Genetically-encoded targeted protein degradation technology to remove endogenous condensation-prone proteins and improve crop performance
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DOI: 10.1038/s41467-025-56570-x
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- Jae-Hoon Jung & Antonio D. Barbosa & Stephanie Hutin & Janet R. Kumita & Mingjun Gao & Dorothee Derwort & Catarina S. Silva & Xuelei Lai & Elodie Pierre & Feng Geng & Sol-Bi Kim & Sujeong Baek & Chloe, 2020. "A prion-like domain in ELF3 functions as a thermosensor in Arabidopsis," Nature, Nature, vol. 585(7824), pages 256-260, September.
- Frederik Faden & Thomas Ramezani & Stefan Mielke & Isabel Almudi & Knud Nairz & Marceli S. Froehlich & Jörg Höckendorff & Wolfgang Brandt & Wolfgang Hoehenwarter & R. Jürgen Dohmen & Arp Schnittger & , 2016. "Phenotypes on demand via switchable target protein degradation in multicellular organisms," Nature Communications, Nature, vol. 7(1), pages 1-15, November.
- Xiaofeng Fang & Liang Wang & Ryo Ishikawa & Yaoxi Li & Marc Fiedler & Fuquan Liu & Grant Calder & Beth Rowan & Detlef Weigel & Pilong Li & Caroline Dean, 2019. "Arabidopsis FLL2 promotes liquid–liquid phase separation of polyadenylation complexes," Nature, Nature, vol. 569(7755), pages 265-269, May.
- Dmitri A. Nusinow & Anne Helfer & Elizabeth E. Hamilton & Jasmine J. King & Takato Imaizumi & Thomas F. Schultz & Eva M. Farré & Steve A. Kay, 2011. "The ELF4–ELF3–LUX complex links the circadian clock to diurnal control of hypocotyl growth," Nature, Nature, vol. 475(7356), pages 398-402, July.
- Zhaoyang Li & Cen Wang & Ziying Wang & Chenggang Zhu & Jie Li & Tian Sha & Lixiang Ma & Chao Gao & Yi Yang & Yimin Sun & Jian Wang & Xiaoli Sun & Chenqi Lu & Marian Difiglia & Yanai Mei & Chen Ding & , 2019. "Allele-selective lowering of mutant HTT protein by HTT–LC3 linker compounds," Nature, Nature, vol. 575(7781), pages 203-209, November.
- Jong Hum Kim & Christian Danve M. Castroverde & Shuai Huang & Chao Li & Richard Hilleary & Adam Seroka & Reza Sohrabi & Diana Medina-Yerena & Bethany Huot & Jie Wang & Kinya Nomura & Sharon K. Marr & , 2022. "Increasing the resilience of plant immunity to a warming climate," Nature, Nature, vol. 607(7918), pages 339-344, July.
- Guoyong Xu & George H. Greene & Heejin Yoo & Lijing Liu & Jorge Marqués & Jonathan Motley & Xinnian Dong, 2017. "Global translational reprogramming is a fundamental layer of immune regulation in plants," Nature, Nature, vol. 545(7655), pages 487-490, May.
- Siyi Guo & Yunyuan Xu & Huanhuan Liu & Zhiwei Mao & Cui Zhang & Yan Ma & Qirui Zhang & Zheng Meng & Kang Chong, 2013. "The interaction between OsMADS57 and OsTB1 modulates rice tillering via DWARF14," Nature Communications, Nature, vol. 4(1), pages 1-12, June.
- Yanfei Ma & Andrej Miotk & Zoran Šutiković & Olga Ermakova & Christian Wenzl & Anna Medzihradszky & Christophe Gaillochet & Joachim Forner & Gözde Utan & Klaus Brackmann & Carlos S. Galván-Ampudia & T, 2019. "WUSCHEL acts as an auxin response rheostat to maintain apical stem cells in Arabidopsis," Nature Communications, Nature, vol. 10(1), pages 1-11, December.
- Jun Lyu & Liyu Huang & Shilai Zhang & Yesheng Zhang & Weiming He & Peng Zeng & Yan Zeng & Guangfu Huang & Jing Zhang & Min Ning & Yachong Bao & Shilei Zhao & Qi Fu & Len J. Wade & Hua Chen & Wen Wang , 2020. "Neo-functionalization of a Teosinte branched 1 homologue mediates adaptations of upland rice," Nature Communications, Nature, vol. 11(1), pages 1-13, December.
- Julia Bailey-Serres & Jane E. Parker & Elizabeth A. Ainsworth & Giles E. D. Oldroyd & Julian I. Schroeder, 2019. "Genetic strategies for improving crop yields," Nature, Nature, vol. 575(7781), pages 109-118, November.
- Shuai Huang & Shiwei Zhu & Pradeep Kumar & John D. MacMicking, 2021. "A phase-separated nuclear GBPL circuit controls immunity in plants," Nature, Nature, vol. 594(7863), pages 424-429, June.
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