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Content
December 2026, Volume 17, Issue 1
- 1-19 Monitoring rapid degradation of NANOG reveals UTP15 maintains pluripotency by regulating nascent transcripts
by Mingqiang Deng & Dongmei He & Xiwei Wang & Yuting Yuan & Lishen Wang & Yanlin Hou & Qiuyue Zhu & Chuanman Zhou & Zhibiao Mai & Yulong Zhang & Zhengwen Nie & Yuling Song & Qiongfang Wu & Luyao Pan & Bei Dong & Zhi Xiong & Duo Li & Dongjun Liu & Jinxin Xu & Dajiang Qin & Hui Zheng & Yu Zhao & Peng Tang & Jinkai Wang & Cristin Print & Ralf Jauch & Wensheng Zhang & Guangming Wu & Xichen Bao
- 1-19 AI-driven decoding of naturalistic behaviors enables tailored detection of depressive-like behavior in mice
by Hyeonsik Oh & Sian Choi & Jinsu Lee & Heeyoung Lee & Jongpil Shin & Seungkyu Son & Bobae Hyeon & Won Do Heo
- 1-19 Scenario-adaptive hierarchical optimisation framework for design in hybrid energy storage systems
by Jiacheng Guo & Hao Wu & Tao Ma & Rongxin Yin & Yuekuan Zhou & Ji Li & Jinyue Yan & Jinqing Peng
- 1-19 Aberrant cytoplasmic localization of MLH1 characterizes a cell population that seeds breast cancer recurrence
by Aloran Mazumder & Jerry Dewitt & Elena Oropeza & Nindo Punturi & Daniel Lozano & Megha Raghunathan & Jonathan Piscitelli & Elham Sajjadi & Elena GueriniRocco & Konstantinos Venetis & Mariia Ivanova & Eltjona Mane & Marianna Dercole & Alberto Concardi & Nicola Fusco & Carol Manhart & Matthew Bainbridge & Svasti Haricharan
- 1-19 Meta-unstable mRNAs in activated CD8+ T cells are defined by interlinked AU-rich elements and m6A mRNA methylation
by Paulo A. Gameiro & Iosifina P. Foskolou & Yumna A. Butt & Aniek A. M. Martens & Klara Kuret Hodnik & Igor Ruiz de los Mozos & Nordin D. Zandhuis & Žan Hozjan & Veronica M. Kot & Rupert Faraway & Michiel Vermeulen & Monika C. Wolkers & Randall S. Johnson & Jernej Ule
- 1-19 USP16 S-nitrosylation aggravates coronary microembolization-induced myocardial injury via repressing KDM1A-mediated glutathione homeostasis
by Qiang Su & Jiao-Qin Qin & Yuan Huang & Ri-Xin Dai & Qing-Yun Wu & Li-Rong Mo & Qiang Wu & Wan-Zhong Huang & Hua-Feng Yang & Yang-Chun Liu & Di-Guang Pan
- 1-19 METTL3 safeguards cell identity and epigenome of human trophoblast stem cells
by Haifeng Fu & Chunxiao Chen & Yunying Huang & Weiyu Zhang & Shilong Li & For-Fan Chan & Ling Xu & Degong Ruan & Xiangyu Ouyang & Liyang Ma & Zhen Feng & Qingqing Zhang & Chunyan Wang & Dai Heng & Kexin Yao & Asif Javed & Chun-Ming Wong & Yin Lau Lee & William Shu Biu Yeung & Baofa Sun & Pentao Liu
- 1-19 Hippocampal-prefrontal orchestration supports higher-order learning for creative ideation
by Ze Zhang & Ziyi Li & Rui Ding & Guowei Wu & Xingxu Xie & Jiaqi Wu & Shaozheng Qin & Jing Luo
- 1-19 Targeting SPAK suppresses progression and averts an immune exhaustive microenvironment in hepatocellular carcinoma
by Yonglong Pan & Chenglong Zeng & Yi He & Ruizhi Chang & Jingjing Wu & Chaoyi Yuan & Haisen Li & Chen Su & Mengzhen Han & Pengcheng Li & Xinxin Li & Hongwei Zhang & Furong Liu & Huifang Liang & Zifu Li & Mi Wu & Limin Xia & Jianfeng Liu & Xiaoping Chen & Wanguang Zhang & Bixiang Zhang & Ze-yang Ding
- 1-19 Multi-center multi-omics integration predicts individualized prognosis in medullary thyroid carcinoma
by Yan Zhou & Yingrui Wang & Xiao Shi & Jiatong Wang & Zelin Zang & Likun Zhang & Zhiqiang Gui & Xue Cai & Pingping Hu & Jiaxi Wang & Hanqing Liu & Zhihong Wang & Haixia Guan & Xiaohong Wu & Cenkai Shen & Yi He & Mo Li & Hao Zhang & Jianbiao Wang & Yijun Wu & Chuang Chen & Yi Zhu & Yaoting Sun & Zhiyan Liu & Yu Wang & Tiannan Guo
- 1-19 USP10 promotes glioma stem cell maintenance and glioblastoma growth by antagonizing DTX3L-mediated SATB2 ubiquitination
by Mengyue Guo & Wenlong Luo & Peng Ling & Hong Lei & Lihua Li & Chao Duan & Zhen Xue & Min Zhang & Xiaoyan Zhang & Wendai Bao & Wenchao Zhou & Jianghong Man & Suojun Zhang & Kai Shu & Jun Qin & Xiuxing Wang & Zhiqiang Dong & Weiwei Tao
- 1-19 Ubiquitination by HRD1 is essential for TLR3 trafficking and its innate immune signaling
by Lianfeng Zhao & Zinan He & Yao Sun & Mengqi Sun & Zheyi Liu & Zhangsen Zhou & Ling Qi & Yuan Luo & Yewei Ji & Tingbo Liang
- 1-19 The Health for Life in Singapore (HELIOS) Study: delivering precision medicine research for Asian populations
by Xiaoyan Wang & Theresia Mina & Nilanjana Sadhu & Pritesh R. Jain & Hong Kiat Ng & Dorrain Yanwen Low & Darwin Tay & Terry Yoke Yin Tong & Wee-Lin Choo & Liming Lim & Swat Kim Kerk & Guo Liang Low & Benjamin Chih Chiang Lam & Rinkoo Dalan & Gervais Wanseicheong & Yik Weng Yew & Rob M. van Dam & Ee-J Leow & Soren Brage & Gregory A. Michelotti & Kari E. Wong & Patricia A. Sheridan & Pin Yan Low & Zhen Xuan Yeo & Nicolas Bertin & Claire Bellis & Maxime Hebrard & Pierre-Alexis Vincent Goy & Kostas Tsilidis & Harinakshi Sanikini & Xue Li Guan & Tock Han Lim & Lionel Lee & James D. Best & Patrick Tan & Paul Elliott & Eng Sing Lee & Jimmy Lee & Joanne Ngeow & Elio Riboli & Max Lam & Marie Loh & John C. Chambers
- 1-19 Neuronal feedback loop of the suprachiasmatic nucleus generates robust circadian rhythms
by Mohan Wang & Yusuke Tsuno & Yubo Peng & Md Tariqul Islam & Ayako Matsui & Takashi Maejima & Michihiro Mieda
- 1-19 A versatile platform for chemical engineering of exosomes empowered by ADP-ribosyl cyclases
by Lei Zhang & Srinivasarao Singireddi & Arshad J. Ansari & Guoyun Kao & Sunny H. Kim & Zeyu Zhang & Kaiyu Shen & Thuc Oanh Hoang & Xinping Duan & Qinqin Cheng & Tautis Skorka & Yong Zhang
- 1-19 Antibiotic contamination and antimicrobial resistance dynamics in the urban sewage microbiome in India
by Deepjyoti Paul & Daizee Talukdar & Ramani Shyam Kapuganti & Vaishali Gupta & Lekshmi Narendrakumar & Pradipta Jana & Pawan Kumar & Jyoti Singh & Shalini Kumari & Chandana Basak & Kajal Kamboj & Susmita Bakshi & Shruti Lal & Subhash Tanwar & Roshan Kumar & Prabhakar Babele & Manish Bajpai & Yashwant Kumar & Ankur Mutreja & Sukhendu Mandal & Nitya Wadhwa & Sanjay K. Banerjee & Bhabatosh Das
- 1-19 Binimetinib and encorafenib for the treatment of advanced solid tumors with non-V600E BRAF mutations: results from the Phase II BEAVER trial
by April A. N. Rose & Jennifer Maxwell & Emmanuelle Rousselle & Chantel L. Mukonoweshuro & Islam E. Elkholi & Melody Riaud & Marco Biondini & Erica Cianfarano & Isabel Soria-Bretones & Chantal Tobin & Meghan McGuire & Rhoda W. Y. Law & Andrew J. Elia & Ben X. Wang & Ian King & Tong Zhang & Trevor J. Pugh & Zaid Saeed Kamil & Marcus Butler & Frances A. Shepherd & Natasha B. Leighl & Albiruni Abdul Razak & Aaron Hansen & Samuel D. Saibil & Philippe L. Bedard & Peter M. Siegel & Lillian L. Siu & David W. Cescon & Anna Spreafico
- 1-19 Arachidonic acid induces pyroptosis via a non-autophagic function of mitophagy and enhances immunotherapy in a PDAC model
by Tongjia Chu & Ziyu Liu & Huan Liu & Wentao Mu & Yao Zhi & Nan Sheng & Jian Zhang & Xinyu Peng & Shengnan Lv & Kehang Duan & Fengxiang Lou & Han Liu & Chuanlei Wang & Jianpeng Zhou & Xingyu Liu & Haocheng Yang & Yunzhi Liu & Jingtong Xu & Zhongqi Fan & Feng Wei
- 1-19 Loss of ALK4 promotes cancer progression through regulating TGF-β receptor N-glycosylation
by Manqi Zhang & Jian Chen & Mary C. Leupold & Jennifer Guo & Xiangfeng Shen & Carl A. Shirley & Christen A. Khella & Rushabh N. Mehta & Edward T. O’Brien & Michael L. Gatza & Gerard C. Blobe
- 1-19 6-Phosphogluconate dehydrogenase promotes mitochondrial fusion and immune suppression in tumor-associated monocytic suppressor cells
by Saeed Daneshmandi & Qi Yan & Eduardo Cortes Gomez & Jee Eun Choi & Eriko Katsuta & Ehsan Gharib & Prashant K. Singh & Richard M. Higashi & Andrew N. Lane & Teresa W-M. Fan & Jianmin Wang & Elizabeth A. Repasky & Philip L. McCarthy & Hemn Mohammadpour
- 1-19 Multi-faceted roles of β-arrestins in G protein-coupled receptor endocytosis
by Junke Liu & Li Xue & Magalie A. Ravier & Floriane Eshak & Francine C. Acher & Anne Goupil-Lamy & Marta Cimadevila & Julia Drube & Carsten Hoffmann & Asuka Inoue & Eric Trinquet & Elodie Dupuis & Laurent Prézeau & Jean-Philippe Pin & Philippe Rondard
- 1-19 Molecular basis of XPF-ERCC1 targeting to SLX4-dependent DNA repair pathways
by Junjie Feng & Peter R. Martin & Szymon Kowalski & Maxime Lecot & Nora B. Cronin & Teige Matthews-Palmer & Wojciech Niedzwiedz & Basil J. Greber
- 1-19 Tumor agnostic drug delivery with dynamic nanohydrogels
by Stephen N. Housley & Alisyn R. Bourque & Lilya V. Matyunina & Isabel A. Panicker & Elisa Schrader Echeverri & Marrissa Izykowicz & Olivia A. Herrmann & Sebinne Lee & Johana C. Arboleda & Vida Jamali & John F. McDonald & James E. Dahlman & M. G. Finn
- 1-19 Simultaneous and sensitive quantification of protein and low molecular weight persulfides, polysulfides and H2S in biological samples
