IDEAS home Printed from https://ideas.repec.org/a/eee/csdana/v53y2009i12p4157-4167.html

A two-stage hierarchical regression model for meta-analysis of epidemiologic nonlinear dose-response data

Author

Listed:
  • Liu, Qin
  • Cook, Nancy R.
  • Bergström, Anna
  • Hsieh, Chung-Cheng

Abstract

To estimate a summarized dose-response relation across different exposure levels from epidemiologic data, meta-analysis often needs to take into account heterogeneity across studies beyond the variation associated with fixed effects. We extended a generalized-least-squares method and a multivariate maximum likelihood method to estimate the summarized nonlinear dose-response relation taking into account random effects. These methods are readily suited to fitting and testing models with covariates and curvilinear dose-response relations.

Suggested Citation

  • Liu, Qin & Cook, Nancy R. & Bergström, Anna & Hsieh, Chung-Cheng, 2009. "A two-stage hierarchical regression model for meta-analysis of epidemiologic nonlinear dose-response data," Computational Statistics & Data Analysis, Elsevier, vol. 53(12), pages 4157-4167, October.
    • Handle: RePEc:eee:csdana:v:53:y:2009:i:12:p:4157-4167
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S0167-9473(09)00176-5
    Download Restriction: Full text for ScienceDirect subscribers only.
    ---><---

    As the access to this document is restricted, you may want to

    for a different version of it.

