogrady - 57-57 All eyes on the prize
by Catherine Armitage - 62-63 Yielding results to feed a people
by Hepeng Jia - 64-65 China’s place among the stars
by Mark Zastrow - 65-66 Small science grows large in new hands
by Sarah O’Meara - 66-68 Engineering a biomedical revolution
by Smriti Mallapaty - 68-69 Strong spending compounds chemistry prowess
by Hepeng Jia - 70-71 Quality deficit belies the hype
by Futao Huang - 70-71 Citations strength begins at home
by Vincent Larivière & Kaile Gong & Cassidy R. Sugimoto - 163-163 Students need guidance in languages they speak
by Clarissa Rios Rojas - 169-170 ‘Little Foot’ hominin emerges from stone after millions of years
by Colin Barras - 170-171 Machine learning helps to hunt down the cause of a paralysing illness
by Sara Reardon - 171-172 China backs bold plan to tear down journal paywalls
by Quirin Schiermeier - 172-173 Could the United Kingdom really build its own global satnav system?
by Declan Butler - 173-174 Cancer researchers seek to harness mysterious DNA ‘super-enhancers’
by Heidi Ledford - 174-175 Ebola detectives race to identify hidden sources of infection as outbreak spreads
by Amy Maxmen - 176-179 How the brain’s face code might unlock the mysteries of perception
by Alison Abbott - 180-182 The hunt for life below Antarctic ice
by Douglas Fox - 183-185 Debate ethics of embryo models from stem cells
by Nicolas Rivron & Martin Pera & Janet Rossant & Alfonso Martinez Arias & Magdalena Zernicka-Goetz & Jianping Fu & Susanne van den Brink & Annelien Bredenoord & Wybo Dondorp & Guido de Wert & Insoo Hyun & Megan Munsie & Rosario Isasi - 186-188 India: a turbulent tale of rivers, floods and monsoons
by Philip Ball - 187-187 The Wright brothers’ real story, cosmic chronology, and what happened to the megafauna: Books in brief
by Barbara Kiser - 188-189 Science in hand: how art and craft can boost reproducibility
by Roger Kneebone & Claudia Schlegel & Alan Spivey - 190-190 COP24 and SDGs — use same statistics please
by Francesco N. Tubiello - 190-190 No place for ‘trial by media’ in bullying allegations
by Grace Collord & Jyoti Nangalia & Luiza Moore - 190-190 NIH dollars go to too few US states
by Wayne P. Wahls - 190-190 Gene editing: who should decide?
by Akira Akabayashi & Eisuke Nakazawa & Arthur L. Caplan - 192-193 El Niño events will intensify under global warming
by Yoo-Geun Ham - 193-194 How cells hush a viral invader
by Parinaz Fozouni & Melanie Ott - 194-196 Adrenaline fuels a cytokine storm during immunotherapy
by Stanley R. RIddell - 196-197 Darwin’s finches choose parent lookalikes as mates
by Lewis G. Spurgin & Tracey Chapman - 197-199 An exciting tool for asymmetric synthesis
by Cheng Yang & Yoshihisa Inoue - 199-200 Bacterial defence molecules target viral DNA
by Martha R. J. Clokie - 201-206 Increased variability of eastern Pacific El Niño under greenhouse warming
by Wenju Cai & Guojian Wang & Boris Dewitte & Lixin Wu & Agus Santoso & Ken Takahashi & Yun Yang & Aude Carréric & Michael J. McPhaden - 207-212 Widespread but heterogeneous responses of Andean forests to climate change
by Belén Fadrique & Selene Báez & Álvaro Duque & Agustina Malizia & Cecilia Blundo & Julieta Carilla & Oriana Osinaga-Acosta & Lucio Malizia & Miles Silman & William Farfán-Ríos & Yadvinder Malhi & Kenneth R. Young & Francisco Cuesta C. & Jurgen Homeier & Manuel Peralvo & Esteban Pinto & Oswaldo Jadan & Nikolay Aguirre & Zhofre Aguirre & Kenneth J. Feeley - 213-218 A circuit from hippocampal CA2 to lateral septum disinhibits social aggression
