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Generating Kidney Organoids from Human Induced Pluripotent Stem Cells- Potential for Treating Kidney Disease

Author

Listed:
  • Snehal Raut

    (Department of Foundational Medical Studies, Oakland University William Beaumont School of Medicine, USA)

Abstract

An estimated 1 million people worldwide die each year from untreated kidney disease, which is a major public health issue. Most of them require maintenance dialysis or renal transplantation. Dialysis is not a successful treatment option due to high medical expenditures and negative effects on the patients. Kidney transplantation is limited by the shortage of organ donors and the possibility of immune rejection.

Suggested Citation

  • Snehal Raut, 2023. "Generating Kidney Organoids from Human Induced Pluripotent Stem Cells- Potential for Treating Kidney Disease," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 53(5), pages 45104-45110, November.
    • Handle: RePEc:abf:journl:v:53:y:2023:i:5:p:45104-45110
    DOI: 10.26717/BJSTR.2023.53.008456
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    References listed on IDEAS

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    2. Shin-Ichi Mae & Akemi Shono & Fumihiko Shiota & Tetsuhiko Yasuno & Masatoshi Kajiwara & Nanaka Gotoda-Nishimura & Sayaka Arai & Aiko Sato-Otubo & Taro Toyoda & Kazutoshi Takahashi & Naoki Nakayama & C, 2013. "Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells," Nature Communications, Nature, vol. 4(1), pages 1-11, June.
    3. Benjamin S. Freedman & Craig R. Brooks & Albert Q. Lam & Hongxia Fu & Ryuji Morizane & Vishesh Agrawal & Abdelaziz F. Saad & Michelle K. Li & Michael R. Hughes & Ryan Vander Werff & Derek T. Peters & , 2015. "Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids," Nature Communications, Nature, vol. 6(1), pages 1-13, December.
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    JEL classification:

    • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
    • Z0 - Other Special Topics - - General

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