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Content
December 2026, Volume 17, Issue 1
- 1-17 mRNA vaccine developed for sequential selective organ-to-cell targeting of glioma
by Lin Shi & Yueying Li & Shiyun Huang & Jin Peng & Chuyao Liu & Zuoyu Hu & Wenbin Deng & Guanjun Deng
- 1-17 Molecular and epistatic interactions between pioneer transcription factors shape nucleosome dynamics and cell differentiation
by Rémi-Xavier Coux & Agnès Dubois & Almira Chervova & Inma Gonzalez & Sandrine Vandormael-Pournin & Michel Cohen-Tannoudji & Pablo Navarro
- 1-17 Multi-omic relay velocity modeling uncovers dynamic chromatin-transcription regulation across cell states
by Ari Hong & Sangseon Lee & Kwangsoo Kim
- 1-17 PTEN regulates vagal-insulin signaling to optimize autonomic output determining peripheral inflammatory and metabolic homeostasis
by Yu Zhe Li & Joe Eun Son & Nathaniel Vo & Catherine Bellisimo & Ju Hee Lee & Joshua Rapps & Evan Pollock-Tahiri & Martha Ghebreselassie & Chuck T. Chen & Richard P. Bazinet & Filio Billia & Akira Suzuki & Chi-Chung Hui & Tak W. Mak & Hoon-Ki Sung & Paul Yoo & Minna Woo
- 1-17 Pre- and postsynaptic upregulation of FasII synergistically underlies neuropathological and behavioral phenotypes in a Drosophila model of myotonic dystrophy
by Alex Chun Koon & Ka Yee Winnie Yeung & Yitao Wu & Lok I Leong & John Tsun Po Cheung & Zhefan Stephen Chen & Shaohong Isaac Peng & Noah S. Armstrong & C. Andrew Frank & Paul Magneron & Mário Gomes-Pereira & Joyce Man See Fung & Ariadna Bargiela & Nerea Moreno & Javier Poyatos-Garcia & Juan Vilchez & Aline Huguet-Lachon & Cassandra Kussius Brewer & Max Zinter & Erin S. Beck & Rubén Artero & Genevieve Gourdon & Vivian Budnik & Travis Thomson & Brian D. McCabe & Ho Yin Edwin Chan
- 1-17 Competing cognitive pressures on human exploration in the absence of trade-off with exploitation
by Clémence Alméras & Valerian Chambon & Valentin Wyart
- 1-17 Tissue-resident microbiota impacts colorectal cancer progression and prognosis
by Zhun Shi & Huahui Ren & Cong Lin & Fuqiang Li & Meizhen Wu & Fangming Yang & Tian Luo & Luís Nunes & Anders Isaksson & Klara Hammarström & Ting Zhu & Shida Zhu & Yiyi Zhong & Ingrid Ljuslinder & Mathias Uhlén & Richard Palmqvist & Bengt Glimelius & Kui Wu & Tobias Sjöblom & Huanzi Zhong
- 1-17 MiRNAs shape mouse age-independent tissue adaptation to spaceflight via ECM and developmental pathways
by Friederike Grandke & Shusruto Rishik & Viktoria Wagner & Annika Engel & Nicole Ludwig & Kruti Calcuttawala & Fabian Kern & Verena Keller & Marcin Krawczyk & Louis Stodieck & Virginia Ferguson & Amanda Roberts & Eckart Meese & Nicholas Schaum & Steven Quake & Tony Wyss-Coray & Andreas Keller
- 1-17 A chromosome region linked to neurodevelopmental disorders influences locomotor behavior through sex-specific neural circuits
by Jaekyoon Kim & Yann Vanrobaeys & Remya Rajan & M. Felicia Davatolhagh & Benjamin Kelvington & Snehajyoti Chatterjee & Sarah L. Ferri & Christopher Angelakos & Alea A. Mills & Marc V. Fuccillo & Kim T. Blackwell & Thomas Nickl-Jockschat & Ted Abel
- 1-17 Stress-trained microalgae robots with probiotics backpack and intestinal brake for inflammatory bowel disease management
by Ruifeng Luo & Jinwei Liu & Linxin Dai & Tianshun Duan & Qingwen Zhang & Cheng Gao & Ruibing Wang
- 1-17 Site-saturation functional screens identify PALB2 missense variants associated with increased breast cancer risk
by Rick A.C.M. Boonen & Sabine C. Knaup & Roberta Menafra & Merel E. Braspenning & Magdalena B. Rother & Petra Kleiblova & Marketa Janatova & Dina Ruano & Chunling Hu & Huaizhi Huang & Vijai Joseph & Michael Conry & Stephan Heijl & Bas Vroling & Jelle J. Goeman & Matthew Varga & Marcy E. Richardson & Susan L. Kloet & Fergus J. Couch & Maaike P. G. Vreeswijk & Haico van Attikum
- 1-17 ssG4-seq for global profiling of strand-specific G-quadruplex structures in mammalian genomes
by Sheng Li & Ruoyan Wang & Jinyue Zhang & Changchang Cao & Jiangshan Bai & Zhaokui Cai & Rong Ye & Juan Chen & Wanglong Liu & Chen Lu & Ruitian Li & Yuanchao Xue
- 1-17 Activity in human dorsal raphe nucleus signals changes in behavioural policy
by Luke Priestley & Ali Mahmoodi & William D. Reith & Nima Khalighinejad & Matthew F. S. Rushworth
- 1-17 An astrocytic ensemble at vHip-NAc synapses modulates cognitive impairments induced by chronic tetrahydrocannabinol exposure
by Cristina Martín-Monteagudo & Javier Sánchez Romero & Julia M. Adams & Nagore Puente & Pedro Grandes & Giovanni Marsicano & Ana Covelo & Baljit S. Khakh & Marta Navarrete
- 1-17 A lung CT vision foundation model facilitating disease diagnosis and medical imaging
by Zebin Gao & Guoxun Zhang & Hengrui Liang & Jiaxin Liu & Liangdi Ma & Tianyun Wang & Yanchen Guo & YuJia Chen & Zeping Yan & Xiangru Chen & Jianxing He & Feng Xu & Tien Yin Wong & Yuchen Guo & Qionghai Dai
- 1-17 Connectivity of the adult human brain with sequential neurogenesis of circuits and transcriptomics signatures
by Ibai Diez & Fernando García-Moreno & Nayara Carral-Sainz & Sebastiano Stramaglia & Alicia Nieto-Reyes & Mauro D’Amato & Jesús M Cortes & Paolo Bonifazi
- 1-17 Development of a replication-defective mpox virus platform for fundamental and therapeutic research
by Jiannan Chen & Liyuan Hu & Riccardo Vernuccio & Ning Shi & Jiaxin Tian & Yuyi Zhang & Sicheng Tian & Xinyu Cao & Zhuo Ha & Jiahan Lu & Leandro Battini & Bertrand Raynal & Ahmed Haouz & Jing Xue & Qiliang Cai & Yiqi Zhao & Yongxu Lu & Geoffrey L. Smith & Youhua Xie & Huijun Lu & Pablo Guardado-Calvo & Ping Zhang & Rong Zhang
- 1-17 Synthesizing selection mosaic theory and host-pathogen theory to explain large-scale pathogen coexistence
by Katherine P. Dixon & William T. Koval & Carlos M. Polivka & Grace Bird & Vanja Dukic & Greg Dwyer
- 1-17 Viral entry shapes HCMV latency establishment
by Yaarit Kitsberg & Aharon Nachshon & Tamar Arazi & Karin Broennimann & Tal Fisher & Alexander Wainstein & Yaara Finkel & Noam Stern-Ginossar & Michal Schwartz
- 1-17 Aiolos restricts the generation of antigen-inexperienced, virtual memory CD8+ T cells in mice
by Srijana Pokhrel & Gayathri Dileepan & Melissa R. Leonard & Robert T. Warren & Mariam Salem & Allison J. Yacapraro & Qiaoke Gong & Devin M. Jones & Jasmine A. Tuazon & Kaitlin A. Read & Jacob S. Yount & Gang Xin & Adriana Forero & Hazem E. Ghoneim & Patrick L. Collins & Emily A. Hemann & Kenneth J. Oestreich
