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Tuberculosis control at a South African correctional centre: Diagnosis, treatment and strain characterisation

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  • Kathleen Baird
  • Halima Said
  • Hendrik J Koornhof
  • Adriano Gianmaria Duse

Abstract

Background: Correctional centres provide ideal conditions for tuberculosis (TB) transmission and disease progression. Despite the high TB incidence and incarceration rate in South Africa, data from South African correctional centres are scarce. Thus, the study evaluated TB diagnosis, treatment initiation and completion, and identified prevalent Mycobacterium tuberculosis strains among detainees entering a South African correctional centre. Methods: This study was a prospective observational study that enrolled participants between February and September 2017 from a correctional centre located in the Western Cape, South Africa. All adult male detainees who tested positive for TB during admission screening were eligible to participate in the study. Sputum samples from enrolled participants underwent smear microscopy and culture. Strain typing was performed on culture-positive samples. The time between specimen collection and diagnosis, the time between diagnosis and treatment initiation, and the proportion of detainees completing TB treatment at the correctional centre were calculated. Results: During the study period, 130 TB cases were detected through routine admission screening (126 male, 2 female, 2 juvenile). Out of the 126 eligible male detainees, 102 were enrolled in the study (81%, 102/126). All TB cases were detected within 30 hrs of admission screening. The majority (78%, 80/102) of participants started treatment within 48 hrs of TB diagnosis. However, only 8% (9/102) of participants completed treatment at the correction centre. Sputa from 90 of the 102 participants were available for smear and culture. There was a high smear positivity, with 49% (44/90) of isolates being smear positive. The Beijing family was the most frequent lineage (55.2%) in the study. Conclusion: The strengths of the current TB control efforts at the correctional centre include rapid detection of cases through admission screening and prompt treatment initiation. However, a high number of detainees exiting before treatment completion highlights the need to strengthen links between correctional TB services and community TB services to ensure detainees complete TB treatment after release and prevent TB transmission.

Suggested Citation

  • Kathleen Baird & Halima Said & Hendrik J Koornhof & Adriano Gianmaria Duse, 2022. "Tuberculosis control at a South African correctional centre: Diagnosis, treatment and strain characterisation," PLOS ONE, Public Library of Science, vol. 17(11), pages 1-14, November.
    • Handle: RePEc:plo:pone00:0277459
    DOI: 10.1371/journal.pone.0277459
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    1. Imad Cherkaoui & Radia Sabouni & Iraqi Ghali & Darya Kizub & Alexander C Billioux & Kenza Bennani & Jamal Eddine Bourkadi & Abderrahmane Benmamoun & Ouafae Lahlou & Rajae El Aouad & Kelly E Dooley, 2014. "Treatment Default amongst Patients with Tuberculosis in Urban Morocco: Predicting and Explaining Default and Post-Default Sputum Smear and Drug Susceptibility Results," PLOS ONE, Public Library of Science, vol. 9(4), pages 1-9, April.
    2. Hargreaves, J.R. & Boccia, D. & Evans, C.A. & Adato, M. & Petticrew, M. & Porter, J.D., 2011. "The social determinants of tuberculosis: from evidence to action," American Journal of Public Health, American Public Health Association, vol. 101(4), pages 654-662.
    3. Lönnroth, Knut & Jaramillo, Ernesto & Williams, Brian G. & Dye, Christopher & Raviglione, Mario, 2009. "Drivers of tuberculosis epidemics: The role of risk factors and social determinants," Social Science & Medicine, Elsevier, vol. 68(12), pages 2240-2246, June.
    4. repec:plo:pmed00:1000381 is not listed on IDEAS
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