by Felix Leroy & Jung Park & Arun Asok & David H. Brann & Torcato Meira & Lara M. Boyle & Eric W. Buss & Eric R. Kandel & Steven A. Siegelbaum - 219-224 Single-cell mapping of lineage and identity in direct reprogramming
by Brent A. Biddy & Wenjun Kong & Kenji Kamimoto & Chuner Guo & Sarah E. Waye & Tao Sun & Samantha A. Morris - 225-228 An entanglement-based wavelength-multiplexed quantum communication network
by Sören Wengerowsky & Siddarth Koduru Joshi & Fabian Steinlechner & Hannes Hübel & Rupert Ursin - 229-233 Experimental realization of on-chip topological nanoelectromechanical metamaterials
by Jinwoong Cha & Kun Woo Kim & Chiara Daraio - 234-239 Reversible superdense ordering of lithium between two graphene sheets
by Matthias Kühne & Felix Börrnert & Sven Fecher & Mahdi Ghorbani-Asl & Johannes Biskupek & Dominik Samuelis & Arkady V. Krasheninnikov & Ute Kaiser & Jurgen H. Smet - 240-243 Catalytic deracemization of chiral allenes by sensitized excitation with visible light
by Alena Hölzl-Hobmeier & Andreas Bauer & Alexandre Vieira Silva & Stefan M. Huber & Christoph Bannwarth & Thorsten Bach - 244-248 Deconstructive diversification of cyclic amines
by Jose B. Roque & Yusuke Kuroda & Lucas T. Göttemann & Richmond Sarpong - 249-253 Assessing the efficiency of changes in land use for mitigating climate change
by Timothy D. Searchinger & Stefan Wirsenius & Tim Beringer & Patrice Dumas - 254-257 Palaeolithic cave art in Borneo
by M. Aubert & P. Setiawan & A. A. Oktaviana & A. Brumm & P. H. Sulistyarto & E. W. Saptomo & B. Istiawan & T. A. Ma’rifat & V. N. Wahyuono & F. T. Atmoko & J.-X. Zhao & J. Huntley & P. S. C. Taçon & D. L. Howard & H. E. A. Brand - 258-262 Reward behaviour is regulated by the strength of hippocampus–nucleus accumbens synapses
by Tara A. LeGates & Mark D. Kvarta & Jessica R. Tooley & T. Chase Francis & Mary Kay Lobo & Meaghan C. Creed & Scott M. Thompson - 263-267 Trophoblast organoids as a model for maternal–fetal interactions during human placentation
by Margherita Y. Turco & Lucy Gardner & Richard G. Kay & Russell S. Hamilton & Malwina Prater & Michael S. Hollinshead & Alasdair McWhinnie & Laura Esposito & Ridma Fernando & Helen Skelton & Frank Reimann & Fiona M. Gribble & Andrew Sharkey & Steven G. E. Marsh & Stephen O’Rahilly & Myriam Hemberger & Graham J. Burton & Ashley Moffett - 268-272 Lineage tracking reveals dynamic relationships of T cells in colorectal cancer
by Lei Zhang & Xin Yu & Liangtao Zheng & Yuanyuan Zhang & Yansen Li & Qiao Fang & Ranran Gao & Boxi Kang & Qiming Zhang & Julie Y. Huang & Hiroyasu Konno & Xinyi Guo & Yingjiang Ye & Songyuan Gao & Shan Wang & Xueda Hu & Xianwen Ren & Zhanlong Shen & Wenjun Ouyang & Zemin Zhang - 273-277 Disruption of a self-amplifying catecholamine loop reduces cytokine release syndrome
by Verena Staedtke & Ren-Yuan Bai & Kibem Kim & Martin Darvas & Marco L. Davila & Gregory J. Riggins & Paul B. Rothman & Nickolas Papadopoulos & Kenneth W. Kinzler & Bert Vogelstein & Shibin Zhou - 278-282 NP220 mediates silencing of unintegrated retroviral DNA
by Yiping Zhu & Gary Z. Wang & Oya Cingöz & Stephen P. Goff - 283-286 A chemical defence against phage infection
by Sarah Kronheim & Martin Daniel-Ivad & Zhuang Duan & Sungwon Hwang & Andrew I. Wong & Ian Mantel & Justin R. Nodwell & Karen L. Maxwell - 287-290 Dna2 nuclease deficiency results in large and complex DNA insertions at chromosomal breaks