- 1-17 Uncertainty-aware machine learning to predict non-cancer human toxicity for the global chemicals market
by Kerstin von Borries & Katie V. Beckwith & Jonathan M. Goodman & Weihsueh A. Chiu & Olivier Jolliet & Peter Fantke
- 1-17 Generalizable and scalable protein stability prediction with rewired protein generative models
by Ziang Li & Yunan Luo
- 1-17 Biomarkers of response to neoadjuvant palbociclib plus anastrozole in endocrine-resistant estrogen receptor-positive/HER2-negative breast cancer: a phase 2 trial
by Tim Kong & Alex Mabry & Maureen Highkin & Anthony Z. Wang & Jeremy Hoog & Zhanfang Guo & Adrian Gonzales-Gonzales & Shana Thomas & Yingduo Song & Feng Gao & Mateusz Opyrchal & Lindsay Peterson & Foluso Ademuyiwa & Julie Margenthaler & Rebecca Aft & Katherine Glover-Collins & Leslie Nehring & Yu Tao & Souzan Sanati & Ian S. Hagemann & Fouad Boulos & Matthew Holt & Li Ding & Wenge Zhu & Stephen T. Oh & Jianxin Wang & Agnieszka K. Witkiewicz & Erik S. Knudsen & Ron Bose & Jason D. Weber & Matthew Goetz & Donald Northfelt & Jingqin Luo & Cynthia X. Ma
- 1-17 CTCF couples long-range loop extrusion and diffusion to mediate a diverse Igκ repertoire
by Emma L. Bush & Brigette Berke-Reynolds & Kaitlyn M. Hutchins & Xinrui Yu & Jorge A. Colón-Rosado & Fujung Chang & John Curran & Jiaxin Yang & Liangliang Sun & Jianrong Wang & Yu Zhang
- 1-17 Autologous cell therapy with CD133+ bone marrow-derived stem cells for Asherman Syndrome: a phase 1/2 trial
by Xavier Santamaria & María Pardo-Figuerez & Javier González-Fernández & Sergi Querol & Luciano Rodríguez & David Valcárcel & Carla González & Estefanía Fernandez & Diego Amorós & Michael Robles & Sofia Granados-Aparici & Sheila Zuñiga & Francisco Martinez & Diana Valbuena & Carlos Gómez & Julio Herrero & Ramon Aurell & Juan José Torrent & Felipe Vilella & Petr Volkov & Francisco Raga & Rosa Noguera & Hugh S. Taylor & Carlos Simon
- 1-17 4EHP and NELF-E regulate physiological ATF4 induction and proteostasis in disease models of Drosophila
by Kristoffer Walsh & Hidetaka Katow & Hannah Junn & Deepika Vasudevan & Christoph Dieterich & Hyung Don Ryoo
- 1-17 Genetic Insights into Head-to-Body Ratios Via Deep Learning-Based Image Segmentation and Implications for Common Diseases
by Wei Shi & Shan-Shan Dong & Ren-Jie Zhu & Shi-Hao Tang & Jia-Hao Wang & Feng Jiang & Hao Wu & Yuan-Yuan Duan & Jing Guo & Kai Liu & Zheng-Qiang Li & Meng Li & Jianzhong Wang & Yan Guo & Tie-Lin Yang
- 1-17 A multi-ancestry genetic reference for the Quebec population
by Peyton McClelland & Georgette Femerling & Rose Laflamme & Alejandro Mejia-Garcia & Mohadese Sayahian Dehkordi & Hongyu Xiao & Alex Diaz-Papkovich & Justin Pelletier & Jean-Christophe Grenier & Ken Sin Lo & Luke Anderson-Trocmé & Justin Bellavance & Vincent Chapdelaine & Geneviève Gagnon & Annelie De Mori & Gerardo Martinez & Kristen Mohler & Thibault de Malliard & Catherine Labbé & Marjorie Labrecque & Alexandre Montpetit & Dan Spiegelman & Guy A. Rouleau & Jean-François Théroux & Hufeng Zhou & Simon L. Girard & Julie G. Hussin & Anne-Marie Laberge & Claude Bhérer & Martine Tetreault & Sarah A. Gagliano Taliun & Daniel Taliun & Simon Gravel & Guillaume Lettre
- 1-17 The photolyase/cryptochrome of Aspergillus nidulans senses oxidative stress and shuttles from nuclei to mitochondria
by Alexander Landmark & Tim Rudolf & Kevin Hundshammer & Jasmin Böhm & Kai Leister & Sylvia Erhardt & Reinhard Fischer
- 1-17 Infant gut anellovirus composition associates with early life factors and childhood atopic disease
by Ulrika Boulund & Jonathan Thorsen & Frej Larsen & Casper S. Poulsen & Michael Widdowson & Jie Jiang & Kaare Tranæs & Ling Deng & Morten Arendt Rasmussen & Bo Chawes & Klaus Bønnelykke & Dennis S. Nielsen & Shiraz A. Shah & Jakob Stokholm
- 1-17 Lithospheric models supported by the Caribbean and Levant examples help rethink transpression at plate boundaries
by Anthony Jourdon & Laetitia Le Pourhiet & Dave A. May & Manuel Pubellier & Alice-Agnes Gabriel
- 1-17 Parietal alpha frequency shapes own-body perception by modulating the temporal integration of bodily signals
by Mariano D’Angelo & Renzo C. Lanfranco & Marie Chancel & H. Henrik Ehrsson
- 1-17 Bacterial chromatin remodeling associated with transcription-induced domains at pathogenicity Islands
by Mounia Kortebi & Mickaël Bourge & Romain Le Bars & Erwin Van Dijk & Charles J. Dorman & Stéphanie Bury-Moné & Frédéric Boccard & Virginia S. Lioy
- 1-17 IGF2BPs directly regulate the noncanonical translation of toxic proteins from mutant FMR1 mRNA containing expanded CGG repeats
by Anna Baud & Damini Saha & Tomasz Skrzypczak & Izabela Broniarek & Daria Niewiadomska & Wojciech J. Szlachcic & Malgorzata Borowiak & Rajani Kanth Gudipati & Krzysztof Sobczak
- 1-17 The balance between stability and plasticity of the visual word form area in dyslexia
by Jamie L. Mitchell & Maya Yablonski & Hannah L. Stone & Mia Jimenez & Megumi E. Takada & Kenny A. Tang & Jasmine E. Tran & Clementine Chou & Jason D. Yeatman
- 1-17 WRN structural flexibility showcased through fragment-based lead discovery of inhibitors
by Rachel L. Palte & Mihir Mandal & Justyna Sikorska & Artjohn B. Villafania & Meredith M. Rickard & Robert J. Bauer & Alexei V. Buevich & Xiaomei Chai & Jiafang He & Zahid Hussain & Markus Koglin & Hannah B. MacDonald & My S. Mansueto & Klaus Maskos & Joey L. Methot & Jaclyn Robustelli & Aileen Soriano & Marcel J. Tauchert & Sriram Tyagarajan & Minjia Zhang & Daniel J. Klein & Jacqueline D. Hicks & David G. McLaren & Sandra B. Gabelli & Daniel F. Wyss
- 1-17 Structural determinants of non-covalent PPARγ inverse agonism and their therapeutic implications
by Kuang-Ting Kuo & Bilel Bdiri & Yuanjun He & Ruben D. Garcia-Ordonez & Daniel P. McDougal & Claudia Ruiz & Mi Ra Chang & Michael D. Cameron & John B. Bruning & Theodore M. Kamenecka & Patrick R. Griffin
- 1-17 Viral mimicry acts as a tumor suppressor in colitis
by Frederikke Larsen & Will Jeong & Daniel Schep & Hayley J. Good & Alice E. Shin & Liyue Zhang & Mathieu F. Derouet & Timothy C. Wang & Christina A. Castellani & Parisa Shooshtari & Samuel Asfaha
- 1-17 Comparative genomics analyses reveal genomic variation and evolutionary adaptation in Dendrobium orchids