by Jan Lj. Miljkovic & Nils Burger & Chak Shun Yu & Alexander H. Harkiss & Stefan Warrington & Stuart T. Caldwell & Scott A. Jones & Jordan J. Lee & Dunja Aksentijevic & Andrew M. James & Thomas Krieg & Richard C. Hartley & Michael P. Murphy
- 1-19 Mechanosensor-mediated Hsp70 phosphorylation orchestrates the landscape of the heat shock response
by Siddhi Omkar & Jake T. Kline & James H. Grissom & Diyun Sun & Richard J. Chi & Jared A. M. Bard & Luca Fornelli & Andrew W. Truman
- 1-19 Mechanism of RPA phosphocode priming and tuning by CDK1/WEE1 signaling circuit
by Poonam Roshan & Vikas Kaushik & Ayush Mistry & Abhinav Vayyeti & Aidan Antony & Riley Luebbers & Jaigeeth Deveryshetty & Edwin Antony & Sofia Origanti
- 1-19 Mechanism of trans-envelope bacterial polysaccharide secretion in Class-3 outer-membrane polysaccharide export (OPX) protein systems
by Abdelkader Mellouk & Kenny Ngo & Ahmad A. Kezzo & Cyrielle Martini & Tanos C. C. França & Steven R. Laplante & Salim T. Islam & Charles Calmettes
- 1-19 Integrative transcriptome-wide association analyses reveal PRKCG-linked GABAergic dysfunction in Fragile X-associated tremor/ataxia syndrome
by Yulin Jin & Yiqu Cao & Wenjing Ma & Ronghua Li & Yujing Li & Yunhee Kang & Jing Huang & Michael P. Epstein & Xiangxue Guo & Junghwa Lim & Natalia Rivera & Ying Zhou & Zhexing Wen & Emily G. Allen & Peng Jin
- 1-19 4R-tau seeding activity reveals molecular subtypes in progressive supranuclear palsy
by Ivan Martinez-Valbuena & Seojin Lee & Enrique Santamaria & Joaquín Fernández-Irigoyen & Shelley L. Forrest & Silvia Zampar & Jun Li & Hidetomo Tanaka & Blas Couto & Nikolai Gil D. Reyes & Syeda Hania Qamar & Ali M. Karakani & Ain Kim & Konstantin Senkevich & Ekaterina Rogaeva & Susan H. Fox & M. Carmela Tartaglia & Naomi P. Visanji & Martin Ingelsson & Tallulah Andrews & Anthony E. Lang & Gabor G. Kovacs
- 1-19 Intelectin-2 is a broad-spectrum antimicrobial lectin
by Amanda E. Dugan & Deepsing Syangtan & Eric B. Nonnecke & Rajeev S. Chorghade & Amanda L. Peiffer & Jenny J. Yao & Jessica Ille-Bunn & Dallis Sergio & Gleb Pishchany & Catherine Dhennezel & Hera Vlamakis & Sunhee Bae & Sheila Johnson & Chariesse Ellis & Soumi Ghosh & Jill W. Alty & Carolyn E. Barnes & Miri Krupkin & Gerardo Cárcamo-Oyarce & Katharina Ribbeck & Ramnik J. Xavier & Charles L. Bevins & Laura L. Kiessling
- 1-19 GBP2 condensates promote ferroptosis to sensitize anti-PD-L1 immunotherapy in melanoma
by Xin Liu & Shilin Fang & Xianghai Ren & Yuntian Hong & Jianchun Guo & Xiaoping Liu & Liping Gao & Haihang Nie & Yumei Ning & Meng Zhang & Fei Xu & Lan Liu & Jun Fang & Yu Pang & Qiu Zhao & Fan Wang & Haizhou Wang
- 1-19 A comprehensive N-glycoproteome atlas reveals tissue-specific glycan remodeling but non-random structural microheterogeneities
by Yongqi Wu & Muyao Yang & Yongchao Xu & Li Jia & Jun Li & Xiaohan Wang & Jiayu Zhao & Yinli Cai & Yiwen Zhang & Shisheng Sun
- 1-19 Quantitative optical nanoscopy of mitochondrial-derived vesicles in neurons classifies pre-peroxisomal and clearing organelles
by Giovanna Coceano & Jonatan Alvelid & Martina Damenti & Gabriella Ferretti & Johannes Mueller & Joanna Rorbach & Ilaria Testa
- 1-19 Microgliopathy as a primary mediator of neuronal death in models of Friedreich’s Ataxia
by Carla Pernaci & Avalon Johnson & Sydney Gillette & Anna S. Warden & Chad McCormick & Sammy Weiser-Novak & Gabriela Ramirez & Emily H. Broersma & Priyanka Mishra & Anusha Sivakumar & Stephanie Cherqui & Nicole G. Coufal
- 1-19 LncRNA CISTR-ACT regulates cell size in human and mouse by guiding FOSL2
by Katerina Kiriakopulos & Katty Soleimanpour & Brandon J. McMurray & Benjamin-Israel Moke & Jordan J. Chalmers & Milad Mokhtaridoost & Jeremy D. Newton & Taylor De Young & Kate Delfosse & Mai Ahmed & Cassandra J. Wong & Sigmar Stricker & Yun Li & Brian J. Nieman & Anne-Claude Gingras & Monica J. Justice & Julie L. Lefebvre & Philipp G. Maass
- 1-19 Co-condensation between transcription factor and cBAF selectively modulates chromatin remodeling and gene expression
by Xifu Ye & Lin Xu & Xuejiao Sun & Yanzhi Gai & Haixia Yang & Qiang Sun & Jiayi Song & Peiqi Huang & Qianru Zhou & Yaxu Li & Na Li & Jiali Jin & Yang Li & Wei Rao & Huasong Lu & Ping Wang & Chunmei Chang & Yi Lu
- 1-19 Major waves of H2A.Z incorporation during mouse oogenesis and preimplantation embryo development
by Madeleine Fosslie & Erkut Ilaslan & Trine Skuland & Michel Choudalakis & Mirra Søegaard & Jason Alexander Halliwell & Shaista Khan & Marie Indahl & Maria Vera-Rodriguez & Adeel Manaf & Annika Vera Geijer-Simpson & Rajikala Suganthan & Ingunn Jermstad & Knut Tomas Dalen & Ragnhild Eskeland & Elisabeth Kommisrud & Arne Klungland & Magnar Bjørås & Peter Fedorcsak & Gareth D. Greggains & Mika Zagrobelny & John Arne Dahl & Mads Lerdrup
- 1-19 High-fat diet disrupts a septal control on feeding to promote obesity in male mice
by Shaolei Jiang & Shishi Lai & Haiyang Jing & Xiaocong Wu & Fengling Li & Bo Chen & Jin Bao & Liping Wang & Gaowei Chen & Yingjie Zhu
- 1-19 Harnessing theta-gamma coupled brainwaves using ultrasound for spinal astrocyte revitalization and sustained neuropathic pain relief in mice
by Tien Thuy Phan & Sangyep Shin & Ho Jeong Kim & Keunhyung Lee & Tai-Young Kim & Jae-Hun Lee & Dong-Wook Kang & Hyunjin Shin & Hye Eun Lee & Nishani Jayanika Jayathilake & Minseok Koo & Hyungju Park & Hyun-Woo Kim & Yee Joon Kim & Ji Young Mun & Jinhyoung Park & Kyu Pil Lee & C. Justin Lee & Joo Min Park
- 1-19 The role of attention in multi attribute decision making
by Aaron L. Sampson & You-Ping Yang & Marius Usher & Dino J. Levy & Ernst Niebur & Veit Stuphorn
- 1-19 OTX2 inhibits human pluripotent stem cell reprogramming toward 8-cell-like and morula-like states
by Xi Kong & Nan Jiang & Shaowei Chen & Xingyou Zhang & An Huang & Li Hu & Simeng Yi & Shigang Yin & Jianhua Peng & Yong Jiang & Huangfan Xie & Bingqing Xie
- 1-19 Accumulation of Trehalose 6-Phosphate in Candidozyma auris results in Decreased Echinocandin Resistance and Tolerance
by Qingjuan Zhu & Sien Van de Velde & Stefanie Wijnants & Hans Carolus & Stef Jacobs & Dimitrios Sofras & Paul Vandecruys & Odessa Van Goethem & Regina Feil & Rudy Vergauwen & Wouter Van Genechten & Wim Van den Ende & Jeffrey M. Rybak & Uwe Himmelreich & John E. Lunn & Patrick Van Dijck
- 1-19 NSUN7 is a catalytically inactive RNA m5C methyltransferase essential for sperm flagellum assembly
by Jing Li & Wen-Yu Zhu & Zhen Wang & Yuan-Yuan Zhang & Min-Min Hua & Qing-Yun Liu & You-Jia Zhou & Xing-Yi Wu & Hao Li & Mo-Fang Liu & Ru-Juan Liu
- 1-19 Rapid culture-free diagnosis of clinical pathogens via integrated microfluidic-Raman micro-spectroscopy
by Yuetao Li & Jiabao Xu & Xiaofei Yi & Xiaobo Li & Yanjun Luo & Andrew Glidle & Phil Summersgill & Simon Allen & Tim Ryan & Xiaochen Liu & Wei Yu & Xiaobing Chu & Shiyu Chen & Qian Zhang & Xiaogang Xu & Xiaoting Hua & Qiwen Yang & Julien Reboud & Yunsong Yu & Wei E. Huang & Jonathan M. Cooper & Huabing Yin
- 1-19 Adgrg6/Gpr126 is required for compact wall integrity and establishing trabecular identity during cardiac trabeculation
by Swati Srivastava & Felix Gunawan & Silvia Vergarajauregui & Alessandra Gentile & Miriam Angeloni & Sarah C. Petersen & Stefan Günther & Fulvia Ferrazzi & Didier Y. R. Stainier & Felix B. Engel
- 1-19 Sprint interval exercise disrupts mitochondrial ultrastructure driving a unique mitochondrial stress response and remodelling in men
by J. Botella & E. Perri & N. J. Caruana & S. López-Calcerrada & M. Brischigliaro & N. A. Jamnick & V. Oorschot & N. J. Saner & J. Díaz-Lara & D. F. Taylor & A. Garnham & E. Fernández-Vizarra & C. Ugalde & G. Ramm & D. A. Stroud & M. Lazarou & D. J. Bishop
- 1-19 A Pseudomonas aeruginosa quorum-sensing inducer controls lung permeability in establishing chronic infection via EGFR
by Mingke Zheng & Jie Chen & Gege Qin & Ze Zhang & Di Zhai & Hefei Ruan & Tie Xia & Tongtao Yue & Yan Shi
- 1-19 Flexible computation of object motion and depth based on viewing geometry inferred from optic flow
by Zhe-Xin Xu & Jiayi Pang & Akiyuki Anzai & Gregory C. DeAngelis
- 1-19 Schisantherin A interacts with gut bacteria to stimulate adipose tissue thermogenesis in obese mice via a TGR5‒p-CREB‒STAT6 signaling pathway
by Xunjiang Wang & Xu Wang & Shenglan Yu & Luyao Huang & Qiongwen Xue & Xinru Yang & Zixuan Wang & Wenyuan Lin & Yaping Jiang & Ying Xu & Qi Liao & Lihua Jin & Zhengtao Wang & Feng Tao & Li Yang & Wendong Huang & Lili Ding
- 1-19 Therapeutic 6-thio-deoxyguanosine inhibits telomere elongation in cancer cells by inducing a non-productive stalled telomerase complex