by Yang Yu & Nhung Pham & Bo Xia & Alma Papusha & Guangyu Wang & Zhenxin Yan & Guang Peng & Kaifu Chen & Grzegorz Ira - 291-292 The automatic-design tools that are changing synthetic biology
by Anna Nowogrodzki - 293-294 The scientists who feed us
by David Payne - 296-296 Cold heart
by Victoria Dixon
December 2018, Volume 564, Issue 7734
- 1-1 Stiff competition
by G. W. Milton - 1-3 Computer logic meets cell biology: how cell science is getting an upgrade
by Neil Savage - 2-4 Berger et al. reply
by J. B. Berger & H. N. G. Wadley & R. M. McMeeking - 5-5 Author Correction: A multi-cohort study of the immune factors associated with M. tuberculosis infection outcomes
by Roshni Roy Chowdhury & Francesco Vallania & Qianting Yang & Cesar Joel Lopez Angel & Fatoumatta Darboe & Adam Penn-Nicholson & Virginie Rozot & Elisa Nemes & Stephanus T. Malherbe & Katharina Ronacher & Gerhard Walzl & Willem Hanekom & Mark M. Davis & Jill Winter & Xinchun Chen & Thomas J. Scriba & Purvesh Khatri & Yueh-hsiu Chien - 6-6 Author Correction: Cryo-EM of the dynamin polymer assembled on lipid membrane
by Leopold Kong & Kem A. Sochacki & Huaibin Wang & Shunming Fang & Bertram Canagarajah & Andrew D. Kehr & William J. Rice & Marie-Paule Strub & Justin W. Taraska & Jenny E. Hinshaw - 7-7 How sure are you of your result? Put a number on it
by Steven N. Goodman - 7-7 Publisher Correction: Functional aspects of meningeal lymphatics in ageing and Alzheimer’s disease
by Sandro Da Mesquita & Antoine Louveau & Andrea Vaccari & Igor Smirnov & R. Chase Cornelison & Kathryn M. Kingsmore & Christian Contarino & Suna Onengut-Gumuscu & Emily Farber & Daniel Raper & Kenneth E. Viar & Romie D. Powell & Wendy Baker & Nisha Dabhi & Robin Bai & Rui Cao & Song Hu & Stephen S. Rich & Jennifer M. Munson & M. Beatriz Lopes & Christopher C. Overall & Scott T. Acton & Jonathan Kipnis - 8-8 Publisher Correction: Antibody and TLR7 agonist delay viral rebound in SHIV-infected monkeys
by Erica N. Borducchi & Jinyan Liu & Joseph P. Nkolola & Anthony M. Cadena & Wen-Han Yu & Stephanie Fischinger & Thomas Broge & Peter Abbink & Noe B. Mercado & Abishek Chandrashekar & David Jetton & Lauren Peter & Katherine McMahan & Edward T. Moseley & Elena Bekerman & Joseph Hesselgesser & Wenjun Li & Mark G. Lewis & Galit Alter & Romas Geleziunas & Dan H. Barouch - 13-14 CRISPR-baby scientist fails to satisfy critics
by David Cyranoski - 15-15 China set to launch first-ever spacecraft to the far side of the Moon
by Andrew Silver - 16-16 Venice anti-flood gates could wreck lagoon ecosystem
by Lou Del Bello - 17-18 Tehran’s drastic sinking exposed by satellite data
by Kate Ravilious - 18-19 Geologists are measuring bullet damage to ancient Middle Eastern settlements
by Sarah Wild - 20-23 These dusty young stars are changing the rules of planet-building
by Rebecca Boyle - 24-26 The silent epidemic killing more people than HIV, malaria or TB
by Ian Graber-Stiehl - 27-30 Emissions are still rising: ramp up the cuts
by Christiana Figueres & Corinne Le Quéré & Anand Mahindra & Oliver Bäte & Gail Whiteman & Glen Peters & Dabo Guan - 30-32 Global warming will happen faster than we think
by Yangyang Xu & Veerabhadran Ramanathan & David G. Victor - 32-34 Put more carbon in soils to meet Paris climate pledges
by Cornelia Rumpel & Farshad Amiraslani & Lydie-Stella Koutika & Pete Smith & David Whitehead & Eva Wollenberg - 36-38 Do luxe labs shape science?
