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Content
October 2025, Volume 646, Issue 8085
- 619-626 Reduced Atlantic reef growth past 2 °C warming amplifies sea-level impacts
by Chris T. Perry & Didier M. Bakker & Alice E. Webb & Steeve Comeau & Ben P. Harvey & Christopher E. Cornwall & Lorenzo Alvarez-Filip & Esmeralda Pérez-Cervantes & John Morris & Ian C. Enochs & Lauren T. Toth & Aaron O’Dea & Erin M. Dillon & Erik H. Meesters & William F. Precht - 627-636 Patterned invagination prevents mechanical instability during gastrulation
by Bruno C. Vellutini & Marina B. Cuenca & Abhijeet Krishna & Alicja Szałapak & Carl D. Modes & Pavel Tomancak - 637-646 Divergent evolutionary strategies pre-empt tissue collision in gastrulation
by Bipasha Dey & Verena Kaul & Girish Kale & Maily Scorcelletti & Michiko Takeda & Yu-Chiun Wang & Steffen Lemke - 647-656 Parent-of-origin effects on complex traits in up to 236,781 individuals
by Robin J. Hofmeister & Théo Cavinato & Roya Karimi & Adriaan Graaf & Fanny-Dhelia Pajuste & Jaanika Kronberg & Nele Taba & Reedik Mägi & Marc Vaudel & Simone Rubinacci & Stefan Johansson & Lili Milani & Olivier Delaneau & Zoltán Kutalik - 657-666 Single-cell transcriptomic and genomic changes in the ageing human brain
by Ailsa M. Jeffries & Tianxiong Yu & Jennifer S. Ziegenfuss & Allie K. Tolles & Christina E. Baer & Cesar Bautista Sotelo & Yerin Kim & Zhiping Weng & Michael A. Lodato - 667-675 Network synchrony creates neural filters promoting quiescence in Drosophila
by Davide Raccuglia & Raquel Suárez-Grimalt & Laura Krumm & Anatoli Ender & Cédric B. Brodersen & Sridhar R. Jagannathan & Martin Freire Krück & Niccolò P. Pampaloni & Carolin Rauch & York Winter & Genevieve Yvon-Durocher & Richard Kempter & Jörg R. P. Geiger & David Owald - 676-686 Microglia regulate GABAergic neurogenesis in prenatal human brain through IGF1
by Diankun Yu & Samhita Jain & Andi Wangzhou & Beika Zhu & Wenyuan Shao & Elena J. Coley-O’Rourke & Stacy Florencio & JaeYeon Kim & Jennifer Ja-Yoon Choi & Mercedes F. Paredes & Tomasz J. Nowakowski & Eric J. Huang & Xianhua Piao - 687-696 Haematopoietic stem cell number is not solely defined by niche availability
by Shoichiro Takeishi & Tony Marchand & Wade R. Koba & Daniel K. Borger & Chunliang Xu & Chandan Guha & Aviv Bergman & Paul S. Frenette & Kira Gritsman & Ulrich Steidl - 697-706 Amygdala–liver signalling orchestrates glycaemic responses to stress
by J. R. E. Carty & K. Devarakonda & R. M. O’Connor & A. Krek & D. Espinoza & M. Jimenez-Gonzalez & A. Alvarsson & R. F. Hampton & R. Li & Y. Qiu & S. Petri & A. Shtekler & A. Rajbhandari & K. Conner & M. Bayne & D. Garibay & J. Martin & V. Lehmann & L. Wang & K. Beaumont & I. Kurland & G. C. Yuan & P. J. Kenny & S. A. Stanley - 707-715 Reprogramming neuroblastoma by diet-enhanced polyamine depletion
by Sarah Cherkaoui & Christina S. Turn & Yuan Yuan & Wenyun Lu & Lifeng Yang & Matthew J. McBride & Caroline Eigenmann & George E. Allen & Olesya O. Panasenko & Lu Zhang & Annette Vu & Kangning Liu & Yimei Li & Om H. Gandhi & Lea F. Surrey & Sandra D. Kienast & Sebastian A. Leidel & Michael Wierer & Eileen White & Joshua D. Rabinowitz & Michael D. Hogarty & Raphael J. Morscher - 716-723 The Virtual Lab of AI agents designs new SARS-CoV-2 nanobodies
by Kyle Swanson & Wesley Wu & Nash L. Bulaong & John E. Pak & James Zou - 724-733 Thymic epithelial cells amplify epigenetic noise to promote immune tolerance
by Noah Gamble & Jason A. Caldwell & Joshua McKeever & Caroline Kaiser & Alexandra Bradu & Peyton J. Dooley & Sandy Klemm & William J. Greenleaf & Narutoshi Hibino & Aaron R. Dinner & Andrew S. Koh - 734-745 Targeting G1–S-checkpoint-compromised cancers with cyclin A/B RxL inhibitors
by Shilpa Singh & Catherine E. Gleason & Min Fang & Yasmin N. Laimon & Vishal Khivansara & Shanhai Xie & Yavuz T. Durmaz & Aniruddha Sarkar & Kenneth Ngo & Varunika Savla & Yixiang Li & Muhannad Abu-Remaileh & Xinyue Li & Marie-Anais Locquet & Bishma Tuladhar & Ranya Odeh & Frances Hamkins-Indik & Daphne He & Miles W. Membreno & Meisam Nosrati & Nathan N. Gushwa & Siegfried S. F. Leung & Breena Fraga-Walton & Luis Hernandez & Miguel P. Baldomero & Bryan M. Lent & David Spellmeyer & Joshua F. Luna & Dalena Hoang & Yuliana Gritsenko & Manesh Chand & Megan K. DeMart & Sammy Metobo & Chinmay Bhatt & Justin A. Shapiro & Kai Yang & Nathan J. Dupper & Andrew T. Bockus & Jinshu Fang & Ramesh Bambal & Peadar Cremin & John G. Doench & James B. Aggen & Li-Fen Liu & Bernard Levin & Evelyn W. Wang & Iolanda Vendrell & Roman Fischer & Benedikt Kessler & Prafulla C. Gokhale & Sabina Signoretti & Alexander Spektor & Constantine Kreatsoulas & Marie Evangelista & Rajinder Singh & David J. Earp & Deepak Nijhawan & Pablo D. Garcia & Matthew G. Oser - 746-753 Cocaine chemogenetics blunts drug-seeking by synthetic physiology
by Juan L. Gomez & Christopher J. Magnus & Jordi Bonaventura & Oscar Solis & Fallon P. Curry & Marjorie R. Levinstein & Reece C. Budinich & Meghan L. Carlton & Emilya N. Ventriglia & Sherry Lam & Le Wang & Ingrid Schoenborn & William Dunne & Michael Michaelides & Scott M. Sternson - 754-758 Crystal structures of agonist-bound human cannabinoid receptor CB1
by Tian Hua & Kiran Vemuri & Spyros P. Nikas & Yiran Wu & Lu Qu & Mengchen Pu & Anisha Korde & Shan Jiang & Jo-Hao Ho & Gye Won Han & Kang Ding & Xuanxuan Li & Haiguang Liu & Michael A. Hanson & Suwen Zhao & Laura M. Bohn & Alexandros Makriyannis & Raymond C. Stevens & Zhi-Jie Liu - 759-762 Research assessment: a round-up for early-career researchers
by Holly Else - 763-765 Digital flocks, predators allow ecologists to simulate real-world animal behaviour
by Heather Richardson - 768-768 Defending Ohuira Bay, Mexico
by Rachael Pells
October 2025, Volume 646, Issue 8084
- 261-261 Prizes must recognize machine contributions to discovery
by Dashun Wang - 263-264 US serial killer case opens door to using cutting-edge DNA data in courts
by Katherine Bourzac - 264-266 NIH races to spend its 2025 grant money — but fewer projects win funding
by Max Kozlov - 266-267 China pledges to cut emissions by 2035: what does that mean for the climate?
