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One-Carbon Metabolic Factors and Risk of Renal Cell Cancer: A Meta-Analysis

Author

Listed:
  • Bijing Mao
  • Yafei Li
  • Zhimin Zhang
  • Chuan Chen
  • Yuanyuan Chen
  • Chenchen Ding
  • Lin Lei
  • Jian Li
  • Mei Jiang
  • Dong Wang
  • Ge Wang

Abstract

Background: Nutrients related to one-carbon metabolism were previously shown to be significantly associated with the risk of cancer. The aim of this meta-analysis was to evaluate potential relationships between one-carbon metabolic factors and renal cell cancer (RCC) risk. Methods: PubMed, EMBASE, and Cochrane Library databases were searched through March 2015 for observational studies of quantitative RCC risk estimates in relation to one-carbon metabolic factors. The relative risks (RRs) with 95% confidence intervals (CIs) measured the relationship between one-carbon metabolic factors and RCC risk using a random-effects model. Results: Of the 463 citations and abstracts identified by database search, seven cohorts from five observational studies reported data on 133,995 individuals, and included 2,441 RCC cases. Comparing the highest with the lowest category, the pooled RRs of RCC were 0.72 (95%CI: 0.52–1.00; P = 0.048) for vitamin B12. In addition, an increase in folic acid supplementation of 100 μg/day was associated with a 3% lower risk of RCC (RR, 0.97; 95%CI: 0.93–1.00; P = 0.048). Similarly, an increase of 5 nmol/L of vitamin B2 was associated with a reduced risk of RCC 0.94 (95%CI: 0.89–1.00; P = 0.045). Sensitivity analyses suggested that a higher serum vitamin B6 might contribute to a reduced risk of RCC (RR, 0.83; 95%CI: 0.77–0.89; P

Suggested Citation

  • Bijing Mao & Yafei Li & Zhimin Zhang & Chuan Chen & Yuanyuan Chen & Chenchen Ding & Lin Lei & Jian Li & Mei Jiang & Dong Wang & Ge Wang, 2015. "One-Carbon Metabolic Factors and Risk of Renal Cell Cancer: A Meta-Analysis," PLOS ONE, Public Library of Science, vol. 10(10), pages 1-10, October.
    • Handle: RePEc:plo:pone00:0141762
    DOI: 10.1371/journal.pone.0141762
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    1. Yu-Fei Zhang & Wei-Wu Shi & Hong-Fang Gao & Li Zhou & An-Ji Hou & Yu-Hao Zhou, 2014. "Folate Intake and the Risk of Breast Cancer: A Dose-Response Meta-Analysis of Prospective Studies," PLOS ONE, Public Library of Science, vol. 9(6), pages 1-11, June.
    2. Yu-Fei Zhang & Li Zhou & Hong-Wei Zhang & An-Ji Hou & Hong-Fang Gao & Yu-Hao Zhou, 2014. "Association between Folate Intake and the Risk of Lung Cancer: A Dose-Response Meta-Analysis of Prospective Studies," PLOS ONE, Public Library of Science, vol. 9(4), pages 1-9, April.
    3. Nicola Orsini & Rino Bellocco & Sander Greenland, 2006. "Generalized least squares for trend estimation of summarized dose–response data," Stata Journal, StataCorp LP, vol. 6(1), pages 40-57, March.
    4. n/a, 2015. "Book Reviews," The Energy Journal, International Association for Energy Economics, vol. 0(Number 4).
    5. A. E. Ades & G. Lu & J. P. T. Higgins, 2005. "The Interpretation of Random-Effects Meta-Analysis in Decision Models," Medical Decision Making, , vol. 25(6), pages 646-654, November.
    6. Aurelio Tobias, 1999. "Assessing the influence of a single study in the meta-anyalysis estimate," Stata Technical Bulletin, StataCorp LP, vol. 8(47).
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