by Kendall Powell - 37-37 Big oil in the dock, the influenza trail, and insects as icons: Books in brief
by Barbara Kiser - 39-39 Helmholtz mentored many Nobelists
by Sameen Ahmed Khan - 39-39 Plan S will hit some academic societies hard
by Michael Jennions & Rob Lanfear & Shinichi Nakagawa - 39-39 Boost university voices at COP24 UN climate meeting
by Samantha Basile & Michael Lerner & Keyon Rostamnezhad - 39-39 Brazil’s new government threatens food security and biodiversity
by Marina Demaria Venâncio & Kamila Pope & Stefan Sieber - 39-39 Road charges in real time are not a silver bullet
by Geertje Schuitema & Linda Steg - 42-43 The rocky road to biomolecules
by John A. Baross - 43-44 Elusive spin textures discovered
by Seonghoon Woo - 45-46 Exit route evolved into entry path in plants
by Danny J. Schnell - 46-47 Long-sought decay of the Higgs boson seen
by Boris Tuchming - 47-48 Reduced oxygen consumption by fat cells improves metabolic defects
by Nolwenn Joffin & Philipp E. Scherer - 49-50 Satellite pinpoints ammonia sources globally
by Mark A. Sutton & Clare M. Howard - 50-51 Location matters for insulin-producing cells
by Francesca M. Spagnoli - 53-58 Change in future climate due to Antarctic meltwater
by Ben Bronselaer & Michael Winton & Stephen M. Griffies & William J. Hurlin & Keith B. Rodgers & Olga V. Sergienko & Ronald J. Stouffer & Joellen L. Russell - 59-63 Abiotic synthesis of amino acids in the recesses of the oceanic lithosphere
by Bénédicte Ménez & Céline Pisapia & Muriel Andreani & Frédéric Jamme & Quentin P. Vanbellingen & Alain Brunelle & Laurent Richard & Paul Dumas & Matthieu Réfrégiers - 64-70 Amphioxus functional genomics and the origins of vertebrate gene regulation
by Ferdinand Marlétaz & Panos N. Firbas & Ignacio Maeso & Juan J. Tena & Ozren Bogdanovic & Malcolm Perry & Christopher D. R. Wyatt & Elisa Calle-Mustienes & Stephanie Bertrand & Demian Burguera & Rafael D. Acemel & Simon J. Heeringen & Silvia Naranjo & Carlos Herrera-Ubeda & Ksenia Skvortsova & Sandra Jimenez-Gancedo & Daniel Aldea & Yamile Marquez & Lorena Buono & Iryna Kozmikova & Jon Permanyer & Alexandra Louis & Beatriz Albuixech-Crespo & Yann Petillon & Anthony Leon & Lucie Subirana & Piotr J. Balwierz & Paul Edward Duckett & Ensieh Farahani & Jean-Marc Aury & Sophie Mangenot & Patrick Wincker & Ricard Albalat & Èlia Benito-Gutiérrez & Cristian Cañestro & Filipe Castro & Salvatore D’Aniello & David E. K. Ferrier & Shengfeng Huang & Vincent Laudet & Gabriel A. B. Marais & Pierre Pontarotti & Michael Schubert & Hervé Seitz & Ildiko Somorjai & Tokiharu Takahashi & Olivier Mirabeau & Anlong Xu & Jr-Kai Yu & Piero Carninci & Juan Ramon Martinez-Morales & Hugues Roest Crollius & Zbynek Kozmik & Matthew T. Weirauch & Jordi Garcia-Fernàndez & Ryan Lister & Boris Lenhard & Peter W. H. Holland & Hector Escriva & Jose Luis Gómez-Skarmeta & Manuel Irimia - 71-76 PtdIns4P on dispersed trans-Golgi network mediates NLRP3 inflammasome activation
by Jueqi Chen & Zhijian J. Chen - 77-82 Type 9 secretion system structures reveal a new protein transport mechanism
by Frédéric Lauber & Justin C. Deme & Susan M. Lea & Ben C. Berks - 87-90 Atomic clock performance enabling geodesy below the centimetre level
by W. F. McGrew & X. Zhang & R. J. Fasano & S. A. Schäffer & K. Beloy & D. Nicolodi & R. C. Brown & N. Hinkley & G. Milani & M. Schioppo & T. H. Yoon & A. D. Ludlow - 91-94 Extreme-ultraviolet refractive optics
