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The health effects associated with physical, sexual and psychological gender-based violence against men and women: a Burden of Proof study

Author

Listed:
  • Caroline Stein

    (University of Washington
    University of Washington)

  • Luisa S. Flor

    (University of Washington
    University of Washington)

  • Gabriela F. Gil

    (University of Washington)

  • Mariam Khalil

    (University of Washington)

  • Molly Herbert

    (University of Washington)

  • Aleksandr Y. Aravkin

    (University of Washington
    University of Washington)

  • Alejandra Arrieta

    (University of Washington
    University of Washington)

  • María Jose Baeza de Robba

    (Pontifical Catholic University of Chile
    University of Michigan)

  • Flavia Bustreo

    (Fondation Botnar
    Partnership for Maternal, Newborn and Child Health)

  • Jack Cagney

    (University of Washington)

  • Renzo J. C. Calderon-Anyosa

    (McGill University)

  • Sinclair Carr

    (University of Washington)

  • Jaidev Kaur Chandan

    (University of Warwick
    University of Birmingham)

  • Joht Singh Chandan

    (University of Birmingham)

  • Carolina V. N. Coll

    (Federal University of Pelotas
    Federal University of Pelotas)

  • Fabiana Martins Dias Andrade

    (Federal University of Minas Gerais)

  • Gisele N. Andrade

    (Federal University of Minas Gerais)

  • Alexandra N. Debure

    (University of Miami)

  • Erin DeGraw

    (University of Washington)

  • Ben Hammond

    (University of Birmingham)

  • Simon I. Hay

    (University of Washington
    University of Washington)

  • Felicia M. Knaul

    (University of Miami
    David Geffen School of Medicine, UCLA
    Tecnológico de Monterrey Faculty of Excellence
    A.C.)

  • Rachel Q. H. Lim

    (University of Birmingham)

  • Susan A. McLaughlin

    (University of Washington)

  • Nicholas Metheny

    (Emory University)

  • Sonica Minhas

    (University of Birmingham)

  • Jasleen K. Mohr

    (University of Birmingham)

  • Erin C. Mullany

    (University of Washington)

  • Christopher J. L. Murray

    (University of Washington
    University of Washington)

  • Erin M. O’Connell

    (University of Washington)

  • Vedavati Patwardhan

    (UC San Diego School of Medicine)

  • Sofia Reinach

    (Vital Strategies)

  • Dalton Scott

    (University of Miami)

  • Cory N. Spencer

    (University of Washington)

  • Reed J. D. Sorensen

    (University of Washington)

  • Heidi Stöckl

    (Ludwig-Maximilians-University Munich)

  • Aisha Twalibu

    (University of Washington
    University of Washington)

  • Aiganym Valikhanova

    (University of Washington)

  • Nádia Vasconcelos

    (University of Washington
    Federal University of Minas Gerais)

  • Peng Zheng

    (University of Washington
    University of Washington)

  • Emmanuela Gakidou

    (University of Washington
    University of Washington)

Abstract

The health impacts of exposure to physical, sexual or psychological gender-based violence (GBV) against men and women are substantial yet not well delineated. We systematically reviewed and meta-analysed 40 studies to evaluate the associations between GBV (including but not limited to intimate partner violence) and eight health outcomes: sexually transmitted infections excluding HIV, maternal abortion and miscarriage, HIV/AIDS, major depressive disorder, anxiety disorders, drug use disorders, alcohol use disorders and self-harm. Using the Burden of Proof methods, we generated conservative metrics of association—including star ratings from one to five—reflecting both effect size and evidence strength. Sexual violence was associated with six outcomes, with moderate, three-star evidence of association for sexually transmitted infections, maternal abortion and miscarriage, and major depressive disorder—increasing the risk by at least 104%, 101% and 50%, respectively. Seven outcomes were associated with physical GBV with two- or one-star associations, reflecting weak associations and/or inconsistent evidence. Of the four health outcomes analysed in relation to psychological GBV, one, major depressive disorder, had a significant association with a one-star rating. These findings emphasize the serious health consequences of GBV for survivors and the necessity of additional data to further our understanding of this complex public health issue.

Suggested Citation

  • Caroline Stein & Luisa S. Flor & Gabriela F. Gil & Mariam Khalil & Molly Herbert & Aleksandr Y. Aravkin & Alejandra Arrieta & María Jose Baeza de Robba & Flavia Bustreo & Jack Cagney & Renzo J. C. Cal, 2025. "The health effects associated with physical, sexual and psychological gender-based violence against men and women: a Burden of Proof study," Nature Human Behaviour, Nature, vol. 9(6), pages 1201-1216, June.
  • Handle: RePEc:nat:nathum:v:9:y:2025:i:6:d:10.1038_s41562-025-02144-2
    DOI: 10.1038/s41562-025-02144-2
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    References listed on IDEAS

    as
    1. Luisa S. Flor & Caroline Stein & Gabriela F. Gil & Mariam Khalil & Molly Herbert & Aleksandr Y. Aravkin & Alejandra Arrieta & María Jose Baeza de Robba & Flavia Bustreo & Jack Cagney & Renzo J. C. Cal, 2025. "Health effects associated with exposure of children to physical violence, psychological violence and neglect: a Burden of Proof study," Nature Human Behaviour, Nature, vol. 9(6), pages 1217-1236, June.
    2. Gretchen A Stevens & Leontine Alkema & Robert E Black & J Ties Boerma & Gary S Collins & Majid Ezzati & John T Grove & Daniel R Hogan & Margaret C Hogan & Richard Horton & Joy E Lawn & Ana Marušić & C, 2016. "Guidelines for Accurate and Transparent Health Estimates Reporting: the GATHER statement," PLOS Medicine, Public Library of Science, vol. 13(6), pages 1-8, June.
    3. Whitaker, D.J. & Haileyesus, T. & Swahn, M. & Saltzman, L.S., 2007. "Differences in frequency of violence and reported injury between relationships with reciprocal and nonreciprocal intimate partner violence," American Journal of Public Health, American Public Health Association, vol. 97(5), pages 941-947.
    4. Matthew J Page & Joanne E McKenzie & Patrick M Bossuyt & Isabelle Boutron & Tammy C Hoffmann & Cynthia D Mulrow & Larissa Shamseer & Jennifer M Tetzlaff & Elie A Akl & Sue E Brennan & Roger Chou & Jul, 2021. "The PRISMA 2020 statement: An updated guideline for reporting systematic reviews," PLOS Medicine, Public Library of Science, vol. 18(3), pages 1-15, March.
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