by Samantha L. Sanford & Mareike Badstübner & Michael Gerber & William Mannherz & Noah Lampl & Rachel Dannenberg & Angela Hinchie & Matthew A. Schaich & Sua Myong & Mark Hedglin & Suneet Agarwal & Jonathan K. Alder & Michael D. Stone & Patricia L. Opresko
- 1-19 TIGIT disruption rescues the antitumor activity of low avidity TCR-engineered T cells by increasing TCR signal strength
by Martina Spiga & Alessia Potenza & Zulma Magnani & Stefano Beretta & Barbara Camisa & Laura Conte & Alessia Airaghi & Neda Mohammadi & Laura Perani & Claudio Doglioni & Maurilio Ponzoni & Francesca Sanvito & Chiara Balestrieri & Lucia Sergi Sergi & Oronza A. Botrugno & Giulio Giovannoni & Giovanni Tonon & Danilo Abbati & Chiara Iozzi & Maximilian Reichert & Hana Algul & Arianna Pocaterra & Martina Fiumara & Samuele Ferrari & Alessia Ugolini & Alice Grometto & Giulia Di Lullo & Giovanni Sitia & Giulio Belfiori & Maria Pia Protti & Renato Ostuni & Anna Mondino & Michele Reni & Stefano Crippa & Massimo Falconi & Luigi Naldini & Eliana Ruggiero & Chiara Bonini
- 1-19 Genetic and non-genetic factors distinctly shape the variation of the immune response in cattle
by Shifang Li & Françoise Myster & Célia Darimont & Lijing Tang & Justine Javaux & Rémy Sandor & Gabriel Costa Monteiro Moreira & José Luis Gualdron Duarte & Philippe Crepin & Marc Dive & Patrick Mayeres & Tom Druet & Mihai G. Netea & Michel Georges & Carole Charlier & Laurent Gillet
- 1-19 Calcium channel blockers increase the risk of aortic aneurysm and dissection
by Tianfeng Ma & Zeyu Cai & Xinming Xu & Long Cao & Ao Wang & Zhongshuang Zhang & Siting Zhang & Zhenkun Huang & Jingjing Luo & Sen Lin & Jiashu Ge & Xinhao Wang & Yi Fu & Fang Yu & Jing Zhou & Lixin Wang & Hongpeng Zhang & Xiang Gao & Wei Guo & Wei Kong
- 1-19 Mechanistic insights into PCBP1-driven unfolding of selected i-motif DNA at G1/S checkpoint
by Pallabi Sengupta & Natacha Gillet & Ikenna Obi & Nasim Sabouri
- 1-19 O-GlcNAcylation of AMFR stabilizes TSPAN4 to regulate migrasome formation for viral release
by Linghui Yu & Jiajia Li & Yiyang Han & Xiao Yang & Yu Fu & Weiyi Zhang & Yaming Jiu & Linling Cheng & Binbin Ding
- 1-19 Exercise-induced histone lactylation in monocyte-derived macrophages restores cardiac immune homeostasis and function in sepsis-induced cardiomyopathy
by Shuo Sun & Chaojie Lai & Chengchen Huang & Xinrong Ren & Tingyu Zhang & Juan Zou & Yiping Tong & Qingyan Zhou & Jiangting Lu & Zhida Shen & Wentao Chen & Ruilin Wang & Nikola Rabrenovic & Xingwu Wang & Boxuan Ma & Junbin Qian & Guosheng Fu & Min Shang
- 1-19 Hyperglycemia exacerbates osteoarthritis by impairing macrophage efferocytosis through modulation of CD11b lactylation
by Hao Zhou & Yong Xiao & Xinchen Xue & Jiuxiang Liu & Hongtao Xu & Jinwen Wang & Jinchun Zhou & Qiang Zuo & Wenwei Liang & Huanghe Song & Zhefeng Chen & Feng Liu & Xiao Li & Kai Shen & Weimin Fan
- 1-19 Synovial sarcoma reprograms transcription by GBAF activation of polycomb targets and loss of CBAF enhancers
by Jinxiu Li & Li Li & Kyllie Smith-Fry & Muhammad Zaki Fadlullah & Lara Carroll & Linda Morrison & Xinyi Ge & Mary L. Nelson & Lesley A. Hill & Yixuan Guo & George Davenport & Xiaoyang Zhang & Torsten O. Nielsen & Martin Hirst & T. Michael Underhill & Bradley R. Cairns & Kevin B. Jones
- 1-19 Injured epithelial cell states impact kidney allograft survival after T-cell-mediated rejection
by Anna Maria Pfefferkorn & Lorenz Jahn & Patrick T. Gauthier & Vera Anna Kulow & Johannes Roeles & Niklas Müller-Bötticher & Louisa M. S. Gerhardt & Janna Leiz & Sadia Sarfraz & Izabela Plumbom & Robert Greite & Svjetlana Lovric & Jaba Gamrekelashvili & Florian Limbourg & Jessica Schmitz & Jan Hinrich Bräsen & Irina Scheffner & Igor M. Sauer & Felix Aigner & Janine Altmüller & Thomas Conrad & Wilfried Gwinner & Naveed Ishaque & Michael Fähling & Kai M. Schmidt-Ott & Philip F. Halloran & Muhammad Imtiaz Ashraf & Christian Hinze
- 1-19 Genetic profiling of the circulating proteome in common diseases suggests causal proteins and improves risk prediction
by Qianying Ma & Yimin Cai & Chunyi He & Yanmin Li & Caibo Ning & Ming Zhang & Zequn Lu & Can Chen & Yue Zong & Feitong Wu & Meng Jin & Yongchang Wei & Xiangpan Li & Xiaojun Yang & Chaoqun Huang & Bin Li & Zhaocheng Ma & Ying Zhu & Xiaoping Miao & Jianbo Tian
- 1-19 Single-cell exon deletion profiling reveals splicing events that shape gene expression and cell state dynamics
by Bandana Kumari & Arun Prasath Damodaran & Wilfried M. Guiblet & Mei-Sheng Xiao & Amit K. Behera & Tyler A. On & Carl E. McIntosh & Maxwell Teszler & Chelsee Holloway & Sandra Le & Nikhil Parab & Yongmei Zhao & Michael Aregger & Thomas Gonatopoulos-Pournatzis
- 1-19 Phosphorylation of PA28γ by CK2 kinase facilitates HNSCC tumor formation and progression
by Silu Sun & Bing Zhong & Ying Wang & Zaiye Li & Yuchen Jiang & Ning Ji & Xiaodong Feng & Rui Liu & Xin Zeng & Xikun Zhou & Chunjie Li & Hang Zhao & Jing Li & Qianming Chen
- 1-19 Soft sonocapacitor with topologically integrated piezodielectric nanospheres enables wireless epidural closed-loop neuromodulation
by Zhidong Wei & Fei Jin & Tong Li & Lili Qian & Juan Ma & Fengling Liu & Weiying Zheng & Yu Wang & Siwei Zhang & Ye You & Zhang-Qi Feng & Ting Wang
- 1-19 Tissue-specific mutagenesis from endogenous guanine damage is suppressed by Polκ and DNA repair
by Yang Jiang & Moritz Przybilla & Linda Bakker & Foster C. Jacobs & Dylan Mckeon & Roxanne van der Sluijs & Koichi Sato & Juliëtte Wezenbeek & Joeri van Strien & Jeroen Willems & Alexander E. E. Verkennis & Jamie Barnett & Adrian Baez Ortega & Federico Abascal & Peter W. Villalta & Puck Knipscheer & Inigo Martincorena & Silvia Balbo & Juan Garaycoechea
- 1-20 Aged skin exacerbates experimental osteoarthritis via enhanced IL-36R signaling
by Dalin Chen & Chong Wang & Changsheng Yang & Qinwei Cheng & Liangyu Chen & Panpan Yang & Zilin Zou & Zining Wang & Honghao Li & Yun Xiao & Junfeng Wu & Ee Ke & Xiaogang Wang & Bin Huang & Xiaochun Bai & Kai Li
- 1-20 Rad51 determines pathway usage in post-replication repair
by Damon Meyer & Steven K. Gore & Jie Liu & Shannon J. Ceballos & Shih-Hsun Hung & Giordano Reginato & Maria I. Cano-Linares & Katarzyna H. Maslowska & Florencia Villafañez & Clare Fasching & Christopher Ede & Vincent Pagès & Felix Prado & Petr Cejka & Wolf-Dietrich Heyer
- 1-20 Agonist signaling drives neutrophil subpopulations to promote/inhibit colorectal cancer liver metastasis
by Zhuoqing Xu & Haoran Feng & Wenqing Feng & Yuchen Zhang & Jianting Huo & Zifeng Xu & Fangqian Chen & Han Gao & Zeping Lv & Wangyi Liu & Abudumaimaitijiang Tuersun & Suyue Yu & Wenchang Li & Yaping Zong & Xiaohui Shen & Xi Cheng & Jingkun Zhao & Aiguo Lu
- 1-20 A unified time-frequency foundation model for sleep decoding
by Weixuan Huang & Yan Wang & Hanrong Cheng & Wei Xu & Tingyue Li & Xiuwen Wu & Hui Xu & Pan Liao & Zaixu Cui & Qihong Zou & Jia-Hong Gao
- 1-20 Polypeptide sono-adjuvant for ultrasound-activatable regulation of innate immunity and cancer vaccination therapy
by Fangmin Chen & Huijuan Zhang & Shiqin Li & Siyuan Ren & Lujia Huang & Yu Guo & Yi Lai & Zhixiong Cai & Xiaolong Liu & Zhiai Xu & Haijun Yu
- 1-20 Temporal constraints on enhancer usage shape the regulation of limb gene transcription
by Raquel Rouco & Antonella Rauseo & Fabrice Darbellay & Guillaume Sapin & Olimpia Bompadre & Lucille Lopez-Delisle & Guillaume Andrey
- 1-20 SREBP1-mediated lipogenesis promotes dedifferentiation and senescence of vascular smooth muscle cells through epigenetic remodeling
by Bowen Li & Kaixiang Zhou & Anan Yin & Yonghong Liu & Xichen Wang & Yujia Cui & Fangfang Liu & Qiurong Liu & Hongjing Zheng & Zhiqiang Mu & Kun Chen & Yuanming Wu & Yaoming Chang & Junxiang Bao
- 1-20 Reconstructing the three-dimensional architecture of extrachromosomal DNA with ec3D
by Biswanath Chowdhury & Kaiyuan Zhu & Chaohui Li & Jessica Alsing & Jens Luebeck & Maria E. Stefanova & Owen S. Chapman & Katerina Kraft & Shu Zhang & Jun Yi Stanley Lim & Yipeng Xie & Yoon Jung Kim & Sihan Wu & Lukas Chavez & Guy Nir & Anton G. Henssen & Paul S. Mischel & Howard Y. Chang & Vineet Bafna
- 1-20 Synthetic rewriting technologies in mammalian cells
by Yuqi Wang & Yali Cui & Guang-Rong Zhao & Yi Wu & Ying-Jin Yuan
- 1-20 VIRGO2: an enhanced gene catalog of the vaginal microbiome provides insights into its functional and ecology complexity
by Michael T. France & Issac Chaudry & Lindsay Rutt & Melanie Quain & Breanna Shirtliff & Elias McComb & Amaury Maros & Madeline Alizadeh & Fatima A. Hussain & Michal A. Elovitz & David A. Relman & Anisur Rahman & Rebecca M. Brotman & Joan T. Price & Margaret P. Kassaro & Johanna B. Holm & Bing Ma & Jacques Ravel
- 1-20 Altered B cell activation contributes to the immunopathogenesis of childhood arthritis-associated uveitis