by Xiaoying You - 267-268 Swapping old immune cells in the brain with fresh ones could treat disease
by Heidi Ledford - 268-269 Will your study change the world? This AI tool predicts the impact of your research
by Brian Owens - 269-270 Want to do disruptive science? Include more rookie researchers
by Katie Kavanagh - 270-270 See space fireworks and lightning spaghetti — September’s best science images
by Fred Schwaller & Katie Kavanagh - 272-275 AI models that lie, cheat and plot murder: how dangerous are LLMs really?
by Matthew Hutson - 276-278 Will AI ever win its own Nobel? Some predict a prize-worthy science discovery soon
by Jenna Ahart - 279-280 From fossil fuels to ‘green capitalism’: the dilemmas of a just energy transition
by Sophia Kalantzakos - 281-283 The cutting-edge medical approaches that could transform ageing
by Coleen T. Murphy - 283-283 Violin therapy: Books in brief
by Andrew Robinson - 284-286 Stop treating code like an afterthought: record, share and value it
by Roberto Di Cosmo & Sabrina Granger & Konrad Hinsen & Nicolas Jullien & Daniel Le Berre & Violaine Louvet & Camille Maumet & Clémentine Maurice & Raphaël Monat & Nicolas P. Rougier - 286-287 Customizable AI systems that anyone can adapt bring big opportunities — and even bigger risks
by Yarin Gal & Stephen Casper - 288-288 Microbe discovery holds promise for sustainable biotechnology
by Jie Li & Shuwen Liu & Hao Song & Shiming Ding - 288-288 Insect biodiversity monitoring must be expanded
by Kris A. G. Wyckhuys & Yves Basset & Owen T. Lewis - 288-288 Incentives accelerate progress on open access in Spain
by Wenceslao Arroyo-Machado & Daniel Torres-Salinas - 288-288 Stop destructive fishing in marine protected areas
by Jenna Sullivan-Stack & Estradivari & Elizabeth P. Pike & Fabrice Stephenson - 289-290 Ant queens produce sons of two distinct species
by Jessica Purcell - 290-291 Protests are infectious: mapping rural unrest in Revolutionary France
by Jack A. Goldstone - 292-293 Depriving brain tumours of an amino acid could enhance chemotherapy
by Daniel Mobilio & Sheila Singh - 293-295 Sacrificial metal speeds up synthesis of nano-alloys from multiple elements
by Yunqing Kang & Yusuke Yamauchi - 295-296 Ancient DNA clarifies the early history of the Slavs
by Steffen Patzold - 297-302 Southward impact excavated magma ocean at the lunar South Pole–Aitken basin
by Jeffrey C. Andrews-Hanna & William F. Bottke & Adrien Broquet & Alexander J. Evans & Gabriel Gowman & Brandon C. Johnson & James T. Keane & Janette N. Levin & Ananya Mallik & Simone Marchi & Samantha A. Moruzzi & Arkadeep Roy & Shigeru Wakita - 303-308 Low-overhead transversal fault tolerance for universal quantum computation
by Hengyun Zhou & Chen Zhao & Madelyn Cain & Dolev Bluvstein & Nishad Maskara & Casey Duckering & Hong-Ye Hu & Sheng-Tao Wang & Aleksander Kubica & Mikhail D. Lukin - 309-314 Quantum-amplified global-phase spectroscopy on an optical clock transition
by Leon Zaporski & Qi Liu & Gustavo Velez & Matthew Radzihovsky & Zeyang Li & Simone Colombo & Edwin Pedrozo-Peñafiel & Vladan Vuletić - 315-322 Heat-rechargeable computation in DNA logic circuits and neural networks
by Tianqi Song & Lulu Qian - 323-330 Isothermal solidification for high-entropy alloy synthesis
by Qiubo Zhang & Max C. Gallant & Yi Chen & Zhigang Song & Yang Liu & Qi Zheng & Linfeng Chen & Karen. C. Bustillo & Yu Huang & Kristin A. Persson & Haimei Zheng - 331-337 A ductile chromium–molybdenum alloy resistant to high-temperature oxidation
by Frauke Hinrichs & Georg Winkens & Lena Katharina Kramer & Gabriely Falcão & Ewa M. Hahn & Daniel Schliephake & Michael Konrad Eusterholz & Sandipan Sen & Mathias Christian Galetz & Haruyuki Inui & Alexander Kauffmann & Martin Heilmaier - 338-342 A room temperature rechargeable all-solid-state hydride ion battery
by Jirong Cui & Ren Zou & Weijin Zhang & Hong Wen & Jingyao Liu & Shangshang Wang & Shukun Liu & Hetong Chen & Wei Liu & Xiaohua Ju & Weiwei Wang & Tao Gan & Jiong Li & Jianping Guo & Teng He & Hujun Cao & Ping Chen - 343-350 Tailoring polymer electrolyte solvation for 600 Wh kg−1 lithium batteries
by Xue-Yan Huang & Chen-Zi Zhao & Wei-Jin Kong & Nan Yao & Zong-Yao Shuang & Pan Xu & Shuo Sun & Yang Lu & Wen-Ze Huang & Jin-Liang Li & Liang Shen & Xiang Chen & Jia-Qi Huang & Lynden A. Archer & Qiang Zhang - 351-357 Scalable total synthesis of saxitoxin and related natural products
by Yinliang Guo & Yiheng Li & Sihan Chen & Yige Wu & Oscar Poll & Zhouyang Ren & Zhonglin Liu & Roman Vlkolinsky & Michal Bajo & Christopher K. Prier & Kai-Jiong Xiao & Benjamin F. Cravatt & Marisa Roberto & Phil S. Baran - 358-364 Epidemiology models explain rumour spreading during France’s Great Fear of 1789
by Stefano Zapperi & Constant Varlet-Bertrand & Cécile Bastidon & Caterina A. M. Porta & Antoine Parent - 365-371 Engineered yeast provides rare but essential pollen sterols for honeybees
by Elynor Moore & Raquel T. Sousa & Stella Felsinger & Jonathan A. Arnesen & Jane D. Dyekjær & Dudley I. Farman & Rui F. S. Gonçalves & Philip C. Stevenson & Irina Borodina & Geraldine A. Wright - 372-377 One mother for two species via obligate cross-species cloning in ants
by Y. Juvé & C. Lutrat & A. Ha & A. Weyna & E. Lauroua & A. C. Afonso Silva & C. Roux & E. Schifani & C. Galkowski & C. Lebas & R. Allio & I. Stoyanov & N. Galtier & B. C. Schlick-Steiner & F. M. Steiner & D. Baas & B. Kaufmann & J. Romiguier - 378-383 Hominins on Sulawesi during the Early Pleistocene
by Budianto Hakim & Unggul Prasetyo Wibowo & Gerrit D. Bergh & Dida Yurnaldi & Renaud Joannes-Boyau & Akin Duli & Suryatman & Ratno Sardi & Indah Asikin Nurani & Mika Rizki Puspaningrum & Irfan Mahmud & Afdalah Haris & Khairun Al Anshari & Andi Muhammad Saiful & P. Arman Bungaran & Shinatria Adhityatama & Putra Hudlinas Muhammad & Anwar Akib & Nani Somba & Fakhri & Basran Burhan & Zubair Mas’ud & Mark W. Moore & Yinika L. Perston & Wenjing Yu & Maxime Aubert & Adam Brumm - 384-393 Ancient DNA connects large-scale migration with the spread of Slavs
by Joscha Gretzinger & Felix Biermann & Hellen Mager & Benedict King & Denisa Zlámalová & Luca Traverso & Guido A. Gnecchi Ruscone & Sanni Peltola & Elina Salmela & Gunnar U. Neumann & Rita Radzeviciute & Pavlína Ingrová & Radosław Liwoch & Iwona Wronka & Radomir Jurić & Anna Hyrchała & Barbara Niezabitowska-Wiśniewska & Bartłomiej Bartecki & Beata Borowska & Tomasz Dzieńkowski & Marcin Wołoszyn & Michał Wojenka & Jarosław Wilczyński & Małgorzata Kot & Eric Müller & Jörg Orschiedt & Gunita Zariņa & Päivi Onkamo & Falko Daim & Arnold Muhl & Ralf Schwarz & Marek Majer & Michael McCormick & Jan Květina & Tivadar Vida & Patrick J. Geary & Jiří Macháček & Mario Šlaus & Harald Meller & Walter Pohl & Zuzana Hofmanová & Johannes Krause - 394-403 A circuit that integrates drive state and social contact to gate mating
by Lindsey D. Salay & Doris Y. Tsao & David J. Anderson - 404-412 SLC45A4 is a pain gene encoding a neuronal polyamine transporter
by Steven J. Middleton & Sigurbjörn Markússon & Mikael Åkerlund & Justin C. Deme & Mandy Tseng & Wenqianglong Li & Sana R. Zuberi & Gabriel Kuteyi & Peter Sarkies & Georgios Baskozos & Jimena Perez-Sanchez & Adham Farah & Harry L. Hébert & Sylvanus Toikumo & Zhanru Yu & Susan Maxwell & Yin Y. Dong & Benedikt M. Kessler & Henry R. Kranzler & John E. Linley & Blair H. Smith & Susan M. Lea & Joanne L. Parker & Valeriya Lyssenko & Simon Newstead & David L. Bennett - 413-422 Rewiring of cortical glucose metabolism fuels human brain cancer growth
