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Depressive symptoms and AIDS-related mortality among a multisite cohort of HIV-positive women

Author

Listed:
  • Cook, J.A.
  • Grey, D.
  • Burke, J.
  • Cohen, M.H.
  • Gurtman, A.C.
  • Richardson, J.L.
  • Wilson, T.E.
  • Young, M.A.
  • Hessol, N.A.

Abstract

Objectives. We examined associations between depressive symptoms and AIDS-related mortality after controlling for antiretroviral therapy use, mental health treatment, medication adherence, substance abuse, clinical indicators, and demographic factors. Methods. One thousand seven hundred sixteen HIV-seropositive women completed semiannual visits from 1994 through 2001 to clinics at 6 sites. Multivariate Cox and logistic regression analyses estimated time to AIDS-related death and depressive symptom severity. Results. After we controlled for all other factors, AIDS-related deaths were more likely among women with chronic depressive symptoms, and symptoms were more severe among women in the terminal phase of their illness. Mental health service use was associated with reduced mortality. Conclusions. Treatment for depression is a critically important component of comprehensive care for HIV-seropositive women, especially those with end-stage disease.

Suggested Citation

  • Cook, J.A. & Grey, D. & Burke, J. & Cohen, M.H. & Gurtman, A.C. & Richardson, J.L. & Wilson, T.E. & Young, M.A. & Hessol, N.A., 2004. "Depressive symptoms and AIDS-related mortality among a multisite cohort of HIV-positive women," American Journal of Public Health, American Public Health Association, vol. 94(7), pages 1133-1140.
    • Handle: RePEc:aph:ajpbhl:2004:94:7:1133-1140_1
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    Citations

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    Cited by:

    1. Okeke, Edward N. & Wagner, Glenn J., 2013. "AIDS treatment and mental health: Evidence from Uganda," Social Science & Medicine, Elsevier, vol. 92(C), pages 27-34.
    2. Tsai, Alexander C. & Bangsberg, David R. & Frongillo, Edward A. & Hunt, Peter W. & Muzoora, Conrad & Martin, Jeffrey N. & Weiser, Sheri D., 2012. "Food insecurity, depression and the modifying role of social support among people living with HIV/AIDS in rural Uganda," Social Science & Medicine, Elsevier, vol. 74(12), pages 2012-2019.
    3. Dickens Akena & Seggane Musisi & John Joska & Dan J Stein, 2012. "The Association between Aids Related Stigma and Major Depressive Disorder among HIV-Positive Individuals in Uganda," PLOS ONE, Public Library of Science, vol. 7(11), pages 1-6, November.
    4. Ann N Do & Eli S Rosenberg & Patrick S Sullivan & Linda Beer & Tara W Strine & Jeffrey D Schulden & Jennifer L Fagan & Mark S Freedman & Jacek Skarbinski, 2014. "Excess Burden of Depression among HIV-Infected Persons Receiving Medical Care in the United States: Data from the Medical Monitoring Project and the Behavioral Risk Factor Surveillance System," PLOS ONE, Public Library of Science, vol. 9(3), pages 1-10, March.
    5. Feldman, Matthew B. & Weinberg, Gregg S. & Wu, Elwin, 2012. "Evaluation of a system designed to link people living with HIV/AIDS with mental health services at an AIDS-service organization," Evaluation and Program Planning, Elsevier, vol. 35(1), pages 133-138.
    6. Jason Roy & Michael J. Daniels, 2008. "A General Class of Pattern Mixture Models for Nonignorable Dropout with Many Possible Dropout Times," Biometrics, The International Biometric Society, vol. 64(2), pages 538-545, June.

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