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Bayesian Inference for Skew-normal Linear Mixed Models

Author

Listed:
  • R.B. Arellano-Valle
  • H. Bolfarine
  • V.H. Lachos

Abstract

Linear mixed models (LMM) are frequently used to analyze repeated measures data, because they are more flexible to modelling the correlation within-subject, often present in this type of data. The most popular LMM for continuous responses assumes that both the random effects and the within-subjects errors are normally distributed, which can be an unrealistic assumption, obscuring important features of the variations present within and among the units (or groups). This work presents skew-normal liner mixed models (SNLMM) that relax the normality assumption by using a multivariate skew-normal distribution, which includes the normal ones as a special case and provides robust estimation in mixed models. The MCMC scheme is derived and the results of a simulation study are provided demonstrating that standard information criteria may be used to detect departures from normality. The procedures are illustrated using a real data set from a cholesterol study.

Suggested Citation

  • R.B. Arellano-Valle & H. Bolfarine & V.H. Lachos, 2007. "Bayesian Inference for Skew-normal Linear Mixed Models," Journal of Applied Statistics, Taylor & Francis Journals, vol. 34(6), pages 663-682.
    • Handle: RePEc:taf:japsta:v:34:y:2007:i:6:p:663-682
    DOI: 10.1080/02664760701236905
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