IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0316674.html

Effect of music therapy on behavioral and physiological neonatal outcomes: A systematic review and dose-response meta-analysis

Author

Listed:
  • Fatemeh Shahbazi
  • Marzieh Fattahi-Darghlou
  • Samad Moslehi
  • Minoo Dabiri-Golchin
  • Marjan Shahbazi

Abstract

Background: Previous studies have documented the effectiveness of music therapy in improving adverse neonatal outcomes in premature infants. However, this review aims to address the question of how long listening to music can enhance these neonatal outcomes. Methods: To conduct this dose-response meta-analysis, we searched the PubMed, Scopus, Web of Science, and Cochrane Library databases. The inclusion criteria comprised randomized clinical trials that investigated the effects of music therapy on improving adverse neonatal outcomes. Preterm infants were defined as those born between 27 and 37 weeks of gestation, as fetuses are known to respond to auditory stimuli starting at the 27th week of pregnancy. The initial search was performed on January 28, 2024, and there were no restrictions on the time frame for the search. Ultimately, we employed a two-stage random effects model using the “drmeta” package in Stata software to perform this dose-response meta-analysis. Results: In total, 30 articles (1855 participants) were identified for inclusion in our meta-analysis. According to pooled analysis with each minute increase in music therapy, the means of respiratory rate, pain score, SBP, DBP, behavioral score, and body temperature decrease by 35.3 beats per minutes, 15.3 VAS, 30.7 mmHg, 8.9 mmHg, 2.7, and 0.27°C. On the other hand, with each minute increase in listening to the music, the mean of O2 saturation, heart rate and sleep duration increase 1.7%, 89.2 beats per minutes and 5.081 minutes per day, respectively. Conclusion: Music therapy improves the neonatal outcomes of O2 saturation, heart rate, respiratory rate, sleep duration, body temperature and systolic and diastolic blood pressures. Therefore, the existence of a dose-response relationship can indicate a causal relationship between music therapy and the improvement of neonatal outcomes.

