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International Valuation Protocol for the EQ-5D-Y-3L


  • Juan M. Ramos-Goñi

    (Axentiva Solutions
    EuroQol Research Foundation)

  • Mark Oppe

    (Axentiva Solutions
    EuroQol Research Foundation)

  • Elly Stolk

    (EuroQol Research Foundation)

  • Koonal Shah

    (Office of Health Economics

  • Simone Kreimeier

    (Bielefeld University)

  • Oliver Rivero-Arias

    (University of Oxford)

  • Nancy Devlin

    (Office of Health Economics
    University of Melbourne)


The EQ-5D-Y-3L is a generic, health-related, quality-of-life instrument for use in younger populations. Some methodological studies have explored the valuation of children’s EQ-5D-Y-3L health states. There are currently no published value sets available for the EQ-5D-Y-3L that are appropriate for use in a cost-utility analysis. The aim of this article was to describe the development of the valuation protocol for the EQ-5D-Y-3L instrument. There were several research questions that needed to be answered to develop a valuation protocol for EQ-5D-Y-3L health states. Most important of these were: (1) Do we need to obtain separate values for the EQ-5D-Y-3L, or can we use the ones from the EQ-5D-3L? (2) Whose values should we elicit: children or adults? (3) Which valuation methods should be used to obtain values for child’s health states that are anchored in Full health = 1 and Dead = 0? The EuroQol Research Foundation has pursued a research programme to provide insight into these questions. In this article, we summarized the results of the research programme concluding with the description of the features of the EQ-5D-Y-3L valuation protocol. The tasks included in the protocol for valuing EQ-5D-Y-3L health states are discrete choice experiments for obtaining the relative importance of dimensions/levels and composite time-trade-off for anchoring the discrete choice experiment values on 1 = Full Health and 0 = Dead. This protocol is now available for use by research teams to generate EQ-5D-Y-3L value sets for their countries allowing the implementation of a cost-utility analysis for younger populations.

Suggested Citation

  • Juan M. Ramos-Goñi & Mark Oppe & Elly Stolk & Koonal Shah & Simone Kreimeier & Oliver Rivero-Arias & Nancy Devlin, 2020. "International Valuation Protocol for the EQ-5D-Y-3L," PharmacoEconomics, Springer, vol. 38(7), pages 653-663, July.
  • Handle: RePEc:spr:pharme:v:38:y:2020:i:7:d:10.1007_s40273-020-00909-3
    DOI: 10.1007/s40273-020-00909-3

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    References listed on IDEAS

    1. Benjamin M. Craig & Wolfgang Greiner & Derek S. Brown & Bryce B. Reeve, 2016. "Valuation of Child Health‐Related Quality of Life in the United States," Health Economics, John Wiley & Sons, Ltd., vol. 25(6), pages 768-777, June.
    2. Jeff Richardson & Neil Atherton Day & Stuart Peacock & Angelo Iezzi, 2004. "Measurement of the Quality of Life for Economic Evaluation and the Assessment of Quality of Life (AQoL) Mark 2 Instrument," Australian Economic Review, The University of Melbourne, Melbourne Institute of Applied Economic and Social Research, vol. 37(1), pages 62-88, March.
    3. Shah, K.K & Ramos-Goñi, J.M & Kreimeier, S. & Devlin, N.J, 2020. "Anchoring Latent Scale Values for the EQ-5D-Y at 0 = Dead," Research Papers 002235, Office of Health Economics.
    4. Angela Robinson & David Parkin, 2002. "Recognising diversity in public preferences: the use of preference sub‐groups in cost‐effectiveness analysis. A response to Sculpher and Gafni," Health Economics, John Wiley & Sons, Ltd., vol. 11(7), pages 649-651, October.
    5. David J. Mott & Koonal K. Shah & Juan Manuel Ramos-Goñi & Nancy J. Devlin & Oliver Rivero-Arias, 2021. "Valuing EQ-5D-Y-3L Health States Using a Discrete Choice Experiment: Do Adult and Adolescent Preferences Differ?," Medical Decision Making, , vol. 41(5), pages 584-596, July.
    6. Katherine Stevens, 2011. "Assessing the performance of a new generic measure of health-related quality of life for children and refining it for use in health state valuation," Applied Health Economics and Health Policy, Springer, vol. 9(3), pages 157-169, May.
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    Blog mentions

    As found by, the blog aggregator for Economics research:
    1. Chris Sampson’s journal round-up for 29th June 2020
      by Chris Sampson in The Academic Health Economists' Blog on 2020-06-29 11:00:06


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    Cited by:

    1. Stefan A. Lipman & Liying Zhang & Koonal K. Shah & Arthur E. Attema, 2023. "Time and lexicographic preferences in the valuation of EQ-5D-Y with time trade-off methodology," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 24(2), pages 293-305, March.
    2. S. A. Lipman & V. T. Reckers-Droog & M. Karimi & M. Jakubczyk & A. E. Attema, 2021. "Self vs. other, child vs. adult. An experimental comparison of valuation perspectives for valuation of EQ-5D-Y-3L health states," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 22(9), pages 1507-1518, December.

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