    References listed on IDEAS

    as
    1. Nicola Orsini & Rino Bellocco & Sander Greenland, 2006. "Generalized least squares for trend estimation of summarized dose–response data," Stata Journal, StataCorp LLC, vol. 6(1), pages 40-57, March.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Lingqian Xu & Debapriya Mondal & David A. Polya, 2020. "Positive Association of Cardiovascular Disease (CVD) with Chronic Exposure to Drinking Water Arsenic (As) at Concentrations below the WHO Provisional Guideline Value: A Systematic Review and Meta-anal," IJERPH, MDPI, vol. 17(7), pages 1-24, April.
    2. Martin Gaksch & Rolf Jorde & Guri Grimnes & Ragnar Joakimsen & Henrik Schirmer & Tom Wilsgaard & Ellisiv B Mathiesen & Inger Njølstad & Maja-Lisa Løchen & Winfried März & Marcus E Kleber & Andreas Tom, 2017. "Vitamin D and mortality: Individual participant data meta-analysis of standardized 25-hydroxyvitamin D in 26916 individuals from a European consortium," PLOS ONE, Public Library of Science, vol. 12(2), pages 1-15, February.
    3. Crippa, Alessio & Orsini, Nicola, 2016. "Multivariate Dose-Response Meta-Analysis: The dosresmeta R Package," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 72(c01).
    4. Bo Yang & Feng-Lei Wang & Xiao-Li Ren & Duo Li, 2014. "Biospecimen Long-Chain N-3 PUFA and Risk of Colorectal Cancer: A Meta-Analysis of Data from 60,627 Individuals," PLOS ONE, Public Library of Science, vol. 9(11), pages 1-13, November.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Ali, Mumtaz & Prasad, Ramendra & Xiang, Yong & Deo, Ravinesh C., 2020. "Near real-time significant wave height forecasting with hybridized multiple linear regression algorithms," Renewable and Sustainable Energy Reviews, Elsevier, vol. 132(C).
    2. Yong-Fei Hua & Gao-Qing Wang & Wei Jiang & Jing Huang & Guo-Chong Chen & Cai-De Lu, 2016. "Vitamin C Intake and Pancreatic Cancer Risk: A Meta-Analysis of Published Case-Control and Cohort Studies," PLOS ONE, Public Library of Science, vol. 11(2), pages 1-10, February.
    3. Fatemeh Shahbazi & Marzieh Fattahi-Darghlou & Samad Moslehi & Minoo Dabiri-Golchin & Marjan Shahbazi, 2025. "Effect of music therapy on behavioral and physiological neonatal outcomes: A systematic review and dose-response meta-analysis," PLOS ONE, Public Library of Science, vol. 20(1), pages 1-15, January.
    4. Meng-Bo Hu & Sheng-Hua Liu & Hao-Wen Jiang & Pei-De Bai & Qiang Ding, 2014. "Obesity Affects the Biopsy-Mediated Detection of Prostate Cancer, Particularly High-Grade Prostate Cancer: A Dose-Response Meta-Analysis of 29,464 Patients," PLOS ONE, Public Library of Science, vol. 9(9), pages 1-10, September.
    5. Yeongkeun Kwon & Hyun Jung Kim & Sungsoo Park & Yong-Gyu Park & Kyung-Hwan Cho, 2017. "Body Mass Index-Related Mortality in Patients with Type 2 Diabetes and Heterogeneity in Obesity Paradox Studies: A Dose-Response Meta-Analysis," PLOS ONE, Public Library of Science, vol. 12(1), pages 1-14, January.
    6. Yulan Wang & Ran Cui & Yuanyuan Xiao & Juemin Fang & Qing Xu, 2015. "Effect of Carotene and Lycopene on the Risk of Prostate Cancer: A Systematic Review and Dose-Response Meta-Analysis of Observational Studies," PLOS ONE, Public Library of Science, vol. 10(9), pages 1-20, September.
    7. Rui Zhang & Jialin Fu & Justin B. Moore & Lee Stoner & Rui Li, 2021. "Processed and Unprocessed Red Meat Consumption and Risk for Type 2 Diabetes Mellitus: An Updated Meta-Analysis of Cohort Studies," IJERPH, MDPI, vol. 18(20), pages 1-15, October.
    8. GuoChao Zhong & Yi Wang & Yong Zhang & Yong Zhao, 2015. "Association between Benzodiazepine Use and Dementia: A Meta-Analysis," PLOS ONE, Public Library of Science, vol. 10(5), pages 1-16, May.
    9. Zhengtao Liu & Shuping Que & Huaijun Ning & Linlin Wang & Tao Peng, 2013. "Elevated Alanine Aminotransferase Is Strongly Associated with Incident Metabolic Syndrome: A Meta-Analysis of Prospective Studies," PLOS ONE, Public Library of Science, vol. 8(12), pages 1-11, December.
    10. Rui-Xue Huang & Yan-Ying Duan & Jian-An Hu, 2015. "Fish Intake and Risk of Liver Cancer: A Meta-Analysis," PLOS ONE, Public Library of Science, vol. 10(1), pages 1-9, January.
    11. Eujene Jung & So Yeon Kong & Young Sun Ro & Hyun Ho Ryu & Sang Do Shin, 2022. "Serum Cholesterol Levels and Risk of Cardiovascular Death: A Systematic Review and a Dose-Response Meta-Analysis of Prospective Cohort Studies," IJERPH, MDPI, vol. 19(14), pages 1-12, July.
    12. Dengfeng Gao & Ning Ning & Congxia Wang & Yuhuan Wang & Qing Li & Zhe Meng & Yang Liu & Qiang Li, 2013. "Dairy Products Consumption and Risk of Type 2 Diabetes: Systematic Review and Dose-Response Meta-Analysis," PLOS ONE, Public Library of Science, vol. 8(9), pages 1-15, September.
    13. Doris S M Chan & Rosa Lau & Dagfinn Aune & Rui Vieira & Darren C Greenwood & Ellen Kampman & Teresa Norat, 2011. "Red and Processed Meat and Colorectal Cancer Incidence: Meta-Analysis of Prospective Studies," PLOS ONE, Public Library of Science, vol. 6(6), pages 1-11, June.
    14. Junna Wang & Dandan Zhang & Rongzhong Huang & Xingsheng Li & Wenxiang Huang, 2017. "Gamma-glutamyltransferase and risk of cardiovascular mortality: A dose-response meta-analysis of prospective cohort studies," PLOS ONE, Public Library of Science, vol. 12(2), pages 1-19, February.
    15. Laura Pimpin & Jason H Y Wu & Hila Haskelberg & Liana Del Gobbo & Dariush Mozaffarian, 2016. "Is Butter Back? A Systematic Review and Meta-Analysis of Butter Consumption and Risk of Cardiovascular Disease, Diabetes, and Total Mortality," PLOS ONE, Public Library of Science, vol. 11(6), pages 1-18, June.
    16. Qianqian Liu & Min Peng & Tiantian Yang & Guomin Si, 2023. "Uric acid levels and risk of cognitive impairment: Dose-response meta-analysis of prospective cohort studies," PLOS ONE, Public Library of Science, vol. 18(11), pages 1-20, November.
    17. Dongsheng Cheng & Yang Fei & Yumei Liu & Junhui Li & Qin Xue & Xiaoxia Wang & Niansong Wang, 2014. "HbA1C Variability and the Risk of Renal Status Progression in Diabetes Mellitus: A Meta-Analysis," PLOS ONE, Public Library of Science, vol. 9(12), pages 1-13, December.
    18. Bijing Mao & Yafei Li & Zhimin Zhang & Chuan Chen & Yuanyuan Chen & Chenchen Ding & Lin Lei & Jian Li & Mei Jiang & Dong Wang & Ge Wang, 2015. "One-Carbon Metabolic Factors and Risk of Renal Cell Cancer: A Meta-Analysis," PLOS ONE, Public Library of Science, vol. 10(10), pages 1-10, October.
    19. repec:plo:pone00:0102276 is not listed on IDEAS
    20. Guochao Zhong & Yi Wang & Yong Zhang & Jeff Jianfei Guo & Yong Zhao, 2015. "Smoking Is Associated with an Increased Risk of Dementia: A Meta-Analysis of Prospective Cohort Studies with Investigation of Potential Effect Modifiers," PLOS ONE, Public Library of Science, vol. 10(3), pages 1-23, March.
    21. Lin Zhang & Xing-Huan Wang & Xin-Min Zheng & Tong-Zu Liu & Wei-Bin Zhang & Hang Zheng & Mi-Feng Chen, 2015. "Maternal Gestational Smoking, Diabetes, Alcohol Drinking, Pre-Pregnancy Obesity and the Risk of Cryptorchidism: A Systematic Review and Meta-Analysis of Observational Studies," PLOS ONE, Public Library of Science, vol. 10(3), pages 1-17, March.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:csdana:v:53:y:2009:i:12:p:4157-4167. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Catherine Liu (email available below). General contact details of provider: http://www.elsevier.com/locate/csda .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.