Suggested Citation

  • Fatemeh Shahbazi & Marzieh Fattahi-Darghlou & Samad Moslehi & Minoo Dabiri-Golchin & Marjan Shahbazi, 2025. "Effect of music therapy on behavioral and physiological neonatal outcomes: A systematic review and dose-response meta-analysis," PLOS ONE, Public Library of Science, vol. 20(1), pages 1-15, January.
    • Handle: RePEc:plo:pone00:0316674
    DOI: 10.1371/journal.pone.0316674
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0316674
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0316674&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0316674?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Łucja Bieleninik & Mark Ettenberger & Shulamit Epstein & Cochavit Elefant & Shmuel Arnon, 2021. "Potential Psychological and Biological Mechanisms Underlying the Effectiveness of Neonatal Music Therapy during Kangaroo Mother Care for Preterm Infants and Their Parents," IJERPH, MDPI, vol. 18(16), pages 1-12, August.
    2. Jonathan A.C. Sterne & Roger M. Harbord, 2004. "Funnel plots in meta-analysis," Stata Journal, StataCorp LLC, vol. 4(2), pages 127-141, June.
    3. Nicola Orsini & Rino Bellocco & Sander Greenland, 2006. "Generalized least squares for trend estimation of summarized dose–response data," Stata Journal, StataCorp LLC, vol. 6(1), pages 40-57, March.
    4. Loïs C. Span & Nienke H. van Dokkum & Anne-Greet Ravensbergen & Arend F. Bos & Artur C. Jaschke, 2021. "Combining Kangaroo Care and Live-Performed Music Therapy: Effects on Physiological Stability and Neurological Functioning in Extremely and Very Preterm Infants," IJERPH, MDPI, vol. 18(12), pages 1-12, June.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Ali, Mumtaz & Prasad, Ramendra & Xiang, Yong & Deo, Ravinesh C., 2020. "Near real-time significant wave height forecasting with hybridized multiple linear regression algorithms," Renewable and Sustainable Energy Reviews, Elsevier, vol. 132(C).
    2. Michael J. Crowther & Dean Langan & Alex J. Sutton, 2012. "Graphical augmentations to the funnel plot to assess the impact of a new study on an existing meta-analysis," Stata Journal, StataCorp LLC, vol. 12(4), pages 605-622, December.
    3. Solomiia Brychka & Denys Klynovskyi & Dmytro Krukovets & Artem Oharkov, 2019. "Meta-Analysis: Meta-Analysis: Effect of FX interventions on the exchange rate," Modern Economic Studies, Kyiv School of Economics, vol. 2(1), pages 24-44.
    4. Amal F. Alshammary & Khalid Khalaf Alharbi & Naif Jameel Alshehri & Vishal Vennu & Imran Ali Khan, 2021. "Metabolic Syndrome and Coronary Artery Disease Risk: A Meta-Analysis of Observational Studies," IJERPH, MDPI, vol. 18(4), pages 1-16, February.
    5. Meng-Bo Hu & Sheng-Hua Liu & Hao-Wen Jiang & Pei-De Bai & Qiang Ding, 2014. "Obesity Affects the Biopsy-Mediated Detection of Prostate Cancer, Particularly High-Grade Prostate Cancer: A Dose-Response Meta-Analysis of 29,464 Patients," PLOS ONE, Public Library of Science, vol. 9(9), pages 1-10, September.
    6. Ugur, Mehmet & Awaworyi, Sefa & Solomon, Edna, 2016. "Technological innovation and employment in derived labour demand models: A hierarchical meta-regression analysis," MPRA Paper 73557, University Library of Munich, Germany.
    7. Da-Jung Ha & Jung-Hyun Park & Su-Eun Jung & Boram Lee & Myo-Sung Kim & Kyo-Lin Sim & Yung-Hyun Choi & Chan-Young Kwon, 2021. "The Experience of Emotional Labor and Its Related Factors among Nurses in General Hospital Settings in Republic of Korea: A Systematic Review and Meta-Analysis," Sustainability, MDPI, vol. 13(21), pages 1-21, October.
    8. Christin Höge-Junge & Stefan Eckert, 2024. "Multinationality and systematic risk: a literature review and meta-analysis," Management Review Quarterly, Springer, vol. 74(1), pages 377-414, February.
    9. Nino Fonseca & Marcelino Sánchez-Rivero, 2020. "Significance bias in the tourism-led growth literature," Tourism Economics, , vol. 26(1), pages 137-154, February.
    10. Jianling Jiao & Nuonuo Chen & Ranran Yang, 2024. "How to promote green travel effectively: a study of niche information interventions based on meta-analysis," Environment, Development and Sustainability: A Multidisciplinary Approach to the Theory and Practice of Sustainable Development, Springer, vol. 26(4), pages 8267-8301, April.
    11. Yulan Wang & Ran Cui & Yuanyuan Xiao & Juemin Fang & Qing Xu, 2015. "Effect of Carotene and Lycopene on the Risk of Prostate Cancer: A Systematic Review and Dose-Response Meta-Analysis of Observational Studies," PLOS ONE, Public Library of Science, vol. 10(9), pages 1-20, September.
    12. Rui Zhang & Jialin Fu & Justin B. Moore & Lee Stoner & Rui Li, 2021. "Processed and Unprocessed Red Meat Consumption and Risk for Type 2 Diabetes Mellitus: An Updated Meta-Analysis of Cohort Studies," IJERPH, MDPI, vol. 18(20), pages 1-15, October.
    13. Ugur, Mehmet & Mitra, Arup, 2017. "Technology Adoption and Employment in Less Developed Countries: A Mixed-Method Systematic Review," World Development, Elsevier, vol. 96(C), pages 1-18.
    14. GuoChao Zhong & Yi Wang & Yong Zhang & Yong Zhao, 2015. "Association between Benzodiazepine Use and Dementia: A Meta-Analysis," PLOS ONE, Public Library of Science, vol. 10(5), pages 1-16, May.
    15. Eujene Jung & So Yeon Kong & Young Sun Ro & Hyun Ho Ryu & Sang Do Shin, 2022. "Serum Cholesterol Levels and Risk of Cardiovascular Death: A Systematic Review and a Dose-Response Meta-Analysis of Prospective Cohort Studies," IJERPH, MDPI, vol. 19(14), pages 1-12, July.
    16. Doris S M Chan & Rosa Lau & Dagfinn Aune & Rui Vieira & Darren C Greenwood & Ellen Kampman & Teresa Norat, 2011. "Red and Processed Meat and Colorectal Cancer Incidence: Meta-Analysis of Prospective Studies," PLOS ONE, Public Library of Science, vol. 6(6), pages 1-11, June.
    17. Laura Pimpin & Jason H Y Wu & Hila Haskelberg & Liana Del Gobbo & Dariush Mozaffarian, 2016. "Is Butter Back? A Systematic Review and Meta-Analysis of Butter Consumption and Risk of Cardiovascular Disease, Diabetes, and Total Mortality," PLOS ONE, Public Library of Science, vol. 11(6), pages 1-18, June.
    18. Soon, Jan-Jan & Ahmad, Siti-Aznor, 2015. "Willingly or grudgingly? A meta-analysis on the willingness-to-pay for renewable energy use," Renewable and Sustainable Energy Reviews, Elsevier, vol. 44(C), pages 877-887.
    19. Allan Mayaba Mwiinde & Patrick Kaonga & Choolwe Jacobs & Joseph Mumba Zulu & Isaac Fwemba, 2024. "Determinants of COVID-19 vaccine acceptance and hesitancy among adolescents and youths aged 10-35 years in sub-Saharan African countries: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 19(10), pages 1-21, October.
    20. Qianqian Liu & Min Peng & Tiantian Yang & Guomin Si, 2023. "Uric acid levels and risk of cognitive impairment: Dose-response meta-analysis of prospective cohort studies," PLOS ONE, Public Library of Science, vol. 18(11), pages 1-20, November.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0316674. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.