Content
October 2025, Volume 646, Issue 8087
- 1204-1213 Monoclonal antibodies protect against pandrug-resistant Klebsiella pneumoniae
by Emanuele Roscioli & Vittoria Zucconi Galli Fonseca & Soraya Soledad Bosch & Ida Paciello & Giuseppe Maccari & Giulia Cardinali & Giampiero Batani & Samuele Stazzoni & Giusy Tiseo & Cesira Giordano & Shen Yuwei & Laura Capoccia & Dario Cardamone & Matteo Ridelfi & Marco Troisi & Noemi Manganaro & Chiara Mugnaini & Concetta De Santi & Annalisa Ciabattini & Linda Cerofolini & Marco Fragai & Danilo Licastro & Kelly Wyres & Laurent Dortet & Simona Barnini & David P. Nicolau & Francesco Menichetti & Marco Falcone & Kamilia Abdelraouf & Claudia Sala & Anna Kabanova & Rino Rappuoli - 1214-1222 Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumours
by Samarth Hegde & Bruno Giotti & Brian Y. Soong & Laszlo Halasz & Jessica Berichel & Maximilian M. Schaefer & Benoit Kloeckner & Raphaël Mattiuz & Matthew D. Park & Assaf Magen & Adam Marks & Meriem Belabed & Pauline Hamon & Theodore Chin & Leanna Troncoso & Juliana J. Lee & Kaili Fan & Dughan Ahimovic & Michael J. Bale & Kai Nie & Grace Chung & Darwin D’souza & Krista Angeliadis & Seunghee Kim-Schulze & Raja M. Flores & Andrew J. Kaufman & Florent Ginhoux & Jason D. Buenrostro & Steven Z. Josefowicz & Alexander M. Tsankov & Thomas U. Marron & Sai Ma & Brian D. Brown & Miriam Merad - 1223-1231 Peroxisomal metabolism of branched fatty acids regulates energy homeostasis
by Xuejing Liu & Anyuan He & Dongliang Lu & Donghua Hu & Min Tan & Abenezer Abere & Parniyan Goodarzi & Bilal Ahmad & Brian Kleiboeker & Brian N. Finck & Mohamed Zayed & Katsuhiko Funai & Jonathan R. Brestoff & Ali Javaheri & Patricia Weisensee & Bettina Mittendorfer & Fong-Fu Hsu & Paul P. Veldhoven & Babak Razani & Clay F. Semenkovich & Irfan J. Lodhi - 1232-1242 Neuronal activity-dependent mechanisms of small cell lung cancer pathogenesis
by Solomiia Savchuk & Kaylee M. Gentry & Wengang Wang & Elana Carleton & Carlos A. O. Biagi-Junior & Karan Luthria & Belgin Yalçın & Lijun Ni & Hannah C. Farnsworth & Rachel A. Davis & Richard Drexler & Johannes C. Melms & Yin Liu & Lehi Acosta-Alvarez & Griffin G. Hartmann & Elisa C. Pavarino & Jenna LaBelle & Pamelyn J. Woo & Angus M. Toland & Fangfei Qu & Yoon Seok Kim & Mariella G. Filbin & Mark A. Krasnow & Keith L. Ligon & Benjamin Izar & Julien Sage & Bernardo L. Sabatini & Michelle Monje & Humsa S. Venkatesh - 1243-1253 Functional synapses between neurons and small cell lung cancer
by Vignesh Sakthivelu & Anna Schmitt & Franka Odenthal & Kristiano Ndoci & Marian Touet & Ali H. Shaib & Abdulla Chihab & Gulzar A. Wani & Pascal Nieper & Griffin G. Hartmann & Isabel Pintelon & Ilmars Kisis & Maike Boecker & Naja M. Eckert & Manoela Iannicelli Caiaffa & Olta Ibruli & Julia Weber & Roman Maresch & Christina M. Bebber & Ali Chitsaz & Anna Lütz & Mira Kim Alves Carpinteiro & Kaylee M. Morris & Camilla A. Franchino & Jonas Benz & Laura Pérez-Revuelta & Jorge A. Soriano-Campos & Maxim A. Huetzen & Jonas Goergens & Milica Jevtic & Hannah M. Jahn-Kelleter & Hans Zempel & Aleksandra Placzek & Alexandru A. Hennrich & Karl-Klaus Conzelmann & Hannah L. Tumbrink & Pascal Hunold & Joerg Isensee & Lisa Werr & Felix Gaedke & Astrid Schauss & Marielle Minère & Marie Müller & Henning Fenselau & Yin Liu & Alena Heimsoeth & Gülce S. Gülcüler Balta & Henning Walczak & Christian Frezza & Ron D. Jachimowicz & Julie George & Marcel Schmiel & Johannes Brägelmann & Tim Hucho & Silvia Karstedt & Martin Peifer & Alessandro Annibaldi & Robert Hänsel-Hertsch & Thorsten Persigehl & Holger Grüll & Martin L. Sos & Guido Reifenberger & Matthias Fischer & Dirk Adriaensen & Reinhard Büttner & Julien Sage & Inge Brouns & Roland Rad & Roman K. Thomas & Max Anstötz & Silvio O. Rizzoli & Matteo Bergami & Elisa Motori & Hans Christian Reinhardt & Filippo Beleggia - 1254-1260 Engineered prime editors with minimal genomic errors
by Vikash P. Chauhan & Phillip A. Sharp & Robert Langer - 1261-1271 Spatial joint profiling of DNA methylome and transcriptome in tissues
by Chin Nien Lee & Hongxiang Fu & Angelysia Cardilla & Wanding Zhou & Yanxiang Deng - 1272-1280 Structure and mechanism of the mitochondrial calcium transporter NCLX
by Minrui Fan & Chen-Wei Tsai & Jinru Zhang & Jianxiu Zhang & Aswini R. Krishnan & Tsung-Yun Liu & Yu-Lun Huang & Deniz Aydin & Siyuan Du & Briana L. Sobecks & Madison X. Rodriguez & Andrew H. Reiter & Carolyn R. Bertozzi & Ron O. Dror & Ming-Feng Tsai & Liang Feng - 1281-1282 Cake to the rescue: how these PhD students are cooking up a sense of community
by Sarah Wells - 1284-1284 Preserving Pompeii’s past, one step at a time
by Agnese Abrusci
October 2025, Volume 646, Issue 8086
- 4-9 Uncertain climate effects of anthropogenic reactive nitrogen
by Øivind Hodnebrog & Caroline Jouan & Didier A. Hauglustaine & Fabien Paulot & Susanne E. Bauer & Maureen Beaudor & Michael J. Prather & Marit Sandstad & Ragnhild B. Skeie & Gunnar Myhre - 10-12 Reply to: Uncertain climate effects of anthropogenic reactive nitrogen
by Cheng Gong & Hanqin Tian & Hong Liao & Naiqing Pan & Shufen Pan & Akihiko Ito & Atul K. Jain & Sian Kou-Giesbrecht & Fortunat Joos & Qing Sun & Hao Shi & Nicolas Vuichard & Qing Zhu & Changhui Peng & Federico Maggi & Fiona H. M. Tang & Sönke Zaehle - 13-13 Author Correction: Clonal dynamics and somatic evolution of haematopoiesis in mouse
by Chiraag D. Kapadia & Nicholas Williams & Kevin J. Dawson & Caroline Watson & Matthew J. Yousefzadeh & Duy Le & Kudzai Nyamondo & Sreeya Kodavali & Alex Cagan & Sarah Waldvogel & Xiaoyan Zhang & Josephine Fuente & Daniel Leongamornlert & Emily Mitchell & Marcus A. Florez & Krzysztof Sosnowski & Rogelio Aguilar & Alejandra Martell & Anna Guzman & David Harrison & Laura J. Niedernhofer & Katherine Y. King & Peter J. Campbell & Jamie Blundell & Margaret A. Goodell & Jyoti Nangalia - 14-14 Author Correction: Mechanism of BRCA1–BARD1 function in DNA end resection and DNA protection