by Andrew J. Scott & Anjali Mittal & Baharan Meghdadi & Alexandra O’Brien & Justine Bailleul & Palavalasa Sravya & Abhinav Achreja & Weihua Zhou & Jie Xu & Angelica Lin & Kari Wilder-Romans & Ningning Liang & Ayesha U. Kothari & Navyateja Korimerla & Donna M. Edwards & Zhe Wu & Jiane Feng & Sophia Su & Li Zhang & Peter Sajjakulnukit & Anthony C. Andren & Junyoung O. Park & Johanna Hoeve & Vijay Tarnal & Kimberly A. Redic & Nathan R. Qi & Joshua L. Fischer & Ethan Yang & Michael S. Regan & Sylwia A. Stopka & Gerard Baquer & Krithika Suresh & Jann N. Sarkaria & Theodore S. Lawrence & Sriram Venneti & Nathalie Y. R. Agar & Erina Vlashi & Costas A. Lyssiotis & Wajd N. Al-Holou & Deepak Nagrath & Daniel R. Wahl - 423-432 Discovery of a widespread chemical signalling pathway in the Bacteroidota
by Luis Linares-Otoya & Jaden D. Shirkey & Bhuwan Khatri Chhetri & Amira Mira & Abhishek Biswas & Samuel L. Neff & Maria V. Linares-Otoya & Ye Chen & Julio V. Campos-Florian & Mayar L. Ganoza-Yupanqui & Philip D. Jeffrey & Frederick M. Hughson & Mohamed S. Donia - 433-441 A nanobody specific to prefusion glycoprotein B neutralizes HSV-1 and HSV-2
by Benjamin Vollmer & Henriette Ebel & Renate Rees & Julia Nentwig & Thomas Mulvaney & Jürgen Schünemann & Jens Krull & Maya Topf & Dirk Görlich & Kay Grünewald - 442-451 TCF1 and LEF1 promote B-1a cell homeostasis and regulatory function
by Qian Shen & Hao Wang & Jonathan A. Roco & Xiangpeng Meng & Marita Bosticardo & Marie Hodges & Michael Battaglia & Zhi-Ping Feng & Benjamin James Talks & Jason Powell & Vijaya Baskar Mahalingam Shanmugiah & Julia Chu & Najib M. Rahman & Alguili Elsheikh & Probir Chakravarty & Amalie Grenov & Max Emmerich & Ottavia M. Delmonte & Alexandra F. Freeman & Michael D. Keller & Brahim Belaid & Ilenia Papa & James C. Lee & Pablo F. Cañete & Paula Gonzalez-Figueroa & Yaoyuan Zhang & Hai-Hui Xue & Samra Turajlic & Luigi D. Notarangelo & Muzlifah Haniffa & Lee Ann Garrett-Sinha & Helen M. Parry & Nikolaos I. Kanellakis & Carola G. Vinuesa - 452-461 Axonal injury is a targetable driver of glioblastoma progression
by Melanie Clements & Wenhao Tang & Zan Florjanic Baronik & Holly Simpson Ragdale & Roger Oria & Dimitrios Volteras & Ian J. White & Gordon Beattie & Imran Uddin & Tchern Lenn & Rachel Lindsay & Sara Castro Devesa & Saketh R. Karamched & Mark F. Lythgoe & Vahid Shahrezaei & Valerie M. Weaver & Ryoichi Sugisawa & Federico Roncaroli & Samuel Marguerat & Ciaran S. Hill & Simona Parrinello - 462-473 Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy
by Erez N. Baruch & Frederico O. Gleber-Netto & Priyadharsini Nagarajan & Xiayu Rao & Shamima Akhter & Tuany Eichwald & Tongxin Xie & Mohammad Balood & Adebayo Adewale & Shorook Naara & Hinduja N. Sathishkumar & Shajedul Islam & William McCarthy & Brandi J. Mattson & Renata Ferrarotto & Michael K. Wong & Michael A. Davies & Sonali Jindal & Sreyashi Basu & Karine Roversi & Amin Reza Nikpoor & Maryam Ahmadi & Ali Ahmadi & Catherine Harwood & Irene Leigh & Dennis Gong & Paulino Tallón de Lara & Derrick L. Tao & Tara M. Davidson & Nadim J. Ajami & Andrew Futreal & Kunal Rai & Veena Kochat & Micah Castillo & Preethi Gunaratne & Ryan P. Goepfert & Sharia D. Hernandez & Nikhil I. Khushalani & Jing Wang & Stephanie S. Watowich & George A. Calin & Michael R. Migden & Mona Yuan & Naijiang Liu & Yi Ye & William L. Hwang & Paola D. Vermeer & Nisha J. D’Silva & Yuri L. Bunimovich & Dan Yaniv & Jared K. Burks & Javier Gomez & Patrick M. Dougherty & Kenneth Y. Tsai & James P. Allison & Padmanee Sharma & Jennifer A. Wargo & Jeffrey N. Myers & Sebastien Talbot & Neil D. Gross & Moran Amit - 474-482 Quantitative imaging of lipid transport in mammalian cells
by Juan M. Iglesias-Artola & Kristin Böhlig & Kai Schuhmann & Katelyn C. Cook & H. Mathilda Lennartz & Milena Schuhmacher & Pavel Barahtjan & Cristina Jiménez López & Radek Šachl & Vannuruswamy Garikapati & Karina Pombo-Garcia & Annett Lohmann & Petra Riegerová & Martin Hof & Björn Drobot & Andrej Shevchenko & Alf Honigmann & André Nadler - 483-492 One-shot design of functional protein binders with BindCraft
by Martin Pacesa & Lennart Nickel & Christian Schellhaas & Joseph Schmidt & Ekaterina Pyatova & Lucas Kissling & Patrick Barendse & Jagrity Choudhury & Srajan Kapoor & Ana Alcaraz-Serna & Yehlin Cho & Kourosh H. Ghamary & Laura Vinué & Brahm J. Yachnin & Andrew M. Wollacott & Stephen Buckley & Adrie H. Westphal & Simon Lindhoud & Sandrine Georgeon & Casper A. Goverde & Georgios N. Hatzopoulos & Pierre Gönczy & Yannick D. Muller & Gerald Schwank & Daan C. Swarts & Alex J. Vecchio & Bernard L. Schneider & Sergey Ovchinnikov & Bruno E. Correia - 493-500 Structural basis for the dynamic regulation of mTORC1 by amino acids
by Max L. Valenstein & Maximilian Wranik & Pranav V. Lalgudi & Karen Y. Linde-Garelli & Yuri Choi & Raghu R. Chivukula & David M. Sabatini & Kacper B. Rogala - 501-502 27 things we wish we’d known when we started our PhDs
by Linda Nordling - 503-505 Biothreat hunters catch dangerous DNA before it gets made
by Matthew Hutson - 508-508 Connecting the dots: I trace the history of the East Kolkata Wetlands
by Nikki Forrester
October 2025, Volume 646, Issue 8083
- 1-1 Author Correction: A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome
by Aline C. Simon & Jin C. Zhou & Rajika L. Perera & Frederick Deursen & Cecile Evrin & Marina E. Ivanova & Mairi L. Kilkenny & Ludovic Renault & Svend Kjaer & Dijana Matak-Vinković & Karim Labib & Alessandro Costa & Luca Pellegrini - 1-1 Hospitals have long been key for research, now their influence is broadening
by Jack Leeming - 2-2 Publisher Correction: Experimental determination of partial charges with electron diffraction
by Soheil Mahmoudi & Tim Gruene & Christian Schröder & Khalil D. Ferjaoui & Erik Fröjdh & Aldo Mozzanica & Kiyofumi Takaba & Anatoliy Volkov & Julian Maisriml & Vladimir Paunović & Jeroen A. van Bokhoven & Bernhard K. Keppler - 2-5 China’s research hospitals push for prominence
by Brian Owens - 3-3 Publisher Correction: TCF1 and LEF1 promote B-1a cell homeostasis and regulatory function
by Qian Shen & Hao Wang & Jonathan A. Roco & Xiangpeng Meng & Marita Bosticardo & Marie Hodges & Michael Battaglia & Zhi-Ping Feng & Benjamin James Talks & Jason Powell & Vijaya Baskar Mahalingam Shanmugiah & Julia Chu & Najib M. Rahman & Alguili Elsheikh & Probir Chakravarty & Amalie Grenov & Max Emmerich & Ottavia M. Delmonte & Alexandra F. Freeman & Michael D. Keller & Brahim Belaid & Ilenia Papa & James C. Lee & Pablo F. Cañete & Paula Gonzalez-Figueroa & Yaoyuan Zhang & Hai-Hui Xue & Samra Turajlic & Luigi D. Notarangelo & Muzlifah Haniffa & Lee Ann Garrett-Sinha & Helen M. Parry & Nikolaos I. Kanellakis & Carola G. Vinuesa - 8-10 Uniting Africa’s longitudinal cohorts
by Anna McKie - 9-9 Trust in the sea-bed mining authority is fragile — here’s how to change that
by Carlos Garcia-Soto - 10-10 Six journal rejections and a major rethink: why I’m happy to admit to my research failures, and you should too
by Séverine Toussaert - 10-12 Fixing the imbalance in cancer rates between Black and white women
by Anna McKie - 12-14 HELIOS: a microcosm of Asian health with global reach
by Anna McKie - 13-14 Trump links autism and Tylenol: is there any truth to it?