by Bethany R. Jebson & Benjamin Ingledow & Vicky Alexiou & Jakub Kubiak & Persephone Jenkins & Yuxuan Meng & Melissa Kartawinata & Restuadi Restuadi & Wei-Yu Lin & Chris Wallace & Colin J. Chu & Ameenat Lola Solebo & Lucy R. Wedderburn & Elizabeth C. Rosser
- 1-20 DOT1L activity limits transcription elongation velocity and favors RNAPII pausing to facilitate mutagenesis by AID
by Poorani Ganesh Subramani & Noé Seija & Jana Ridani & Jonathan Boulais & Paul A. Donnelly & Mélanie Provencher & Halil Bagci & Christian Poitras & Jean-François Côté & François Robert & Javier M. Di Noia
- 1-20 Examining public support for Ukraine’s defense against autocratic aggression
by Lukas Rudolph & Fabian Haggerty & Paul W. Thurner
- 1-20 Revealing heterogeneity and damage response in the adult human utricle
by Emilia Luca & Neke Ibeh & Ryosuke Yamamoto & Weisheng Liang & Dallas Bennett & Vincent Lin & Joseph Chen & Michael Lovett & Alain Dabdoub
- 1-20 Stress induces oxytocin-Gαi-dependent remodeling of astrocytes to shape neuronal response in the amygdala
by Angel Baudon & Valentin Grelot & Kai-Yi Wang & Ferdinand Althammer & Clémence Denis & Pierre Riché-Piotaix & Azmal Syed Ali & Yudong Yan & Fernando Castillo Díaz & Francesca Piacentini & Etienne Clauss Creusot & Volodya Hovhannisyan & Tim Schubert & Annabel C. Kleinwaechter & Eva M. Eisemann & Jabir Aliyu Muhammad & Jemima Helen & Tom Lakomy & Quirin Krabichler & Rachel Breton & Virginie Andry & Maria-Angeles Carrillo-de Sauvage & Valérie Demais & Aurélia Cès & Felix Franke & Franziska Schommer & Mélanie Kremer & Barbara Di Benedetto & Yannick Goumon & Christian P. Schaaf & Valery Grinevich & Nathalie Rouach & Pascal Darbon & Inga D. Neumann & Antoine Adamantidis & Marta Busnelli & Lucile Benhaim & Jeroen Krijgsveld & Frank W. Pfrieger & Alexandre Charlet
- 1-20 Alternative antigen retention by a gp96-fusion approach induces long-lasting and broad immunity in mice
by Fang Cheng & Baifeng Wang & Xinran Zhu & Zihao Wang & Haoyu Wang & Rui Li & Chan Xing & Ying Ju & Rongguo Wei & Xin Li & Songdong Meng
- 1-20 Anti-CSF-1R therapy with combined immuno-chemotherapy coordinate an adaptive immune response to eliminate macrophage enriched triple negative breast cancers
by Diego A. Pedroza & Xueying Yuan & Fengshuo Liu & Hilda L. Chan & Christina Zhang & William Bowie & Alex J. Smith & Sebastian J. Calderon & Nadia Lieu & Weiguo Wu & Paul Porter & Poonam Sarkar & Na Zhao & Constanze V. Oehler & Ondrej Peller & M. Waleed Gaber & Qian Zhu & Charles M. Perou & Xiang H-F. Zhang & Jeffrey M. Rosen
- 1-20 Benchmarking pre-trained genomic language models for RNA sequence-related predictive applications
by Ningyuan You & Chang Liu & Hai Lin & Sai Wu & Gang Chen & Ning Shen
- 1-20 Targeting of the m6A eraser ALKBH5 suppresses stemness and chemoresistance of colorectal cancer
by Heming Zhou & Huarong Chen & Weixin Liu & Cong Liang & Shiyan Wang & Kai Yuan & Alvin Ho Kwan Cheung & Yuet Wu & Wei Kang & Henley Cheung & Yanqiang Ding & Qinyao Wei & Hao Su & Tianhui Li & Weimei Luo & Sujun Chen & Chi Chun Wong & Jun Yu
- 1-20 Targeted antisense oligonucleotide treatment rescues developmental alterations in spinal muscular atrophy organoids
by Irene Faravelli & Paola Rinchetti & Monica Tambalo & Illia Simutin & Lisa Mapelli & Sara Mancinelli & Matteo Miotto & Mafalda Rizzuti & Andrea D’Angelo & Chiara Cordiglieri & Giulia Forotti & Clelia Peano & Paolo Kunderfranco & Luca Calandriello & Giacomo P. Comi & Elvezia Paraboschi & Eleonora Pali & Francesca Beatrice & Egidio D’Angelo & Serge Przedborski & Monica Nizzardo & Simona Lodato & Stefania Corti
- 1-20 CAV2-expressing nerves induce metabolic switch toward mitochondrial oxidative phosphorylation to promote cancer stemness
by Ze Zhang & Chunli Wang & Zhonghao Sun & Xiaotian Shi & Yanjie Shuai & Yafei Wang & Yun Wang & Hua Guo & Ruoyan Liu & Jingtao Luo
- 1-20 Extracellular matrix mediates circulating tumor cell clustering in triple-negative breast cancer metastasis
by Georg OM Bobkov & Khushali J. Patel & Bree M. Lege & Rong Zheng & Gad Shaulsky & Matthew J. Ellis & Chonghui Cheng
- 1-20 Nociceptive sensory neuron-derived NGF orchestrates a fibrotic mesenchymal stromal cell neurogenic niche to drive tendon pathological fibrosis
by Yanhao Li & Sa Pang & Xinshu Zhang & Mingkuan Lu & Junjie Zhao & Rongpu Wu & Jiacheng Hu & Jia Jiang & Huajiang Chen & Zemin Ling & Jun Qin & Bo Hu & Shen Liu
- 1-20 THRAP3 promotes ferroptosis resistance in acute myelocytic leukemia through SLU7-mediated alternative splicing of GIT2
by Dan Wang & Zhixiang Wu & Siyang Liu & Jing He & Haixia Zhang & Pan Chen & Minghua Yang
- 1-20 SETD1A regulates psychiatric gene networks involved in genomic stability and synaptic function in rare and sporadic schizophrenia
by Tomoyo Sawada & Arthur S. Feltrin & Yanhong Wang & Bruno Araujo & Alejandra E. McCord & Hunter H. Giles & Shizhong Han & Eugenia Radulescu & Qiang Chen & Bareera Qamar & André R. Barbosa & Ricardo S. Jacomini & Alan P. R. Lorenzetti & Violeta Dimitrova & Radka Kaneva & Vladimir Vladimirov & Joel E. Kleinman & Thomas M. Hyde & Daniel R. Weinberger & Apuã C. M. Paquola & Jennifer A. Erwin
- 1-20 Endothelial IRE1α promotes thrombospondin-1 mRNA decay and supports metabolic stress adaptation of pancreatic islets
by Xiaoge Zhang & Shijia Huang & Peng Chen & Ziyin Zhang & Jie Cai & Ting Yu & Zhixiong Xia & Shubo Yuan & Yong Chen & Mengjuan Gao & Zhuyin Wu & Jiongyi He & Yifei Liao & Qi Fu & Qiong Yang & Tailang Yin & Jie Liu & Ke Song & Sheng-Zhong Duan & Tao Yang & Liangyou Rui & Yi Arial Zeng & Zhuo-Xian Meng & Jianmiao Liu & Yong Liu
- 1-20 HIV-induced sialoglycans on infected CD4+ T cells promote immune evasion from myeloid cell-mediated killing
by Shalini Singh & S. M. Shamsul Islam & Rui Liu & Opeyemi S. Adeniji & Lacy M. Simons & Pratima Saini & Hiroaki Tateno & Ali Danesh & Paul W. Denton & Leila B. Giron & R. Brad Jones & Judd F. Hultquist & Han Xiao & Mohamed Abdel-Mohsen
- 1-20 A 7T fMRI dataset of synthetic images for out-of-distribution modeling of vision
by Alessandro T. Gifford & Radoslaw M. Cichy & Thomas Naselaris & Kendrick Kay
- 1-20 Modeling tissue-specific Drosophila metabolism identifies high sugar diet-induced metabolic dysregulation in muscle at reaction and pathway levels
by Sun Jin Moon & Yanhui Hu & Monika Dzieciatkowska & Ah-Ram Kim & John M. Asara & Angelo D’Alessandro & Norbert Perrimon
- 1-20 SPOROCYTELESS/NOZZLE cooperates with MADS-domain transcription factors to regulate an auxin-dependent network controlling Megaspore-Mother-Cell differentiation
by Alex Cavalleri & Chiara Astori & Silvia Manrique & Greta Bruzzaniti & Cezary Smaczniak & Chiara Mizzotti & Alessandro Ruiu & Mattia Spanò & Andrea Movilli & Veronica Gregis & Xiaocai Xu & Kerstin Kaufmann & Lucia Colombo
- 1-20 Egg-laying ChickenGTEx resource deciphers context-specific regulatory effects on fertility traits
by Di Zhu & Kai Shi & Chong Li & Yidan Yan & Houcheng Li & Zhonghao Bai & Lizhi Tan & Dailu Guan & Yiqiang Zhao & Yuzhe Wang & Baoliang Fan & Ziqin Jiang & Zhenqiang Xu & Chungang Feng & Lingzhao Fang & Xiaoxiang Hu
- 1-20 Butyrophilin 2A2 promotes T cell immunoregulation via CD45 phosphatase activation and protects against murine autoimmune glomerulonephritis and pregnancy loss
by Shafat Ali & Anders H. Berg & Michifumi Yamashita & Ambart E. Covarrubias & Jordan Mundell & Pranali N. Shah & Ruan Zhang & Vincent Dupont & Bong-Ha Shin & Shen Yang & Madhusudhanarao Katiki & Ramachandran Murali & Margareta D. Pisarska & Ravi Thadhani & Peter S. Heeger & Stanley C. Jordan & S. Ananth Karumanchi
- 1-20 Loss of Fsr quorum sensing promotes biofilm formation and worsens outcomes in enterococcal infective endocarditis
by Haris Antypas & Verena Schmidtchen & Willy Isao Staiger & LI Yanhong & Rachel Jing Wen Tan & Kenneth Kok Fei NG & Cheryl Jia Yi Neo & Shalome Meera Radhesh & Frederick Reinhart Tanoto & Ronni Anderson Gonçalves da Silva & Cristina Colomer-Winter & Sara Doina Schütz & Joachim Kloehn & Logeshwari Muthualagu Natarajan & Caroline Manzano & Jun Jie Wong & Kevin Pethe & Barbara Hasse & Silvio Daniel Brugger & Siu Ling Wong & Daria Van Tyne & Annelies S. Zinkernagel & Kimberly A. Kline
- 1-20 Ion channel inhibition by targeted recruitment of NEDD4-2 with divalent nanobodies
by Arden Darko-Boateng & Emmanuel Afriyie & Travis J. Morgenstern & Sri Karthika Shanmugam & Xinle Zou & Yianni D. Laloudakis & Papiya Choudhury & Meera Desai & Robert S. Kass & Francesca Vallese & Oliver B. Clarke & Henry M. Colecraft
- 1-20 Circulating causal protein networks linked to future risk of myocardial infarction