by Ilaria Ceppi & Maria Rosaria Dello Stritto & Martin Mütze & Stefan Braunshier & Valentina Mengoli & Giordano Reginato & Hồ Mỹ Phúc Võ & Sonia Jimeno & Ananya Acharya & Megha Roy & Aurore Sanchez & Swagata Halder & Sean Michael Howard & Raphaël Guérois & Pablo Huertas & Sylvie M. Noordermeer & Ralf Seidel & Petr Cejka - 15-15 Author Correction: Selenium-alloyed tellurium oxide for amorphous p-channel transistors
by Ao Liu & Yong-Sung Kim & Min Gyu Kim & Youjin Reo & Taoyu Zou & Taesu Choi & Sai Bai & Huihui Zhu & Yong-Young Noh - 16-16 Publisher Correction: Multimodal cell maps as a foundation for structural and functional genomics
by Leah V. Schaffer & Mengzhou Hu & Gege Qian & Kyung-Mee Moon & Abantika Pal & Neelesh Soni & Andrew P. Latham & Laura Pontano Vaites & Dorothy Tsai & Nicole M. Mattson & Katherine Licon & Robin Bachelder & Anthony Cesnik & Ishan Gaur & Trang Le & William Leineweber & Aji Palar & Ernst Pulido & Yue Qin & Xiaoyu Zhao & Christopher Churas & Joanna Lenkiewicz & Jing Chen & Keiichiro Ono & Dexter Pratt & Peter Zage & Ignacia Echeverria & Andrej Sali & J. Wade Harper & Steven P. Gygi & Leonard J. Foster & Edward L. Huttlin & Emma Lundberg & Trey Ideker - 17-17 Publisher Correction: Functional synapses between neurons and small cell lung cancer
by Vignesh Sakthivelu & Anna Schmitt & Franka Odenthal & Kristiano Ndoci & Marian Touet & Ali H. Shaib & Abdulla Chihab & Gulzar A. Wani & Pascal Nieper & Griffin G. Hartmann & Isabel Pintelon & Ilmars Kisis & Maike Boecker & Naja M. Eckert & Manoela Iannicelli Caiaffa & Olta Ibruli & Julia Weber & Roman Maresch & Christina M. Bebber & Ali Chitsaz & Anna Lütz & Mira Kim Alves Carpinteiro & Kaylee M. Morris & Camilla A. Franchino & Jonas Benz & Laura Pérez-Revuelta & Jorge A. Soriano-Campos & Maxim A. Huetzen & Jonas Goergens & Milica Jevtic & Hannah M. Jahn-Kelleter & Hans Zempel & Aleksandra Placzek & Alexandru A. Hennrich & Karl-Klaus Conzelmann & Hannah L. Tumbrink & Pascal Hunold & Joerg Isensee & Lisa Werr & Felix Gaedke & Astrid Schauss & Marielle Minère & Marie Müller & Henning Fenselau & Yin Liu & Alena Heimsoeth & Gülce S. Gülcüler Balta & Henning Walczak & Christian Frezza & Ron D. Jachimowicz & Julie George & Marcel Schmiel & Johannes Brägelmann & Tim Hucho & Silvia Karstedt & Martin Peifer & Alessandro Annibaldi & Robert Hänsel-Hertsch & Thorsten Persigehl & Holger Grüll & Martin L. Sos & Guido Reifenberger & Matthias Fischer & Dirk Adriaensen & Reinhard Büttner & Julien Sage & Inge Brouns & Roland Rad & Roman K. Thomas & Max Anstötz & Silvio O. Rizzoli & Matteo Bergami & Elisa Motori & Hans Christian Reinhardt & Filippo Beleggia - 23-23 We need more than good science to fight infectious disease
by Bec Crew - 24-27 Measles, polio, tuberculosis: what’s causing spikes in infectious diseases?
by Rachel Nuwer - 30-32 Four game-changing immunology tools to watch
by Gemma Conroy - 777-777 The TrumpRx website won’t slash drug prices — but this will
by Beth Woods - 779-780 Mysterious cosmic ‘dots’ are baffling astronomers. What are they?
by Jenna Ahart - 780-781 Global health is in crisis — who will step in to fix it?
