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Vector analysis of corneal astigmatism in cataractous eyes based on IOLMaster 700 biometry

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  • Achim Langenbucher
  • Jascha Wendelstein
  • Alan Cayless
  • Peter Hoffmann
  • Nóra Szentmáry

Abstract

Purpose: The purpose of this study was to investigate the effect of the corneal back surface by comparing the keratometric astigmatism (K, derived from the corneal front surface) of a modern optical biometer against astigmatism of Total Keratometry (TK, derived from both corneal surfaces) in a large population with cataractous eyes. The results were then used to define linear prediction models to map K to TK. Methods: From a large dataset containing bilateral biometric measurements (IOLMaster 700) in 9736 patients prior to cataract surgery, the total corneal astigmatism was decomposed into vectors for K, corneal back surface (BS), and TK. A multivariate prediction model (MV), simplified model with separation of vector components (SM) and a constant model (CM) were defined to map K to TK vector components. Results: The K centroid (X/Y) showed some astigmatism with-the-rule (0.1981/-0.0211 dioptre (dpt)) whereas the TK centroid was located around zero (-0.0071/-0.0381 dpt against-the-rule) and the BS centroid showed systematic astigmatism against-the-rule (-0.2367/-0.0145 dpt). The respective TK–K centroid was located at -0.2052/-0.0302 dpt. The MV model showed the same performance (i.e. mean absolute residuum) as the SM did (0.1098 and 0.1099 dpt respectively) while the CM performed only slightly worse (0.1121 dpt mean absolute residuum). Conclusion: In cases where tomographic data are unavailable statistical models could be used to consider the overall contribution of the back surface to the total corneal astigmatism. Since the performance of the CM is sufficiently close to that of MV and SM we recommend using the CM which can be directly considered e.g. as surgically induced astigmatism.

Suggested Citation

  • Achim Langenbucher & Jascha Wendelstein & Alan Cayless & Peter Hoffmann & Nóra Szentmáry, 2024. "Vector analysis of corneal astigmatism in cataractous eyes based on IOLMaster 700 biometry," PLOS ONE, Public Library of Science, vol. 19(4), pages 1-14, April.
    • Handle: RePEc:plo:pone00:0300576
    DOI: 10.1371/journal.pone.0300576
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    References listed on IDEAS

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    1. Achim Langenbucher & Nóra Szentmáry & Alan Cayless & Jascha Wendelstein & Peter Hoffmann, 2023. "Prediction of corneal power vectors after cataract surgery with toric lens implantation–A vector analysis," PLOS ONE, Public Library of Science, vol. 18(9), pages 1-18, September.
    2. Henze, Norbert & Wagner, Thorsten, 1997. "A New Approach to the BHEP Tests for Multivariate Normality," Journal of Multivariate Analysis, Elsevier, vol. 62(1), pages 1-23, July.
    3. Achim Langenbucher & Nóra Szentmáry & Alan Cayless & Veronika Röggla & Christina Leydolt & Jascha Wendelstein & Peter Hoffmann, 2022. "Similarity of eyes in a cataractous population—How reliable is the biometry of the fellow eye for lens power calculation?," PLOS ONE, Public Library of Science, vol. 17(6), pages 1-14, June.
    4. Baringhaus, Ludwig & Gaigall, Daniel, 2017. "Hotelling’s T2 tests in paired and independent survey samples: An efficiency comparison," Journal of Multivariate Analysis, Elsevier, vol. 154(C), pages 177-198.
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