by Sean Bankier & Valborg Gudmundsdottir & Thorarinn Jonmundsson & Heida Bjarnadottir & Joseph Loureiro & Lingfei Wang & Elísabet A. Frick & Nancy Finkel & Anthony P. Orth & Thor Aspelund & Lenore J. Launer & Johan L. M. Björkegren & Lori L. Jennings & John R. Lamb & Vilmundur Gudnason & Tom Michoel & Valur Emilsson
- 1-20 IL-17a induces age-related olfactory dysfunction by impairing regeneration and promoting respiratory metaplasia in mice
by Shenglei Wang & Xudong Cha & Yingqi Xie & Zengyi Xu & Boyu Cai & Fengzhen Li & Tengfei Li & Zhe Wang & Tianyu Wang & Yiqun Yu & Huanhai Liu & Wenwen Ren
- 1-20 Intersectional biases in narratives produced by open-ended prompting of generative language models
by Evan Shieh & Faye-Marie Vassel & Cassidy R. Sugimoto & Thema Monroe-White
- 1-20 Mechanistic insights into recruitment and regulation of the RNA helicase UPF1 in replication-dependent histone mRNA decay
by Alexandrina Machado de Amorim & Guangpu Xue & Wenxia He & Theresa Dittmers & Sarah Lewandowski & Cecilia Perez-Borrajero & Juliane Bethmann & Nevena Mateva & Clemens Krage & Vidhyadhar Nandana & Bernhard Loll & Tarek Hilal & Janosch Hennig & Henning Urlaub & William F. Marzluff & Sutapa Chakrabarti
- 1-20 Airway immune profiles and therapeutic implications of IGF1 in eosinophilic granulomatosis with polyangiitis
by Cong Dong & Bingtai Lu & Changhao Zhong & Changxing Ou & Xiaojing Yang & Lingwei Wang & Xiaoyu Zuo & Lingna Xue & Chenyang Lu & Shang Wang & Junjie Wen & Jianjuan Ma & Zhenan Deng & Yiyi Liu & Liuheyi Ma & Ming Liu & Andrew M. Lew & Manali Mukherjee & Parameswaran Nair & Nanshan Zhong & Rongchang Chen & Zhanghua Chen & Yuxia Zhang & Qingling Zhang
- 1-20 Ovarian cancer metastasis to the human omentum disrupts organ homeostasis and induces fundamental tissue reprogramming
by Ulrike Lischetti & Ching-Yeu Liang & Matteo Carrara & Ricardo Coelho & Antoine Hanns & Flavio Lombardo & Arthur Dondi & Sandra Goetze & Michal Hensler & Christian Kurzeder & Céline Montavon & Jitka Fucikova & Franziska Singer & Niko Beerenwinkel & Christian Beisel & Viola Heinzelmann-Schwarz & Francis Jacob
- 1-20 Spatiotemporal coupling of caveolae mechanosensing and RhoA-GEFs regulates cell polarity and directional migration
by Vibha Singh & Victor Breton & Christine Viaris de Lesegno & Anne-Sophie Macé & Philippe Bun & Cédric M. Blouin & Amit Singh Vishen & Pierre Sens & Christophe Lamaze
- 1-20 Impaired glycolysis-derived serine metabolism as a key driver of podocyte injury with senescence
by Hongtu Hu & Zijing Zhu & Lanlan Li & Jijia Hu & Qian Yang & Zhuan Peng & Weiwei Li & Xiaofei Cui & Yanqin Fan & Wenjie Chen & Wei Liang & Zhaowei Chen & Guohua Ding
- 1-20 A protein complex in the extreme distal tip of vertebrate motile cilia controls their organization, length, and function
by Juyeon Hong & Chanjae Lee & Gopika Madhu & Ophelia Papoulas & Ece Atayeter & Gabriel Hoogerbrugge & Jiehong Pan & Maki Takagishi & Nadia I. Manzi & Daniel J. Dickinson & Amjad Horani & Steven L. Brody & Edward M. Marcotte & Vivek N. Prakash & Tae Joo Park & John B. Wallingford
- 1-20 Chimeras co-targeting antigens and FcγRIIb trigger degradation of extracellular soluble proteins and pathological aggregates
by Mingjuan Du & Na Li & Tianqi Li & Zhuoqian Zhao & Huanzhen Liu & Xin Li & Nanxin Gong & Baoxin Duan & Wenli Wang & Yi Jian & Wenxuan Ma & Xiaoqi Zhang & Yi Wang & Zhaoyuan Zhang & Yiyang Bai & Xiaoqian Wang & Chunlei Wang & Jinming Liu & Xiangchen Guan & Feilong Zhou & Wei Wang & Lili Li & Xingping Zhu & Ying Lei & Yinkai Duan & Guoge Han & Pinghui Wei & Shan Gao & Sheng Wang & Ancheng Chen & Yi Huang & Haitao Yang & Xue Xue & Hongkai Zhang
- 1-20 BATF2 is a glutamine-responsive tumour suppressor required for type-I interferon-dependent anti-tumour immunity
by Wang Gong & Hülya F. Taner & Yuesong Wu & Yumin He & Xingwu Zhou & Zaiye Li & Xin Hu & Charisse Ursin & Kala Chand Debnath & Kohei Okuyama & Qiang Hu & Christopher R. Donnelly & Felipe Nör & Chamila D. Perera & Emily Bellile & Arash Yunesi & Zhiqian Zhai & Mei Zhao & Wanqing Cheng & Zackary R. Fitzsimonds & Luke Broses & Jiaqian Li & Shadmehr Demehri & Deepak Nagrath & Gregory T. Wolf & Andrew G. Sikora & Yanbao Yu & Haitao Wen & Lei Wei & Steven B. Chinn & Jeffrey N. Myers & Shizuo Akira & Yuying Xie & James J. Moon & Yu Leo Lei
- 1-20 Deep learning-assisted discovery of a potent and cell-active inhibitor of RNA N6-methyladenosine recognition protein YTHDC2
by Zhenyu Yang & Weining Sun & Qiao Huang & Yueyue Li & Meng Yuan & Yu Yang & Heng Zhao & Zheyi Liu & Xiaoxi Zeng & Fangjun Wang & Yuanyuan Jiang & Yi Zhao & Runsheng Chen
- 1-20 Decoding necrosome assembly: harmonizing signal amplification and attenuation through optimal RIP3 stoichiometry
by Xiang Li & Yating Cao & Fei Xu & Yiting Zhang & Yue Kong & Chengjie Lan & Rongfeng Zhu & Cheng Lin & Chuan-Qi Zhong & Zhilong Liu & Hong Qi & Yichuan Huang & Yunshan Xiao & Gui-Quan Sun & Jianwei Shuai & Xin Chen
- 1-20 Segmented filamentous bacteria undergo a structural transition at their adhesive tip during unicellular to filament development
by Ana Raquel Cruz & Benedikt H. Wimmer & Teck Hui Teo & Gérard Pehau-Arnaudet & Jean-Marie Winter & Anastasia D. Gazi & Pierre Lafaye & Sébastien Brier & Agnès Legrand & Anna Dubrovsky-Gaupp & Marion Bérard & Gabriel Aymé & Anna Sartori-Rupp & Ohad Medalia & Pamela Schnupf
- 1-20 Endoglin as a BMP9 co-receptor in vascular endothelial cells: prodomain displacement and TGFBRII recruitment
by Jingxu Guo & Karolina Kostrzyńska & Ioannis Kamzolas & Xudong Yang & Midory Thorikay & Eckart De Bie & Rowena J. Jones & Adam Brownstein & Lu Long & Christopher J. Rhodes & Allan Lawrie & Martin R. Wilkins & Esmee Groeneveld & Zhen Tong & Marie-José Goumans & Evangelia Petsalaki & Jason Hong & Mark R. Toshner & Antonio Vidal-Puig & Helen M. Arthur & Wei Li
- 1-20 Targeting LRBA triggers CTLA4 degradation and antitumor immunity for cancer immunotherapy
by Xiaolu Ge & Liang Yu & Lei Zhang & Liqing Jia & Mingjing Meng & Jingquan He & Fan Bu & Yue Song & Gaorui Sun & Shiming Lv & Desheng Mei & Yutao Yang & Dakang Xu & Jingfa Zhang & Shengping Zhang & Chuangui Wang & Deshui Jia & Yongping Chen & Yue Gao & Baokun He
- 1-20 Temporal gene regulation enables controlled expression of gas vesicles and preserves bacterial viability
by Zongru Li & Chia-Yu Ho & Diana E. Barr & Sumin Jeong & Lihua Ma & George J. Lu
- 1-20 Advances, challenges and prospects of origami and kirigami optoelectronics
by Donggyun Lee & Su-Bon Kim & Junho Kim & Seunghyup Yoo
- 1-20 Renal insulin-like growth factor binding-protein 7 is a critical promoter of progressive diabetic kidney disease
by Ju-tao Yu & Xiao-wei Hu & Jia-nan Wang & Qin Yang & Xiang-yu Li & Run-run Shan & Tian Pu & Rui Hou & Xiao-yu Shen & Yu-qin Wang & Fei Zhang & Xiao-wen Yu & Jie Wang & Feng-he Li & Jia-gen Wen & Ying Fan & Juan Jin & Yi-yang Jiang & Xiao-ming Meng
- 1-20 Dysregulated hippocampal fatty acid metabolism following intermittent hypoxemia-induced neonatal brain injury is rescued by treatment with acetate
by Regina F. Fernandez & Wedad Fallatah & Yuanyuan Ji & Jace W. Jones & Cole C. Johnson & Caitlin M. Tressler & Kristine Glunde & Rida Ali & Ann B. Moser & Michael J. Wolfgang & Susanna Scafidi & Joseph Scafidi
- 1-20 Mechanosensitive dynamics of lysosomes along microtubules regulate leader cell emergence during collective cell migration
by Rituraj Marwaha & Diya Manoj & Simran Rawal & Purnati Khuntia & Sanak Banerjee & Praver Gupta & Basil Thurakkal & Manish Jaiswal & Tamal Das
- 1-20 Nucleophosmin 1 lactylation in graft kidney induces ferroptotic trigger waves that exacerbate delayed graft function
by Haitao Yu & Hubin Yin & Yuhua Mei & Xuesong Bai & Chunlin Zhang & Zhenwei Feng & Mao Li & Haonan Chen & Simin Liang & Xin Gou & Wenlong Zhong & Weiyang He & Jie Li & Tianxin Lin & Xinyuan Li
- 1-20 Little millet genome reveals evolutionary insights into tetraploid structure and genetic basis of micronutrient density
by Krishna Kishore Gali & Kevin C. Koh & Tara Chellapilla Satyavathi & Ganapathy Kuyyamudi Nanaiah & K. B. Palanna & Morgan W. Kirzinger & Sandeep Nanjundappa & Sampath Perumal & Deekshitha Bomireddy & H. B. Mahesh & Harshal Eknath Patil & Raju Chaudhary & Loveleen Kaur Dhillon & Venkat Bandi & V. B. Reddy Lachagari & Surya Teja Veeramachaneni & Renuka Malipatil & Peng Gao & Shankar Pahari & Andrew G. Sharpe & Thomas D. Warkentin & Raju Soolanayakanahally & M. K. Prasannakumar & Nepolean Thirunavukkarasu & Sateesh Kagale
- 1-20 Chemotherapy-induced adipo-lineage cell senescence drives bone loss
by Ganesh Kumar Raut & Taylor Malachowski & Anupama Melam & Renata Ramalho-Oliveira & Taylor Holt & Xianmin Luo & Zhangting Yao & Douglas V. Faget & Qihao Ren & David G. DeNardo & Sheila A. Stewart
- 1-20 Measuring and locating the changes in protein structure using MELO
