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Content
March 2021, Volume 591, Issue 7848
- 124-130 Global absence and targeting of protective immune states in severe COVID-19
by Alexis J. Combes & Tristan Courau & Nicholas F. Kuhn & Kenneth H. Hu & Arja Ray & William S. Chen & Nayvin W. Chew & Simon J. Cleary & Divyashree Kushnoor & Gabriella C. Reeder & Alan Shen & Jessica Tsui & Kamir J. Hiam-Galvez & Priscila Muñoz-Sandoval & Wandi S. Zhu & David S. Lee & Yang Sun & Ran You & Mélia Magnen & Lauren Rodriguez & K. W. Im & Nina K. Serwas & Aleksandra Leligdowicz & Colin R. Zamecnik & Rita P. Loudermilk & Michael R. Wilson & Chun J. Ye & Gabriela K. Fragiadakis & Mark R. Looney & Vincent Chan & Alyssa Ward & Sidney Carrillo & Michael Matthay & David J. Erle & Prescott G. Woodruff & Charles Langelier & Kirsten Kangelaris & Carolyn M. Hendrickson & Carolyn Calfee & Arjun Arkal Rao & Matthew F. Krummel - 131-136 NINJ1 mediates plasma membrane rupture during lytic cell death
by Nobuhiko Kayagaki & Opher S. Kornfeld & Bettina L. Lee & Irma B. Stowe & Karen O’Rourke & Qingling Li & Wendy Sandoval & Donghong Yan & Jing Kang & Min Xu & Juan Zhang & Wyne P. Lee & Brent S. McKenzie & Gözde Ulas & Jian Payandeh & Merone Roose-Girma & Zora Modrusan & Rohit Reja & Meredith Sagolla & Joshua D. Webster & Vicky Cho & T. Daniel Andrews & Lucy X. Morris & Lisa A. Miosge & Christopher C. Goodnow & Edward M. Bertram & Vishva M. Dixit - 137-141 Chromothripsis drives the evolution of gene amplification in cancer
by Ofer Shoshani & Simon F. Brunner & Rona Yaeger & Peter Ly & Yael Nechemia-Arbely & Dong Hyun Kim & Rongxin Fang & Guillaume A. Castillon & Miao Yu & Julia S. Z. Li & Ying Sun & Mark H. Ellisman & Bing Ren & Peter J. Campbell & Don W. Cleveland - 142-146 Wetting regulates autophagy of phase-separated compartments and the cytosol
by Jaime Agudo-Canalejo & Sebastian W. Schultz & Haruka Chino & Simona M. Migliano & Chieko Saito & Ikuko Koyama-Honda & Harald Stenmark & Andreas Brech & Alexander I. May & Noboru Mizushima & Roland L. Knorr - 147-151 Systematic analysis of binding of transcription factors to noncoding variants
by Jian Yan & Yunjiang Qiu & André M. Ribeiro dos Santos & Yimeng Yin & Yang E. Li & Nick Vinckier & Naoki Nariai & Paola Benaglio & Anugraha Raman & Xiaoyu Li & Shicai Fan & Joshua Chiou & Fulin Chen & Kelly A. Frazer & Kyle J. Gaulton & Maike Sander & Jussi Taipale & Bing Ren - 152-156 The kinetic landscape of an RNA-binding protein in cells
by Deepak Sharma & Leah L. Zagore & Matthew M. Brister & Xuan Ye & Carlos E. Crespo-Hernández & Donny D. Licatalosi & Eckhard Jankowsky - 157-161 Structure and inhibition mechanism of the human citrate transporter NaCT
by David B. Sauer & Jinmei Song & Bing Wang & Jacob K. Hilton & Nathan K. Karpowich & Joseph A. Mindell & William J. Rice & Da-Neng Wang - 163-164 We’ll meet again: scientists’ post-pandemic wish list
by Chris Woolston - 165-165 Coronavirus diaries: Laughter is the best medicine
by John Tregoning - 166-167 How to get started in quantum computing
by David Matthews - 170-170 My race against time to capture the sounds of ancient rainforests
by James Mitchell Crow
February 2021, Volume 590, Issue 7847
- 529-529 Rich countries should tithe their vaccines
by Gavin Yamey - 535-537 Touch down! NASA’s Mars landing sparks new era of exploration
by Alexandra Witze - 537-538 Million-year-old mammoth genomes shatter record for oldest ancient DNA
by Ewen Callaway - 538-540 COVID vaccines and safety: what the research says
by Ariana Remmel - 540-541 Quantum network is step towards ultrasecure internet
by Davide Castelvecchi - 542-542 Give African research participants more say in genomic data, say scientists
by Linda Nordling - 544-546 Superspreading drives the COVID pandemic — and could help to tame it
by Dyani Lewis - 547-547 George Carruthers (1939–2020)
by Angelina Callahan & Robert R. Meier & David H. DeVorkin - 548-550 Eight priorities for calculating the social cost of carbon
by Gernot Wagner & David Anthoff & Maureen Cropper & Simon Dietz & Kenneth T. Gillingham & Ben Groom & J. Paul Kelleher & Frances C. Moore & James H. Stock - 551-551 Oil licences undermine Norway’s ocean leadership
by Henrik Österblom & Robert Blasiak - 551-551 Hertha Ayrton’s Nature obituary: a monument to sexism in science
by Danita Brandt - 551-551 OECD on climate finance: donors need to step up and enhance reporting
by Simon Buckle - 551-551 Physics in Africa: invest to reform and transform
by Shaaban Said Khalil - 553-554 Signs of self-sustained inflammatory circuits in severe COVID pneumonia
by Kara J. Mould & William J. Janssen - 554-555 Cells use loop extrusion to weave and tie the genome
by Leonid A. Mirny - 556-557 Accelerator-based light sources get a boost
by Alexander Brynes - 557-558 Mutation alters chromatin changes during injury response to drive cancer
by Dane Vassiliadis & Mark A. Dawson - 559-560 Antimatter in the proton is more down than up
by Haiyan Gao - 561-565 The asymmetry of antimatter in the proton
by J. Dove & B. Kerns & R. E. McClellan & S. Miyasaka & D. H. Morton & K. Nagai & S. Prasad & F. Sanftl & M. B. C. Scott & A. S. Tadepalli & C. A. Aidala & J. Arrington & C. Ayuso & C. L. Barker & C. N. Brown & W. C. Chang & A. Chen & D. C. Christian & B. P. Dannowitz & M. Daugherity & M. Diefenthaler & L. El Fassi & D. F. Geesaman & R. Gilman & Y. Goto & L. Guo & R. Guo & T. J. Hague & R. J. Holt & D. Isenhower & E. R. Kinney & N. Kitts & A. Klein & D. W. Kleinjan & Y. Kudo & C. Leung & P.-J. Lin & K. Liu & M. X. Liu & W. Lorenzon & N. C. R. Makins & M. Mesquita Medeiros & P. L. McGaughey & Y. Miyachi & I. Mooney & K. Nakahara & K. Nakano & S. Nara & J.-C. Peng & A. J. Puckett & B. J. Ramson & P. E. Reimer & J. G. Rubin & S. Sawada & T. Sawada & T.-A. Shibata & D. Su & M. Teo & B. G. Tice & R. S. Towell & S. Uemura & S. Watson & S. G. Wang & A. B. Wickes & J. Wu & Z. Xi & Z. Ye - 566-570 Angular momentum generation in nuclear fission
by J. N. Wilson & D. Thisse & M. Lebois & N. Jovančević & D. Gjestvang & R. Canavan & M. Rudigier & D. Étasse & R-B. Gerst & L. Gaudefroy & E. Adamska & P. Adsley & A. Algora & M. Babo & K. Belvedere & J. Benito & G. Benzoni & A. Blazhev & A. Boso & S. Bottoni & M. Bunce & R. Chakma & N. Cieplicka-Oryńczak & S. Courtin & M. L. Cortés & P. Davies & C. Delafosse & M. Fallot & B. Fornal & L. Fraile & A. Gottardo & V. Guadilla & G. Häfner & K. Hauschild & M. Heine & C. Henrich & I. Homm & F. Ibrahim & Ł. W. Iskra & P. Ivanov & S. Jazrawi & A. Korgul & P. Koseoglou & T. Kröll & T. Kurtukian-Nieto & L. Meur & S. Leoni & J. Ljungvall & A. Lopez-Martens & R. Lozeva & I. Matea & K. Miernik & J. Nemer & S. Oberstedt & W. Paulsen & M. Piersa & Y. Popovitch & C. Porzio & L. Qi & D. Ralet & P. H. Regan & K. Rezynkina & V. Sánchez-Tembleque & S. Siem & C. Schmitt & P.-A. Söderström & C. Sürder & G. Tocabens & V. Vedia & D. Verney & N. Warr & B. Wasilewska & J. Wiederhold & M. Yavahchova & F. Zeiser & S. Ziliani - 571-575 Deterministic multi-qubit entanglement in a quantum network