by Bing-Jie Chen & Jie-Yu Wang & Shan-Ce Niu & Qi-Hang Chen & Xiao-Fang Chen & Pei-Ji Zheng & Yu-Min Liang & Kang-Li Li & Zhang-Zhen Zheng & Ying-Yi Liang & Cui-Li Zhang & Xue-Wei Zhao & Jun Li & Xin He & Lin-Ying Wang & Ye Huang & Qin-Yao Zheng & Meng-Meng Zhang & De-Qiang Chen & Cheng-Yuan Zhou & Meng-Yao Zeng & Zhuang Zhou & Ming-Zhong Huang & Zhuang Zhao & Dong-Hui Peng & Zi-Hao He & Long-Hai Zou & Bao-Cai Han & Wen-Chieh Tsai & Si-Ren Lan & Guo-Qiang Zhang & Zhong-Jian Liu & Qing Xu
- 1-17 A light-induced microprotein triggers regulated intramembrane proteolysis to promote photo-sensing in a pathogenic bacterium
by Dimitrios Manias & Ayushi Mishra & Jonathan D. Winkelman & Gong Chen & Sampriti Mukherjee
- 1-17 Tau condensation on DNA mediates microtubule attachment suggesting a mitotic role for centromere-localized tau
by Celine Park & Jaehun Jung & Yuri Hong & Haeun Yoo & Keunsang Yang & Jaehyeon Shin & Minsik Kim & Chan Lim & Ayoung Jeong & Seokyun Hong & Jun Young Baek & Sang-Hyun Rah & Chaelin Lee-Eom & Minseok Seo & Yoori Kim & Jae-Hyung Jeon & Jong-Bong Lee & Dong Soo Hwang & Min Ju Shon
- 1-17 Flavonoid-mediated bacterial spermidine biosynthesis enhances vitamin accumulation in tomato fruits
by Wenjiang Fu & Chenyu Sun & Bin Sun & Pengfei Li & Xinhua Ding & Qiao Guo & Jun Yuan & Hangxian Lai
- 1-17 Association-induced folding governs surrogate light chain and pre-B cell receptor core assembly
by Jasmin König & Natalia Catalina Sarmiento Alam & Ruiming He & Nicolas Blömeke & Olga Sieluzycka & Florian Rührnößl & Maximilian Riedl & Bernd Reif & Matthias J. Feige & Johannes Buchner
- 1-17 Near-infrared light-driven nanomotors-based microneedles for the active therapy of bacterial infected acne
by Ziwei Hu & Yuyang Gan & Yiying Song & Hanfeng Qin & Limeng Liu & Lu Liu & Fei Peng & Zhexiang Fan & Yingfeng Tu
- 1-17 Deep learning guided design of protease substrates
by Carmen Martin-Alonso & Sarah Alamdari & Tahoura S. Samad & Kevin K. Yang & Sangeeta N. Bhatia & Ava P. Amini
- 1-17 Discovery of a small molecule TLR3 agonist adjuvant
by Branden Lee & Danica Dong & Etsuro Nanishi & John Mark Awad & Kimia Z. Abedi & Yoshine Saito & Francesco Borriello & Soumik Barman & Byron Brook & Aisling Kelly & Manisha Menon & Constance Marques-Mourlet & Maansi V. Gupta & Ida Lister & Chiwoo Oh & Kevin Lyskawa & Morgan Goetz & Kristina Walker & Wing Ki Cheng & Spencer E. Brightman & Pankaj Sharma & Timothy R. O’Meara & Katherine Chew & Daniel Vieira & Kevin Ryff & Cali Sweitzer & Sanya Thomas & Simon D. van Haren & Matthew Pettengill & Hyuk-Soo Seo & Sirano Dhe-Paganon & Wei Zhang & Ofer Levy & David J. Dowling
- 1-17 Co-occurrence of diverse defense systems shapes complex microbe-virus relationships in deep-sea cold seeps
by Yingchun Han & Jing Liao & Chengpeng Li & Fengmin Xing & Jiaxue Peng & Xinyue Liu & Wentao Xie & Fabai Wu & Huahua Jian & Rui Cheng & Xiyang Dong
- 1-17 TMEM145 is a key stereociliary component in the link structures of outer hair cells and mediates the secretion of stereocilin and tubby
by Jae Won Roh & Kyung Seok Oh & Jiahn Lee & Yujin Choi & Soomin Kim & Ji Won Hong & Hei Yeun Koo & Haiyue Lin & Yelim Kim & Hogun Lew & Seung Hyun Jang & Hae-Sol Shin & Jiyeon Ohk & Hosung Jung & Kyoung Yul Seo & Jinsei Jung & Jinwoong Bok & Chul Hoon Kim & Heon Yung Gee
- 1-17 Tissue-specific and sex-biased glycoproteomic landscape of Schistosoma mansoni
by Xu Chen & Yanmin You & Wenxiao Liu & Shan Li & Cun Yi & Mengjie Gu & Wenjun Cheng & Gongwen Chen & Yuepeng Wang & Enlu Tang & Liming Wei & Haojie Lu & Wei Hu & Jipeng Wang
- 1-17 EPOP restricts PRC2.1 targeting to chromatin by directly modulating enzyme complex dimerization
by Lihu Gong & Xiuli Liu & Xin Yang & Ze Yu & Mohd Younus Bhat & Siming Chen & Andrew Lemoff & Chao Xing & Xin Liu
- 1-17 A comprehensive database for high-throughput identification of archaeal lipids using high-resolution mass spectrometry
by Fengfeng Zheng & Wenyong Yao & Wei He & Wan Zhang & Yufei Chen & Huahui Chen & Zhirui Zeng & Xiao-Lei Liu & Su Ding & Yanhong Zheng & Linan Huang & Yuanqing Zhu & Chuanlun Zhang
- 1-17 Mapping risks of health conditions in people with atopic eczema in English primary care and hospital data
by Julian Matthewman & Anna Schultze & Krishnan Bhaskaran & Amanda Roberts & Spiros Denaxas & Kathryn E. Mansfield & Sinéad M. Langan
- 1-17 Directional bias in interpersonal emotion perception
by Shir Genzer & Matan Rubin & Haran Sened & Eshkol Rafaeli & Kevin N. Ochsner & Noga Cohen & Anat Perry
- 1-17 Genome-scale spatial mapping of the Hodgkin lymphoma microenvironment identifies tumor cell survival factors
by Vignesh Shanmugam & Neriman Tokcan & Daniel Chafamo & Sean Sullivan & Mehdi Borji & Haley Martin & Gail Newton & Naeem Nadaf & Saoirse Hanbury & Irving Barrera & Dylan Cable & Jackson Weir & Orr Ashenberg & Geraldine Pinkus & Scott Rodig & Caroline Uhler & Evan Macosko & Margaret Shipp & Abner Louissaint Jr. & Fei Chen & Todd R. Golub
- 1-17 Local PI(4,5)P2 synthesis by septin-associated PIPKIγ isoforms controls centralspindlin association with the midbody during cytokinesis
by Giulia Russo & Nadja Hümpfer & Nina Jaensch & Steffen Restel & Christopher Schmied & Florian Heyd & Martin Lehmann & Helge Ewers & Volker Haucke & Michael Krauss
- 1-17 Lactate bridges mesangial cells to the differentiation of follicular helper T cells in lupus nephritis
by Mengdi Liu & Huiyan Ji & Jiaxin Lei & Ming Zheng & Lingyi Li & Xingyu Zhai & Hongmin Wang & Ting Liu & Qinghua Cao & Lin Xu & Zhenke Wen
- 1-17 Charge transfer in triphenylamine–tetrazine covalent organic frameworks for solar-driven hydrogen peroxide production
by Amin Zadehnazari & Florian Auras & Dimitrios Koumoulis & Alireza Abbaspourrad
- 1-17 A bio-adaptive physical hydrogel enables dynamic tissue engineering for tracheal reconstruction
by Hai Tang & Hanchen Wang & Weiyan Sun & Yi Chen & Ziyin Pan & Qingfeng Bai & Yaoben Wang & Weikang Lin & Yulong Hu & Lei Wang & Minglei Yang & Guofang Zhao & Lei Zhang & Yunlang She & Xuefei Hu & Kewen Lei & Jiandong Ding & Lin Yu & Chang Chen
- 1-17 Single cell proteomic analysis defines discrete neutrophil functional states in human glioblastoma