by Fred Schwaller - 782-783 Economics Nobel prize won by researchers who showed how science boosts growth
by Philip Ball - 783-783 First proposed blood test for chronic fatigue syndrome: what scientists think
by David Adam - 784-785 More than 30% of this century’s science Nobel prizewinners immigrated: see their journeys
by Jenna Ahart - 786-786 AI bots wrote and reviewed all papers at this conference
by Elizabeth Gibney - 788-791 Universities are embracing AI: will students get smarter or stop thinking?
by Helen Pearson - 792-794 How to spot fake scientists and stop them from publishing papers
by Miryam Naddaf - 795-796 Why we still don’t understand the Universe — even after a century of dispute
by Helge Kragh - 797-797 Mark Norell obituary: palaeontologist who showed that dinosaurs still walk among us — as birds
by Michael J. Novacek - 799-801 Alternatives to animal testing are the future — it’s time that journals, funders and scientists embrace them
by Todd J. Herron & Anke Brüning-Richardson & Julie E. Gough & Aline F. Miller & Geoffrey J. Pilkington & John Greenman & Valerie Speirs & Joseph C. Wu - 802-803 Why simply ending animal testing isn’t the answer in biomedical research
by K. C. Kent Lloyd - 804-804 Genetics can give evolving societies a leg up
by Andrew J. Doig - 804-804 Take the time to ensure that AI is safe
by Sam Illingworth - 804-804 The race for deep-sea minerals could cause geopolitical and ecological harm
by Milad Haghani & Abbas Rajabifard & Thomas Wiedmann & David A. Hensher - 804-804 Brazil must beef up its COP30 scheme to preserve tropical forests
by James D. Langston & Daniel S. Mendham & Ali Yansyah Abdurrahim & Jatna Supriatna - 805-806 Clues to why the weight-loss condition cachexia arises when cancer occurs
by Kerstin Haase & Mariam Jamal-Hanjani - 806-807 Copper-free chips generate robust ‘combs’ of multicoloured light
by Mher Ghulinyan & Martino Bernard - 808-809 Boosting immune cells to combat cancer using CRISPR engineering and large-scale in vivo testing
by Michael Hudecek - 809-811 Is there a ‘smoking gun’ test for quantum gravity?
by Zachary Weller-Davies - 811-812 How a tick-borne virus enters human cells
by Yaw Shin Ooi - 813-817 Classical theories of gravity produce entanglement
by Joseph Aziz & Richard Howl - 818-824 Joint neutrino oscillation analysis from the T2K and NOvA experiments
by The NOvA Collaboration & The T2K Collaboration - 825-830 Observation of constructive interference at the edge of quantum ergodicity
by Google Quantum AI and Collaborators - 831-836 Optimization by decoded quantum interferometry
by Stephen P. Jordan & Noah Shutty & Mary Wootters & Adam Zalcman & Alexander Schmidhuber & Robbie King & Sergei V. Isakov & Tanuj Khattar & Ryan Babbush - 837-842 A metallic p-wave magnet with commensurate spin helix
by Rinsuke Yamada & Max T. Birch & Priya R. Baral & Shun Okumura & Ryota Nakano & Shang Gao & Motohiko Ezawa & Takuya Nomoto & Jan Masell & Yuki Ishihara & Kamil K. Kolincio & Ilya Belopolski & Hajime Sagayama & Hironori Nakao & Kazuki Ohishi & Takashi Ohhara & Ryoji Kiyanagi & Taro Nakajima & Yoshinori Tokura & Taka-hisa Arima & Yukitoshi Motome & Moritz M. Hirschmann & Max Hirschberger - 843-849 Deterministic soliton microcombs in Cu-free photonic integrated circuits