by Youpeng Zhong & Hung-Shen Chang & Audrey Bienfait & Étienne Dumur & Ming-Han Chou & Christopher R. Conner & Joel Grebel & Rhys G. Povey & Haoxiong Yan & David I. Schuster & Andrew N. Cleland - 576-579 Experimental demonstration of the mechanism of steady-state microbunching
by Xiujie Deng & Alexander Chao & Jörg Feikes & Arne Hoehl & Wenhui Huang & Roman Klein & Arnold Kruschinski & Ji Li & Aleksandr Matveenko & Yuriy Petenev & Markus Ries & Chuanxiang Tang & Lixin Yan - 580-586 First return, then explore
by Adrien Ecoffet & Joost Huizinga & Joel Lehman & Kenneth O. Stanley & Jeff Clune - 587-593 Efficient perovskite solar cells via improved carrier management
by Jason J. Yoo & Gabkyung Seo & Matthew R. Chua & Tae Gwan Park & Yongli Lu & Fabian Rotermund & Young-Ki Kim & Chan Su Moon & Nam Joong Jeon & Juan-Pablo Correa-Baena & Vladimir Bulović & Seong Sik Shin & Moungi G. Bawendi & Jangwon Seo - 594-599 Strong tough hydrogels via the synergy of freeze-casting and salting out
by Mutian Hua & Shuwang Wu & Yanfei Ma & Yusen Zhao & Zilin Chen & Imri Frenkel & Joseph Strzalka & Hua Zhou & Xinyuan Zhu & Ximin He - 600-605 Genomic basis of geographical adaptation to soil nitrogen in rice
by Yongqiang Liu & Hongru Wang & Zhimin Jiang & Wei Wang & Ruineng Xu & Qihui Wang & Zhihua Zhang & Aifu Li & Yan Liang & Shujun Ou & Xiujie Liu & Shouyun Cao & Hongning Tong & Yonghong Wang & Feng Zhou & Hong Liao & Bin Hu & Chengcai Chu - 606-611 Evolving schema representations in orbitofrontal ensembles during learning
by Jingfeng Zhou & Chunying Jia & Marlian Montesinos-Cartagena & Matthew P. H. Gardner & Wenhui Zong & Geoffrey Schoenbaum - 612-617 Astrocytes phagocytose adult hippocampal synapses for circuit homeostasis
by Joon-Hyuk Lee & Ji-young Kim & Seulgi Noh & Hyoeun Lee & Se Young Lee & Ji Young Mun & Hyungju Park & Won-Suk Chung - 618-623 Cooperative epithelial phagocytosis enables error correction in the early embryo
by Esteban Hoijman & Hanna-Maria Häkkinen & Queralt Tolosa-Ramon & Senda Jiménez-Delgado & Chris Wyatt & Marta Miret-Cuesta & Manuel Irimia & Andrew Callan-Jones & Stefan Wieser & Verena Ruprecht - 624-629 The Card1 nuclease provides defence during type III CRISPR immunity
by Jakob T. Rostøl & Wei Xie & Vitaly Kuryavyi & Pascal Maguin & Kevin Kao & Ruby Froom & Dinshaw J. Patel & Luciano A. Marraffini - 630-634 Correlates of protection against SARS-CoV-2 in rhesus macaques
by Katherine McMahan & Jingyou Yu & Noe B. Mercado & Carolin Loos & Lisa H. Tostanoski & Abishek Chandrashekar & Jinyan Liu & Lauren Peter & Caroline Atyeo & Alex Zhu & Esther A. Bondzie & Gabriel Dagotto & Makda S. Gebre & Catherine Jacob-Dolan & Zhenfeng Li & Felix Nampanya & Shivani Patel & Laurent Pessaint & Alex Ry & Kelvin Blade & Jake Yalley-Ogunro & Mehtap Cabus & Renita Brown & Anthony Cook & Elyse Teow & Hanne Andersen & Mark G. Lewis & Douglas A. Lauffenburger & Galit Alter & Dan H. Barouch - 635-641 Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia
by Rogan A. Grant & Luisa Morales-Nebreda & Nikolay S. Markov & Suchitra Swaminathan & Melissa Querrey & Estefany R. Guzman & Darryl A. Abbott & Helen K. Donnelly & Alvaro Donayre & Isaac A. Goldberg & Zasu M. Klug & Nicole Borkowski & Ziyan Lu & Hermon Kihshen & Yuliya Politanska & Lango Sichizya & Mengjia Kang & Ali Shilatifard & Chao Qi & Jon W. Lomasney & A. Christine Argento & Jacqueline M. Kruser & Elizabeth S. Malsin & Chiagozie O. Pickens & Sean B. Smith & James M. Walter & Anna E. Pawlowski & Daniel Schneider & Prasanth Nannapaneni & Hiam Abdala-Valencia & Ankit Bharat & Cara J. Gottardi & G. R. Scott Budinger & Alexander V. Misharin & Benjamin D. Singer & Richard G. Wunderink - 642-648 A gene–environment-induced epigenetic program initiates tumorigenesis
by Direna Alonso-Curbelo & Yu-Jui Ho & Cassandra Burdziak & Jesper L. V. Maag & John P. Morris & Rohit Chandwani & Hsuan-An Chen & Kaloyan M. Tsanov & Francisco M. Barriga & Wei Luan & Nilgun Tasdemir & Geulah Livshits & Elham Azizi & Jaeyoung Chun & John E. Wilkinson & Linas Mazutis & Steven D. Leach & Richard Koche & Dana Pe’er & Scott W. Lowe - 649-654 Spatiotemporal dissection of the cell cycle with single-cell proteogenomics
by Diana Mahdessian & Anthony J. Cesnik & Christian Gnann & Frida Danielsson & Lovisa Stenström & Muhammad Arif & Cheng Zhang & Trang Le & Fredric Johansson & Rutger Schutten & Anna Bäckström & Ulrika Axelsson & Peter Thul & Nathan H. Cho & Oana Carja & Mathias Uhlén & Adil Mardinoglu & Charlotte Stadler & Cecilia Lindskog & Burcu Ayoglu & Manuel D. Leonetti & Fredrik Pontén & Devin P. Sullivan & Emma Lundberg - 655-659 Tracking break-induced replication shows that it stalls at roadblocks
by Liping Liu & Zhenxin Yan & Beth A. Osia & Jerzy Twarowski & Luyang Sun & Juraj Kramara & Rosemary S. Lee & Sandeep Kumar & Rajula Elango & Hanzeng Li & Weiwei Dang & Grzegorz Ira & Anna Malkova - 660-665 Loop extrusion as a mechanism for formation of DNA damage repair foci
by Coline Arnould & Vincent Rocher & Anne-Laure Finoux & Thomas Clouaire & Kevin Li & Felix Zhou & Pierre Caron & Philippe. E. Mangeot & Emiliano P. Ricci & Raphaël Mourad & James E. Haber & Daan Noordermeer & Gaëlle Legube - 666-670 Functional refolding of the penetration protein on a non-enveloped virus
by Tobias Herrmann & Raúl Torres & Eric N. Salgado & Cristina Berciu & Daniel Stoddard & Daniela Nicastro & Simon Jenni & Stephen C. Harrison - 671-676 Ubiquitin ligation to F-box protein targets by SCF–RBR E3–E3 super-assembly
by Daniel Horn-Ghetko & David T. Krist & J. Rajan Prabu & Kheewoong Baek & Monique P. C. Mulder & Maren Klügel & Daniel C. Scott & Huib Ovaa & Gary Kleiger & Brenda A. Schulman - 677-677 Pay gap widens between female and male scientists in North America
by Chris Woolston - 678-678 Science outreach in my mother tongue
by Ana Teles & Flávia Viana - 679-681 Closing in on a complete human genome
by Michael Eisenstein - 684-684 Taking graphene out of the laboratory and into the real world
by Chris Woolston
February 2021, Volume 590, Issue 7846
- 35-47 Concerns about phytoplankton bloom trends in global lakes
by Lian Feng & Yanhui Dai & Xuejiao Hou & Yang Xu & Junguo Liu & Chunmiao Zheng - 48-50 Reply to: Concerns about phytoplankton bloom trends in global lakes
by Jeff C. Ho & Anna M. Michalak & Nima Pahlevan - 51-51 Author Correction: Cortical response selectivity derives from strength in numbers of synapses
by Benjamin Scholl & Connon I. Thomas & Melissa A. Ryan & Naomi Kamasawa & David Fitzpatrick - 52-52 Author Correction: Structural basis of assembly of the human T cell receptor–CD3 complex
by De Dong & Lvqin Zheng & Jianquan Lin & Bailing Zhang & Yuwei Zhu & Ningning Li & Shuangyu Xie & Yuhang Wang & Ning Gao & Zhiwei Huang - 53-53 Author Correction: The mutational constraint spectrum quantified from variation in 141,456 humans