by Lingyan Zheng & Yang Liao & Yintao Zhang & Mingxuan Liu & Mingkun Lu & Tingting Fu & Shuiyang Shi & Xiuna Sun & Chengbin Gu & Huaicheng Sun & Minjie Mou & Haibin Dai & Feng Zhu
- 1-20 Cohesin forms fountains at active enhancers in C. elegans
by Bolaji N. Lüthi & Jennifer I. Semple & Anja Haemmerli & Saurabh Thapliyal & Kalyan Ghadage & Klement Stojanovski & Dario D’Asaro & Moushumi Das & Nick Gilbert & Dominique A. Glauser & Benjamin Towbin & Daniel Jost & Peter Meister
- 1-21 Combined targeted and epigenetic-based therapy enhances antitumor immunity by stabilizing GATA6-dependent MHCI expression in pancreatic ductal adenocarcinoma
by JuanFei Peng & JiaJin Yang & Georgia Antonopoulou & Rui Fang & Bikash Adhikari & Markus Vogt & Elmar Wolf & Chong Sun & Shangce Du & Laura Godfrey & Aayush Gupta & Marija Trajkovic-Arsic & Nicole Teichmann & Barbara T. Grünwald & Niklas Krebs & Katja Steiger & Carolin Mogler & Kristina Althoff & Xin Wang & Giovanni Giglio & Sven-Thorsten Liffers & Konstantinos Savvatakis & Rickmer Braren & Rita T. Lawlor & Aldo Scarpa & Diana Behrens & Karl S. Lang & Phyllis F. Cheung & Jens T. Siveke
- 1-21 Glycerol 3-phosphate acyltransferase exacerbates α-synuclein-induced toxicity by increasing lipid peroxidation
by Mengda Ren & Grace G. Y. Lim & Willcyn Tang & Kah-Leong Lim
- 1-21 Binary mineral nanoparticles enable intravascular delivery of metal ions to tumors for metalloimmunotherapy
by Bao Loc Nguyen & Ngoc Duy Le & Thi Oanh Oanh Nguyen & Daehyeon Ahn & Basavaraj Rudragouda Patil & Beomsu Kim & Cao Dai Phung & Duc-Vinh Pham & Jung Min Lee & Jiwoo Hong & Jae-Hoon Chang & Sae Kwang Ku & Jeonghwan Kim & Jong Oh Kim
- 1-21 Chlorella-derived extracellular vesicle-based nanogels suppress cGAS-STING for treatment of radiation-induced lung injury
by Huiqun Hu & Feng Lu & Wenting Zhang & Zengwen Zhang & Jiarong Cui & Xiaoyue Lei & Jingyan Xia & Feng Xu
- 1-21 CXCR4 induces memory formation over exhaustion in CAR-T cells to achieve durable leukemia targeting
by Ari Itoh-Nakadai & Minggao Liang & Michiho Shindo & Chen Bibi & Mariko Tomizawa-Murasawa & Saera Fujiki & Akiko Kaneko & Emi Kanamaru & Mari Hashimoto & Hiroshi Kajita & Yoshinari Ando & Miki Kojima & Jonathan Moody & Makoto Iwasaki & Shinsuke Takagi & Ryo Nakagawa & Saumya Agrawal & Hanae Amitani-Iijima & Kaori Sato & Yuriko Sorimachi & Nahoko Suzuki & Takehiro Fukami & Kazuharu Hanada & Satoshi Morita & Kazushige Katsura & Takehisa Matsumoto & Maiko Kobayashi & Masahiko Kato & Yasuyuki Negishi & Mikako Shirouzu & Yuho Najima & Keiyo Takubo & Chung Chau Hon & Naoyuki Uchida & Shuichi Taniguchi & Yukihide Momozawa & Piero Carninci & Leonard D. Shultz & Yoriko Saito & Michiel de Hoon & Jay W. Shin & Fumihiko Ishikawa
- 1-21 Chamber-specific chromatin architecture guides functional interpretation of disease-associated Cis-regulatory elements in human cardiomyocytes
by S. Haydar & R. Bednarz & P. Laurette & I. Sobitov & N. Díaz i Pedrosa & P. Videm & T. Lueneburg & S. Kuß & H. Lahm & M. Dreßen & M. Krane & C. Schmidt & B. A. Grüning & N. Voigt & K. Streckfuss-Bömeke & R. Gilsbach
- 1-21 Biomimetic model of corticostriatal micro-assemblies discovers a neural code
by Anand Pathak & Scott L. Brincat & Haris Organtzidis & Helmut H. Strey & Sageanne Senneff & Evan G. Antzoulatos & Lilianne R. Mujica-Parodi & Earl K. Miller & Richard Granger
- 1-21 Tmem110 regulates the conformation of TRPML1 to maintain endolysosomal homeostasis and prevent mitochondrial DNA leakage and pathological self-DNA processing
by Zunyong Feng & Yuanbo Pan & Jing Zhou & Liuxi Chu & Qiang Li & Xuanbo Zhang & Ping Wu & Zhiliang Xu & Yanjiao Huang & Jianhua Zou & Xiaokun Li & Xiaoyuan Chen & Zhouguang Wang
- 1-21 Triple targeting of STING, TGF-β, and PD-L1 boosts CXCL16–CXCR6 signaling for potent antitumor response
by Ming Yi & Tianye Li & Yinhui Gu & Mengke Niu & Dixuan Xue & Shengtao Hu & Yuze Wu & Bin Zhao & Di Zhang & Yingkang Ma & Minjun Zhang & Jing Zhang & Yongxiang Yan & Pengfei Zhou & Xiaojun Zhang & Zhuxian Zhou & Qian Chu & Kongming Wu & Zhijun Dai
- 1-21 Loss-of-function variants in the CAPN1 activator CD99L2 cause X-linked spastic ataxia
by Benita Menden & Rana D. Incebacak Eltemur & German Demidov & Marc Sturm & Joohyun Park & Chrisovalantou Huridou & Florian Fath & Astrid Nümann & Alexander Baumann & Illja J. Diets & Claudia Dufke & Martin Regensburger & Maria Rönnefarth & Vera Wilke & Nienke van Os & Stefan Vielhaber & Tim W. Rattay & Zacharias Kohl & Susana Peralta & Priscila Pereira Sena & Melanie Kellner & Nadine Weissert & Andreas Traschütz & Lena Zeltner & Kai Boelmans & Natalie Deininger & Leon Schütz & Caspar Gross & Ana Beatriz Hinojosa Amaya & Katrin Raupach & Holger Hengel & Florian Harmuth & Jakob Admard & Ingrid Bader & Sarah Baumann & Friedemann Bender & Andrea Bevot & Almut Bischoff & Felix Boschann & Rebecca Buchert & Daniel Buchzik & Nicolas Casadei & Claudia B. Catarino & Isabell Cordts & Kirsten Cremer & Marion Doebler-Neumann & Nadja Ehmke & Miriam Elbracht & Ruth J. Falb & Thomas Feindt & Zofia Fleszar & Lea Gerstner & Dieter Gläser & Ute Grasshoff & Sarah Grosch & Kathrin Grundmann & Alexander Gutschalk & Manja Haaga & Stefanie Hayer & Ute Hehr & Yorck Hellenbroich & Wolfram Henn & Barbara Herr & Rebecca Herzog & Veronka Horber & Jonas Deppe & Nadja Kaiser & Christiane Kehrer & Martin Kehrer & Jan Kern & Christoph Keßler & Katharina Khuller & Hannah Klinkhammer & Urania Kotzaeridou & Peter Krawitz & Martina Kreiss & Hanna Küpper & Alice Kuster & Lucia Laugwitz & Anne Lesemann & Nadine Lichey & Tobias Linden & Boris Macek & Janine Magg & Elisabeth Mangold & Eva Manka & Iris Marquardt & Karl Mehnert & David Mengel & Susanne Morlot & Barbara Oehl-Jaschkowitz & Martje G. Pauly & Melanie Philipp & Florentine Radelfahr & Maren Rautenberg & Angelika Riess & Carsten Saft & Beate Schlotter-Weigel & Axel Schmidt & Eva M. C. Schwaibold & Veronika Spahlinger & Stephanie Spranger & Katharina Marie Steiner & Claudia Stendel & Andreas Thieme & Andreas Tzschach & Ana Velic & Sarah Wiethoff & Carlo Wilke & Stephan Züchner & Simone Zittel & Ralf A. Husain & Marcus Deschauer & Felix Distelmaier & Andreas Dufke & Holm Graessner & Bernhard Hemmer & Heike Jacobi & Thomas Klockgether & Thomas Klopstock & Xenia Kobeleva & Georg-Christoph Korenke & Alma Kuechler & Gregor Kuhlenbäumer & Ingo Kurth & Huu Phuc Nguyen & Gilbert Wunderlich & Kirsten E. Zeuner & Stephan Klebe & Michaela Auer-Grumbach & Michaela Butryn & Jürgen Winkler & Dagmar Timmann & Matthis Synofzik & Bart van de Warrenburg & Rebecca Schüle & Ludger Schöls & Stephan Ossowski & Olaf Riess & Jonasz J. Weber & Tobias B. Haack
- 1-21 Systems acclimation to osmotic stress in zygnematophyte cells
by Jaccoline M. S. Zegers & Lukas Pfeifer & Tatyana Darienko & Kerstin Schmitt & Craig A. Dorsch & Cäcilia F. Kunz & Gerhard H. Braus & Birgit Classen & Oliver Valerius & Jan de Vries
- 1-21 FGF7 promotes load-bearing tendon regeneration and suppresses fibrosis
by Ruifu Lin & Junchao Luo & Hong Zhang & Chunmei Fan & Yue Hu & Ruojin Yan & Zetao Wang & Yang Fei & Chenqi Tang & Tianxi Huang & Tianshun Fang & Weiliang Shen & Sunbin Ling & Hongwei Ouyang & Xiao Chen & Zi Yin
- 1-21 Interplay between T3SS effectors, ExoY activation, and cGMP signaling in Pseudomonas aeruginosa infection
by Vincent Deruelle & Gabrielle Dupuis & Dorothée Raoux-Barbot & Elysa Lim & Roberto Ponce-López & Magda Teixeira Nunes & Daniel Ladant & Louis Renault & Undine Mechold
- 1-21 DDX6 undergoes phase separation to modulate metabolic plasticity and chemoresistance
by Hongjie Bi & Wei Li & Lili Ren & Honghai Zhang & Lei Dong & Anthony Chan & Xueer Wang & Lu Yang & Xiaoxu Zhang & Meilin Xue & Hanjun Qin & Xiwei Wu & Johanna Ten Hoeve-Scott & Bin Zhang & Ling Li & Mark Wunderlich & James C. Mulloy & Steven T. Rosen & Jianjun Chen & Xiaobo Li & Chun-Wei Chen & Rui Su
- 1-21 Activation of hypothalamic-pontine-spinal pathway promotes locomotor initiation and functional recovery after spinal cord injury in mice
by Chengyue Ji & Yunfan Zhang & Zeyu Lin & Ziqi Zhao & Zhuolei Jiao & Zhiyuan Zheng & Xiaoxue Shi & Xiaofei Wang & Ziyu Li & Shuisheng Yu & Yun Qu & Yaxuan Wei & Tan Rui & Bowen Zheng & Taorong Xie & Hanyu Shi & Qifang Wang & Xiao Yu & Xiaohong Xu & Juxiang Chen & Jin Fan & Weihua Cai & Yi Li
- 1-21 A SET domain-containing protein and HCF-1 maintain transgenerational epigenetic memory
by Chenming Zeng & Giulia Furlan & Miguel Vasconcelos Almeida & Juan C. Rueda-Silva & Jonathan Price & Helena Santos-Rosa & Jingxiu Xu & Yan Kuang & Enric Cata Socias & Jonas Mars & Pedro Rebelo-Guiomar & Meng Huang & Shouhong Guang & Falk Butter & Eric A. Miska
- 1-21 TMEM120A maintains adipose tissue lipid homeostasis through ER CoA channeling
