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A precision environmental health approach to prevention of human disease

Author

Listed:
  • Andrea Baccarelli

    (Columbia University Mailman School of Public Health)

  • Dana C. Dolinoy

    (University of Michigan School of Public Health)

  • Cheryl Lyn Walker

    (Baylor College of Medicine)

Abstract

Human health is determined by the interaction of our environment with the genome, epigenome, and microbiome, which shape the transcriptomic, proteomic, and metabolomic landscape of cells and tissues. Precision environmental health is an emerging field leveraging environmental and system-level (‘omic) data to understand underlying environmental causes of disease, identify biomarkers of exposure and response, and develop new prevention and intervention strategies. In this article we provide real-life illustrations of the utility of precision environmental health approaches, identify current challenges in the field, and outline new opportunities to promote health through a precision environmental health framework.

Suggested Citation

  • Andrea Baccarelli & Dana C. Dolinoy & Cheryl Lyn Walker, 2023. "A precision environmental health approach to prevention of human disease," Nature Communications, Nature, vol. 14(1), pages 1-11, December.
    • Handle: RePEc:nat:natcom:v:14:y:2023:i:1:d:10.1038_s41467-023-37626-2
    DOI: 10.1038/s41467-023-37626-2
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    References listed on IDEAS

    as
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    Cited by:

    1. Nikos Stratakis & Augusto Anguita-Ruiz & Lorenzo Fabbri & Léa Maitre & Juan R. González & Sandra Andrusaityte & Xavier Basagaña & Eva Borràs & Hector C. Keun & Lida Chatzi & David V. Conti & Jesse Goo, 2025. "Multi-omics architecture of childhood obesity and metabolic dysfunction uncovers biological pathways and prenatal determinants," Nature Communications, Nature, vol. 16(1), pages 1-15, December.

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