by Konrad J. Karczewski & Laurent C. Francioli & Grace Tiao & Beryl B. Cummings & Jessica Alföldi & Qingbo Wang & Ryan L. Collins & Kristen M. Laricchia & Andrea Ganna & Daniel P. Birnbaum & Laura D. Gauthier & Harrison Brand & Matthew Solomonson & Nicholas A. Watts & Daniel Rhodes & Moriel Singer-Berk & Eleina M. England & Eleanor G. Seaby & Jack A. Kosmicki & Raymond K. Walters & Katherine Tashman & Yossi Farjoun & Eric Banks & Timothy Poterba & Arcturus Wang & Cotton Seed & Nicola Whiffin & Jessica X. Chong & Kaitlin E. Samocha & Emma Pierce-Hoffman & Zachary Zappala & Anne H. O’Donnell-Luria & Eric Vallabh Minikel & Ben Weisburd & Monkol Lek & James S. Ware & Christopher Vittal & Irina M. Armean & Louis Bergelson & Kristian Cibulskis & Kristen M. Connolly & Miguel Covarrubias & Stacey Donnelly & Steven Ferriera & Stacey Gabriel & Jeff Gentry & Namrata Gupta & Thibault Jeandet & Diane Kaplan & Christopher Llanwarne & Ruchi Munshi & Sam Novod & Nikelle Petrillo & David Roazen & Valentin Ruano-Rubio & Andrea Saltzman & Molly Schleicher & Jose Soto & Kathleen Tibbetts & Charlotte Tolonen & Gordon Wade & Michael E. Talkowski & Benjamin M. Neale & Mark J. Daly & Daniel G. MacArthur - 54-54 Author Correction: Transcript expression-aware annotation improves rare variant interpretation
by Beryl B. Cummings & Konrad J. Karczewski & Jack A. Kosmicki & Eleanor G. Seaby & Nicholas A. Watts & Moriel Singer-Berk & Jonathan M. Mudge & Juha Karjalainen & F. Kyle Satterstrom & Anne H. O’Donnell-Luria & Timothy Poterba & Cotton Seed & Matthew Solomonson & Jessica Alföldi & Mark J. Daly & Daniel G. MacArthur - 55-55 Author Correction: A structural variation reference for medical and population genetics
by Ryan L. Collins & Harrison Brand & Konrad J. Karczewski & Xuefang Zhao & Jessica Alföldi & Laurent C. Francioli & Amit V. Khera & Chelsea Lowther & Laura D. Gauthier & Harold Wang & Nicholas A. Watts & Matthew Solomonson & Anne O’Donnell-Luria & Alexander Baumann & Ruchi Munshi & Mark Walker & Christopher W. Whelan & Yongqing Huang & Ted Brookings & Ted Sharpe & Matthew R. Stone & Elise Valkanas & Jack Fu & Grace Tiao & Kristen M. Laricchia & Valentin Ruano-Rubio & Christine Stevens & Namrata Gupta & Caroline Cusick & Lauren Margolin & Kent D. Taylor & Henry J. Lin & Stephen S. Rich & Wendy S. Post & Yii-Der Ida Chen & Jerome I. Rotter & Chad Nusbaum & Anthony Philippakis & Eric Lander & Stacey Gabriel & Benjamin M. Neale & Sekar Kathiresan & Mark J. Daly & Eric Banks & Daniel G. MacArthur & Michael E. Talkowski - 56-56 Author Correction: Evaluating drug targets through human loss-of-function genetic variation
by Eric Vallabh Minikel & Konrad J. Karczewski & Hilary C. Martin & Beryl B. Cummings & Nicola Whiffin & Daniel Rhodes & Jessica Alföldi & Richard C. Trembath & David A. Heel & Mark J. Daly & Stuart L. Schreiber & Daniel G. MacArthur - 365-365 At 50, the UN Environment Programme must lead again
by Maria Ivanova - 371-372 ‘Major stones unturned’: COVID origin search must continue after WHO report, say scientists
by Smriti Mallapaty & Amy Maxmen & Ewen Callaway - 372-373 Elation as first Arab Mars mission reaches orbit
by Elizabeth Gibney - 373-373 Illegal CFC emissions have stopped since scientists raised alarm
by Jeff Tollefson - 374-375 How ‘killer’ T cells could boost COVID immunity in face of new variants
by Heidi Ledford - 375-376 Could mixing COVID vaccines boost immune response?
by Heidi Ledford - 376-377 Neanderthal-like ‘mini-brains’ created in lab with CRISPR
by Ariana Remmel - 377-377 This COVID-vaccine designer is tackling vaccine hesitancy — in churches and on Twitter
by Nidhi Subbaraman - 378-381 Mystery gamma rays could help solve age-old lightning puzzle
by Elizabeth Gibney - 382-384 The coronavirus is here to stay — here’s what that means
by Nicky Phillips - 386-388 Variant-proof vaccines — invest now for the next pandemic
by Dennis R. Burton & Eric J. Topol - 389-389 Peace-making: new technologies are no panacea
by Oliver P. Richmond & Gëzim Visoka - 389-389 Tech firms need Black AI scholars and labour rights
by Ifeoma Ajunwa & Sareeta Amrute & Lilly Irani & Winifred R. Poster & Meg Stalcup - 389-389 Involve citizens in climate-policy modelling
by Haris Doukas & Alexandros Nikas - 389-389 Vaccination: keep records secure with blockchain
by Johnson Chun-Sing Cheung - 391-392 High-performance plastic made from renewable oils is chemically recyclable by design
by Charlotte K. Williams & Georgina L. Gregory - 392-394 The role and rule of relatedness in altruism
by Andrew F. G. Bourke - 394-395 Multiple genomes give switchgrass an advantage
by Erik J. Sacks - 396-397 Glowing nanocrystals enable 3D X-ray imaging
by Albano N. Carneiro Neto & Oscar L. Malta - 397-398 Antibodies periodically wax and wane in survivors of Ebola
by Courtney Woolsey & Thomas W. Geisbert - 399-400 An epigenetic tipping point in cancer comes under the microscope
by Martyna W. Sroka & Christopher R. Vakoc - 401-404 Coherent X-ray−optical control of nuclear excitons
by Kilian P. Heeg & Andreas Kaldun & Cornelius Strohm & Christian Ott & Rajagopalan Subramanian & Dominik Lentrodt & Johann Haber & Hans-Christian Wille & Stephan Goerttler & Rudolf Rüffer & Christoph H. Keitel & Ralf Röhlsberger & Thomas Pfeifer & Jörg Evers - 405-409 Localization of lattice dynamics in low-angle twisted bilayer graphene
by Andreij C. Gadelha & Douglas A. A. Ohlberg & Cassiano Rabelo & Eliel G. S. Neto & Thiago L. Vasconcelos & João L. Campos & Jessica S. Lemos & Vinícius Ornelas & Daniel Miranda & Rafael Nadas & Fabiano C. Santana & Kenji Watanabe & Takashi Taniguchi & Benoit Troeye & Michael Lamparski & Vincent Meunier & Viet-Hung Nguyen & Dawid Paszko & Jean-Christophe Charlier & Leonardo C. Campos & Luiz G. Cançado & Gilberto Medeiros-Ribeiro & Ado Jorio - 410-415 High-resolution X-ray luminescence extension imaging
by Xiangyu Ou & Xian Qin & Bolong Huang & Jie Zan & Qinxia Wu & Zhongzhu Hong & Lili Xie & Hongyu Bian & Zhigao Yi & Xiaofeng Chen & Yiming Wu & Xiaorong Song & Juan Li & Qiushui Chen & Huanghao Yang & Xiaogang Liu - 416-422 Self-similar mesocrystals form via interface-driven nucleation and assembly
by Guomin Zhu & Maria L. Sushko & John S. Loring & Benjamin A. Legg & Miao Song & Jennifer A. Soltis & Xiaopeng Huang & Kevin M. Rosso & James J. De Yoreo - 423-427 Closed-loop recycling of polyethylene-like materials
by Manuel Häußler & Marcel Eck & Dario Rothauer & Stefan Mecking - 428-432 A decline in global CFC-11 emissions during 2018−2019
by Stephen A. Montzka & Geoffrey S. Dutton & Robert W. Portmann & Martyn P. Chipperfield & Sean Davis & Wuhu Feng & Alistair J. Manning & Eric Ray & Matthew Rigby & Bradley D. Hall & Carolina Siso & J. David Nance & Paul B. Krummel & Jens Mühle & Dickon Young & Simon O’Doherty & Peter K. Salameh & Christina M. Harth & Ronald G. Prinn & Ray F. Weiss & James W. Elkins & Helen Walter-Terrinoni & Christina Theodoridi - 433-437 A decline in emissions of CFC-11 and related chemicals from eastern China