by L. Drescher & O. Kornilov & T. Witting & G. Reitsma & N. Monserud & A. Rouzée & J. Mikosch & M. J. J. Vrakking & B. Schütte - 95-98 Transformation between meron and skyrmion topological spin textures in a chiral magnet
by X. Z. Yu & W. Koshibae & Y. Tokunaga & K. Shibata & Y. Taguchi & N. Nagaosa & Y. Tokura - 99-103 Industrial and agricultural ammonia point sources exposed
by Martin Van Damme & Lieven Clarisse & Simon Whitburn & Juliette Hadji-Lazaro & Daniel Hurtmans & Cathy Clerbaux & Pierre-François Coheur - 104-108 Nonlinear rise in Greenland runoff in response to post-industrial Arctic warming
by Luke D. Trusel & Sarah B. Das & Matthew B. Osman & Matthew J. Evans & Ben E. Smith & Xavier Fettweis & Joseph R. McConnell & Brice P. Y. Noël & Michiel R. Broeke - 109-113 The hippocampus is crucial for forming non-hippocampal long-term memory during sleep
by Anuck Sawangjit & Carlos N. Oyanedel & Niels Niethard & Carolina Salazar & Jan Born & Marion Inostroza - 114-118 Mechanosignalling via integrins directs fate decisions of pancreatic progenitors
by Anant Mamidi & Christy Prawiro & Philip A. Seymour & Kristian Honnens Lichtenberg & Abigail Jackson & Palle Serup & Henrik Semb - 119-124 VCAM-1+ macrophages guide the homing of HSPCs to a vascular niche
by Dantong Li & Wenzhi Xue & Mei Li & Mei Dong & Jianwei Wang & Xianda Wang & Xiyue Li & Kai Chen & Wenjuan Zhang & Shuang Wu & Yingqi Zhang & Lei Gao & Yujie Chen & Jianfeng Chen & Bo O. Zhou & Yi Zhou & Xuebiao Yao & Lin Li & Dianqing Wu & Weijun Pan - 125-129 TIC236 links the outer and inner membrane translocons of the chloroplast
by Yih-Lin Chen & Lih-Jen Chen & Chiung-Chih Chu & Po-Kai Huang & Jie-Ru Wen & Hsou-min Li - 130-135 FBXO38 mediates PD-1 ubiquitination and regulates anti-tumour immunity of T cells
by Xiangbo Meng & Xiwei Liu & Xingdong Guo & Shutan Jiang & Tingting Chen & Zhiqiang Hu & Haifeng Liu & Yibing Bai & Manman Xue & Ronggui Hu & Shao-cong Sun & Xiaolong Liu & Penghui Zhou & Xiaowu Huang & Lai Wei & Wei Yang & Chenqi Xu - 136-140 Stella safeguards the oocyte methylome by preventing de novo methylation mediated by DNMT1
by Yingfeng Li & Zhuqiang Zhang & Jiayu Chen & Wenqiang Liu & Weiyi Lai & Baodong Liu & Xiang Li & Liping Liu & Shaohua Xu & Qiang Dong & Mingzhu Wang & Xiaoya Duan & Jiajun Tan & Yong Zheng & Pumin Zhang & Guoping Fan & Jiemin Wong & Guo-Liang Xu & Zhigao Wang & Hailin Wang & Shaorong Gao & Bing Zhu - 141-145 CDK12 regulates DNA repair genes by suppressing intronic polyadenylation
by Sara J. Dubbury & Paul L. Boutz & Phillip A. Sharp - 147-149 Transparent tissues bring cells into focus for microscopy
by Michael Eisenstein - 151-152 Meet the supervisors who helped to shape four scientists’ careers
by Emily Sohn - 154-154 A beginner’s guide to space travel and seafood
by Steven Fischer
November 2018, Volume 563, Issue 7733
- 30-30 Author Correction: Phosphocode-dependent functional dichotomy of a common co-receptor in plant signalling
by Artemis Perraki & Thomas A. DeFalco & Paul Derbyshire & Julian Avila & David Séré & Jan Sklenar & Xingyun Qi & Lena Stransfeld & Benjamin Schwessinger & Yasuhiro Kadota & Alberto P. Macho & Shushu Jiang & Daniel Couto & Keiko U. Torii & Frank L. H. Menke & Cyril Zipfel - 31-31 Author Correction: Nearly all the sky is covered by Lyman-α emission around high-redshift galaxies
by L. Wisotzki & R. Bacon & J. Brinchmann & S. Cantalupo & P. Richter & J. Schaye & K. B. Schmidt & T. Urrutia & P. M. Weilbacher & M. Akhlaghi & N. Bouché & T. Contini & B. Guiderdoni & E. C. Herenz & H. Inami & J. Kerutt & F. Leclercq & R. A. Marino & M. Maseda & A. Monreal-Ibero & T. Nanayakkara & J. Richard & R. Saust & M. Steinmetz & M. Wendt - 32-32 Publisher Correction: The NORAD lncRNA assembles a topoisomerase complex critical for genome stability