by Pranvera Sadiku & Alejandro J. Brenes & Rupert L. Mayer & Leila Reyes & Patricia Coelho & Gabi van Stralen & Ailiang Zhang & Manuel A. Sanchez-Garcia & Emily R. Watts & Imran Liaquat & Andrew J. M. Howden & Ikeoluwa Adekoya & Anuka Boldbaatar & Allan MacRaild & Sarah Risbridger & Gillian M. Morrison & Heather MacPherson & Caroline M. Bruce & Shonna Johnston & Robert Grecian & Fiona A. Murphy & Steven M. Pollard & Paul M. Brennan & Karl Mechtler & Sarah R. Walmsley
- 1-17 Rhomboid protease GlpG regulates type 1 pili quality control and virulence in pathogenic E. coli
by Jimmy Lu & Elena Arutyunova & Bridgette Hartley & Jonas Wong & Hyunjae Chung & Lanny Buchan & Heather Armstrong & Sadhna Phanse & Howard S. Young & Eytan Wine & Mohan Babu & Justin Chun & Wael Elhenawy & Olivier Julien & M. Joanne Lemieux
- 1-17 Epoxy-oxylipins direct monocyte fate in inflammatory resolution in humans
by Olivia V. Bracken & Parinaaz Jalali & James R. W. Glanville & Larrissa Benvenutti & Emma S. Chambers & Hugh Trahair & Madhur Motwani & Karen T. Feehan & Jamie G. Evans & Jhonatan de Souza Carvalho & Roel P. H. De Maeyer & Arne N. Akbar & Fred B. Lih & Darryl C. Zeldin & David Bishop-Bailey & Matthew L. Edin & Derek W. Gilroy
- 1-17 Integrated stress response inhibition prolongs the lifespan of a Pelizaeus-Merzbacher disease mouse model by increasing oligodendrocyte survival
by Yanan Chen & Rejani B. Kunjamma & Karin Lin & Li Kai & Maria Dima & Kody Bruce & Ian Steckler & Young Hyun Che & Jason Chan-Zervas & Jaime Eugenin von Bernhardi & Caitlin Connelly & Sude Ece & Grace Newell & Dwight E. Bergles & Carmela Sidrauski & Brian Popko
- 1-17 Chronically implantable μLED arrays for optogenetic cortical surface stimulation in mice
by Ryan Greer & Antonin Verdier & Emma Butt & Yunzhou Cheng & Ella Callas & Niall McAlinden & Alicia Aniorte & Eya Mabrouk Kakaouia & Magdalena Pereyra & Martin D. Dawson & Brice Bathellier & Keith Mathieson
- 1-17 Structural basis of specific lysine transport by Pseudomonas aeruginosa permease LysP
by Deniz Bicer & Rei Matsuoka & Aurélien F. A. Moumbock & Preethi Sukumar & Albert Suades & Harish Cheruvara & Andrew Quigley & David Drew & Els Pardon & Jan Steyaert & Peter J. F. Henderson & Martin Caffrey & Julia J. Griese & Emmanuel Nji
- 1-17 Small molecule splicing modulators that disrupt O-GlcNAc homeostasis
by Steven S. Cheng & Alison C. Mody & Amedeo Vetere & Ashwin Govindan & Yewon Lee & Danielle E. Khost & Rohan Narayan & Timothy B. Sackton & Nicholas K. Conrad & Bridget K. Wagner & Christina M. Woo
- 1-17 Multilayered regulation of TORC1 signaling by Ait1, Gcn2, and SEAC/GATOR during nitrogen limitation and starvation
by Cristina M. Padilla & Jeaho Lim & Austin A. Lipinski & Paul R. Langlais & Andrew P. Capaldi
- 1-17 A versatile platform for sequential glyco-, phospho-, and proteomics with multi-PTMs integration
by Xuefang Dong & Fangfang Xiong & Guangzhu Du & Yunfei Yang & Cheng Chen & Yun Cui & Xinlian Ding & Xiuling Li & Yidong Shen & Xinmiao Liang
- 1-17 Conflicting entropy-driven zwitterionic dry polymer electrolytes for scalable high-energy all-solid-state batteries
by Kyeong-Seok Oh & Ji Eun Lee & Jong Chan Shin & Dokyung Kim & Won-Yeong Kim & Imanuel Kristanto & Dong-Yeob Han & Soohyoung Lee & Eun Ji Shim & Seong-Hun Lee & Hyunseok Moon & Sejung Oh & Sohee Kim & Tae Joo Shin & Kyuwook Ihm & Young Joo Lee & Minjae Lee & Sang Kyu Kwak & Sang-Young Lee
- 1-17 The focal adhesion kinases regulate leptin action and the weight reducing effect of HDAC6 inhibition
by Colleen K. Hadley & Luca Galgano & Yijun Gui & Antonio M. Carvalho da Silva & Danielle T. Porter & Yanan Wu & Yuanting Lai & Mauro Torti & Işın Çakır
- 1-17 Local therapeutic platform prevents postsurgical GBM recurrence by diminishing GICs and reshaping immunosuppressive microenvironment
by Mengxi Zhu & Mengting Yang & Rui Li & Xiwen Hu & Jiaxuan Chen & Limin Xu & Sunhui Chen & Tao Li & Jianxin Wang & Bin Zheng & Huining He
- 1-17 Boron neutron capture therapy preserves immune cells and induces robust anti-tumour immunity in preclinical mouse model
by Qi Sun & Yanping Zhao & Simiao Qiao & Kexuan Wang & Chuanjie Lu & Zizhu Zhang & Zhibin Guo & Zexuan Ding & Chunhong Wang & Jiyuan Li & Tong Liu & Zexian Zeng & Zhibo Liu
- 1-17 mGluR4–NPDC1 complex mediates α-synuclein fibril-induced neurodegeneration
by Azucena Perez-Canamas & Mingming Chen & Leire Almandoz-Gil & Nabab Khan & Si Jie Tang & Allyson Ho & Erik C. Gunther & Stephen M. Strittmatter
- 1-17 Linguistic features of AI mis/disinformation and the detection limits of LLMs
by Yulong Ma & Xinsheng Zhang & Jinge Ren & Runzhou Wang & Minghu Wang & Yang Chen
- 1-17 Crowdsourced biodiversity monitoring fills gaps in global plant trait mapping
by Daniel Lusk & Sophie Wolf & Daria Svidzinska & Carsten F. Dormann & Jens Kattge & Helge Bruelheide & Francesco Maria Sabatini & Gabriella Damasceno & Álvaro Moreno Martínez & Cyrille Violle & Daniel Hending & Georg J. A. Hähn & Solana Tabeni & Shyam Phartyal & Fernando Gonçalves & Holger Kreft & Marco Schmidt & Han Chen & Behlül Güler & Jiri Dolezal & Remigiusz Pielech & Anaclara Guido & Ciara Dwyer & Francesca Napoleone & Jacob Willie & André Luís Gasper & Manuel J. Macía & Milan Chytry & Jonathan Lenoir & Dinesh Thakur & Jürgen Dengler & Sebastian Świerszcz & Jan Altman & Ladislav Mucina & Ashish N. Nerlekar & Kaoru Kakinuma & Pravin Rawat & Zvjezdana Stančić & Riccardo Testolin & Mohamed Z. Hatim & Flávio Rodrigues & Jürgen Homeier & Marcia C. M. Marques & James K. McCarthy & M. A. El-Sheikh & Kirill Korznikov & Kilian Gerberding & Teja Kattenborn
- 1-17 Implementing N-terminomics and machine learning to probe Nt-arginylation
by Shinyeong Ju & Laxman Nawale & Seonjeong Lee & Jung Gi Kim & Hankyul Lee & Narae Park & Dong Hyun Kim & Hyunjoo Cha-Molstad & Cheolju Lee
- 1-17 IL-33 expands plasma cells, disrupts germinal centers, and increases autoantibody production in mice
by Eva Conde & Seblewongel Asrat & Andrea Vecchione & Kaitlyn Gayvert & Paulina Pedraza & Carley Tasker & Sharon Huang & Dmitry Yarilin & Dylan Birchard & Li-Hong Ben & Wei Keat Lim & Andrew J. Murphy & Matthew A. Sleeman & Andre Limnander & Jamie M. Orengo
- 1-17 Vibrissae-inspired vision-based magnetic-actuated whisker
by Zhixian Hu & Yi Cheng & Juan Wachs & Yu She
- 1-17 Medicago super-pangenome reveals adaptive advantages and evolutionary constraints in autotetraploid alfalfa