by Helen Pearson & Heidi Ledford - 15-15 Huntington’s disease treated for first time using gene therapy
by Elie Dolgin - 16-16 World’s first AI-designed viruses a step towards AI-generated life
by Katie Kavanagh - 17-18 Tipsy bats and perfect pasta: Ig Nobels celebrate ‘improbable’ research
by Chris Simms - 18-19 Can AI chatbots trigger psychosis? What the science says
by Rachel Fieldhouse - 19-20 The Moon is rusting — thanks to ‘wind’ blown all the way from Earth
by Alexandra Witze - 20-20 She lived to 117: what her genes and lifestyle tell us about longevity
by Mariana Lenharo - 22-25 AI is dreaming up millions of new materials. Are they any good?
by Mark Peplow - 26-28 How to get the best night’s sleep: what the science says
by Lynne Peeples - 29-30 Power and profit drive what we eat: here’s why the food system needs a revolution
by Laura Kelly - 31-34 Public trust in science has declined since COVID — virologists need to unite around safety standards
by Melanie Ott & Olivier Schwartz & Alex Sigal - 34-37 Technology leaders should ‘pay back’ society to support the common good
by Abilio Almeida - 38-38 India and Pakistan share flood risks and must combine solutions
by Saheeb Ahmed Kayani - 38-38 Add a ‘speculation box’ to research papers
by Milad Malekzadeh - 38-38 AI tools could reduce the appeal of predatory journals
by Alessandro Maria Selvitella & Kathleen Lois Foster - 38-38 Make cities more walkable, in the real world and in virtual reality
by Mohammad Javad Koohsari & Andrew T. Kaczynski - 39-40 Childhood eczema linked to mother’s stress during pregnancy
by Abhay P. S. Rathore & Soman N. Abraham - 40-42 Quantum correlations enhance the sensitivity of room-temperature sensors
by Maja S. Scharnagl & Klemens Hammerer - 42-43 People are more likely to cheat when they delegate tasks to AI
by Shoko Suzuki - 43-45 Parachutes inspired by the Japanese art of kirigami
by Pierre-Thomas Brun - 45-46 Rare skeletal condition caused by enzyme’s failure to rescue a catalytic cycle
by Karen N. Allen - 47-56 Doughnut of social and planetary boundaries monitors a world out of balance
by Andrew L. Fanning & Kate Raworth - 62-67 Late fluid flow in a primitive asteroid revealed by Lu–Hf isotopes in Ryugu
by Tsuyoshi Iizuka & Takazo Shibuya & Takehito Hayakawa & Tetsuya Yokoyama & Ikshu Gautam & Makiko K. Haba & Kengo T. M. Ito & Yuki Hibiya & Akira Yamaguchi & Yoshinari Abe & Jérôme Aléon & Conel M. O’D. Alexander & Sachiko Amari & Yuri Amelin & Ken-ichi Bajo & Martin Bizzarro & Audrey Bouvier & Richard W. Carlson & Marc Chaussidon & Byeon-Gak Choi & Nicolas Dauphas & Andrew M. Davis & Tommaso Rocco & Wataru Fujiya & Ryota Fukai & Hiroshi Hidaka & Hisashi Homma & Gary R. Huss & Trevor R. Ireland & Akira Ishikawa & Shoichi Itoh & Noriyuki Kawasaki & Noriko T. Kita & Koki Kitajima & Thorsten Kleine & Shintaro Komatani & Alexander N. Krot & Ming-Chang Liu & Yuki Masuda & Kazuko Motomura & Frédéric Moynier & Kazuhide Nagashima & Izumi Nakai & Ann Nguyen & Larry Nittler & Andreas Pack & Changkun Park & Laurette Piani & Liping Qin & Sara Russell & Naoya Sakamoto & Maria Schönbächler & Lauren Tafla & Haolan Tang & Kentaro Terada & Yasuko Terada & Tomohiro Usui & Sohei Wada & Meenakshi Wadhwa & Richard J. Walker & Katsuyuki Yamashita & Qing-Zhu Yin & Shigekazu Yoneda & Hiroharu Yui & Ai-Cheng Zhang & Tomoki Nakamura & Hiroshi Naraoka & Takaaki Noguchi & Ryuji Okazaki & Kanako Sakamoto & Hikaru Yabuta & Masanao Abe & Akiko Miyazaki & Aiko Nakato & Masahiro Nishimura & Tatsuaki Okada & Toru Yada & Kasumi Yogata & Satoru Nakazawa & Takanao Saiki & Satoshi Tanaka & Fuyuto Terui & Yuichi Tsuda & Sei-ichiro Watanabe & Makoto Yoshikawa & Shogo Tachibana & Hisayoshi Yurimoto - 68-73 Signal amplification in a solid-state sensor through asymmetric many-body echo
by Haoyang Gao & Leigh S. Martin & Lillian B. Hughes & Nathaniel T. Leitao & Piotr Put & Hengyun Zhou & Nazli U. Koyluoglu & Simon A. Meynell & Ania C. Bleszynski Jayich & Hongkun Park & Mikhail D. Lukin - 74-80 Spin squeezing in an ensemble of nitrogen–vacancy centres in diamond
by Weijie Wu & Emily J. Davis & Lillian B. Hughes & Bingtian Ye & Zilin Wang & Dominik Kufel & Tasuku Ono & Simon A. Meynell & Maxwell Block & Che Liu & Haopu Yang & Ania C. Bleszynski Jayich & Norman Y. Yao - 81-87 Industry-compatible silicon spin-qubit unit cells exceeding 99% fidelity
by Paul Steinacker & Nard Dumoulin Stuyck & Wee Han Lim & Tuomo Tanttu & MengKe Feng & Santiago Serrano & Andreas Nickl & Marco Candido & Jesus D. Cifuentes & Ensar Vahapoglu & Samuel K. Bartee & Fay E. Hudson & Kok Wai Chan & Stefan Kubicek & Julien Jussot & Yann Canvel & Sofie Beyne & Yosuke Shimura & Roger Loo & Clement Godfrin & Bart Raes & Sylvain Baudot & Danny Wan & Arne Laucht & Chih Hwan Yang & Andre Saraiva & Christopher C. Escott & Kristiaan Greve & Andrew S. Dzurak - 88-94 Kirigami-inspired parachutes with programmable reconfiguration
by Danick Lamoureux & Jérémi Fillion & Sophie Ramananarivo & Frédérick P. Gosselin & David Melancon - 95-101 Toughened self-assembled monolayers for durable perovskite solar cells
by Wenlin Jiang & Geping Qu & Xiaofeng Huang & Xia Chen & Linyuan Chi & Tonghui Wang & Chun-To Wong & Francis R. Lin & Chunlei Yang & Qing Jiang & Shengfan Wu & Jie Zhang & Alex K.-Y. Jen - 102-107 Probing the heterogeneous nature of LiF in solid–electrolyte interphases
by Xiangsi Liu & Shuyang Li & Chen Yuan & Bizhu Zheng & Gangya Cheng & Yufan Chen & Xingyu Lu & Danyu Gu & Baijiang Lv & Hao Li & Zihan Yan & Hui Qian & Yizhou Zhu & Dalin Sun & Yun Song & Yuxuan Xiang - 108-116 Connecting chemical and protein sequence space to predict biocatalytic reactions
by Alexandra E. Paton & Daniil A. Boiko & Jonathan C. Perkins & Nicholas I. Cemalovic & Thiago Reschützegger & Gabe Gomes & Alison R. H. Narayan - 117-125 Precisely defining disease variant effects in CRISPR-edited single cells