by Sunyoung Park & Luke M. Western & Takuya Saito & Alison L. Redington & Stephan Henne & Xuekun Fang & Ronald G. Prinn & Alistair J. Manning & Stephen A. Montzka & Paul J. Fraser & Anita L. Ganesan & Christina M. Harth & Jooil Kim & Paul B. Krummel & Qing Liang & Jens Mühle & Simon O’Doherty & Hyeri Park & Mi-Kyung Park & Stefan Reimann & Peter K. Salameh & Ray F. Weiss & Matthew Rigby - 438-444 Genomic mechanisms of climate adaptation in polyploid bioenergy switchgrass
by John T. Lovell & Alice H. MacQueen & Sujan Mamidi & Jason Bonnette & Jerry Jenkins & Joseph D. Napier & Avinash Sreedasyam & Adam Healey & Adam Session & Shengqiang Shu & Kerrie Barry & Stacy Bonos & LoriBeth Boston & Christopher Daum & Shweta Deshpande & Aren Ewing & Paul P. Grabowski & Taslima Haque & Melanie Harrison & Jiming Jiang & Dave Kudrna & Anna Lipzen & Thomas H. Pendergast & Chris Plott & Peng Qi & Christopher A. Saski & Eugene V. Shakirov & David Sims & Manoj Sharma & Rita Sharma & Ada Stewart & Vasanth R. Singan & Yuhong Tang & Sandra Thibivillier & Jenell Webber & Xiaoyu Weng & Melissa Williams & Guohong Albert Wu & Yuko Yoshinaga & Matthew Zane & Li Zhang & Jiyi Zhang & Kathrine D. Behrman & Arvid R. Boe & Philip A. Fay & Felix B. Fritschi & Julie D. Jastrow & John Lloyd-Reilley & Juan Manuel Martínez-Reyna & Roser Matamala & Robert B. Mitchell & Francis M. Rouquette & Pamela Ronald & Malay Saha & Christian M. Tobias & Michael Udvardi & Rod A. Wing & Yanqi Wu & Laura E. Bartley & Michael Casler & Katrien M. Devos & David B. Lowry & Daniel S. Rokhsar & Jane Grimwood & Thomas E. Juenger & Jeremy Schmutz - 445-450 A functional map for diverse forelimb actions within brainstem circuitry
by Ludwig Ruder & Riccardo Schina & Harsh Kanodia & Sara Valencia-Garcia & Chiara Pivetta & Silvia Arber - 451-456 Cell-type-specific asynchronous modulation of PKA by dopamine in learning
by Suk Joon Lee & Bart Lodder & Yao Chen & Tommaso Patriarchi & Lin Tian & Bernardo L. Sabatini - 457-462 In situ mapping identifies distinct vascular niches for myelopoiesis
by Jizhou Zhang & Qingqing Wu & Courtney B. Johnson & Giang Pham & Jeremy M. Kinder & Andre Olsson & Anastasiya Slaughter & Margot May & Benjamin Weinhaus & Angelo D’Alessandro & James Douglas Engel & Jean X. Jiang & J. Matthew Kofron & L. Frank Huang & V. B. Surya Prasath & Sing Sing Way & Nathan Salomonis & H. Leighton Grimes & Daniel Lucas - 463-467 Molecular basis for control of antibiotic production by a bacterial hormone
by Shanshan Zhou & Hussain Bhukya & Nicolas Malet & Peter J. Harrison & Dean Rea & Matthew J. Belousoff & Hariprasad Venugopal & Paulina K. Sydor & Kathryn M. Styles & Lijiang Song & Max J. Cryle & Lona M. Alkhalaf & Vilmos Fülöp & Gregory L. Challis & Christophe Corre - 468-472 Ebola virus antibody decay–stimulation in a high proportion of survivors
by Charlene Adaken & Janet T. Scott & Raman Sharma & Robin Gopal & Steven Dicks & Saidia Niazi & Samreen Ijaz & Tansy Edwards & Catherine C. Smith & Christine P. Cole & Philip Kamara & Osman Kargbo & Heidi A. Doughty & Johan Griensven & Peter W. Horby & Sahr M. Gevao & Foday Sahr & Richard J. Dimelow & Richard S. Tedder & Malcolm G. Semple & William A. Paxton & Georgios Pollakis - 473-479 Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes
by Liliana M. Sanmarco & Michael A. Wheeler & Cristina Gutiérrez-Vázquez & Carolina Manganeli Polonio & Mathias Linnerbauer & Felipe A. Pinho-Ribeiro & Zhaorong Li & Federico Giovannoni & Katelyn V. Batterman & Giulia Scalisi & Stephanie E. J. Zandee & Evelyn S. Heck & Moneera Alsuwailm & Douglas L. Rosene & Burkhard Becher & Isaac M. Chiu & Alexandre Prat & Francisco J. Quintana - 480-485 Creatine kinase B controls futile creatine cycling in thermogenic fat
by Janane F. Rahbani & Anna Roesler & Mohammed F. Hussain & Bozena Samborska & Christien B. Dykstra & Linus Tsai & Mark P. Jedrychowski & Laurent Vergnes & Karen Reue & Bruce M. Spiegelman & Lawrence Kazak - 486-491 Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition
by Yael Cohen-Sharir & James M. McFarland & Mai Abdusamad & Carolyn Marquis & Sara V. Bernhard & Mariya Kazachkova & Helen Tang & Marica R. Ippolito & Kathrin Laue & Johanna Zerbib & Heidi L. H. Malaby & Andrew Jones & Lisa-Marie Stautmeister & Irena Bockaj & René Wardenaar & Nicholas Lyons & Ankur Nagaraja & Adam J. Bass & Diana C. J. Spierings & Floris Foijer & Rameen Beroukhim & Stefano Santaguida & Todd R. Golub & Jason Stumpff & Zuzana Storchová & Uri Ben-David - 492-497 Whole-genome doubling confers unique genetic vulnerabilities on tumour cells
by Ryan J. Quinton & Amanda DiDomizio & Marc A. Vittoria & Kristýna Kotýnková & Carlos J. Ticas & Sheena Patel & Yusuke Koga & Jasmine Vakhshoorzadeh & Nicole Hermance & Taruho S. Kuroda & Neha Parulekar & Alison M. Taylor & Amity L. Manning & Joshua D. Campbell & Neil J. Ganem - 498-503 Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases
by Wanqiu Li & Wei Tian & Gang Yuan & Pujuan Deng & Deepanwita Sengupta & Zhongjun Cheng & Yinghua Cao & Jiahao Ren & Yan Qin & Yuqiao Zhou & Yulin Jia & Or Gozani & Dinshaw J. Patel & Zhanxin Wang - 504-508 Elevated NSD3 histone methylation activity drives squamous cell lung cancer
by Gang Yuan & Natasha M. Flores & Simone Hausmann & Shane M. Lofgren & Vladlena Kharchenko & Maria Angulo-Ibanez & Deepanwita Sengupta & Xiaoyin Lu & Iwona Czaban & Dulat Azhibek & Silvestre Vicent & Wolfgang Fischle & Mariusz Jaremko & Bingliang Fang & Ignacio I. Wistuba & Katrin F. Chua & Jack A. Roth & John D. Minna & Ning-Yi Shao & Łukasz Jaremko & Pawel K. Mazur & Or Gozani - 509-514 Visualization of the mechanosensitive ion channel MscS under membrane tension
by Yixiao Zhang & Csaba Daday & Ruo-Xu Gu & Charles D. Cox & Boris Martinac & Bert L. Groot & Thomas Walz - 515-518 How to shape a productive scientist–artist collaboration
by Virginia Gewin - 520-520 ‘All my art is curiosity-driven’: the garden studio where art and physics collide
by Amber Dance
February 2021, Volume 590, Issue 7845
- 31-33 Author Correction: Innervation of thermogenic adipose tissue via a calsyntenin 3β–S100b axis
by Xing Zeng & Mengchen Ye & Jon M. Resch & Mark P. Jedrychowski & Bo Hu & Bradford B. Lowell & David D. Ginty & Bruce M. Spiegelman - 34-34 Publisher Correction: VEGF-C-driven lymphatic drainage enables immunosurveillance of brain tumours
by Eric Song & Tianyang Mao & Huiping Dong & Ligia Simoes Braga Boisserand & Salli Antila & Marcus Bosenberg & Kari Alitalo & Jean-Leon Thomas & Akiko Iwasaki - 185-185 Test behavioural nudges to boost COVID immunization
by Mitesh Patel - 191-192 What’s the risk of dying from a fast-spreading COVID-19 variant?