by Fan Zhang & Chunxue Wei & Xiaoya Shi & Shuo Cao & Xiaodong Xu & Zhiyao Ma & Yanling Peng & Rida Arshad & Hui Xue & Zhen Zhang & Wei Zhang & Yanshuai Xu & Yang Dong & Lianzhu Zhou & Xuejing Cao & Mengrui Du & Xu Wang & Zhiwu Zhang & Ruicai Long & Junmei Kang & Yongfeng Zhou & Qingchuan Yang
- 1-17 Cosmopolitan marine bacteria facilitate a vast phytoplankton-derived sulfonate-based carbon flow through sulfoquinovosidases
by Xiaoyi Ma & Huanyu Wang & Changjie Dong & Le Liu & Xuanyun Qiu & Xiaofeng Chen & Quanrui Chen & Liang Wang & Yao Zhang & Nianzhi Jiao & Spencer J. Williams & Kai Tang
- 1-17 Structure of SHOC2-KRAS-PP1C complex reveals RAS isoform-specific determinants and insights into targeting complex assembly by RAS inhibitors
by Daniel A. Bonsor & Lorenzo I. Finci & Jacob R. Potter & Lucy C. Young & Vanessa E. Wall & Ruby Goldstein de Salazar & Katie R. Geis & Tyler Stephens & Joseph Finney & Dwight V. Nissley & Frank McCormick & Dhirendra K. Simanshu
- 1-17 The glymphatic system clears amyloid beta and tau from brain to plasma in humans
by Paul Dagum & Donald L. Elbert & Laurent Giovangrandi & Tarandeep Singh & Venky V. Venkatesh & Alejandro Corbellini & Robert M. Kaplan & Swati Rane Levendovszky & Elizabeth Ludington & Kevin Yarasheski & Jeffrey Lowenkron & Carla VandeWeerd & Miranda M. Lim & Jeffrey J. Iliff
- 1-17 αPD-1-conjugated acid-cleavable nanodrugs overcomes cellular immunotherapy barriers in pancreatic tumors
by Ziqi Gan & Jing Huang & Shuting Duan & Minzhao Lin & Shaohui Deng & Sicong Huang & Jiachen Wang & Xintao Shuai & Zecong Xiao
- 1-17 Longitudinal plasma proteomic signatures of elite and viremic spontaneous HIV controllers
by Nadira Vadaq & Albert L. Groenendijk & Jéssica C. dos Santos & Kavita Mehta & Ferdinand W.N.M. Wit & Wilhelm A. J. W. Vos & Martinus J. T. Blaauw & Louise E. van Eekeren & Laurens Lambrechts & Sofie Rutsaert & Erni J. Nelwan & Cheng-Jian Xu & Leo A. B. Joosten & Quirijn de Mast & Vasiliki Matzaraki & Jan van Lunzen & Casper Rokx & Annelies Verbon & Mihai G. Netea & Linos Vandekerckhove & André J. A. M. van der Ven
- 1-17 Colonic spatial single-cell proteomics and murine models link mitochondrial dysfunction to dimeric IgA-secreting plasma cell deficiency in Crohn’s disease
by Annika Raschdorf & Larissa Nogueira de Almeida & Philipp Solbach & Martha M. Kirstein & Jens U. Marquardt & Franziska Schmelter & Ulrich L. Günther & Heidi Schlichting & Maren Hicken & Lea Christiansen & Miriam Wiestler & Hauke C. Tews & Dominik Bettenworth & Matthias Peipp & Thomas Valerius & Mohab Ragab & Thorben Sauer & Timo Gemoll & Marc Ehlers & Philip Rosenstiel & Rudolf A. Manz & Axel Künstner & Hauke Busch & Christian Sina & Stefanie Derer
- 1-17 Central amygdala single-nucleus atlas reveals chromatin and gene transcription dynamics in human alcohol use disorder
by Che Yu Lee & Ahyeon Hwang & Delaney McRiley & Jaywon Lee & Genevieve Thibodeau & Catharine Duman & Xiangyu Zhang & Mario Skarica & Jensine Coudriet & Siwei Xu & Rosemarie Terwilliger & Alexa-Nicole Sliby & Jiawei Wang & Tuan Nguyen & Yujing Liu & Hongyu Li & Yi Dai & Ziheng Duan & Yutong Lei & Yingxin Lin & Jill R. Glausier & David A. Lewis & Joel Gelernter & Paul E. Holtzheimer & Ke Xu & Hang Zhou & Hongyu Zhao & Summer L. Thompson & John H. Krystal & Alicia Che & Jane R. Taylor & Jing Zhang & Matthew J. Girgenti
- 1-17 SARS-CoV-2 EndoU-ribonuclease regulates RNA recombination and impacts viral fitness
by Yiyang Zhou & Yani P. Ahearn & Kumari G. Lokugamage & Angelica L. Morgan & R. Elias Alvarado & Leah K. Estes & William M. Meyers & Alyssa M. McLeland & Jordan T. Murray & Joseph R. Rouse & Meenakshi Kar & Mehul S. Suthar & David H. Walker & Bryan A. Johnson & Andrew L. Routh & Vineet D. Menachery
- 1-17 EP300 deficiency leads to chronic replication stress mediated by defective replication fork protection
by Angelica Barreto-Galvez & Mrunmai Niljikar & Julia Elizabeth Gagliardi & Carolina Plasencia Guzman & Ranran Zhang & Vasudha Kumar & Aastha Juwarwala & Archana Pradeep & Ankit Saxena & Cristina Montagna & Priya Mittal & Jeannine Gerhardt & Bing Xia & Jian Cao & Keisuke Kataoka & Adam David Durbin & Jun Qi & B. Hilda Ye & Advaitha Madireddy
- 1-17 The PIK3CA/AKT pathway drives therapy resistance in rhabdomyosarcoma
by Qiqi Yang & Yueyang Wang & Luis A. Corchete Sanchez & Sabateeshan Mathavarajah & Qian Qin & Yun Wei & Eric Alpert & Lauren Whelton & Priyanshu Sharma & Stephanie Strom & Ilyas Oultache & A. John Iafrate & Luca Pinello & Esther Rheinbay & Chuan Yan & David M. Langenau
- 1-17 De novo variants in the splicing factor gene SF3B1 are associated with neurodevelopmental disorders
by Kevin Uguen & Tiffany Bergot & Marie-Pier Scott-Boyer & Solène Chapalain & Camille Desdouets & Séverine Commet & Changlian Zhu & Yiran Xu & Yangong Wang & Tony Roscioli & Frederic Tran-Mau-Them & Laurence Faivre & Julien Maraval & Julian Delanne & Anne-Sophie Denommé-Pichon & Antonio Vitobello & Céline Jost & Marc Planes & Susan Hiatt & Patricia Wheeler & Claudia Gonzaga-Jauregui & Heng Wang & Baozhong Xin & Valerie Sency & Michael C. Kruer & Somayeh Bakhtiari & Patrick Sulem & Cynthia Curry & Trine Prescott & Gertrud Strobl-Wildemann & Theresa Brunet & Martine Doco Fenzy & Thomas Courtin & Céline Poirsier & Trine Bjørg Hammer & Christina D. Fenger & Melissa MacPherson & Kosuke Izumi & Jacqueline Leonard & Dong Li & Elaine H. Zackai & Ian A. Glass & Scott Ward & Philippe M. Campeau & Maria Carla Hermida Borroto & Laurence Le Moigno & Hilde Van Esch & Liesbeth De Waele & Daniel G. Calame & James R. Lupski & Giulia Barcia & Cristina Peduto & Pauline Planté-Bordeneuve & Lucie Dupuis & Roberto Mendoza-Londono & Dimitri J. Stavropoulos & Jennifer Gillibert-Duplantier & Thomas Besnard & Laura Do Souto Ferreira & Benjamin Cogné & Stéphane Bézieau & Arnaud Droit & Laurent Corcos & Eric Lippert & Claude Férec & Sebastien Küry & Delphine G. Bernard
- 1-17 Explainable AI-based analysis of human pancreas sections identifies traits of type 2 diabetes
by Lukas Klein & Sebastian Ziegler & Felicia Gerst & Yanni Morgenroth & Karol Gotkowski & Eyke Schöniger & Martin Heni & Nicole Kipke & Daniela Friedland & Annika Seiler & Ellen Geibelt & Hajime Yamazaki & Hans-Ulrich Häring & Silvia Wagner & Silvio Nadalin & Alfred Königsrainer & Andre L. Mihaljevic & Daniel Hartmann & Falko Fend & Daniela Aust & Jürgen Weitz & Reiner Jumpertz-von Schwartzenberg & Marius Distler & Klaus Maier-Hein & Andreas L. Birkenfeld & Susanne Ullrich & Paul F. Jäger & Fabian Isensee & Michele Solimena & Robert Wagner