by Yuriy Baglaenko & Zepeng Mu & Michelle Curtis & Hafsa M. Mire & Vidyashree Jayanthi & Majd Al Suqri & Cassidy Liu & Ryan Agnew & Aparna Nathan & Annelise Yoo Mah-Som & David R. Liu & Gregory A. Newby & Soumya Raychaudhuri - 126-134 Delegation to artificial intelligence can increase dishonest behaviour
by Nils Köbis & Zoe Rahwan & Raluca Rilla & Bramantyo Ibrahim Supriyatno & Clara Bersch & Tamer Ajaj & Jean-François Bonnefon & Iyad Rahwan - 135-142 Eye structure shapes neuron function in Drosophila motion vision
by Arthur Zhao & Eyal Gruntman & Aljoscha Nern & Nirmala Iyer & Edward M. Rogers & Sanna Koskela & Igor Siwanowicz & Marisa Dreher & Miriam A. Flynn & Connor Laughland & Henrique Ludwig & Alexander Thomson & Cullen Moran & Bruck Gezahegn & Davi D. Bock & Michael B. Reiser - 143-151 Remodelling of corticostriatal axonal boutons during motor learning
by Mengjun Sheng & Di Lu & Richard H. Roth & Fuu-Jiun Hwang & Kaiwen Sheng & Jun B. Ding - 152-160 A novel bacterial protein family that catalyses nitrous oxide reduction
by Guang He & Weijiao Wang & Gao Chen & Yongchao Xie & Jerry M. Parks & Megan E. Davin & Robert L. Hettich & Konstantinos T. Konstantinidis & Frank E. Löffler - 161-170 Maternal stress triggers early-life eczema through fetal mast cell programming
by Nadine Serhan & Nasser S. Abdullah & Nadine Gheziel & Alexia Loste & Rüçhan Ekren & Elodie Labit & Anne-Alicia Gonzalez & Giulia Oliva & Pauline Tarot & Camille Petitfils & Gaëlle Payros & Paolo D’Avino & Allison Voisin & Holly Freya Grace Tinsley & Rebecca Gentek & Carole Brosseau & Marie Bodinier & Laurent Reber & Pierre Val & Cezmi A. Akdis & Yasutaka Mitamura & Anand Kumar Andiappan & Jerry Kok Yen Chan & Florent Ginhoux & Amaury François & Nicolas Cénac & Lilian Basso & Nicolas Gaudenzio - 171-179 EBV induces CNS homing of B cells attracting inflammatory T cells
by Fabienne Läderach & Ioannis Piteros & Éanna Fennell & Elena Bremer & Mette Last & Sandra Schmid & Lisa Rieble & Caroline Campbell & Isis Ludwig-Portugall & Lea Bornemann & Alexander Gruhl & Klaus Eulitz & Paul Gueguen & Juliane Mietz & Anne Müller & Gaetana Pezzino & Jürgen Schmitz & Guido Ferlazzo & Josef Mautner & Christian Münz - 180-189 mAChR4 suppresses liver disease via GAP-induced antimicrobial immunity
by Cristina Llorente & Fernanda Raya Tonetti & Ryan Bruellman & Rocío Brea & Nuria Pell & Phillipp Hartmann & Luca Maccioni & Hui Han & Noemí Cabré & Junlai Liu & Alvaro Eguileor & Marcos F. Fondevila & Abraham S. Meijnikman & Cynthia L. Hsu & Ameera Alghafri & Rongrong Zhou & Bei Gao & Yi Duan & Peng Zhang & Mark A. Febbraio & Koji Taniguchi & Rodney D. Newberry & Derrick E. Fouts & David A. Brenner & Peter Stärkel & Michael Karin & Bernd Schnabl - 190-197 Clone copy number diversity is linked to survival in lung cancer
by Piotr Pawlik & Kristiana Grigoriadis & Abigail Bunkum & Helena Coggan & Alexander M. Frankell & Carlos Martinez-Ruiz & Takahiro Karasaki & Ariana Huebner & Andrew Rowan & Jasmin Fisher & Allan Hackshaw & Charles Swanton & Simone Zaccaria & Nicholas McGranahan - 198-207 Transient APC/C inactivation by mTOR boosts glycolysis during cell cycle entry
by Debasish Paul & Derek L. Bolhuis & Hualong Yan & Sudipto Das & Xia Xu & Christina C. Abbate & Lisa M. M. Jenkins & Michael J. Emanuele & Thorkell Andresson & Jing Huang & John G. Albeck & Nicholas G. Brown & Steven D. Cappell - 208-217 Establishment of chromatin architecture interplays with embryo hypertranscription
by Guang Yu & Kai Xu & Weikun Xia & Ke Zhang & Qianhua Xu & Lijia Li & Zili Lin & Ling Liu & Bofeng Liu & Zhenhai Du & Xia Chen & Qiang Fan & Fangnong Lai & Wenying Wang & Lijuan Wang & Feng Kong & Chao Wang & Haiqiang Dai & Huili Wang & Wei Xie - 218-226 A missing enzyme-rescue metabolite as cause of a rare skeletal dysplasia
by Jean Jacobs & Hristiana Lyubenova & Sven Potelle & Johannes Kopp & Isabelle Gerin & Wing Lee Chan & Miguel Rodriguez de los Santos & Wiebke Hülsemann & Martin A. Mensah & Valérie Cormier-Daire & Marieke Joosten & Hennie T. Bruggenwirth & Kyra E. Stuurman & Valancy Miranda & Philippe M. Campeau & Lars Wittler & Julie Graff & Stefan Mundlos & Daniel M. Ibrahim & Emile Van Schaftingen & Björn Fischer-Zirnsak & Uwe Kornak & Nadja Ehmke & Guido T. Bommer - 227-235 Pre-rRNA spatial distribution and functional organization of the nucleolus
by Yu-Hang Pan & Lin Shan & Yu-Yao Zhang & Zheng-Hu Yang & Yuan Zhang & Shi-Meng Cao & Xiao-Qi Liu & Jun Zhang & Li Yang & Ling-Ling Chen - 236-245 Molecular mechanism of ultrafast transport by plasma membrane Ca2+-ATPases
by Deivanayagabarathy Vinayagam & Oleg Sitsel & Uwe Schulte & Cristina E. Constantin & Wout Oosterheert & Daniel Prumbaum & Gerd Zolles & Bernd Fakler & Stefan Raunser - 247-250 How money, politics and technology are redefining the PhD experience in 2025
by Linda Nordling - 252-252 Little urchins, mischievous molluscs: my life as a sea champion
by Jack Leeming
September 2025, Volume 645, Issue 8082
- 10-10 Author Correction: PPP2R1A mutations portend improved survival after cancer immunotherapy
by Yibo Dai & Anne Knisely & Mitsutake Yano & Minghao Dang & Emily M. Hinchcliff & Sanghoon Lee & Annalyn Welp & Manoj Chelvanambi & Matthew Lastrapes & Heng Liu & Zhe Yuan & Chen Wang & Hao Nie & Stephanie Jean & Luis J. Montaner & Jiakai Hou & Ami Patel & Shrina Patel & Bryan Fellman & Ying Yuan & Baohua Sun & Renganayaki Krishna Pandurengan & Edwin Roger Parra Cuentas & Joseph Celestino & Yan Liu & Jinsong Liu & R. Tyler Hillman & Shannon N. Westin & Anil K. Sood & Pamela T. Soliman & Aaron Shafer & Larissa A. Meyer & David M. Gershenson & David Vining & Dhakshinamoorthy Ganeshan & Karen Lu & Jennifer A. Wargo & Weiyi Peng & Rugang Zhang & Linghua Wang & Amir A. Jazaeri - 11-11 Author Correction: A broad-spectrum lasso peptide antibiotic targeting the bacterial ribosome
