IDEAS home Printed from
   My bibliography  Save this article

Bayesian sample size determination for binary regression with a misclassified covariate and no gold standard


  • Beavers, Daniel P.
  • Stamey, James D.


Covariate misclassification is a common problem in epidemiology, genetics, and other biomedical areas. Because this form of misclassification is known to bias estimators, accounting for it at the design stage is of high importance. In this paper, we extend on previous work applied to response misclassification by developing a Bayesian approach to sample size determination for a covariate misclassification model with no gold standard. Our procedure considers both conditionally independent tests and tests in which dependence exists between classifiers. We specifically consider a Bayesian power criterion for the sample size determination scheme, and we demonstrate the improvement in model power for our dual classifier approach compared to a naïve single classifier approach.

Suggested Citation

  • Beavers, Daniel P. & Stamey, James D., 2012. "Bayesian sample size determination for binary regression with a misclassified covariate and no gold standard," Computational Statistics & Data Analysis, Elsevier, vol. 56(8), pages 2574-2582.
  • Handle: RePEc:eee:csdana:v:56:y:2012:i:8:p:2574-2582
    DOI: 10.1016/j.csda.2012.02.014

    Download full text from publisher

    File URL:
    Download Restriction: Full text for ScienceDirect subscribers only.

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    1. van Wieringen, Wessel N., 2005. "On identifiability of certain latent class models," Statistics & Probability Letters, Elsevier, vol. 75(3), pages 211-218, December.
    2. Nandini Dendukuri & Elham Rahme & Patrick Bélisle & Lawrence Joseph, 2004. "Bayesian Sample Size Determination for Prevalence and Diagnostic Test Studies in the Absence of a Gold Standard Test," Biometrics, The International Biometric Society, vol. 60(2), pages 388-397, June.
    3. Hironori Fujisawa & Shizue Izumi, 2000. "Inference about Misclassification Probabilities from Repeated Binary Responses," Biometrics, The International Biometric Society, vol. 56(3), pages 706-711, September.
    4. Dianxu Ren & Roslyn Stone, 2007. "A Bayesian Adjustment for Covariate Misclassification with Correlated Binary Outcome Data," Journal of Applied Statistics, Taylor & Francis Journals, vol. 34(9), pages 1019-1034.
    5. Satoshi Morita & Peter F. Thall & Peter Müller, 2008. "Determining the Effective Sample Size of a Parametric Prior," Biometrics, The International Biometric Society, vol. 64(2), pages 595-602, June.
    6. Nandini Dendukuri & Lawrence Joseph, 2001. "Bayesian Approaches to Modeling the Conditional Dependence Between Multiple Diagnostic Tests," Biometrics, The International Biometric Society, vol. 57(1), pages 158-167, March.
    Full references (including those not matched with items on IDEAS)


    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:csdana:v:56:y:2012:i:8:p:2574-2582. See general information about how to correct material in RePEc.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: (Dana Niculescu). General contact details of provider: .

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service hosted by the Research Division of the Federal Reserve Bank of St. Louis . RePEc uses bibliographic data supplied by the respective publishers.