- 1-17 Accumbal calcium-permeable AMPA receptors orchestrate neuronal ensembles underlying social attachment
by Mostafa M. El-Kalliny & J. Keenan Kushner & William M. Sheeran & Olivia E. Neilly & Kelly E. Winther & Liza E. Brusman & Michael A. Kelberman & Charles A. Hoeffer & Zoe R. Donaldson
- 1-17 Mitochondrial components secretion in extracellular vesicles promotes alveolar epithelial mitochondrial quality control
by Bowen Liu & Yue Han & Yuan Jin & Meng Ye & Zeliang Yang & Jingyi Yang & Minglu Zhu & Xuyang Zhao & Yan Jin & Yuxin Yin
- 1-18 Sirt6 deficiency in mast cells promotes adipose fibroinflammation in obesity through galectin-3 signaling
by Mi-Young Song & Yong Geun Jeon & Jae Do Yang & Young Jae Moon & Jae Bum Kim & Eun Ju Bae & Byung-Hyun Park
- 1-18 Thrombopoietin increases susceptibility for EVI1 + KMT2A-MLLT3-driven AML expressing stem cell genes linked to poor outcome
by Hugues-Étienne Châtel-Soulet & Sabine Juge & Ana Luisa Pereira & Jonathan Seguin & Athimed El Taher & Federica Valigi & Zivojin Jevtic & Rathick Sivalingam & Frederik Otzen Bagger & Paul Büschl & Marwa Almosailleakh & Alexander Tzankov & Wei Tong & Mineo Kurokawa & César Nombela Arrieta & Juerg Schwaller
- 1-18 From TDP-43/RNA complex formation to disease-linked TDP-43 aggregation through a structural and cellular approach
by Yitian Feng & Vandana Joshi & Serhii Pankivskyi & Marie-Jeanne Clément & Juan Carlos Rengifo-Gonzalez & Aurélien Thureau & David Pastré & Ahmed Bouhss
- 1-18 A corticospinal signature for interindividual pain sensitivity
by Xiao-Min Lin & Ling-Fei Guo & Bing Ni & Jiu-Quan Zhang & Xiao-Shuo Zhang & Li-Bo Zhang & Zhao-Xing Wei & Yun-Yun Duan & Li Hu & Ming Zhang & Jing-Yi Zhang & Min Shao & Zai-Ying Jiang & Yun-Jian Huang & Ji-Xin Liu & Li-Ming Cheng & Jonathan C. W. Brooks & Tor D. Wager & Irene Tracey & Ya-Ou Liu & Ya-Zhuo Kong
- 1-18 Methionine restriction alleviates kidney fibrosis through epigenetic repression of the TGF-β-Smad3-Hoxc8/P-TEFb axis
by Yunjing Liu & Zhiheng Liu & Lijun Liu & Yongxuan Su & Jiayuan Chen & Bo Qing & Chen Tang & Ziling Zhang & Rongjie Ji & Xinyi Cao & Ting Wang & Junya Jia & Yupeng Chen & Lirong Zhang
- 1-18 Adaptive compression framework for giga-pixel whole slide images
by Jonghyun Lee & Lina Takemaru & D. M. Bappy & Ye Sul Jeong & Won-Ki Jeong & Derek Oldridge & Dokyoon Kim & Sangjeong Ahn & Sung Hak Lee
- 1-18 A B cell-IgA-epithelial axis enhances antitumor immunity and improves outcome in HPV-associated penile squamous cell carcinoma
by Tao Tao & Lianbang Zhu & Deyun Shen & Jiayang Zhang & Panrui Zhang & Zhixi Gu & Dan Cao & Jun Xiao & Wen Pan
- 1-18 INSM1 governs a neuronal progenitor state that drives glioblastoma in a human stem cell model
by Patrick A. DeSouza & Matthew Ishahak & Xuan Qu & Colin McCornack & Devi Annamalai & Diane D. Mao & Rajanikanth Vangipurapu & Yiwei Fu & Alexandre T. Vessoni & Ryan T. Cleary & Rowland H. Han & Punn Augsornworawat & Timothy Woodiwiss & Darby Agovino & Braxton Sizemore & Jessica Kline & Maryam Borhani-Haghighi & Hao Chen & Sangami Pugazenthi & Hiroko Yano & Ting Wang & Luis F. Z. Batista & Jeffrey R. Millman & Albert H. Kim
- 1-18 A programmable ribozyme for RNA signal transduction
by Mandy Yu Theng Lim & Chermaine Tan & Charannya Sozheesvari Subhramanyam & Shi Jie Teo & Louis DeFalco & Samuel Kevin Pasaribu & Chong Hui Koh & Dheeraj Rayamajhi & Jieying Chi & Shengnan Li & Keng Boon Wee & Sudipto Roy & Roland G. Huber & Sherry Shiying Aw
- 1-18 Biguanide-functionalized peptide mimics effectively combat drug-resistant ESKAPE pathogens and meningitis
by Weinan Jiang & Min Zhou & Kang Chen & Ximian Xiao & Jia Shi & Haodong Zhang & Jiayang Xie & Sheng Chen & Minzhang Chen & Zihao Cong & Longqiang Liu & Yueming Wu & Runhui Liu
- 1-18 Mutant KRAS vaccine with dual checkpoint blockade in resected pancreatic cancer: a phase I trial
by Amanda L. Huff & S. Daniel Haldar & Alexander A. Gergis & Hejia Henry Wang & Ludmila Danilova & Thatcher Heumann & Maureen Berg & Yuxuan Wang & Lalitya Andaloori & Alexei Hernandez & Gabriella Longway & Benjamin Barrett & Zirui Zhu & Emily Davis-Marcisak & Christopher Thoburn & James Leatherman & Sarah Mitchell & Jae W. Lee & Daniel H. Shu & Maximillian F. Konig & Brian J. Mog & Janelle Montagne & Erin M. Coyne & Katherine Bever & Marina Baretti & Mark Yarchoan & Robert A. Anders & Luciane T. Kagohara & Daniel Laheru & Amy M. Thomas & Jennifer Durham & Julie M. Nauroth & Jiayun Lu & Hao Wang & Elana J. Fertig & Won Jin Ho & Nilofer S. Azad & Elizabeth M. Jaffee & Neeha Zaidi
- 1-18 Intrinsic resistance to RAS inhibitors is driven by dysregulation of KRAS degradation
by Tonci Ivanisevic & Yan Ma & Emiel Van Boxel & Wout Magits & Benoit Lechat & Zeynep Koçberber & Phillipp Willnow & Sarah-Maria Fendt & Greetje Vande Velde & Raj Sewduth & Anna A Sablina
- 1-18 APOBEC3 promotes squamous differentiation via IL-1A/AP-1 signaling
by Michael S. Sturdivant & Andrew S. Truong & Mi Zhou & Elliott D. Toomer & Wolfgang Beckabir & John Raupp & Ujjawal Manocha & Ibardo A. Zambrano & Hung-Jui Tan & Marc A. Bjurlin & Angela B. Smith & Tracy L. Rose & Matthew I. Milowsky & Sara E. Wobker & Kathryn H. Gessner & Jeffrey S. Damrauer & William Y. Kim
- 1-18 Single-cell RNA sequencing reveals a quiescence-senescence continuum and distinct senotypes following chemotherapy
by Brianna Fernandez & Victor J. Passanisi & Humza M. Ashraf & Sabrina L. Spencer
- 1-18 The non-catalytic DNA polymerase ε subunit is an NPF motif recognition protein
by Salla Keskitalo & Boglarka Zambo & Dicle Malaymar Pinar & Antti Tuhkala & Kari Salokas & Tanja Turunen & Norbert Deutsch & Norman Davey & Zsuzsanna Dosztányi & Markku Varjosalo & Gergo Gogl
- 1-18 Decreased scleral Wnt5ahi fibroblasts exacerbate myopia progression by disrupting extracellular matrix homeostasis in mice
by He Zhu & Wei Chen & Xuemei Ling & Shiming Jiao & Le Yu & Huihui Liu & Mengyi Ding & Fan Zhang & Yixin Zhou & Yulu Pan & Zhonglou Zhou & Jia Qu & Fei Zhao & Fuxin Zhao & Xiangtian Zhou
- 1-18 Intergeneric chromosomal transfer in yeast results in improved phenotypes and widespread transcriptional responses
by Yilin Lyu & Yi Shi & Kunfeng Song & Jungang Zhou & Hao Chen & Xueying C. Li & Yao Yu & Hong Lu
- 1-18 Metabolic support protects mucosa from ferroptosis in radiation-induced mucositis