by Manoj Jangra & Dmitrii Y. Travin & Elena V. Aleksandrova & Manpreet Kaur & Lena Darwish & Kalinka Koteva & Dorota Klepacki & Wenliang Wang & Maya Tiffany & Akosiererem Sokaribo & Xuefei Chen & Zixin Deng & Meifeng Tao & Brian K. Coombes & Nora Vázquez-Laslop & Yury S. Polikanov & Alexander S. Mankin & Gerard D. Wright - 12-12 Publisher Correction: In situ light-field imaging of octopus locomotion reveals simplified control
by Kakani Katija & Christine L. Huffard & Paul L. D. Roberts & Joost Daniels & Jon Erickson & Denis Klimov & Henry A. Ruhl & Alana D. Sherman - 13-13 Editorial Expression of Concern: Recovery of learning and memory is associated with chromatin remodelling
by Andre Fischer & Farahnaz Sananbenesi & Xinyu Wang & Matthew Dobbin & Li-Huei Tsai - 823-823 Universities under fire must harness more of the financial value they create
by Yasheng Huang - 824-824 How can universities train the skilled workers of tomorrow?
by Roseanne Warren - 827-828 LIGO is 10 years old: black-hole breakthroughs will ‘only get better’
by Davide Castelvecchi - 829-829 Mysterious changes near Earth’s core revealed by satellites in space
by Alexandra Witze - 830-831 ‘Revolutionary’ AI tools rescue old weather data to improve climate models
by Davide Castelvecchi - 831-832 Weird ‘time crystals’ are made visible at last
by Elizabeth Gibney - 832-833 When AI rejects your grant proposal: algorithms are helping to make funding decisions
by David Adam - 833-834 Trump team disbands controversial US climate panel
by Jeff Tollefson - 834-834 Dinosaur egg dated directly for the first time
by Mohana Basu - 836-839 The great university shake-up: four charts show how global higher education is changing
by Dan Garisto - 840-842 The mini placentas and ovaries revealing the basics of women’s health
by Cassandra Willyard - 843-844 Fighting climate change takes more than data — it needs wonder, love and hope
by Raya Muttarak - 845-847 What drove the rise of civilizations? A decades-long quest points to warfare
by Laura Spinney - 847-847 Reviving the past and designing the future: Books in brief
by Andrew Robinson - 849-851 How universities came to be — and why they are in trouble now
by Philip G. Altbach - 852-855 Universities must move with the times: how six scholars tackle AI, mental health and more
by Ya-Qin Zhang & Ramesh Jagannathan & Denise Pires de Carvalho & Lorna Dougan & Bala Ganesh Pichamuthu & Sibonokuhle Ndlovu - 856-856 US investment in African food systems will have global benefits
by Christopher B. Barrett & Mario Herrero & Appolinaire Djikeng & Jessica Fanzo - 856-856 Long-standing marine reserves need continued support
by Diego K. Kersting & Alfonso A. Ramos-Esplá & José Templado & Enric Sala - 856-856 Combat the human-made causes of Spain’s wildfires
by Jesús Miguel Avilés - 856-856 China’s private higher-education sector is at a turning point
by Yanchao Feng & Shilei Hu - 857-858 Electrostatic-based transfer keeps 2D materials ultra-clean
by Wanqing Meng & Lain-Jong Li - 858-859 How the pelvis evolved to enable human bipedalism
by Camille Berthelot - 860-861 The perplexing body plan of arrow worms decoded
by Thomas D. Lewin & Yi-Jyun Luo - 861-862 Robotic system takes chemistry into hyperspace
by William E. Robinson - 862-864 Oestrogen defends against kidney damage caused by iron-dependent cell death
by Tom Vanden Berghe - 864-865 Head start: fossil clues about how bodies evolved from two-fold to five-fold symmetry
by Gregory A. Wray - 866-867 Exercise improves survival of some people with colon cancer, clinical trial shows
by Doris S. M. Chan & Marc J. Gunter - 869-876 The geoeconomic turn in decarbonization
by Jonas Meckling - 877-885 The Biodiversity Cell Atlas: mapping the tree of life at cellular resolution
by Arnau Sebé-Pedrós & Amos Tanay & Mara K. N. Lawniczak & Detlev Arendt & Stein Aerts & John Archibald & Maria Ina Arnone & Mark Blaxter & Phillip Cleves & Susana M. Coelho & Mafalda Dias & Casey Dunn & Anamaria Elek & Jonathan Frazer & Toni Gabaldón & Jesse Gillis & Xavier Grau-Bové & Roderic Guigó & Oliver Hobert & Jaime Huerta-Cepas & Manuel Irimia & Allon Klein & Harris Lewin & Christopher J. Lowe & Heather Marlow & Jacob M. Musser & László G. Nagy & Sebastián R. Najle & Lior Pachter & Sadye Paez & Irene Papatheodorou & Michael J. Passalacqua & Nikolaus Rajewsky & Seung Y. Rhee & Thomas A. Richards & Tatjana Sauka-Spengler & Lauren M. Saunders & Eve Seuntjens & Jordi Solana & Yuyao Song & Ulrich Technau & Bo Wang - 886-892 Analogue speech recognition based on physical computing
by Mohamadreza Zolfagharinejad & Julian Büchel & Lorenzo Cassola & Sachin Kinge & Ghazi Sarwat Syed & Abu Sebastian & Wilfred G. Wiel - 893-899 Atomic-scale imaging of frequency-dependent phonon anisotropy
by Xingxu Yan & Paul M. Zeiger & Yifeng Huang & Haoying Sun & Jie Li & Chaitanya A. Gadre & Hongbin Yang & Ri He & Toshihiro Aoki & Zhicheng Zhong & Yuefeng Nie & Ruqian Wu & Ján Rusz & Xiaoqing Pan - 900-905 Observing differential spin currents by resonant inelastic X-ray scattering
by Yanhong Gu & Joseph Barker & Jiemin Li & Takashi Kikkawa & Fernando Camino & Kim Kisslinger & John Sinsheimer & Lukas Lienhard & Jackson J. Bauer & Caroline A. Ross & Dmitri N. Basov & Eiji Saitoh & Jonathan Pelliciari & Gerrit E. W. Bauer & Valentina Bisogni - 906-914 Electrostatic-repulsion-based transfer of van der Waals materials
by Xudong Zheng & Jiangtao Wang & Jianfeng Jiang & Tianyi Zhang & Jiadi Zhu & Tong Dang & Peng Wu & Ang-Yu Lu & Ding-Rui Chen & Tilo H. Yang & Xinyuan Zhang & Kenan Zhang & Kyung Yeol Ma & Zhien Wang & Aijia Yao & Haomin Liu & Yi Wan & Ya-Ping Hsieh & Vladimir Bulović & Tomás Palacios & Jing Kong - 915-921 Stabilizing effect of amino acids on protein and colloidal dispersions
by Ting Mao & Xufeng Xu & Pamina M. Winkler & Cécilia Siri & Ekaterina Poliukhina & Paulo Jacob Silva & Nan Xu & Yu Hu & Karim Al Zahabi & Rémi Polla & Zhi Luo & Quy Ong & Alfredo Alexander-Katz & Francesco Stellacci - 922-931 Robot-assisted mapping of chemical reaction hyperspaces and networks