by Mathias Munschauer & Celina T. Nguyen & Klara Sirokman & Christina R. Hartigan & Larson Hogstrom & Jesse M. Engreitz & Jacob C. Ulirsch & Charles P. Fulco & Vidya Subramanian & Jenny Chen & Monica Schenone & Mitchell Guttman & Steven A. Carr & Eric S. Lander - 33-33 Publisher Correction: Evidence that CD32a does not mark the HIV-1 latent reservoir
by Christa E. Osuna & So-Yon Lim & Jessica L. Kublin & Richard Apps & Elsa Chen & Talia M. Mota & Szu-Han Huang & Yanqin Ren & Nathaniel D. Bachtel & Athe M. Tsibris & Margaret E. Ackerman & R. Brad Jones & Douglas F. Nixon & James B. Whitney - 131-131 Digital revolution
by Richard Hodson - 132-135 How automation is changing work
by Michael Segal - 136-137 Making digital government a better government
by Neil Savage - 138-140 Searching for digital technology’s effects on well-being
by Simon Makin - 141-143 Managing expectations of artificial intelligence
by Jeff Hecht - 144-146 Saving the digital world
by Sedeer el-Showk - 147-148 Build an internet for, and from, us all
by Anasuya Sengupta & Siko Bouterse & Kira Allmann - 179-181 How science supports São Paulo
by Gustavo Faleiros - 601-601 First law of leadership: be human first, scientist second
by Alison Antes - 607-608 Genome-edited baby claim provokes international outcry
by David Cyranoski & Heidi Ledford - 608-609 ‘Marsquake’ hunter prepares to land on the red planet
by Alexandra Witze - 609-610 AI peer reviewers unleashed to ease publishing grind
by Douglas Heaven - 610-611 Can a major AI conference shed its reputation for hosting sexist behaviour?
by Holly Else - 611-612 Frustrated Alzheimer’s researchers seek better lab mice
by Sara Reardon - 613-615 First sun-dimming experiment will test a way to cool Earth
by Jeff Tollefson - 616-618 Does science have a bullying problem?
by Holly Else - 619-621 Statistical pitfalls of personalized medicine
by Stephen Senn - 621-623 A 100th birthday wish: uphold academic freedom in dark times
by Ehsan Masood - 624-625 The secret laws of success and status
by Mark Buchanan - 625-625 Loop quantum gravity redux, ancient automatons, and the weirdness of tropical flora: Books in brief
by Barbara Kiser - 626-626 Industry is more alarmed about reproducibility than academia
by Anton Bespalov & Adrian G. Barnett & C. Glenn Begley - 626-626 Fear holds back gene-edited crops — educate the public
by Walter P. Suza & Alexander W. Kena & Richard Akromah & Nassib Mugwanya & Michael F. Zeller - 626-626 Heat and soil vie for waste to cut emissions
by Karen L. Johnson & Steven A. Banwart & Caroline L. Peacock & Lynsay Blake - 626-626 Rat and bat hunt helped heal rift from colonial cruelty
by Tyrone Lavery & Esau Kekeubata & Tommy Esau & Tim Flannery & David MacLaren & Jackson Waneagea - 627-627 Osamu Shimomura (1928–2018)
by Georgina Ferry - 630-631 Past warming events in the Arctic linked to shifting winds in the Antarctic
by Nerilie J. Abram - 631-632 A newly discovered mechanism driving neuronal mutations in Alzheimer’s disease
by Guoliang Chai & Joseph G. Gleeson - 633-644 A spotlight on bacterial mutations for 75 years
by Manoshi S. Datta & Roy Kishony - 634-636 The not-so-dangerous lives of Neanderthals
by Marta Mirazón Lahr - 636-637 A glimpse into the heart of a quasar
by Erin Kara - 637-638 A bacterium’s enemy isn’t your friend
by Michael S. Gilmore & Ona K. Miller - 639-645 Somatic APP gene recombination in Alzheimer’s disease and normal neurons