by Weiwei Yu & Kai Jiao & Kaiyan Wang & Xiang Li & Qianqian Wan & Wen Qin & Xinyi Hao & Meichen Wan & Yuxuan Ma & Jiao Wu & Qing Liu & Mei Shi & Conrado Aparicio & Franklin Tay & Lina Niu
- 1-18 Drug and single-cell gene expression integration identifies sensitive and resistant glioblastoma cell populations
by Robert K. Suter & Anna M. Jermakowicz & Rithvik Veeramachaneni & Matthew D’Antuono & Longwei Zhang & Rishika Chowdary & Simon Kaeppeli & Madison Sharp & Pravallika Palwai & Vasileios Stathias & Grace Baker & Luz Ruiz & Winston Walters & Maria Cepero & Danielle Burgenske & Edward B. Reilly & Anatol Oleksijew & Mark G. Anderson & Sion Ll. Williams & Michael E. Ivan & Ricardo J. Komotar & Macarena I. De La Fuente & Gregory Stein & Alexandre Wojcinski & Santosh Kesari & Jann N. Sarkaria & Stephan C. Schürer & Nagi G. Ayad
- 1-18 Fragment-based discovery enables direct targeting of the melanoma oncogene MITF
by Deborah Castelletti & Jürgen Hinrichs & Goran Malojčić & Fei Ji & Aurore Desplat & Bryn Reimer & Christelle Henry & Kathryn A. Porter & Fanny Mermet-Meillon & Markus Wartmann & Emmanuelle Wirth & Cécile Delmas & César Fernández & Philipp H. O. Mayer & Niko Schmiedeberg & Simone Plattner & Jvan Brun & Stephan Kläusler & Jessica Kurmann & Kelly Yan & John Fuller & Fanny Schaeffer & Danilo Maddalo & Marc Altorfer & Nikoletta Piperidou & Nicolas Pautrieux & Frederic Baysang & Markus Kaufmann & Amanda Cobos-Correa & Rainer Wilcken & Martin Renatus & Anna Vulpetti & Wolfgang Jahnke
- 1-18 Cross-species evidence for a developmental origin of adult hypersomnia with loss of synaptic adhesion molecules beat-Ia/CADM2
by Kyla Mace & Amber Zimmerman & Alessandra Chesi & Fusun Doldur-Balli & Hayle Kim & Erika Almeraya del Valle & Jeffrey B. Rosa & Allan I. Pack & Struan F. A. Grant & Matthew S. Kayser
- 1-18 The UFL1-AKT positive feedback loop promotes breast cancer progression by enhancing lipid synthesis
by Fei Meng & Yating Du & Junjie Liang & Huiyan Li & Jingjing Wang & Kexin Tang & Ruixue Kong & Huanran Sun & Tingting Yin & Junru Qin & Xiaomeng Yang & Changliang Shan & Min Liu & Guiwen Yang & Jichun Zhang & Yijie Wang & Jun Zhou & Yan Chen
- 1-18 Decrypting spatiotemporal code of human endometrial receptivity
by Yang Liu & Yang Wang & Leilei Zhang & Yedong Tang & Yetao Hong & Meng Liu & Mengyuan Wang & Ya Sun & Xiaoyue Shen & Jie Mei & Min Wu & Na Kong & Shuangbo Kong & Haili Bao & Wenbo Deng & Guijun Yan & Haibin Wang & Haixiang Sun
- 1-18 The interconnected wirings between medial prefrontal cortex and claustrum and their governing roles in the methamphetamine reward memory in male mice
by Yuhong He & Ziheng Zhao & Yang Liu & Quying Feng & Sijia Wang & Wenzhong Wu & Hee Young Kim & Yu Fan & Xiaowei Guan
- 1-18 Dynamins maintain nuclear envelope homeostasis and genome stability
by Célia Aveleira & Thibaud Martial & Loïc Carrique & Rita Gaspar & Ana Caulino-Rocha & Izaak Myatt & Franz Wendler & Pauline Lascaux & Misha Le Claire & James Bancroft & Carl Smythe & Kristijan Ramadan & Nuno Raimundo & Ira Milosevic
- 1-18 Machine learning-assisted kinetic matching model for rational electrode design in aqueous zinc-ion batteries
by Qian Xie & Yurong You & Dingshuo Qiao & Huan Xia & Hanning Zhang & Song-Zhu Kure-Chu & Tomasz Wejrzanowski & Tao Shui & Wei Zhang & ZhengMing Sun
- 1-18 CellScope: high-performance cell atlas workflow with tree-structured representation
by Bingjie Li & Runyu Lin & Tianhao Ni & Guanao Yan & Mannix Burns & Jingyi Jessica Li & Zhigang Yao
- 1-18 Bioorthogonal optimized virus immuno-nanomedicine (BOVIN)
by Wenchang Peng & Yajing Du & Luna Cui & Yi Xiao & Lavonda Li & Lijie Yan & Yun Gu & Lulu Zhang & Bowen Li & Zhiyun Wang & Hua Wang & Xinyu Dai & Yue Teng & Tao Wang & Bin Zheng & Xingcai Zhang
- 1-18 Lypd6b depletion promotes CD8+ T cell-mediated anti-tumor immunity via metabolic reprogramming in colorectal cancer
by Ting Liu & Fanxin Zeng & Zuyin Li & Leirong Cheng & Xuanxuan Yan & Haiqiang Chen & Qin Liu & Xue Li & Zhao Li & Jiaheng Yao & Dan Xu & Zhinan Chen & Fengchao Wang & Jun Wang & Jinhua Zhang
- 1-18 Affiliative behaviours regulate allostasis development and shape biobehavioural trajectories in horses
by Mathilde Valenchon & Fabrice Reigner & Gaëlle Lefort & Hans Adriaensen & Amandine Gesbert & Philippe Barrière & Yvan Gaude & Frederic Elleboudt & Isabelle Lévy & Camille Ducluzeau & Joëlle Dupont & Anne-Lyse Lainé & Ivy Uszynski & Hugues Dardente & Cyril Poupon & Léa Lansade & Ludovic Calandreau & Matthieu Keller & David André Barrière
- 1-18 The genetic architecture of brainstem structures
by Hui Xue & Jilian Fu & Zuojun Geng & Jingliang Cheng & Meiyun Wang & Longjiang Zhang & Guangbin Cui & Yongqiang Yu & Weihua Liao & Hui Zhang & Bo Gao & Xiaojun Xu & Tong Han & Zhenwei Yao & Quan Zhang & Wen Qin & Feng Liu & Meng Liang & Sijia Wang & Qiang Xu & Jiayuan Xu & Caihong Wang & Nana Liu & Yuan Ji & Peng Zhang & Wei Li & Wei Wei & Dapeng Shi & Su Lui & Zhihan Yan & Feng Chen & Jing Zhang & Wen Shen & Yanwei Miao & Dawei Wang & Jia-Hong Gao & Yunjun Yang & Kai Xu & Junfang Xian & Bing Zhang & Xiaochu Zhang & Xi-Nian Zuo & Mulin Jun Li & Zhaoxiang Ye & Shijun Qiu & Wenzhen Zhu & Chunshui Yu
- 1-18 Covalent modification of a glutamic acid inspired by HaloTag technology
by Ruirui Zhang & Jie Liu & Raphael Gasper & Anke Unger & Farnusch Kaschani & Markus Kaiser & Petra Janning & Herbert Waldmann
- 1-18 The E3 ligases Itch and WWP2 regulate autoimmune neuroinflammation by controlling TH2 to TH17 cell conversion via interleukin-4-STAT5 axis in mice
by Mei Zhao & Chao Zhang & Xin Zhang & Qingdian Mu & Qian Li & Yun-Cai Liu
- 1-18 Light-induced analgesia provides a drug-free optical method for pain relief via activation of TRAAK k+ channels
by Marion Bied & Arnaud Landra-Willm & Anne Amandine Chassot & Edward Francisco Mendez-Otalvaro & Benjamin Sueur & Kilian Roßmann & Elvira de la Peña & Pascal Fossat & Stephen J. Tucker & Jacques Noël & Wojciech Kopec & Felix Viana & Johannes Broichhagen & Eric Boué-Grabot & Guillaume Sandoz
- 1-18 IDH2 lactylation promotes angiogenesis in murine diabetic myocardial infarction via blocking Cav1-eNOS interaction
by Guangyao Zang & Siting Xu & Zhen Sun & Lili Zhang & Yongjiang Qian & Haipeng Yao & Lihua Li & Zhongqun Wang