by Yankai Jia & Rafał Frydrych & Yaroslav I. Sobolev & Wai-Shing Wong & Bibek Prajapati & Daniel Matuszczyk & Yasemin Bilgi & Louis Gadina & Juan Carlos Ahumada & Galymzhan Moldagulov & Namhun Kim & Eric S. Larsen & Maxence Deschamps & Yanqiu Jiang & Bartosz A. Grzybowski - 932-938 Catalytic enantioselective synthesis of alkylidenecyclopropanes
by Jonathan C. Golec & Dong-Hang Tan & Ken Yamazaki & Eveline H. Tiekink & Kirsten E. Christensen & Trevor A. Hamlin & Darren J. Dixon - 939-945 Volcanic crisis reveals coupled magma system at Santorini and Kolumbo
by Marius P. Isken & Jens Karstens & Paraskevi Nomikou & Michelle Maree Parks & Vincent Drouin & Eleonora Rivalta & Gareth J. Crutchley & Mahmud Haghshenas Haghighi & Emilie E. E. Hooft & Simone Cesca & Thomas R. Walter & Sebastian Hainzl & Joachim Saul & Dimitris Anastasiou & Kostas Raptakis & Nikolai M. Shapiro & Jannes Münchmeyer & Quentin Higueret & Jean Soubestre & Florent Brenguier & Rebeckah S. Hufstetler & Kaisa R. Autumn & Maria Tsakiri & Dietrich Lange & Heidrun Kopp & Morelia Urlaub & María Blanch Jover & Jonas Preine & Christian Hübscher & Mahdi Motagh & Daniel Müller & Torsten Dahm & Christian Berndt - 946-951 Stronger El Niños reduce tropical forest arthropod diversity and function
by Adam C. Sharp & Michael J. W. Boyle & Timothy C. Bonebrake & Yirong Guo & Roger L. Kitching & Nigel E. Stork & Xiaoyi Zeng & Louise A. Ashton - 952-963 The evolution of hominin bipedalism in two steps
by Gayani Senevirathne & Serena C. Fernandopulle & Daniel Richard & Stephanie L. Baumgart & Anika Liv Christensen & Matteo Fabbri & Jakob Höppner & Harald Jüppner & Peishu Li & Vivien Bothe & Nadia Fröbisch & Ian Simcock & Owen J. Arthurs & Alistair Calder & Naomi Freilich & Niamh C. Nowlan & Ian A. Glass & April Craft & Terence D. Capellini - 964-973 The genomic origin of the unique chaetognath body plan
by Laura Piovani & Daria Gavriouchkina & Elise Parey & Luke A. Sarre & Katja T. C. A. Peijnenburg & José María Martín-Durán & Daniel S. Rokhsar & Noriyuki Satoh & Alex Mendoza & Taichiro Goto & Ferdinand Marlétaz - 974-980 Replay and representation dynamics in the hippocampus of freely flying bats
by Angelo Forli & Wudi Fan & Kevin K. Qi & Michael M. Yartsev - 981-990 A hypothalamic circuit that modulates feeding and parenting behaviours
by Ivan C. Alcantara & Chia Li & Claire Gao & Shakira Rodriguez González & Laura E. Mickelsen & Brian N. Papas & Abigail I. Goldschmidt & Isabel M. Cohen & Christopher M. Mazzone & Isabel Araujo Salgado & Ramón A. Piñol & Cuiying Xiao & Eva O. Karolczak & Jian-Liang Li & Guohong Cui & Marc L. Reitman & Michael J. Krashes - 991-1001 Inter-brain neural dynamics in biological and artificial intelligence systems
by Xingjian Zhang & Nguyen Phi & Qin Li & Ryan Gorzek & Niklas Zwingenberger & Shan Huang & John L. Zhou & Lyle Kingsbury & Tara Raam & Ye Emily Wu & Don Wei & Jonathan C. Kao & Weizhe Hong - 1002-1010 Commensal yeast promotes Salmonella Typhimurium virulence
by Kanchan Jaswal & Olivia A. Todd & Roberto C. Flores Audelo & William Santus & Saikat Paul & Ciera M. Duffy & Edward T. Eshoo & Manmeet Singh & Jian Miao & David M. Underhill & Brian M. Peters & Judith Behnsen - 1011-1019 Multiple oestradiol functions inhibit ferroptosis and acute kidney injury
by Wulf Tonnus & Francesca Maremonti & Shubhangi Gavali & Marlena Nastassja Schlecht & Florian Gembardt & Alexia Belavgeni & Nadja Leinung & Karolin Flade & Natalie Bethe & Sofia Traikov & Anne Haag & Danny Schilling & Sider Penkov & Melodie Mallais & Christine Gaillet & Claudia Meyer & Melika Katebi & Anushka Ray & Louisa M. S. Gerhardt & Anne Brucker & Jorunn Naila Becker & Mirela Tmava & Lisa Schlicker & Almut Schulze & Nina Himmerkus & Andrej Shevchenko & Mirko Peitzsch & Uladzimir Barayeu & Sonia Nasi & Juliane Putz & Kenneth S. Korach & Joel Neugarten & Ladan Golestaneh & Christian Hugo & Jan Ulrich Becker & Joel M. Weinberg & Svenja Lorenz & Bettina Proneth & Marcus Conrad & Eckhard Wolf & Bernd Plietker & Raphaël Rodriguez & Derek A. Pratt & Tobias P. Dick & Maria Fedorova & Stefan R. Bornstein & Andreas Linkermann - 1020-1028 Determinants of successful AAV-vectored delivery of HIV-1 bNAbs in early life
by Amir Ardeshir & Daniel O’Hagan & Isha Mehta & Siddhartha Shandilya & Lincoln L. J. Hopkins & Lourdes Adamson & Marcelo J. Kuroda & Patricia A. Hahn & Lucas A. B. da Costa & Sebastian P. Fuchs & Jose M. Martinez-Navio & Matthew R. Gardner & Koen K. A. Van Rompay & Diogo M. Magnani & Jeffrey D. Lifson & Guangping Gao & Michael Farzan & Ronald C. Desrosiers & Jishnu Das & Mauricio A. Martins - 1029-1038 Genetic suppression features ABHD18 as a Barth syndrome therapeutic target
by Sanna N. Masud & Anchal Srivastava & Patricia Mero & Victoria Saba Echezarreta & Eve Anderson & Lennard Buren & Jiarun Wei & David Thomson Taylor & Adrian Granda Farias & Nicholas Mikolajewicz & Angela Shaw & Brandon M. Murareanu & Michelle Lohbihler & Olivia Sniezek Carney & Simon Heeringen & Linda Clijsters & Olga Sizova & Jeroen Ameijde & Freya Nye & Andrea Habsid & Lucy Nedyalkova & Laura McDonald & Craig Simpson & Leanne Wybenga-Groot & Kevin R. Brown & Nhi Nho & Radu M. Suciu & Katherine Chan & Amy H. Y. Tong & Frédéric M. Vaz & Bastiaan Evers & Robert Lesurf & Tanya Papaz & Lauryl M. J. Nutter & Stephanie Protze & Maximilian Billmann & Michael Costanzo & Brenda J. Andrews & Chad L. Myers & Seema Mital & Hilary Vernon & Thijn R. Brummelkamp & Charles Boone & Ian C. Scott & Micah J. Niphakis & Douglas Strathdee & Sebastian M. B. Nijman & Vincent A. Blomen & Jason Moffat - 1039-1050 Expanding the cytokine receptor alphabet reprograms T cells into diverse states
by Yang Zhao & Masato Ogishi & Aastha Pal & Leon L. Su & Pingdong Tao & Hua Jiang & Grayson E. Rodriguez & Xiaojing Chen & Qinli Sun & Lea Wenting Rysavy & Sam Limsuwannarot & Deepa Waghray & Anusha Kalbasi & K. Christopher Garcia - 1051-1059 NNMT inhibition in cancer-associated fibroblasts restores antitumour immunity