by Yoon Keun Cho & Junhyuck Lee & Yujin L. Jeong & Minki Shim & Xuan Linh Mai & Chang Seomoon & Cheol Woon Jung & Yoon Ha Choi & Sik Namgoong & Young-Suk Jung & Sung Won Kwon & Juyong Lee & Je Kyung Seong & Sunghyouk Park & Emilio P. Mottillo & James G. Granneman & Dong-Kyu Lee & Jong Kyoung Kim & Yun-Hee Lee
- 1-21 Time-dependent deployment of medial prefrontal cortical representations in male mice
by Junior Samuel Lopez-Yepez & Anna Barta & Juliane Martin & Maria Moltesen & Tsz-Fung Woo & Oliver Hulme & Ebru Demir & Duda Kvitsiani
- 1-21 Multi-modal AI for opportunistic screening, staging and progression risk stratification of steatotic liver disease
by Yuan Gao & Chunli Li & Wanxing Chang & Bai Du & Xianghua Ye & Yee Hui Yeo & Yingda Xia & Heng Guo & Xiaoming Zhang & Wei Liu & Ruobing Bai & Beibei Li & Yang Hong & Jiawen Yao & Le Lu & Kai Cao & Ke Yan & Jun Chen & Jie Li & Yang Hou & Ling Zhang & Yu Shi
- 1-21 Adaptation to cystine limitation stress confers a targetable lipid metabolism vulnerability in pancreatic ductal adenocarcinoma
by Yunzhan Li & Zekun Li & Qin Li & Dongxiao Sun & Bo Ni & Mingjun Tan & Ashley E. Shay & Min Wang & Chenyang Meng & Guangcong Shen & Boyang Fu & Yueying Shan & Shiqi Zhang & Rifah Rownak Tanshee & Tianxing Zhou & Yongjie Xie & Kun-Ming Chen & Bin Qiao & Yunkun Dang & Scot R. Kimball & Guanshi Zhang & Girish H. Rajacharya & Pankaj K. Singh & Xiuchao Wang & Jihui Hao & Shengyu Yang
- 1-21 Prodrug nanoplatform for triggering ferroptosis to eliminate senescent cells in age-associated pathologies
by Chengkang Jin & Xiaoling Xu & Ning Yao & Hairui Zhang & Changjiang Chen & Lingyao Zeng & Zhiyun Liu & Lanjie Lei & Shumao Cui & Chengping Wen & Liyun Shi
- 1-21 Rapid endothelialization of printed vascular grafts by perivascular niche-circulating endothelial progenitors crosstalk
by Zhe-qian Zhang & Ping-Ping Yuan & Cong Yao & Yu-xin Lu & Yi-dong Hu & Zhen-nan Qiu & Wen-yu Zhan & Xin-chi Zhang & Yu-jiao Wang & Xiao-peng Wu & Ya-jing Zhao & Peng-yu Wang & Ning Leng & Cun Zhang & Jian-kang He & Wei Wu
- 1-21 Mechanical rejuvenation of senescent stem cells and aged bone via chromatin remodeling
by Xiaojing Liu & Yuanxin Ye & Zhonghan Li & Li Liao & Qiang Wei
- 1-21 Leveraging genomic and transcriptomic data of diverse ancestry to uncover mechanisms of psychiatric risk in the adult and developing brain
by Aarti Jajoo & Vijetha Balakundi & Chris Chatzinakos & Athina Aruldass & Cindy Wen & Ilse G. C. Kolmans & Artemis Iatrou & Joel E. Kleinman & Kerry J. Ressler & Tim Bigdeli & Michael J. Gandal & Nikolaos P. Daskalakis
- 1-21 Peptide-functionalized membrane camouflage for endogenous H2S-induced photothermal immunotherapy of orthotopic colorectal cancer
by Kai Cheng & Fang Zhang & Jia-Hua Zou & Xiao-Ling Lei & Xiao-Ting Xie & Yan-Bin Guo & Guo-Ping Wang & Bo Liu & Yuan-Di Zhao & Jiang Xia & Jin-Xuan Fan
- 1-21 Mapping rare protein-coding variants on multi-organ imaging traits
by Yijun Fan & Jie Chen & Zirui Fan & Julio Chirinos & Jason L. Stein & Patrick F. Sullivan & Rujin Wang & Ajay Nadig & David Y. Zhang & Shuai Huang & Zhiwen Jiang & Peter Yi Guan & Xinjie Qian & Ting Li & Haoyue Li & Zehui Sun & Marylyn D. Ritchie & Joan M. O’Brien & Walter Witschey & Daniel J. Rader & Tengfei Li & Hongtu Zhu & Bingxin Zhao
- 1-21 Fidelity in co-diversified symbiosis
by Inès Pons & Marleny García-Lozano & Christiane Emmerich & Aftab Mahmood Ayas & Christine Henzler & Hagay Enav & Ruth E. Ley & Hassan Salem
- 1-21 Autophagic extracellular vesicles (AEVs) are distinct from exosomes and play crucial roles in viral infections
by Kedan Mao & Fangfang Huo & Hongqi Wei & Furong Wang & Sidong Xiong & Yuxuan Fu
- 1-21 Eye movements during free viewing to maximize scene understanding
by Shravan Murlidaran & Miguel P. Eckstein
- 1-21 Natural degradation of RNA polymerase II is essential for oocyte chromatin reorganization and maternal-to-zygotic transition
by Jing Wang & Wang Li & Jing Guo & Xiaoming Xu & Ge Lin & Bin Li & Chun So
- 1-21 Cross-ancestry comparison of aptamer and antibody protein measures
by Jayna C. Nicholas & Daniel H. Katz & Usman A. Tahir & Catherine L. Debban & Francois Aguet & Thomas Blackwell & Russell P. Bowler & K. Alaine Broadaway & Jingsha Chen & Clary B. Clish & Josef Coresh & Elaine Cornell & Daniel E. Cruz & Rajat Deo & Margaret F. Doyle & Peter Durda & Lynette Ekunwe & James S. Floyd & Dipender Gill & Xiuqing Guo & Ron C. Hoogeveen & Craig Johnson & Leslie A. Lange & Yun Li & Alisa Manning & James B. Meigs & Michael Y. Mi & Josyf C. Mychaleckyj & Nels C. Olson & Katherine A. Pratte & Brucy M. Psaty & Alexander P. Reiner & Peifeng Ruan & Magdalena Sevilla-Gonzalez & Amil M. Shah & Quan Sun & Russell P. Tracy & Jia Wen & Alexis C. Wood & James G. Wilson & Kristin L. Young & Bing Yu & Mary R. Rooney & Ani Manichaikul & Ruth Dubin & Karen L. Mohlke & Stephen S. Rich & Jerome I. Rotter & Peter Ganz & Robert E. Gerszten & Kent D. Taylor & Laura M. Raffield
- 1-21 Neural and computational mechanisms underlying one-shot perceptual learning in humans
by Ayaka Hachisuka & Jonathan D. Shor & Xujin Chris Liu & Daniel Friedman & Patricia Dugan & Ignacio Saez & Fedor E. Panov & Yao Wang & Werner Doyle & Orrin Devinsky & Eric K. Oermann & Biyu J. He
- 1-21 Design of precision therapeutics for a CKD risk allele by targeting Shroom3-Rock interaction
by Anand Reghuvaran & Ashwani Kumar & Qisheng Lin & Nallakandi Rajeevan & Khadija Banu & Zeguo Sun & Hongmei Shi & Gabriel Barsotti & EM Tanvir & John Pell & Sudhir Perincheri & Chengguo Wei & Bhavya Bharathan & Marina Planoutene & Anne Eichmann & Valeria Mas & Weijia Zhang & Lloyd G. Cantley & Leyuan Xu & Bhaskar Das & John Cijiang He & Madhav C. Menon
- 1-21 Precipitation disaster hotspots depend on historical climate variability
by Iris de Vries & Maybritt Schillinger & Erich Fischer & Sebastian Sippel & Reto Knutti
- 1-21 A CD8αβ co-receptor modified to contain an intracellular CD28 signaling tail enhances TCR-engineered T cell function independent of solid-tumor-associated co-stimulatory ligands
by Shihong Zhang & Tzu-Hao Tang & Sinéad Kinsella & Francesco Mazziotta & Michael T. Schweizer & Megan S. McAfee & Ariunaa Munkhbat & Yapeng Su & Valentin Voillet & Lauren E. Martin & Colton W. Smith & Yuta Asano & Menna Hailemariam & Jakob Bakhtiari & Bo Lee & Cecilia Yeung & Hung Chen & Alessandro M. Rizzi & Daniel G. Chen & Kelsey Furiya & Nick Horst & Tianzi Zhang & Phung Le & Kelly McKenna & Shannon K. Oda & Anthony Rongvaux & Phillip D. Greenberg & Thomas M. Schmitt & Aude G. Chapuis
- 1-22 A physics-informed graph neural network conserving linear and angular momentum for dynamical systems
by Vinay Sharma & Olga Fink
- 1-22 Whole body regeneration deploys a rewired embryonic gene regulatory network logic
by Rita Andreoni-Pham & Hereroa Johnston & Jacob F. Warner & Karine Nedoncelle & João E. Carvalho & Kai Hofmänner & Agata Maugeri & Olivier Croce & Aldine R. Amiel & Eric Röttinger
- 1-22 Integrated multi-omic atlas reveals the hierarchy of spatiotemporal regulatory networks of mouse gastrulation
by Xianfa Yang & Bingbing Xie & Penglei Shen & Yingying Chen & Chunjie Li & Fengxiang Tan & Yumeng Yang & Yun Yang & Rui Song & Panpan Mi & Zhiwen Liu & Mingzhu Wen & Patrick P. L. Tam & Shengbao Suo & Naihe Jing
- 1-22 Intratumoral delivery of FLT3L with CXCR3/CCR5 ligands promotes XCR1+ cDC1 infiltration and activates anti-tumor immunity
by Louise Gorline & Fillipe Luiz Rosa do Carmo & Pierre Bourdely & Jérémie Bornères & Nathan Vaudiau & Aurélie Semervil & Mathias Vetillard & Aboubacar Sidiki K Coulibaly & Natacha Jugniot & Agathe Ok & Mathilde Bausart & Oriane Fiquet & Marine Andrade & Dicken Fardol & Ikrame Haddar & Zeina Abou Nader & Judith Weber & Hannah Theobald & Matthieu Collin & Joseph Calmette & Giorgio Anselmi & Flavia Fico & Florent Ginhoux & Laleh Majlessi & Emmanuel L. Gautier & Loredana Saveanu & Julie Helft & Marc Dalod & Mathilde Dusseaux & James P. Di Santo & Stéphanie Hugues & Pierre Guermonprez
- 1-22 Lack of MDA5 delays hematopoietic aging by modulating inflammaging and proteostasis in mice
by Veronica Bergo & Pavlos Bousounis & Giang To Vu & Mélodie Douté & Aikaterini Polyzou & Maria-Eleni Lalioti & Bogdan B. Grigorash & Lyudmila Tsurkan & Nicholas Morchel & Ward Deboutte & Frédéric Brau & Thomas Manke & Sagar & Hind Medyouf & Dmitry V. Bulavin & Nina Cabezas-Wallscheid & Marta Derecka & Eirini Trompouki
- 1-22 Slower-growing species promote interspecific cooperation and coexistence under acid stress through cross-feeding
by Hui Liao & Liming Wu & Yi Luo & Hussain Asif & Xinlei Huang & Xiaole Xia
- 1-22 MYC drives left-handed Z-DNA formation to shape gene expression