- 1-18 SNORA49 negatively regulates self-renewal of liver cancer stem cells and hepatocarcinogenesis via suppressing SOX9 transcription
by Zhibin Yi & Ziheng Zhou & Yang Gu & Yuwei Xu & Ziqi Xiao & Zhen Xiong & Jianyi Wang & Hui Guo & Ying Du & Yun Chen & Zusen Fan
- 1-18 Lymphatic–stem cell crosstalk promotes tendon regeneration via Notch1–Srebp2–mediated cholesterol metabolism
by Liujing Chen & Meilian Cai & Shuai Lin & Mingzhao Li & Zilu Zhu & Han Zhang & Hu Zhao & Chun Xu & Ruili Yang
- 1-18 NCOA1 is a gatekeeper of the sexually dimorphic thermogenic activity of white adipose tissue
by Mounia Tannour-Louet & Didier F. Pisani & Hichem Bouguerra & Alycia Zedda & Marine Bourcier & Noura Lamghari & Nadine Gautier & Benoit Chaput & Elodie Riant & Anne Bouloumié & Emilie Montastier & Nathalie Viguerie & Dominique Langin & Ez-Zoubir Amri & Pierre Gourdy & Jean-François Tanti & Mireille Cormont & Jean-François Louet
- 1-18 Computationally-designed aptamers targeting RAD51-BRCA2 interaction impair homologous recombination and induce synthetic lethality
by Giulia Milordini & Elsa Zacco & Mirco Masi & Alexandros Armaos & Francesco Di Palma & Michele Oneto & Martina Gilodi & Jakob Rupert & Laura Broglia & Giulia Varignani & Marco Scotto & Roberto Marotta & Stefania Girotto & Andrea Cavalli & Gian Gaetano Tartaglia
- 1-18 BPTF regulates androgen receptor activity by enhancing chromatin accessibility and stabilizing the AR-FOXA1 interaction
by Hee-Young Jeon & Sudeep Khadka & Majid Pornour & Hyunju Ryu & Hegang Chen & Arif Hussain & Hung-Ming Lam & Eva Corey & Htoo Zarni Oo & Martin Gleave & Xiaofang Che & Christopher Barbieri & Jianfei Qi
- 1-18 Staphylococcus aureus fatty acid metabolism governs saeRS-mediated aggregation in joint infections
by Jinlong Yu & Mingzhang Li & Changming Wang & Musha Hamushan & Yujie Hu & Yi Yang & Feng Jiang & Jireng Yan & Boyong Wang & Xiaohua Chen & Jin Tang & Geyong Guo & Pei Han & Hao Shen
- 1-18 Biallelic variants in CELSR1 cause brain malformations, neurodevelopmental disorders and epilepsy in humans
by Claudia M. Bonardi & Rikke S. Møller & Nuria Ruiz-Reig & Guoliang Chai & Camilla G. Madsen & Allan Bayat & Trine B. Hammer & Christina D. Fenger & Elena Gardella & Pawel Gawlinski & Mateusz Dawidziuk & Wojciech Wiszniewski & Monika Bekiesinska-Figatowska & Sara Cabet & Massimiliano Rossi & Gaetan Lesca & Evan Gouy & Birgit Jepsen & Tomasz S. Mieszczanek & Rossana Sanchez Russo & Eileen E. Barr & Katrin Õunap & Pilvi Ilves & Monica H. Wojcik & Mohamed Aittaleb & Klaus Brusgaard & Fadel Tissir & Guido Rubboli
- 1-18 Single-cell multiplex approaches deeply map ON-target CRISPR-genotoxicity and reveal its mitigation by palbociclib and long-term engraftment
by Julian Boutin & Sabrina Fayet & Victor Marin & Camille Bergès & Maude Riandière & Jérôme Toutain & Isabelle Lamrissi-Garcia & Chloé Thibault & David Cappellen & Sandrine Dabernat & Arthur Poulet & Maëla Francillette & Nathalie Droin & Christelle Debeissat & Philippe Brunet de la Grange & François Moreau-Gaudry & Aurélie Bedel
- 1-18 The genetic and biochemical basis of human leading strand synthesis
by Alessandro Agnarelli & Lauryn Buckley-Benbow & Meryem Ozgencil & Melanie Lad & Khamal Kwesi Ampah & Alex Kalinka & Ondrej Belan & Sarah Maslen & Mark J. Skehel & David Walter & Matthew Day & Roberto Bellelli
- 1-18 Actin dysregulation induces neuroendocrine plasticity and immune evasion: a vulnerability of small cell lung cancer
by Yoojeong Seo & Shengzhe Zhang & Jinho Jang & Kyung-Pil Ko & Kee-Beom Kim & Yuanjian Huang & Dong-Wook Kim & Bongjun Kim & Gengyi Zou & Jie Zhang & Sohee Jun & Wonhong Chu & Nicole A. Kirk & Ye Eun Hwang & Young Ho Ban & Shilpa S. Dhar & Joseph M. Chan & Min Gyu Lee & Charles M. Rudin & Kwon-Sik Park & Jae-Il Park
- 1-18 Flexible robotic hand harnesses large deformations for full-coverage human-like multimodal haptic perception
by Yanzhe Wang & Haotian Guo & Hao Wu & Huixu Dong
- 1-18 Feedback-induced attitudinal changes in risk preferences
by Antonios Nasioulas & Elise Potier & Fabien Cerrotti & Maël Lebreton & Stefano Palminteri
- 1-18 IL-17A is increased in diabetic wounds and impairs keratinocyte function via histone demethylase JMJD3
by Jadie Y. Moon & Sonya J. Wolf & Amrita D. Joshi & He Zhang & James Shadiow & Tyler M. Bauer & Kevin D. Mangum & Lindsey D. Hughes & Christopher O. Audu & William J. Melvin & Emily C. Barrett & Sabrina Rocco & Gabriela Saldana de Jimenez & Amber L. Estor & Moses Nelapudi & Qinmengge Li & Rachael Bogle & Benjamin Levi & Frank M. Davis & Andrea T. Obi & Bethany B. Moore & Lam C. Tsoi & Johann E. Gudjonsson & Katherine A. Gallagher
- 1-18 Tracing the origin of myofibroblasts in kidney fibrosis
by Shun He & Tianchang Xia & Zhihou Guo & Xin Song & Haichang Wang & Haojie He & Ke Jia & Raodan Chen & Bin Zhou & Lingjuan He
- 1-18 A high-throughput, flow cytometry approach to measure phase behavior and exchange in biomolecular condensates
by Yuchen He & George M. Ongwae & Anupam Mondal & Joel A. Moses & Jeetain Mittal & Marcos M. Pires
- 1-18 Molecular mechanisms of receptor recognition and antibody neutralization of coxsackievirus A6
by Xianliang Ke & Xue Li & Zeyu Liu & Kexin Liu & Weichi Liu & Xingyu Yan & Bo Shu & Chao Zhang
- 1-18 Rehydration rescues Il22−/− mice from lethal Citrobacter rodentium infection
by Vishwas Mishra & Zuza Kozik & Priyanka Biswas & Jyoti Choudhary & Joshua L. C. Wong & Gad Frankel
- 1-18 SigmaR1 is an auxiliary translocon factor with lipid-binding activity that regulates protein and lipid droplet homeostasis
by Xuewen Hu & Tiantian Zhou & Tiansi Cui & Yuanjiao Du & Chunyu Song & Weiping Chang & Juan Xiong & Jichao Qin & Lin Deng & Wei-Ke Ji
- 1-18 Critical scaling of novelty in the cortex
by Tiago L. Ribeiro & Ali Vakili & Bridgette Gifford & Raiyyan Siddiqui & Vincent Sinfuego & Sinisa Pajevic & Dietmar Plenz
- 1-18 A metabolism-chromatin axis promotes differential ribosomal RNA transcription in the human malaria parasite
by Justine E. Couble & Tiziano Vignolini & Grégory Doré & Selina Mussgnug & Bérangère Lombard & Michael Richard & Damarys Loew & Michael Büttner & Rafael Dueñas-Sánchez & Gernot Poschet & Jessica M. Bryant & Sebastian Baumgarten
- 1-18 K48-ubiquitin-dependent proteases cut-up post-ER proteins
by Annabel Y. Minard & Stanley Winistorfer & Liping Yu & Robert C. Piper
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