by Xinru Ji & Xurong Li & Zheru Qiu & Rui Ning Wang & Marta Divall & Andrey Gelash & Grigory Lihachev & Tobias J. Kippenberg - 850-855 Cryogenic X-ray photoelectron spectroscopy for battery interfaces
by Sanzeeda Baig Shuchi & Giulio D’Acunto & Philaphon Sayavong & Solomon T. Oyakhire & Kenzie M. Sanroman Gutierrez & Juliet Risner-Jamtgaard & Il Rok Choi & Yi Cui & Stacey F. Bent - 856-864 Modern sea-level rise breaks 4,000-year stability in southeastern China
by Yucheng Lin & Robert E. Kopp & Haixian Xiong & Fiona D. Hibbert & Zhuo Zheng & Fengling Yu & Praveen Kumar & Sönke Dangendorf & Hailin Yi & Yaze Zhang - 865-871 In situ light-field imaging of octopus locomotion reveals simplified control
by Kakani Katija & Christine L. Huffard & Paul L. D. Roberts & Joost Daniels & Jon Erickson & Denis Klimov & Henry A. Ruhl & Alana D. Sherman - 872-882 A compressed hierarchy for visual form processing in the tree shrew
by Frank F. Lanfranchi & Joseph Wekselblatt & Daniel A. Wagenaar & Doris Y. Tsao - 883-892 Rate and noise in human amygdala drive increased exploration in aversive learning
by Tamar Reitich-Stolero & Kristoffer C. Aberg & Dean Halperin & Carmel Ariel & Genela Morris & Lilach Goldstein & Firas Fahoum & Ido Strauss & Rony Paz - 893-902 Human gastroids to model regional patterning in early stomach development
by Xia Li & Feng Lin & Qiqi Cui & Shiyu Sun & Shixin Li & Yue Wang & Yiting Wang & Jianbo Bai & Shiyi Liu & Jia Guo & Yizhao Han & Meiru Zhang & Tie Chang & Yifan Zheng & Jianlin Liu & Longqi Liu & Leyun Wang & Jianping Fu & Xin Liu & Bing Bai & Yue Shao - 903-912 Therapeutic genetic restoration through allogeneic brain microglia replacement
by Marius Marc-Daniel Mader & Alexa Scavetti & Yongjin Yoo & Aaron Tianyue Chai & Takeshi Uenaka & Marius Wernig - 913-924 Microglia–neuron crosstalk through Hex–GM2–MGL2 maintains brain homeostasis
by Maximilian Frosch & Takashi Shimizu & Emile Wogram & Lukas Amann & Lars Gruber & Ayelén I. Groisman & Maximilian Fliegauf & Marius Schwabenland & Chintan Chhatbar & Sabrina Zechel & Hendrik Rosewich & Jutta Gärtner & Francisco J. Quintana & Joerg M. Buescher & Thomas Blank & Harald Binder & Christine Stadelmann & Johannes J. Letzkus & Carsten Hopf & Takahiro Masuda & Klaus-Peter Knobeloch & Marco Prinz - 925-933 Microbial iron oxide respiration coupled to sulfide oxidation
by Song-Can Chen & Xiao-Min Li & Nicola Battisti & Guoqing Guan & Maria A. Montoya & Jay Osvatic & Petra Pjevac & Shaul Pollak & Andreas Richter & Arno Schintlmeister & Wolfgang Wanek & Marc Mussmann & Alexander Loy - 934-944 Dynamic fibroblast–immune interactions shape recovery after brain injury
by Nathan A. Ewing-Crystal & Nicholas M. Mroz & Amara Larpthaveesarp & Carlos O. Lizama & Remy Pennington & Pailin Chiaranunt & Jason I. Dennis & Anthony A. Chang & Eric Dean Merrill & Sofia E. Caryotakis & Nikhita Kirthivasan & Leon Teo & Tatsuya Tsukui & Aditya Katewa & Gabriel L. McKinsey & Sophia C. K. Nelson & Agnieszka Ciesielska & Nicole C. Lummis & Lucija Pintarić & Madelene W. Dahlgren & Amha Atakilit & Helena Paidassi & Saket Jain & Xiaodan Liu & Duan Xu & Manish K. Aghi & James A. Bourne & Jeanne T. Paz & Richard Daneman & Fernando F. Gonzalez & Dean Sheppard & Anna V. Molofsky & Thomas D. Arnold & Ari B. Molofsky - 945-952 LRP8 is a receptor for tick-borne encephalitis virus
