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Maternal Hypothyroidism and Sensorineural Disability

Author

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  • Ahmed RG

    (Zoology Department, Beni-Suef University, Egypt)

Abstract

Maternal thyroid hormones (THs; 3,5,3’-triiodothyronine (T3) and thyroxin (T4)) exert vital roles throughout the development and show a permissive role in the neurological functions, in particular the sensorineural actions. The actions of THs can be mediated through the genomic and non-genomic pathways. On the other hand, there are associations between the maternal hypothyroidism and neonatal sensorineural deficits. A gestational hypothyroidism displays sensory and motor deficits, grave cognitive, permanent long-lasting variations in child brain structure, and neurodevelopmental disorders. During prenatal and early postnatal periods, any disruption in the levels of T4 or T3 can lead to irreversible disorders in sensorimotor and intelligence function, psychotic behavior, mental retardation, depression, coma and several morphological variations in the brain.

Suggested Citation

  • Ahmed RG, 2018. "Maternal Hypothyroidism and Sensorineural Disability," Global Journal of Pharmacy & Pharmaceutical Sciences, Juniper Publishers Inc., vol. 5(4), pages 92-95, April.
    • Handle: RePEc:adp:jgjpps:v:5:y:2018:i:4:p:92-95
    DOI: 10.19080/GJPPS.2018.05.555668
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    References listed on IDEAS

    as
    1. Ijae, 2002. "Reviews in Brief," Indian Journal of Agricultural Economics, Indian Society of Agricultural Economics, vol. 57(2), June.
    2. Ijae, 2002. "Reviews in Brief," Indian Journal of Agricultural Economics, Indian Society of Agricultural Economics, vol. 57(1), March.
    3. Shinji Yamaguchi & Naoya Aoki & Takaaki Kitajima & Eiji Iikubo & Sachiko Katagiri & Toshiya Matsushima & Koichi J. Homma, 2012. "Thyroid hormone determines the start of the sensitive period of imprinting and primes later learning," Nature Communications, Nature, vol. 3(1), pages 1-13, January.
    4. Ijae, 2002. "Reviews in Brief," Indian Journal of Agricultural Economics, Indian Society of Agricultural Economics, vol. 57(4), December.
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