by Janna Heide & Agnes J. Bilecz & Samarjit Patnaik & Maria Francesca Allega & Leonhard Donle & Kaiting Yang & Ethan Teich & Yan Li & Qiaoshan Lin & Ke Kong & Li Liu & Tae Gyun Yang & Ken Chih-Chien Cheng & Jonathan H. Shrimp & Quinlin M. Hanson & Min Shen & Hongmao Sun & Hardik Shah & Lisa Schweizer & Katarzyna Zawieracz & Andrea Olland & Andre White & Robert K. Suto & Razzaq Alhunayan & Medine Taşdemir & Noa Longman & Hua Liang & Matthias Mann & Gordon M. Stott & Matthew D. Hall & Simon Schwörer & Ralph R. Weichselbaum & András Piffkó & Ernst Lengyel - 1060-1070 Elementary 3D organization of active and silenced E. coli genome
by Alexey A. Gavrilov & Ilya Shamovsky & Irina Zhegalova & Sergey Proshkin & Yosef Shamovsky & Grigory Evko & Vitaly Epshtein & Aviram Rasouly & Anna Blavatnik & Sudipta Lahiri & Eli Rothenberg & Sergey V. Razin & Evgeny Nudler - 1071-1080 NASP modulates histone turnover to drive PARP inhibitor resistance
by Sarah C. Moser & Anna Khalizieva & Josef Roehsner & Elisabeth Pottendorfer & Milo L. Kaptein & Giulia Ricci & Vivek Bhardwaj & Onno B. Bleijerveld & Liesbeth Hoekman & Ingrid Heijden & Simone Sanzo & Alexander Fish & Aleksandra Chikunova & Judith H. I. Haarhuis & Roel Oldenkamp & Luisa Robbez-Masson & Justin Sprengers & Daniel J. Vis & Lodewyk F. A. Wessels & Marieke Ven & Stephen J. Pettitt & Andrew N. J. Tutt & Christopher J. Lord & Benjamin D. Rowland & Moritz Völker-Albert & Francesca Mattiroli & Thijn R. Brummelkamp & Abdelghani Mazouzi & Jos Jonkers - 1081-1089 Structural basis of fast N-type inactivation in Kv channels
by Xiao-Feng Tan & Ana I. Fernández-Mariño & Yan Li & Tsg-Hui Chang & Kenton J. Swartz - 1091-1093 No lectures, exams, essays: inside a twenty-first-century university
by Anna McKie - 1094-1096 Real-time molecular recorders expose the inner lives of cells
by Elie Dolgin - 1098-1098 I deeply scan timber to reduce wasting this precious resource
by Stav Dimitropoulos
September 2025, Volume 645, Issue 8081
- 2-2 New Hope in Alzheimer’s Research
by Lauren Gravitz - 3-5 Can Diet and Exercise Really Prevent Alzheimer’s?
by Sara Harrison - 4-4 Author Correction: Macrophages excite muscle spindles with glutamate to bolster locomotion
by Yuyang Yan & Nuria Antolin & Luming Zhou & Luyang Xu & Irene Lisa Vargas & Carlos Daniel Gomez & Guiping Kong & Ilaria Palmisano & Yi Yang & Jessica Chadwick & Franziska Müller & Anthony M. J. Bull & Cristina Lo Celso & Guido Primiano & Serenella Servidei & Jean François Perrier & Carmelo Bellardita & Simone Giovanni - 5-5 Author Correction: Disease-associated astrocyte epigenetic memory promotes CNS pathology
by Hong-Gyun Lee & Joseph M. Rone & Zhaorong Li & Camilo Faust Akl & Seung Won Shin & Joon-Hyuk Lee & Lucas E. Flausino & Florian Pernin & Chun-Cheih Chao & Kilian L. Kleemann & Lena Srun & Tomer Illouz & Federico Giovannoni & Marc Charabati & Liliana M. Sanmarco & Jessica E. Kenison & Gavin Piester & Stephanie E. J. Zandee & Jack P. Antel & Veit Rothhammer & Michael A. Wheeler & Alexandre Prat & Iain C. Clark & Francisco J. Quintana - 6-6 Author Correction: Complex genetic variation in nearly complete human genomes
by Glennis A. Logsdon & Peter Ebert & Peter A. Audano & Mark Loftus & David Porubsky & Jana Ebler & Feyza Yilmaz & Pille Hallast & Timofey Prodanov & DongAhn Yoo & Carolyn A. Paisie & William T. Harvey & Xuefang Zhao & Gianni V. Martino & Mir Henglin & Katherine M. Munson & Keon Rabbani & Chen-Shan Chin & Bida Gu & Hufsah Ashraf & Stephan Scholz & Olanrewaju Austine-Orimoloye & Parithi Balachandran & Marc Jan Bonder & Haoyu Cheng & Zechen Chong & Jonathan Crabtree & Mark Gerstein & Lisbeth A. Guethlein & Patrick Hasenfeld & Glenn Hickey & Kendra Hoekzema & Sarah E. Hunt & Matthew Jensen & Yunzhe Jiang & Sergey Koren & Youngjun Kwon & Chong Li & Heng Li & Jiaqi Li & Paul J. Norman & Keisuke K. Oshima & Benedict Paten & Adam M. Phillippy & Nicholas R. Pollock & Tobias Rausch & Mikko Rautiainen & Yuwei Song & Arda Söylev & Arvis Sulovari & Likhitha Surapaneni & Vasiliki Tsapalou & Weichen Zhou & Ying Zhou & Qihui Zhu & Michael C. Zody & Ryan E. Mills & Scott E. Devine & Xinghua Shi & Michael E. Talkowski & Mark J. P. Chaisson & Alexander T. Dilthey & Miriam K. Konkel & Jan O. Korbel & Charles Lee & Christine R. Beck & Evan E. Eichler & Tobias Marschall - 6-9 Alzheimer’s Drugs Are Finally Tackling the Disease Itself. Here’s How
by Esther Landhuis - 7-7 Author Correction: Endophilin marks and controls a clathrin-independent endocytic pathway
by Emmanuel Boucrot & Antonio P. A. Ferreira & Leonardo Almeida-Souza & Sylvain Debard & Yvonne Vallis & Gillian Howard & Laetitia Bertot & Nathalie Sauvonnet & Harvey T. McMahon - 8-8 Author Correction: Dual neuromodulatory dynamics underlie birdsong learning
by Jiaxuan Qi & Drew C. Schreiner & Miles Martinez & John Pearson & Richard Mooney - 9-9 Publisher Correction: Multiple oestradiol functions inhibit ferroptosis and acute kidney injury
by Wulf Tonnus & Francesca Maremonti & Shubhangi Gavali & Marlena Nastassja Schlecht & Florian Gembardt & Alexia Belavgeni & Nadja Leinung & Karolin Flade & Natalie Bethe & Sofia Traikov & Anne Haag & Danny Schilling & Sider Penkov & Melodie Mallais & Christine Gaillet & Claudia Meyer & Melika Katebi & Anushka Ray & Louisa M. S. Gerhardt & Anne Brucker & Jorunn Naila Becker & Mirela Tmava & Lisa Schlicker & Almut Schulze & Nina Himmerkus & Andrej Shevchenko & Mirko Peitzsch & Uladzimir Barayeu & Sonia Nasi & Juliane Putz & Kenneth S. Korach & Joel Neugarten & Ladan Golestaneh & Christian Hugo & Jan Ulrich Becker & Joel M. Weinberg & Svenja Lorenz & Bettina Proneth & Marcus Conrad & Eckhard Wolf & Bernd Plietker & Raphaël Rodriguez & Derek A. Pratt & Tobias P. Dick & Maria Fedorova & Stefan R. Bornstein & Andreas Linkermann - 10-12 Controversial New Alzheimer’s Drugs Offer Hope—But at a High Cost
by Liz Seegert - 13-15 The Vexing Promise of New Blood Tests for Alzheimer’s
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