by Ming-Hsiang Lee & Benjamin Siddoway & Gwendolyn E. Kaeser & Igor Segota & Richard Rivera & William J. Romanow & Christine S. Liu & Chris Park & Grace Kennedy & Tao Long & Jerold Chun - 646-651 Predictable and precise template-free CRISPR editing of pathogenic variants
by Max W. Shen & Mandana Arbab & Jonathan Y. Hsu & Daniel Worstell & Sannie J. Culbertson & Olga Krabbe & Christopher A. Cassa & David R. Liu & David K. Gifford & Richard I. Sherwood - 652-656 Structural plasticity of D3–D14 ubiquitin ligase in strigolactone signalling
by Nitzan Shabek & Fabrizio Ticchiarelli & Haibin Mao & Thomas R. Hinds & Ottoline Leyser & Ning Zheng - 661-665 Quantum control of surface acoustic-wave phonons
by K. J. Satzinger & Y. P. Zhong & H.-S. Chang & G. A. Peairs & A. Bienfait & Ming-Han Chou & A. Y. Cleland & C. R. Conner & É. Dumur & J. Grebel & I. Gutierrez & B. H. November & R. G. Povey & S. J. Whiteley & D. D. Awschalom & D. I. Schuster & A. N. Cleland - 666-670 Creation and control of multi-phonon Fock states in a bulk acoustic-wave resonator
by Yiwen Chu & Prashanta Kharel & Taekwan Yoon & Luigi Frunzio & Peter T. Rakich & Robert J. Schoelkopf - 671-675 Superfluorescence from lead halide perovskite quantum dot superlattices
by Gabriele Rainò & Michael A. Becker & Maryna I. Bodnarchuk & Rainer F. Mahrt & Maksym V. Kovalenko & Thilo Stöferle - 676-680 A structural transition in physical networks
by Nima Dehmamy & Soodabeh Milanlouei & Albert-László Barabási - 681-685 Abrupt ice-age shifts in southern westerly winds and Antarctic climate forced from the north
by Christo Buizert & Michael Sigl & Mirko Severi & Bradley R. Markle & Justin J. Wettstein & Joseph R. McConnell & Joel B. Pedro & Harald Sodemann & Kumiko Goto-Azuma & Kenji Kawamura & Shuji Fujita & Hideaki Motoyama & Motohiro Hirabayashi & Ryu Uemura & Barbara Stenni & Frédéric Parrenin & Feng He & T. J. Fudge & Eric J. Steig - 686-690 Similar cranial trauma prevalence among Neanderthals and Upper Palaeolithic modern humans
by Judith Beier & Nils Anthes & Joachim Wahl & Katerina Harvati - 691-695 Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1
by Teerawat Wiwatpanit & Sarah M. Lorenzen & Jorge A. Cantú & Chuan Zhi Foo & Ann K. Hogan & Freddie Márquez & John C. Clancy & Matthew J. Schipma & Mary Ann Cheatham & Anne Duggan & Jaime García-Añoveros - 696-700 Helios is a key transcriptional regulator of outer hair cell maturation
by Lauren Chessum & Maggie S. Matern & Michael C. Kelly & Stuart L. Johnson & Yoko Ogawa & Beatrice Milon & Mark McMurray & Elizabeth C. Driver & Andrew Parker & Yang Song & Gemma Codner & Christopher T. Esapa & Jack Prescott & Graham Trent & Sara Wells & Abigail K. Dragich & Gregory I. Frolenkov & Matthew W. Kelley & Walter Marcotti & Steve D. M. Brown & Ran Elkon & Michael R. Bowl & Ronna Hertzano - 701-704 Linking a cell-division gene and a suicide gene to define and improve cell therapy safety
by Qin Liang & Claudio Monetti & Maria V. Shutova & Eric J. Neely & Sabiha Hacibekiroglu & Huijuan Yang & Christopher Kim & Puzheng Zhang & Chengjin Li & Kristina Nagy & Maria Mileikovsky & Istvan Gyongy & Hoon-Ki Sung & Andras Nagy - 705-709 Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity
by David Gerlach & Yinglan Guo & Cristina De Castro & Sun-Hwa Kim & Katja Schlatterer & Fei-Fei Xu & Claney Pereira & Peter H. Seeberger & Sara Ali & Jeroen Codée & Wanchat Sirisarn & Berit Schulte & Christiane Wolz & Jesper Larsen & Antonio Molinaro & Bok Luel Lee & Guoqing Xia & Thilo Stehle & Andreas Peschel - 710-713 Cryptic connections illuminate pathogen transmission within community networks