by Xinyi Wan & Haonan Fan & Zhuoning Li & Yixuan Du & Yu Liu & Weiwu Zeng & Zhongxing Sun & Juejia Shao & Junqi Jia & Yanjun Zhang & Dong Fang
- 1-22 KY216-tubulin complex captures VASH2 to inhibit NSCLC metastasis
by Xiao-Yu He & Cheng-Yan Liu & Xin-Yu Ding & Qing Lin & Jia-Fu Leng & Cheng-Mei Xiao & Xin Zang & Meng-Yue Wang & Yong Yin & Ling-Yi Kong & Yuan-Zheng Xia
- 1-22 A pooled Cell Painting CRISPR screening platform enables de novo inference of gene function by self-supervised deep learning
by Srinivasan Sivanandan & Bobby Leitmann & Eric Lubeck & Mohammad Muneeb Sultan & Panagiotis Stanitsas & Navpreet Ranu & Alexis Ewer & Jordan E. Mancuso & Zachary F. Phillips & Albert Kim & John W. Bisognano & John Cesarek & Fiorella Ruggiu & David Feldman & Daphne Koller & Eilon Sharon & Ajamete Kaykas & Max R. Salick & Ci Chu
- 1-22 Capsaicin diet drives gut inflammation and exosomal miR-17-3p elevation in idiopathic short stature
by Yameng Wang & Zhiwen Wu & Jinghong Yuan & Junchao Zhu & Marco Ventin & Shahrzad Arya & Peng Yu & Giulia Cattaneo & Guowen Huang & Wenrui Zhao & Shengqin Li & Junqiu Zhang & Qi Chen & Xinhui Wang & Lianyong Li & Xijuan Liu & Xigao Cheng & Jingyu Jia
- 1-22 Inactive ryanodine receptors sustain lysosomal availability for autophagy by promoting ER-lysosomal contact site formation
by Tim Vervliet & Jens Loncke & Marko Sever & Karan Ahuja & Chris Van den Haute & Tomas Luyten & Grace E. Stutzmann & Catherine Verfaillie & Tihomir Tomašič & Geert Bultynck
- 1-22 De novo design of epitope-specific antibodies via a structure-driven computational workflow
by Fandi Wu & Yu Zhao & JiaXiang Wu & Biaobin Jiang & Bing He & Longkai Huang & Chenchen Qin & Yang Xiao & Fan Yang & Rubo Wang & Ningqiao Huang & Huaxian Jia & Yuyi Liu & Houtim Lai & Tingyang Xu & Fang Wang & Zihan Wu & Yidong Song & Shaoning Li & Wei Liu & Yu Rong & Peilin Zhao & Jianhua Yao
- 1-22 Volatile and non-volatile pathogen cues shape host extracellular vesicles production in pre-infection response
by Klaudia Kołodziejska & Agata Szczepańska & Satya Vadlamani & Ramakrishnan Ponath Sukumaran & Mariusz Radkiewicz & Henrik Bringmann & Nathalie Pujol & Wojciech Pokrzywa & Michał Turek
- 1-22 The inflammatory path toward type 1 diabetes begins during pregnancy
by Angelica P. Ahrens & Raquel Dias & Tuulia Hyötyläinen & Matej Orešič & Eric W. Triplett & Johnny Ludvigsson
- 1-22 Computational and neural mechanisms underlying the influence of action affordances on value learning
by Sanghyun Yi & John P. O’Doherty
- 1-22 A small molecule VDAC ligand inhibits ERAD and induces selective cancer cell death via disruption of calcium homeostasis
by Wenjing Yan & Daniel C. Talley & Antara Syam & Carina Danchik & Yongwang Zhong & Xianzheng Zhang & Xiaoying Liu & Bolormaa Baljinnyam & Stephen C. Kales & Matthew G. Cyr & Yuhong Fang & Alexey V. Zakharov & Xin Hu & Taylor Niehoff & Tuan Xu & Yanyan Qu & Allison Yang & Valentine V. Courouble & Qin Yao & Anton Simeonov & Ruili Huang & Tatiana K. Rostovtseva & Sergey M. Bezrukov & Christopher A. LeClair & Josephine M. Egan & Hua Wang & Dingyin Tao & Ganesha Rai & Mark J. Henderson & Shengyun Fang
- 1-22 Dynamic allele usage of X-linked genes ameliorates neurodevelopmental disease phenotypes in brain organoids
by M. Bertin & H. Todorov & S. Frank & S. Käseberg & R. Menon & E. Gabassi & C. Foerster & N. Bobon & F. Furlanetto & A. Soliman & H. M. B. Ibrahim & V. Engelhardt & L. Birschmann & H. Brennenstuhl & B. Lohrer & A. Mas-Sanchez & E. Cesare & J. Winter & J. Krummeich & J. Winkler & B. Winner & E. Weis & S. Diederich & K. Luck & P. Lunt & S. Gerber & P. Baumann & N. Elvassore & B. Berninger & MF Basilicata & S. Schweiger & S. Falk & M. Karow
- 1-22 Compression-induced NF-κB activation sustains tumor cell survival in confinement by detoxifying aldehydes and promotes metastasis
by Bing Liu & Min Liu & Yajuan Zhang & Yifei Zhu & Dingpei Zhou & Hong Gao & Fan Yang & Dong Gao & Yun Zhao & BangBao Tao & Feng Yao & Weiwei Yang
- 1-22 A human electrophysiological signature of Fragile X pathophysiology is shared in V1 of Fmr1-/y mice
by Sara S. Kornfeld-Sylla & Cigdem Gelegen & Jordan E. Norris & Francesca A. Chaloner & Maia Lee & Michael Khela & Maxwell J. Heinrich & Peter S. B. Finnie & Lauren E. Ethridge & Craig A. Erickson & Lauren M. Schmitt & Sam F. Cooke & Carol L. Wilkinson & Mark F. Bear
- 1-22 Identification of a lipid oxygen radical defense pathway and its epigenetic control
by Francisco S. Mesquita & Laurence Abrami & Romain Forey & Béatrice Kunz & Charlène Raclot & Lucie Bracq & Filipe Martins & Danica Milovanovic & Evarist Planet & Olga Rosspopoff & Didier Trono & F. Gisou van der Goot
- 1-22 Robust minimally-invasive microfabricated stainless steel neural interfaces for high resolution recording
by Zabir Ahmed & Ibrahim Kimukin & Vishal Jain & Kate Gurnsey & Tobias Teichert & Maysamreza Chamanzar
- 1-22 Inherent instability of simple DNA repeats shapes an evolutionarily stable distribution of repeat lengths
by Ryan J. McGinty & Daniel J. Balick & Sergei M. Mirkin & Shamil R. Sunyaev
- 1-22 Hypoxia-driven remodeling of SELENOP+ macrophages shapes T cell dynamics and promotes ovarian cancer metastasis
by Qing Liu & Chenzhao Feng & Tianhao Wu & Siyang Zhang & Xinyi Wang & Qian Zhao & Xueying Song & Shuangyan Liu & Linru Quan & Yuli Zhang & Shimin Zhang & Bin Yang & Jixin Li & Gang Chen & Xuanzhang Huang & Chaoyang Sun & Xin Zhou
- 1-22 ARMH4 accelerates aging by maintaining a positive-feedback growth signaling circuit
by Yu Fang & Baosen Wang & Qiuxiao Guo & Jian Lv & Jiajie Li & Junmei Wang & Ningning Guo & Yu Bai & Anqi Xu & Xiao Ma & Hui Tan & Hong Li & Zhihua Wang
- 1-22 Uncovering the molecular logic of cortical wiring between neuronal subtypes across development through ligand–receptor inference
by Rémi Mathieu & Tangra Draia-Nicolau & Léa Corbières & Annousha Govindan & Vianney Bensa & Emilie Pallesi-Pocachard & Lucas Silvagnoli & Alfonso Represa & Carlos Cardoso & Ludovic Telley & Antoine de Chevigny
- 1-22 Interaction and functional specialization across a distributed neural circuit for flexible task control in macaques
by K. Marche & N. Trudel & U. Schüffelgen & S. Smart & C. M. Harbison & J. Scholl & J. Sallet & F-X Neubert & J. Algermissen & N. Khalighinejad & JX O’Reilly & MC Klein-Flügge & MFS Rushworth
- 1-22 Targeting TNK2/ACK1 reverses the immunosuppressive tumor microenvironment and synergizes with immunochemotherapy in pancreatic cancer
by Chao Wu & Weishuai Liu & Xiangting Hu & Yongjie Xie & Shengnan Li & Xinyue Liu & Zhaojun Sun & Xiaoling Li & Xin Yu & Yudong Yuan & Yiping Zou & Ran An & Yanan Chen & Hailong Wang & Yukuan Feng & Song Gao & Hongwei Wang & Yifei Wang & Nan Wang & Chao Yang & Jun Yu & Peiqing Sun & Chongbiao Huang & Antao Chang & Jihui Hao
- 1-22 Residual tumor cells after insufficient radiofrequency ablation promote lung metastasis by educating CD177hiPAD4hi neutrophils
by Na Huang & Yisheng Fang & Siting Zheng & Jianhua Wu & Genjie Huang & Xinyue Deng & Yijin Guan & Bishan Liang & Dongqiang Zeng & Beibei Xu & Yuanwen Huang & Xiaoxiang Rong & Chunlin Wang & Jianping Bin & Yulin Liao & Zuqiang Wu & Min Shi & Wangjun Liao
- 1-22 A quantitative, multimodal wearable bioelectronic device for comprehensive stress assessment and sub-classification
by Xiaochang Pei & Anita Ghandehari & Shingirirai Chakoma & Jerome Rajendran & Jorge Alfonso Tavares-Negrete & Rahim Esfandyarpour
- 1-22 Intranasal blood-brain barrier bypass enables sequential mitochondria-targeted bioengineered nanolamellar system for ischemic stroke therapy
by Yue Yin & Zixuan Li & Weijie Shu & Hening Liu & Zihan Wang & Cong Fu & Yuanbo Zhu & Xuejing Li & Yi Zhang & Bei Lv & Zixuan Wang & Qiaoqiao Zhao & Dan Liu & Lu Tang & Wei Wang
- 1-22 Metabolic syndrome promotes endometrial cancer by Oleic acid-mediated polyamine accumulation
by Lirong Zhai & Yuan Cheng & Meixuan Wu & Tianzhuo Wang & Meichen Yin & Xiao Yang & Bowen Sun & Chengcheng Li & Miao He & Yi Sun & Yiqian Zhao & Yuqi Xing & Bo Liu & Ling Zhou & Yuanyuan Liu & Miao Yu & Yijiao He & Hongquan Zhang & Jun Zhan & Jianliu Wang
- 1-22 Chronic macrophage activation derails muscle repair by disrupting mannose-receptor-linked plasticity revealed by endogenous irg1/acod1 tracking
by Caroline G. Spencer & Matthew Hamilton & Ethan Bedsole & Yingshan N. Wei & Alison M. Rojas & Andrew Burciu & John Zhu & Keith Z. Sabin & Celia E. Shiau
- 1-22 Engineered VPg saRNA achieves cap-independent, low-immunogenic and precise encoding of therapeutic proteins in vivo
by Zunyong Feng & Liuxi Chu & Qiang Li & Jing Zhou & Ping Wu & Xuanbo Zhang & Yuanbo Pan & Jianhua Zou & Qun Chen & Zhiliang Xu & Liang Yan & Yanjiao Huang & Xiaokun Li & Zhouguang Wang & Xiaoyuan Chen
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