by Eva Mittler & Alexandra L. Tse & Pham-Tue-Hung Tran & Catalina Florez & Javier Janer & Renata Varnaite & Ezgi Kasikci & Vasantha Kumar MV & Michaela Loomis & Wanda Christ & Erik Cazares & Russell R. Bakken & Caroline K. Martin & Xiankun Zeng & Jo Lynne Raymond & Mansoureh Shahsavani & Sara Khanal & Eric R. Wilkinson & Rischa Maya Oktavia & Megan M. Slough & Denise Haslwanter & Julianna Han & Jacob Berrigan & Ebba Rosendal & Margaret Kielian & Balaji Manicassamy & Anna K. Överby & Anna Falk & Giovanna Barba-Spaeth & Felix A. Rey & Jonas Klingström & Evripidis Gavathiotis & Andrew S. Herbert & Kartik Chandran & Sara Gredmark-Russ - 953-962 In vivo CRISPR screens identify modifiers of CAR T cell function in myeloma
by Nelson H. Knudsen & Giulia Escobar & Felix Korell & Tamina Kienka & Celeste Nobrega & Seth Anderson & Andrew Y. Cheng & Maria Zschummel & Alexander Armstrong & Amanda Bouffard & Michael C. Kann & Sadie Goncalves & Hans W. Pope & Mitra Pezeshki & Alexander Rojas & Juliette S. M. T. Suermondt & Merle Phillips & Trisha R. Berger & Sangwoo Park & Diego Salas-Benito & Elijah P. Darnell & Filippo Birocchi & Mark B. Leick & Rebecca C. Larson & John G. Doench & Debattama Sen & Kathleen B. Yates & Robert T. Manguso & Marcela V. Maus - 963-972 Systematic discovery of CRISPR-boosted CAR T cell immunotherapies
by Paul Datlinger & Eugenia V. Pankevich & Cosmas D. Arnold & Nicole Pranckevicius & Jenny Lin & Daria Romanovskaia & Moritz Schaefer & Francesco Piras & Anne-Christine Orts & Amelie Nemc & Paulina N. Biesaga & Michelle Chan & Teresa Neuwirth & Artem V. Artemov & Wentao Li & Sabrina Ladstätter & Thomas Krausgruber & Christoph Bock - 973-982 Molecular subtypes of human skeletal muscle in cancer cachexia
by Bhumi J. Bhatt & Sunita Ghosh & Vera Mazurak & Aurélien Q. Brun & Oliver Bathe & Vickie E. Baracos & Sambasivarao Damaraju - 983-991 CRISPR activation for SCN2A-related neurodevelopmental disorders
by Serena Tamura & Andrew D. Nelson & Perry W. E. Spratt & Elizabeth C. Hamada & Xujia Zhou & Henry Kyoung & Zizheng Li & Coline Arnould & Vladyslav Barskyi & Beniamin Krupkin & Kiana Young & Jingjing Zhao & Stephanie S. Holden & Atehsa Sahagun & Caroline M. Keeshen & Congyi Lu & Roy Ben-Shalom & Sunrae E. Taloma & Selin Schamiloglu & Ying C. Li & Lia Min & Paul M. Jenkins & Jen Q. Pan & Jeanne T. Paz & Stephan J. Sanders & Navneet Matharu & Nadav Ahituv & Kevin J. Bender - 992-1000 DNA2 enables growth by restricting recombination-restarted replication
by Jessica J. R. Hudson & Rowin Appanah & David Jones & Kathryn Davidson & Alice M. Budden & Alina Vaitsiankova & Kok-Lung Chan & Keith W. Caldecott & Antony M. Carr & Ulrich Rass - 1001-1011 Multiple overlapping binding sites determine transcription factor occupancy
by Shubham Khetan & Brent S. Carroll & Martha L. Bulyk - 1013-1016 Are these the happiest PhD students in the world?
