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From lead exposure in early childhood to adolescent health: A chicago birth cohort

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  • Winter, A.S.
  • Sampson, R.J.

Abstract

Objectives. To assess the relationships between childhood lead exposure and 3 domains of later adolescent health: mental, physical, and behavioral. Methods.We followed a random sample of birth cohort members from the Project on Human Development in Chicago Neighborhoods, recruited in 1995 to 1997, to age 17 years and matched to childhood blood test results from the Department of Public Health. We used ordinary least squares regression, coarsened exact matching, and instrumental variables to assess the relationship between average blood lead levels in childhood and impulsivity, anxiety or depression, and body mass index in adolescence. All models adjusted for relevant individual, household, and neighborhood characteristics. Results. After adjustment, a 1 microgram per deciliter increase in average childhood blood lead level significantly predicts 0.06 (95% confidence interval [CI] = 0.01, 0.12) and 0.09 (95% CI = 0.03, 0.16) SD increases and a 0.37 (95% CI = 0.11, 0.64) point increase in adolescent impulsivity, anxiety or depression, and body mass index, respectively, following ordinary least squares regression. Results following matching and instrumental variable strategies are very similar. Conclusions. Childhood lead exposure undermines adolescent well-being, with implications for the persistence of racial and class inequalities, considering structural patterns of initial exposure. (Am J Public Health. 2017;107:1496-1501. doi:10.2105/ AJPH.2017.303903).

Suggested Citation

  • Winter, A.S. & Sampson, R.J., 2017. "From lead exposure in early childhood to adolescent health: A chicago birth cohort," American Journal of Public Health, American Public Health Association, vol. 107(9), pages 1496-1501.
    • Handle: RePEc:aph:ajpbhl:10.2105/ajph.2017.303903_9
    DOI: 10.2105/AJPH.2017.303903
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    Cited by:

    1. Robert J Sampson, 2019. "Neighbourhood effects and beyond: Explaining the paradoxes of inequality in the changing American metropolis," Urban Studies, Urban Studies Journal Limited, vol. 56(1), pages 3-32, January.
    2. Felner, Jennifer K. & Dudley, Terry D. & Ramirez-Valles, Jesus, 2018. "“Anywhere but here": Querying spatial stigma as a social determinant of health among youth of color accessing LGBTQ services in Chicago's Boystown," Social Science & Medicine, Elsevier, vol. 213(C), pages 181-189.
    3. Higney, Anthony & Hanley, Nick & Moro, Mirko, 2022. "The lead-crime hypothesis: A meta-analysis," Regional Science and Urban Economics, Elsevier, vol. 97(C).
    4. Deniz Yeter & Ellen C. Banks & Michael Aschner, 2020. "Disparity in Risk Factor Severity for Early Childhood Blood Lead among Predominantly African-American Black Children: The 1999 to 2010 US NHANES," IJERPH, MDPI, vol. 17(5), pages 1-26, February.
    5. Abbasi, Ali & DiTraglia, Francis J. & Gazze, Ludovica & Pals, Bridget, 2023. "Hidden hazards and screening policy: Predicting undetected lead exposure in Illinois," Journal of Health Economics, Elsevier, vol. 90(C).
    6. Jessica R. Mosher & Jim E. Banta & Rhonda Spencer-Hwang & Colleen C. Naughton & Krystin F. Kadonsky & Thomas Hile & Ryan G. Sinclair, 2024. "An Environmental Equity Assessment Using a Social Vulnerability Index during the SARS-CoV-2 Pandemic for Siting of Wastewater-Based Epidemiology Locations in the United States," Geographies, MDPI, vol. 4(1), pages 1-11, February.

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