IDEAS home Printed from
   My bibliography  Save this paper

Using health state utility values from the general population to approximate baselines in decision analytic models when condition specific data are not available


  • Ara, R
  • Brazier, JE


Decision analytic models in healthcare require baseline health related quality of life (HRQoL) data to accurately assess the benefits of interventions. The use of inappropriate baselines such as assuming the value of perfect health (EQ-5D = 1) for not having a condition may overestimate the benefits of some treatment and thus distort policy decisions informed by cost per QALY thresholds. The primary objective was to determine if data from the general population are appropriate for baseline health state utility values (HSUVs) when condition-specific data are not available. Methods: Data from four consecutive Health Surveys for England were pooled. Self-reported health status and EQ-5D data were extracted and used to generate mean HSUVs for cohorts with or without prevalent health conditions. These were compared with mean HSUVs from all respondents irrespective of health status. Results: Over 45% of respondents (n=41,174) reported at least one health condition and almost 20% reported at least two. Our results suggest that data from the general population could be used to approximate baseline HSUVs in some analyses but not all. In particular, HSUVs from the general population would not be an appropriate baseline for cohorts who have just one health condition. In these instances, if condition-specific data are not available, data from respondents who report they do not have a prevalent health condition may be more appropriate. Exploratory analyses suggest the decrement on HRQoL may not be constant across ages for all conditions and these relationships may be condition-specific. Additional research is required to validate our findings.

Suggested Citation

  • Ara, R & Brazier, JE, 2010. "Using health state utility values from the general population to approximate baselines in decision analytic models when condition specific data are not available," MPRA Paper 29946, University Library of Munich, Germany.
  • Handle: RePEc:pra:mprapa:29946

    Download full text from publisher

    File URL:
    File Function: original version
    Download Restriction: no

    More about this item


    health state utility values; baseline; quality of life; EQ-5D; age-adjusted;

    JEL classification:

    • I31 - Health, Education, and Welfare - - Welfare, Well-Being, and Poverty - - - General Welfare, Well-Being
    • I19 - Health, Education, and Welfare - - Health - - - Other


    Access and download statistics


    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:pra:mprapa:29946. See general information about how to correct material in RePEc.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: (Joachim Winter). General contact details of provider: .

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service hosted by the Research Division of the Federal Reserve Bank of St. Louis . RePEc uses bibliographic data supplied by the respective publishers.