by Smriti Mallapaty - 192-193 Tracking QAnon: how Trump turned conspiracy-theory research upside down
by Jeff Tollefson - 194-195 COVID’s mental-health toll: how scientists are tracking a surge in depression
by Alison Abbott - 195-196 Scientists call for fully open sharing of coronavirus genome data
by Richard Van Noorden - 196-196 AI maths whiz creates tough new problems for humans to solve
by Davide Castelvecchi - 197-197 Vaccines are curbing COVID: Data from Israel show drop in infections
by Smriti Mallapaty - 198-201 The broken promise that undermines human genome research
by Kendall Powell - 202-205 Rapid coronavirus tests: a guide for the perplexed
by Giorgia Guglielmi - 206-207 Outstanding reportage from the front lines of geoengineering
by Gaia Vince - 209-211 Sequence three million genomes across Africa
by Ambroise Wonkam - 212-215 A wealth of discovery built on the Human Genome Project — by the numbers
by Alexander J. Gates & Deisy Morselli Gysi & Manolis Kellis & Albert-László Barabási - 217-218 Breaking through the unknowns of the human reference genome
by Karen H. Miga - 218-219 How the human genome transformed study of rare diseases
by Fowzan S. Alkuraya - 220-221 From one human genome to a complex tapestry of ancestry
by Charles N. Rotimi & Adebowale A. Adeyemo - 221-223 New-found brake calibrates insulin action in β-cells
by Rohit N. Kulkarni - 223-224 Neuroprosthetic device maintains blood pressure after spinal cord injury
by Patrice G. Guyenet - 224-226 Lend an ear to a classic tale of mammalian evolution
by Simone Hoffmann - 226-227 Shedding squeezed light on dark matter
by Igor G. Irastorza - 229-237 Origins of modern human ancestry
by Anders Bergström & Chris Stringer & Mateja Hajdinjak & Eleanor M. L. Scerri & Pontus Skoglund - 238-242 A quantum enhanced search for dark matter axions
by K. M. Backes & D. A. Palken & S. Al Kenany & B. M. Brubaker & S. B. Cahn & A. Droster & Gene C. Hilton & Sumita Ghosh & H. Jackson & S. K. Lamoreaux & A. F. Leder & K. W. Lehnert & S. M. Lewis & M. Malnou & R. H. Maruyama & N. M. Rapidis & M. Simanovskaia & Sukhman Singh & D. H. Speller & I. Urdinaran & Leila R. Vale & E. C. Assendelft & K. Bibber & H. Wang - 243-248 Protecting a bosonic qubit with autonomous quantum error correction
by Jeffrey M. Gertler & Brian Baker & Juliang Li & Shruti Shirol & Jens Koch & Chen Wang - 249-255 Tunable strongly coupled superconductivity in magic-angle twisted trilayer graphene
by Jeong Min Park & Yuan Cao & Kenji Watanabe & Takashi Taniguchi & Pablo Jarillo-Herrero - 256-261 A universal 3D imaging sensor on a silicon photonics platform
by Christopher Rogers & Alexander Y. Piggott & David J. Thomson & Robert F. Wiser & Ion E. Opris & Steven A. Fortune & Andrew J. Compston & Alexander Gondarenko & Fanfan Meng & Xia Chen & Graham T. Reed & Remus Nicolaescu - 262-267 Facile route to bulk ultrafine-grain steels for high strength and ductility
by Junheng Gao & Suihe Jiang & Huairuo Zhang & Yuhe Huang & Dikai Guan & Yidong Xu & Shaokang Guan & Leonid A. Bendersky & Albert V. Davydov & Yuan Wu & Huihui Zhu & Yandong Wang & Zhaoping Lu & W. Mark Rainforth - 268-274 Thermally reconfigurable monoclinic nematic colloidal fluids
by Haridas Mundoor & Jin-Sheng Wu & Henricus H. Wensink & Ivan I. Smalyukh - 275-278 Complex structures arising from the self-assembly of a simple organic salt
by Riccardo Montis & Luca Fusaro & Andrea Falqui & Michael B. Hursthouse & Nikolay Tumanov & Simon J. Coles & Terry L. Threlfall & Peter N. Horton & Rachid Sougrat & Anaïs Lafontaine & Gérard Coquerel & A. David Rae - 279-283 A monotreme-like auditory apparatus in a Middle Jurassic haramiyidan
by Junyou Wang & John R. Wible & Bin Guo & Sarah L. Shelley & Han Hu & Shundong Bi - 284-289 Giant lungfish genome elucidates the conquest of land by vertebrates
by Axel Meyer & Siegfried Schloissnig & Paolo Franchini & Kang Du & Joost M. Woltering & Iker Irisarri & Wai Yee Wong & Sergej Nowoshilow & Susanne Kneitz & Akane Kawaguchi & Andrej Fabrizius & Peiwen Xiong & Corentin Dechaud & Herman P. Spaink & Jean-Nicolas Volff & Oleg Simakov & Thorsten Burmester & Elly M. Tanaka & Manfred Schartl - 290-299 Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program
by Daniel Taliun & Daniel N. Harris & Michael D. Kessler & Jedidiah Carlson & Zachary A. Szpiech & Raul Torres & Sarah A. Gagliano Taliun & André Corvelo & Stephanie M. Gogarten & Hyun Min Kang & Achilleas N. Pitsillides & Jonathon LeFaive & Seung-been Lee & Xiaowen Tian & Brian L. Browning & Sayantan Das & Anne-Katrin Emde & Wayne E. Clarke & Douglas P. Loesch & Amol C. Shetty & Thomas W. Blackwell & Albert V. Smith & Quenna Wong & Xiaoming Liu & Matthew P. Conomos & Dean M. Bobo & François Aguet & Christine Albert & Alvaro Alonso & Kristin G. Ardlie & Dan E. Arking & Stella Aslibekyan & Paul L. Auer & John Barnard & R. Graham Barr & Lucas Barwick & Lewis C. Becker & Rebecca L. Beer & Emelia J. Benjamin & Lawrence F. Bielak & John Blangero & Michael Boehnke & Donald W. Bowden & Jennifer A. Brody & Esteban G. Burchard & Brian E. Cade & James F. Casella & Brandon Chalazan & Daniel I. Chasman & Yii-Der Ida Chen & Michael H. Cho & Seung Hoan Choi & Mina K. Chung & Clary B. Clish & Adolfo Correa & Joanne E. Curran & Brian Custer & Dawood Darbar & Michelle Daya & Mariza Andrade & Dawn L. DeMeo & Susan K. Dutcher & Patrick T. Ellinor & Leslie S. Emery & Celeste Eng & Diane Fatkin & Tasha Fingerlin & Lukas Forer & Myriam Fornage & Nora Franceschini & Christian Fuchsberger & Stephanie M. Fullerton & Soren Germer & Mark T. Gladwin & Daniel J. Gottlieb & Xiuqing Guo & Michael E. Hall & Jiang He & Nancy L. Heard-Costa & Susan R. Heckbert & Marguerite R. Irvin & Jill M. Johnsen & Andrew D. Johnson & Robert Kaplan & Sharon L. R. Kardia & Tanika Kelly & Shannon Kelly & Eimear E. Kenny & Douglas P. Kiel & Robert Klemmer & Barbara A. Konkle & Charles Kooperberg & Anna Köttgen & Leslie A. Lange & Jessica Lasky-Su & Daniel Levy & Xihong Lin & Keng-Han Lin & Chunyu Liu & Ruth J. F. Loos & Lori Garman & Robert Gerszten & Steven A. Lubitz & Kathryn L. Lunetta & Angel C. Y. Mak & Ani Manichaikul & Alisa K. Manning & Rasika A. Mathias & David D. McManus & Stephen T. McGarvey & James B. Meigs & Deborah A. Meyers & Julie L. Mikulla & Mollie A. Minear & Braxton D. Mitchell & Sanghamitra Mohanty & May E. Montasser & Courtney Montgomery & Alanna C. Morrison & Joanne M. Murabito & Andrea Natale & Pradeep Natarajan & Sarah C. Nelson & Kari E. North & Jeffrey R. O’Connell & Nicholette D. Palmer & Nathan Pankratz & Gina M. Peloso & Patricia A. Peyser & Jacob Pleiness & Wendy S. Post & Bruce M. Psaty & D. C. Rao & Susan Redline & Alexander P. Reiner & Dan Roden & Jerome I. Rotter & Ingo Ruczinski & Chloé Sarnowski & Sebastian Schoenherr & David A. Schwartz & Jeong-Sun Seo & Sudha Seshadri & Vivien A. Sheehan & Wayne H. Sheu & M. Benjamin Shoemaker & Nicholas L. Smith & Jennifer A. Smith & Nona Sotoodehnia & Adrienne M. Stilp & Weihong Tang & Kent D. Taylor & Marilyn Telen & Timothy A. Thornton & Russell P. Tracy & David J. Berg & Ramachandran S. Vasan & Karine A. Viaud-Martinez & Scott Vrieze & Daniel E. Weeks & Bruce S. Weir & Scott T. Weiss & Lu-Chen Weng & Cristen J. Willer & Yingze Zhang & Xutong Zhao & Donna K. Arnett & Allison E. Ashley-Koch & Kathleen C. Barnes & Eric Boerwinkle & Stacey Gabriel & Richard Gibbs & Kenneth M. Rice & Stephen S. Rich & Edwin K. Silverman & Pankaj Qasba & Weiniu Gan & George J. Papanicolaou & Deborah A. Nickerson & Sharon R. Browning & Michael C. Zody & Sebastian Zöllner & James G. Wilson & L. Adrienne Cupples & Cathy C. Laurie & Cashell E. Jaquish & Ryan D. Hernandez & Timothy D. O’Connor & Gonçalo R. Abecasis - 300-307 Regulatory genomic circuitry of human disease loci by integrative epigenomics
by Carles A. Boix & Benjamin T. James & Yongjin P. Park & Wouter Meuleman & Manolis Kellis - 308-314 Neuroprosthetic baroreflex controls haemodynamics after spinal cord injury
by Jordan W. Squair & Matthieu Gautier & Lois Mahe & Jan Elaine Soriano & Andreas Rowald & Arnaud Bichat & Newton Cho & Mark A. Anderson & Nicholas D. James & Jerome Gandar & Anthony V. Incognito & Giuseppe Schiavone & Zoe K. Sarafis & Achilleas Laskaratos & Kay Bartholdi & Robin Demesmaeker & Salif Komi & Charlotte Moerman & Bita Vaseghi & Berkeley Scott & Ryan Rosentreter & Claudia Kathe & Jimmy Ravier & Laura McCracken & Xiaoyang Kang & Nicolas Vachicouras & Florian Fallegger & Ileana Jelescu & YunLong Cheng & Qin Li & Rik Buschman & Nicolas Buse & Tim Denison & Sean Dukelow & Rebecca Charbonneau & Ian Rigby & Steven K. Boyd & Philip J. Millar & Eduardo Martin Moraud & Marco Capogrosso & Fabien B. Wagner & Quentin Barraud & Erwan Bezard & Stéphanie P. Lacour & Jocelyne Bloch & Grégoire Courtine & Aaron A. Phillips - 315-319 Antidepressant actions of ketamine engage cell-specific translation via eIF4E
by Argel Aguilar-Valles & Danilo De Gregorio & Edna Matta-Camacho & Mohammad J. Eslamizade & Abdessattar Khlaifia & Agnieszka Skaleka & Martha Lopez-Canul & Angelica Torres-Berrio & Sara Bermudez & Gareth M. Rurak & Stephanie Simard & Natalina Salmaso & Gabriella Gobbi & Jean-Claude Lacaille & Nahum Sonenberg - 320-325 A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate
by Lorena Sanchez-Felipe & Thomas Vercruysse & Sapna Sharma & Ji Ma & Viktor Lemmens & Dominique Van Looveren & Mahadesh Prasad Arkalagud Javarappa & Robbert Boudewijns & Bert Malengier-Devlies & Laurens Liesenborghs & Suzanne J. F. Kaptein & Carolien De Keyzer & Lindsey Bervoets & Sarah Debaveye & Madina Rasulova & Laura Seldeslachts & Li-Hsin Li & Sander Jansen & Michael Bright Yakass & Babs E. Verstrepen & Kinga P. Böszörményi & Gwendoline Kiemenyi-Kayere & Nikki van Driel & Osbourne Quaye & Xin Zhang & Sebastiaan ter Horst & Niraj Mishra & Ward Deboutte & Jelle Matthijnssens & Lotte Coelmont & Corinne Vandermeulen & Elisabeth Heylen & Valentijn Vergote & Dominique Schols & Zhongde Wang & Willy Bogers & Thijs Kuiken & Ernst Verschoor & Christopher Cawthorne & Koen Van Laere & Ghislain Opdenakker & Greetje Vande Velde & Birgit Weynand & Dirk E. Teuwen & Patrick Matthys & Johan Neyts & Hendrik Thibaut & Kai Dallmeier - 326-331 Inceptor counteracts insulin signalling in β-cells to control glycaemia
by Ansarullah & Chirag Jain & Fataneh Fathi Far & Sarah Homberg & Katharina Wißmiller & Felizitas Gräfin Hahn & Aurelia Raducanu & Silvia Schirge & Michael Sterr & Sara Bilekova & Johanna Siehler & Julius Wiener & Lena Oppenländer & Amir Morshedi & Aimée Bastidas-Ponce & Gustav Collden & Martin Irmler & Johannes Beckers & Annette Feuchtinger & Michal Grzybek & Christin Ahlbrecht & Regina Feederle & Oliver Plettenburg & Timo D. Müller & Matthias Meier & Matthias H. Tschöp & Ünal Coskun & Heiko Lickert - 332-337 Anti-tumour immunity induces aberrant peptide presentation in melanoma
by Osnat Bartok & Abhijeet Pataskar & Remco Nagel & Maarja Laos & Eden Goldfarb & Deborah Hayoun & Ronen Levy & Pierre-Rene Körner & Inger Z. M. Kreuger & Julien Champagne & Esther A. Zaal & Onno B. Bleijerveld & Xinyao Huang & Juliana Kenski & Jennifer Wargo & Alexander Brandis & Yishai Levin & Orel Mizrahi & Michal Alon & Sacha Lebon & Weiwen Yang & Morten M. Nielsen & Noam Stern-Ginossar & Maarten Altelaar & Celia R. Berkers & Tamar Geiger & Daniel S. Peeper & Johanna Olweus & Yardena Samuels & Reuven Agami - 338-343 Loop extrusion mediates physiological Igh locus contraction for RAG scanning
by Hai-Qiang Dai & Hongli Hu & Jiangman Lou & Adam Yongxin Ye & Zhaoqing Ba & Xuefei Zhang & Yiwen Zhang & Lijuan Zhao & Hye Suk Yoon & Aimee M. Chapdelaine-Williams & Nia Kyritsis & Huan Chen & Kerstin Johnson & Sherry Lin & Andrea Conte & Rafael Casellas & Cheng-Sheng Lee & Frederick W. Alt - 344-350 Integrated spatial genomics reveals global architecture of single nuclei
by Yodai Takei & Jina Yun & Shiwei Zheng & Noah Ollikainen & Nico Pierson & Jonathan White & Sheel Shah & Julian Thomassie & Shengbao Suo & Chee-Huat Linus Eng & Mitchell Guttman & Guo-Cheng Yuan & Long Cai - 351-353 How the arts can help you to craft a successful research career
by Amber Dance - 356-356 Building a university to deliver work-ready engineers
by Chris Woolston
February 2021, Volume 590, Issue 7844
- 1-2 Issues with combining incompatible and sterile insect techniques
by Riccardo Moretti & Maurizio Calvitti - 3-5 Reply to: Issues with combining incompatible and sterile insect techniques
by Yongjun Li & Luke Anthony Baton & Dongjing Zhang & Jérémy Bouyer & Andrew G. Parker & Ary A. Hoffmann & Lee Ching Ng & Cheong Huat Tan & Zhiyong Xi - 6-7 On the measured dielectric constant of amorphous boron nitride
by Lei Li & Xiang Ming Chen - 8-10 Reply to: On the measured dielectric constant of amorphous boron nitride