by Linda Nordling - 1018-1018 Cold plunge: how I gained hands-on experience in marine biology
by Nikki Forrester
October 2025, Volume 646, Issue 8085
- 517-517 How journals can break down barriers for Latin American scientists
by Mariana Viglino - 518-518 Inside our university’s mission to pivot to research
by Doreen Ramogola-Masire - 521-522 Medicine Nobel goes to scientists who revealed secrets of immune system ‘regulation’
by Miryam Naddaf & Elizabeth Gibney - 522-523 Chemistry Nobel for scientists who developed massively porous ‘super sponge’ materials
by Davide Castelvecchi & Miryam Naddaf - 523-524 Groundbreaking quantum-tunnelling experiments win physics Nobel
by Elizabeth Gibney & Davide Castelvecchi - 524-525 Creative hobbies could slow brain ageing at the molecular level
by Gemma Conroy - 525-525 First human transplant of kidney modified to have ‘universal’ blood type
by Rachel Fieldhouse - 526-527 The rise of ‘nightmare bacteria’: antimicrobial resistance in five charts
by Katie Kavanagh - 528-528 ‘Google for DNA’ brings order to biology’s big data
by Elie Dolgin - 530-532 Faulty mitochondria cause deadly diseases: fixing them is about to get a lot easier
by Gemma Conroy - 534-536 The quest to make babies with lab-grown eggs and sperm
by Heidi Ledford - 537-538 Alchemy: discredited pseudoscience or chemistry’s worthy ancestor?
by Kit Chapman - 539-540 The race to uncover snow’s many mysteries before it disappears forever
by Gareth Thompson - 541-541 Jane Goodall obituary: pioneer primatologist who inspired generations of scientists
by Richard Wrangham - 543-546 Carbon credits are failing to help with climate change — here’s why
by Andrew Macintosh & Gregory Trencher & Benedict Probst & Shanta Barley & Danny Cullenward & Thales A. P. West & Don Butler & Johan Rockström - 547-549 Metals are key to the global economy — but three challenges threaten supply chains
by Tarasankar DebRoy & Todd A. Palmer & John W. Elmer & Tuhin Mukherjee - 550-550 AI’s therapeutic potential goes beyond emotional connection
by Elad Refoua & Eshkol Rafaeli & Dorit Hadar Shoval - 550-550 Brazil’s COP30 legacy should be to protect more of its forests
by Paulo Moutinho & André Guimarães - 550-550 Longer grant cycles would boost research in Africa
by Fulufhelo Nemavhola - 550-550 Red lines for religious AI
by Max Tretter & Anna Puzio - 551-552 Ion stencils used for synthesis of patchy nanoparticles
by Ilona Kretzschmar & Emanuela Bianchi - 552-554 Flies evolved a shock-absorber tissue used during embryonic development
by Thibaut Brunet - 554-554 Birds’ intruder alert hints at how sounds took on new meanings
by Holly Smith - 555-556 Extreme confinement unleashes water’s hidden electrical capabilities
by Neus Domingo & Albert Verdaguer - 556-558 Caribbean coral reefs are threatened by rising seas
by Nicola K. Browne - 558-559 A drug–diet combination could improve childhood cancer treatment
by Frank Speleman & Louis Delhaye - 561-566 Efficient quantum thermal simulation
by Chi-Fang Chen & Michael Kastoryano & Fernando G. S. L. Brandão & András Gilyén - 567-575 Integrated lithium niobate photonics for sub-ångström snapshot spectroscopy
by Zhiyang Yao & Shuyang Liu & Yingce Wang & Xiaoyun Yuan & Lu Fang - 576-583 Proximal cooperative aerial manipulation with vertically stacked drones
by Huazi Cao & Jiahao Shen & Yin Zhang & Zheng Fu & Cunjia Liu & Sihao Sun & Shiyu Zhao - 584-591 Long-distance remote epitaxy