by Joseph R. Hoyt & Kate E. Langwig & J. Paul White & Heather M. Kaarakka & Jennifer A. Redell & Allen Kurta & John E. DePue & William H. Scullon & Katy L. Parise & Jeffrey T. Foster & Winifred F. Frick & A. Marm Kilpatrick - 714-718 Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release
by Sho Morioka & Justin S. A. Perry & Michael H. Raymond & Christopher B. Medina & Yunlu Zhu & Liyang Zhao & Vlad Serbulea & Suna Onengut-Gumuscu & Norbert Leitinger & Sarah Kucenas & Jeffrey C. Rathmell & Liza Makowski & Kodi S. Ravichandran - 719-723 Mannose impairs tumour growth and enhances chemotherapy
by Pablo Sierra Gonzalez & James O’Prey & Simone Cardaci & Valentin J. A. Barthet & Jun-ichi Sakamaki & Florian Beaumatin & Antonia Roseweir & David M. Gay & Gillian Mackay & Gaurav Malviya & Elżbieta Kania & Shona Ritchie & Alice D. Baudot & Barbara Zunino & Agata Mrowinska & Colin Nixon & Darren Ennis & Aoisha Hoyle & David Millan & Iain A. McNeish & Owen J. Sansom & Joanne Edwards & Kevin M. Ryan - 725-727 Juggling research and family life: honest reflections from scientist dads
by David Payne - 730-730 So, one of those tiny alien spaceships has flown into your house. Now what?
by Laura Pearlman
November 2018, Volume 563, Issue 7732
- 26-26 Author Correction: Global land change from 1982 to 2016
by Xiao-Peng Song & Matthew C. Hansen & Stephen V. Stehman & Peter V. Potapov & Alexandra Tyukavina & Eric F. Vermote & John R. Townshend - 27-27 Author Correction: EZH2 inhibition sensitizes BRG1 and EGFR mutant lung tumours to TopoII inhibitors
by Christine M. Fillmore & Chunxiao Xu & Pooja T. Desai & Joanne M. Berry & Samuel P. Rowbotham & Yi-Jang Lin & Haikuo Zhang & Victor E. Marquez & Peter S. Hammerman & Kwok-Kin Wong & Carla F. Kim - 28-28 Publisher Correction: Xenon isotopic constraints on the history of volatile recycling into the mantle
by Rita Parai & Sujoy Mukhopadhyay - 29-29 Publisher Correction: Magnetoelectric inversion of domain patterns
by N. Leo & V. Carolus & J. S. White & M. Kenzelmann & M. Hudl & P. Tolédano & T. Honda & T. Kimura & S. A. Ivanov & M. Weil & Th. Lottermoser & D. Meier & M. Fiebig - 83-83 Skin
by Lauren Gravitz - 84-85 Superpowered skin
by Julie Gould - 86-88 Unlocking the secrets of scar-free skin healing
by Cassandra Willyard - 89-90 When skin’s defence against pollution fails
by Elizabeth Svoboda - 91-93 Skin microbiota’s community effort
by Emily Sohn - 94-95 The edible skincare diet
by Sarah DeWeerdt - 96-98 Moving skin beyond the biological
by Katherine Bourzac - 99-99 Vitiligo’s impact is in the eye of the beholder
by John Harris - 445-445 America, don’t throw global talent away
by William Kerr - 451-452 Largest overhaul of scientific units since 1875 wins approval
by Elizabeth Gibney - 452-453 Brexit: what the draft deal means for science
by Elizabeth Gibney & Holly Else - 453-453 Lab-grown ‘mini brains’ produce electrical patterns that resemble those of premature babies
by Sara Reardon - 454-455 Ban on ‘gene drives’ is back on the UN’s agenda — worrying scientists
by Ewen Callaway - 455-456 Antarctic scientists begin hunt for sky’s ‘detergent’
by Nicky Phillips - 456-457 World’s first automated volcano forecast predicts Mount Etna’s eruptions
by Shannon Hall - 458-460 Why extreme rains are gaining strength as the climate warms
by Alexandra Witze - 462-464 The microscope revolution that’s sweeping through materials science
by Rachel Courtland