by Seokmo Hong & Min-Hyun Lee & Sang Won Kim & Chang-Seok Lee & Kyung Yeol Ma & Gwangwoo Kim & Seong In Yoon & Aleandro Antidormi & Stephan Roche & Hyeon-Jin Shin & Manish Chhowalla & Hyeon Suk Shin - 9-9 Rethink how we plan research to shrink COVID health disparities
by Lisa Cooper - 11-11 Author Correction: Suppression of a SARS-CoV-2 outbreak in the Italian municipality of Vo’
by Enrico Lavezzo & Elisa Franchin & Constanze Ciavarella & Gina Cuomo-Dannenburg & Luisa Barzon & Claudia Vecchio & Lucia Rossi & Riccardo Manganelli & Arianna Loregian & Nicolò Navarin & Davide Abate & Manuela Sciro & Stefano Merigliano & Ettore Canale & Maria Cristina Vanuzzo & Valeria Besutti & Francesca Saluzzo & Francesco Onelia & Monia Pacenti & Saverio G. Parisi & Giovanni Carretta & Daniele Donato & Luciano Flor & Silvia Cocchio & Giulia Masi & Alessandro Sperduti & Lorenzo Cattarino & Renato Salvador & Michele Nicoletti & Federico Caldart & Gioele Castelli & Eleonora Nieddu & Beatrice Labella & Ludovico Fava & Matteo Drigo & Katy A. M. Gaythorpe & Alessandra R. Brazzale & Stefano Toppo & Marta Trevisan & Vincenzo Baldo & Christl A. Donnelly & Neil M. Ferguson & Ilaria Dorigatti & Andrea Crisanti - 12-12 Author Correction: Clustered versus catastrophic global vertebrate declines
by Brian Leung & Anna L. Hargreaves & Dan A. Greenberg & Brian McGill & Maria Dornelas & Robin Freeman - 14-14 Publisher Correction: Stellar clustering shapes the architecture of planetary systems
by Andrew J. Winter & J. M. Diederik Kruijssen & Steven N. Longmore & Mélanie Chevance - 15-15 Publisher Correction: Integrated optical multi-ion quantum logic
by Karan K. Mehta & Chi Zhang & Maciej Malinowski & Thanh-Long Nguyen & Martin Stadler & Jonathan P. Home - 15-16 How to redesign COVID vaccines so they protect against variants
by Ewen Callaway & Heidi Ledford - 16-16 Publisher Correction: Filling metal–organic framework mesopores with TiO2 for CO2 photoreduction
by Zhuo Jiang & Xiaohui Xu & Yanhang Ma & Hae Sung Cho & Deng Ding & Chao Wang & Jie Wu & Peter Oleynikov & Mei Jia & Jun Cheng & Yi Zhou & Osamu Terasaki & Tianyou Peng & Ling Zan & Hexiang Deng - 17-17 Novavax offers first evidence that COVID vaccines protect people against variants
by Ewen Callaway & Smriti Mallapaty - 17-17 Publisher Correction: COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses
by Ugur Sahin & Alexander Muik & Evelyna Derhovanessian & Isabel Vogler & Lena M. Kranz & Mathias Vormehr & Alina Baum & Kristen Pascal & Jasmin Quandt & Daniel Maurus & Sebastian Brachtendorf & Verena Lörks & Julian Sikorski & Rolf Hilker & Dirk Becker & Ann-Kathrin Eller & Jan Grützner & Carsten Boesler & Corinna Rosenbaum & Marie-Cristine Kühnle & Ulrich Luxemburger & Alexandra Kemmer-Brück & David Langer & Martin Bexon & Stefanie Bolte & Katalin Karikó & Tania Palanche & Boris Fischer & Armin Schultz & Pei-Yong Shi & Camila Fontes-Garfias & John L. Perez & Kena A. Swanson & Jakob Loschko & Ingrid L. Scully & Mark Cutler & Warren Kalina & Christos A. Kyratsous & David Cooper & Philip R. Dormitzer & Kathrin U. Jansen & Özlem Türeci - 18-18 Publisher Correction: Seismic evidence for partial melt below tectonic plates
by Eric Debayle & Thomas Bodin & Stéphanie Durand & Yanick Ricard - 18-19 Biden’s ambitious COVID plan: what scientists think
by Amy Maxmen & Nidhi Subbaraman - 19-19 Publisher Correction: Integrated multi-wavelength control of an ion qubit
by R. J. Niffenegger & J. Stuart & C. Sorace-Agaskar & D. Kharas & S. Bramhavar & C. D. Bruzewicz & W. Loh & R. T. Maxson & R. McConnell & D. Reens & G. N. West & J. M. Sage & J. Chiaverini - 19-20 Life on Venus claim faces strongest challenge yet
by Alexandra Witze - 20-20 Publisher Correction: The genomic landscapes of individual melanocytes from human skin
by Jessica Tang & Eleanor Fewings & Darwin Chang & Hanlin Zeng & Shanshan Liu & Aparna Jorapur & Rachel L. Belote & Andrew S. McNeal & Tuyet M. Tan & Iwei Yeh & Sarah T. Arron & Robert L. Judson-Torres & Boris C. Bastian & A. Hunter Shain - 20-21 Famed Chinese immunologist cleared of plagiarism and fraud
by David Cyranoski - 21-21 Publisher Correction: Toughening mechanisms of the elytra of the diabolical ironclad beetle
by Jesus Rivera & Maryam Sadat Hosseini & David Restrepo & Satoshi Murata & Drago Vasile & Dilworth Y. Parkinson & Harold S. Barnard & Atsushi Arakaki & Pablo Zavattieri & David Kisailus - 22-22 Publisher Correction: A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures
by Kenneth H. Dinnon & Sarah R. Leist & Alexandra Schäfer & Caitlin E. Edwards & David R. Martinez & Stephanie A. Montgomery & Ande West & Boyd L. Yount & Yixuan J. Hou & Lily E. Adams & Kendra L. Gully & Ariane J. Brown & Emily Huang & Matthew D. Bryant & Ingrid C. Choong & Jeffrey S. Glenn & Lisa E. Gralinski & Timothy P. Sheahan & Ralph S. Baric - 22-25 How gut microbes could drive brain disorders
by Cassandra Willyard - 23-23 Publisher Correction: A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity
by Jingyun Yang & Wei Wang & Zimin Chen & Shuaiyao Lu & Fanli Yang & Zhenfei Bi & Linlin Bao & Fei Mo & Xue Li & Yong Huang & Weiqi Hong & Yun Yang & Yuan Zhao & Fei Ye & Sheng Lin & Wei Deng & Hua Chen & Hong Lei & Ziqi Zhang & Min Luo & Hong Gao & Yue Zheng & Yanqiu Gong & Xiaohua Jiang & Yanfeng Xu & Qi Lv & Dan Li & Manni Wang & Fengdi Li & Shunyi Wang & Guanpeng Wang & Pin Yu & Yajin Qu & Li Yang & Hongxin Deng & Aiping Tong & Jiong Li & Zhenling Wang & Jinliang Yang & Guobo Shen & Zhiwei Zhao & Yuhua Li & Jingwen Luo & Hongqi Liu & Wenhai Yu & Mengli Yang & Jingwen Xu & Junbin Wang & Haiyan Li & Haixuan Wang & Dexuan Kuang & Panpan Lin & Zhengtao Hu & Wei Guo & Wei Cheng & Yanlin He & Xiangrong Song & Chong Chen & Zhihong Xue & Shaohua Yao & Lu Chen & Xuelei Ma & Siyuan Chen & Maling Gou & Weijin Huang & Youchun Wang & Changfa Fan & Zhixin Tian & Ming Shi & Fu-Sheng Wang & Lunzhi Dai & Min Wu & Gen Li & Guangyu Wang & Yong Peng & Zhiyong Qian & Canhua Huang & Johnson Yiu-Nam Lau & Zhenglin Yang & Yuquan Wei & Xiaobo Cen & Xiaozhong Peng & Chuan Qin & Kang Zhang & Guangwen Lu & Xiawei Wei - 24-24 Publisher Correction: ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques
by Neeltje Doremalen & Teresa Lambe & Alexandra Spencer & Sandra Belij-Rammerstorfer & Jyothi N. Purushotham & Julia R. Port & Victoria A. Avanzato & Trenton Bushmaker & Amy Flaxman & Marta Ulaszewska & Friederike Feldmann & Elizabeth R. Allen & Hannah Sharpe & Jonathan Schulz & Myndi Holbrook & Atsushi Okumura & Kimberly Meade-White & Lizzette Pérez-Pérez & Nick J. Edwards & Daniel Wright & Cameron Bissett & Ciaran Gilbride & Brandi N. Williamson & Rebecca Rosenke & Dan Long & Alka Ishwarbhai & Reshma Kailath & Louisa Rose & Susan Morris & Claire Powers & Jamie Lovaglio & Patrick W. Hanley & Dana Scott & Greg Saturday & Emmie Wit & Sarah C. Gilbert & Vincent J. Munster - 25-25 Publisher Correction: Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques
by Noe B. Mercado & Roland Zahn & Frank Wegmann & Carolin Loos & Abishek Chandrashekar & Jingyou Yu & Jinyan Liu & Lauren Peter & Katherine McMahan & Lisa H. Tostanoski & Xuan He & David R. Martinez & Lucy Rutten & Rinke Bos & Danielle Manen & Jort Vellinga & Jerome Custers & Johannes P. Langedijk & Ted Kwaks & Mark J. G. Bakkers & David Zuijdgeest & Sietske K. Rosendahl Huber & Caroline Atyeo & Stephanie Fischinger & John S. Burke & Jared Feldman & Blake M. Hauser & Timothy M. Caradonna & Esther A. Bondzie & Gabriel Dagotto & Makda S. Gebre & Emily Hoffman & Catherine Jacob-Dolan & Marinela Kirilova & Zhenfeng Li & Zijin Lin & Shant H. Mahrokhian & Lori F. Maxfield & Felix Nampanya & Ramya Nityanandam & Joseph P. Nkolola & Shivani Patel & John D. Ventura & Kaylee Verrington & Huahua Wan & Laurent Pessaint & Alex Ry & Kelvin Blade & Amanda Strasbaugh & Mehtap Cabus & Renita Brown & Anthony Cook & Serge Zouantchangadou & Elyse Teow & Hanne Andersen & Mark G. Lewis & Yongfei Cai & Bing Chen & Aaron G. Schmidt & R. Keith Reeves & Ralph S. Baric & Douglas A. Lauffenburger & Galit Alter & Paul Stoffels & Mathai Mammen & Johan Hoof & Hanneke Schuitemaker & Dan H. Barouch - 26-26 Publisher Correction: Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults
by Mark J. Mulligan & Kirsten E. Lyke & Nicholas Kitchin & Judith Absalon & Alejandra Gurtman & Stephen Lockhart & Kathleen Neuzil & Vanessa Raabe & Ruth Bailey & Kena A. Swanson & Ping Li & Kenneth Koury & Warren Kalina & David Cooper & Camila Fontes-Garfias & Pei-Yong Shi & Özlem Türeci & Kristin R. Tompkins & Edward E. Walsh & Robert Frenck & Ann R. Falsey & Philip R. Dormitzer & William C. Gruber & Uğur Şahin & Kathrin U. Jansen - 26-28 COVID-19 rarely spreads through surfaces. So why are we still deep cleaning?
by Dyani Lewis - 27-27 Publisher Correction: Immune-evasive human islet-like organoids ameliorate diabetes
by Eiji Yoshihara & Carolyn O’Connor & Emanuel Gasser & Zong Wei & Tae Gyu Oh & Tiffany W. Tseng & Dan Wang & Fritz Cayabyab & Yang Dai & Ruth T. Yu & Christopher Liddle & Annette R. Atkins & Michael Downes & Ronald M. Evans - 28-28 Publisher Correction: A single-cell transcriptome atlas of marsupial embryogenesis and X inactivation
by Shantha K. Mahadevaiah & Mahesh N. Sangrithi & Takayuki Hirota & James M. A. Turner - 29-29 Publisher Correction: Regulation of the MLH1–MLH3 endonuclease in meiosis
by Elda Cannavo & Aurore Sanchez & Roopesh Anand & Lepakshi Ranjha & Jannik Hugener & Céline Adam & Ananya Acharya & Nicolas Weyland & Xavier Aran-Guiu & Jean-Baptiste Charbonnier & Eva R. Hoffmann & Valérie Borde & Joao Matos & Petr Cejka - 29-31 Rogue antibodies could be driving severe COVID-19
by Roxanne Khamsi - 30-30 Publisher Correction: PCNA activates the MutLγ endonuclease to promote meiotic crossing over
by Dhananjaya S. Kulkarni & Shannon N. Owens & Masayoshi Honda & Masaru Ito & Ye Yang & Mary W. Corrigan & Lan Chen & Aric L. Quan & Neil Hunter - 33-35 Q&A: How cartoonists skewer tensions between science and society
by Alexandra Witze - 35-35 The key to social change, free will on trial, and an astrophysicist on a visit from extraterrestrials: Books in brief
by Andrew Robinson - 36-36 TL;DR: how well do machines summarize our work?
by James P. Bagrow - 36-36 Open access pay-for-review option — ethical question
by Silvo Conticello - 36-36 Vaccine sprint predicted a decade ago
by Rino Rappuoli - 36-36 COVID-19 vaccines: call for global push to maintain efficacy
by Klaus Stöhr & Nancy Cox - 37-38 The Arctic Ocean might have been filled with freshwater during ice ages
by Sharon Hoffmann - 38-39 An estimation of undetected COVID cases in France
by Jeffrey Shaman - 40-41 Machine learning made easy for optimizing chemical reactions
by Jason E. Hein - 41-43 Food for thought about the immune drivers of gut pain
by Stuart M. Brierley - 43-44 A molecular handbook for human development
by Felicia Kuperwaser & Itai Yanai - 44-45 Reversal of immune-cell shutdown protects the ageing brain
by Jonas J. Neher - 47-56 Developing fibrillated cellulose as a sustainable technological material
by Tian Li & Chaoji Chen & Alexandra H. Brozena & J. Y. Zhu & Lixian Xu & Carlos Driemeier & Jiaqi Dai & Orlando J. Rojas & Akira Isogai & Lars Wågberg & Liangbing Hu - 57-66 Function and regulation of the divisome for mitochondrial fission
by Felix Kraus & Krishnendu Roy & Thomas J. Pucadyil & Michael T. Ryan - 67-73 Generating conjectures on fundamental constants with the Ramanujan Machine
by Gal Raayoni & Shahar Gottlieb & Yahel Manor & George Pisha & Yoav Harris & Uri Mendlovic & Doron Haviv & Yaron Hadad & Ido Kaminer - 74-79 Antiferromagnetic half-skyrmions and bimerons at room temperature
by Hariom Jani & Jheng-Cyuan Lin & Jiahao Chen & Jack Harrison & Francesco Maccherozzi & Jonathon Schad & Saurav Prakash & Chang-Beom Eom & A. Ariando & T. Venkatesan & Paolo G. Radaelli - 80-84 Viscoelastic control of spatiotemporal order in bacterial active matter
by Song Liu & Suraj Shankar & M. Cristina Marchetti & Yilin Wu - 85-88 Structural and spectroscopic characterization of an einsteinium complex
by Korey P. Carter & Katherine M. Shield & Kurt F. Smith & Zachary R. Jones & Jennifer N. Wacker & Leticia Arnedo-Sanchez & Tracy M. Mattox & Liane M. Moreau & Karah E. Knope & Stosh A. Kozimor & Corwin H. Booth & Rebecca J. Abergel - 89-96 Bayesian reaction optimization as a tool for chemical synthesis
by Benjamin J. Shields & Jason Stevens & Jun Li & Marvin Parasram & Farhan Damani & Jesus I. Martinez Alvarado & Jacob M. Janey & Ryan P. Adams & Abigail G. Doyle - 97-102 Glacial episodes of a freshwater Arctic Ocean covered by a thick ice shelf
by Walter Geibert & Jens Matthiessen & Ingrid Stimac & Jutta Wollenburg & Ruediger Stein