by Ru Jia & Yan Xin & Mark Potter & Jie Jiang & Zixu Wang & Hanxue Ma & Zhihao Zhang & Zhizhuo Liang & Lifu Zhang & Zonghuan Lu & Ruizhe Yang & Saloni Pendse & Yang Hu & Kai Peng & Yilin Meng & Wei Bao & Jun Liu & Gwo-Ching Wang & Toh-Ming Lu & Yunfeng Shi & Hanwei Gao & Jian Shi - 592-600 Patchy nanoparticles by atomic stencilling
by Ahyoung Kim & Chansong Kim & Tommy Waltmann & Thi Vo & Eun Mi Kim & Junseok Kim & Yu-Tsun Shao & Aaron Michelson & John R. Crockett & Falon C. Kalutantirige & Eric Yang & Lehan Yao & Chu-Yun Hwang & Yugang Zhang & Yu-Shen Liu & Hyosung An & Zirui Gao & Jiyeon Kim & Sohini Mandal & David A. Muller & Kristen A. Fichthorn & Sharon C. Glotzer & Qian Chen - 601-605 Marcus kinetics control singlet and triplet oxygen evolving from superoxide
by Soumyadip Mondal & Huyen T. K. Nguyen & Robert Hauschild & Stefan A. Freunberger - 606-610 In-plane dielectric constant and conductivity of confined water
by R. Wang & M. Souilamas & A. Esfandiar & R. Fabregas & S. Benaglia & H. Nevison-Andrews & Q. Yang & J. Normansell & P. Ares & G. Ferrari & A. Principi & A. K. Geim & L. Fumagalli - 611-618 Aboveground biomass in Australian tropical forests now a net carbon source
by Hannah Carle & David Bauman & Michael N. Evans & Ingrid Coughlin & Oliver Binks & Andrew Ford & Matthew Bradford & Adrienne Nicotra & Helen Murphy & Patrick Meir - 619-626 Reduced Atlantic reef growth past 2 °C warming amplifies sea-level impacts
by Chris T. Perry & Didier M. Bakker & Alice E. Webb & Steeve Comeau & Ben P. Harvey & Christopher E. Cornwall & Lorenzo Alvarez-Filip & Esmeralda Pérez-Cervantes & John Morris & Ian C. Enochs & Lauren T. Toth & Aaron O’Dea & Erin M. Dillon & Erik H. Meesters & William F. Precht - 627-636 Patterned invagination prevents mechanical instability during gastrulation
by Bruno C. Vellutini & Marina B. Cuenca & Abhijeet Krishna & Alicja Szałapak & Carl D. Modes & Pavel Tomancak - 637-646 Divergent evolutionary strategies pre-empt tissue collision in gastrulation
by Bipasha Dey & Verena Kaul & Girish Kale & Maily Scorcelletti & Michiko Takeda & Yu-Chiun Wang & Steffen Lemke - 647-656 Parent-of-origin effects on complex traits in up to 236,781 individuals
by Robin J. Hofmeister & Théo Cavinato & Roya Karimi & Adriaan Graaf & Fanny-Dhelia Pajuste & Jaanika Kronberg & Nele Taba & Reedik Mägi & Marc Vaudel & Simone Rubinacci & Stefan Johansson & Lili Milani & Olivier Delaneau & Zoltán Kutalik - 657-666 Single-cell transcriptomic and genomic changes in the ageing human brain
by Ailsa M. Jeffries & Tianxiong Yu & Jennifer S. Ziegenfuss & Allie K. Tolles & Christina E. Baer & Cesar Bautista Sotelo & Yerin Kim & Zhiping Weng & Michael A. Lodato - 667-675 Network synchrony creates neural filters promoting quiescence in Drosophila
by Davide Raccuglia & Raquel Suárez-Grimalt & Laura Krumm & Anatoli Ender & Cédric B. Brodersen & Sridhar R. Jagannathan & Martin Freire Krück & Niccolò P. Pampaloni & Carolin Rauch & York Winter & Genevieve Yvon-Durocher & Richard Kempter & Jörg R. P. Geiger & David Owald - 676-686 Microglia regulate GABAergic neurogenesis in prenatal human brain through IGF1
by Diankun Yu & Samhita Jain & Andi Wangzhou & Beika Zhu & Wenyuan Shao & Elena J. Coley-O’Rourke & Stacy Florencio & JaeYeon Kim & Jennifer Ja-Yoon Choi & Mercedes F. Paredes & Tomasz J. Nowakowski & Eric J. Huang & Xianhua Piao - 687-696 Haematopoietic stem cell number is not solely defined by niche availability
by Shoichiro Takeishi & Tony Marchand & Wade R. Koba & Daniel K. Borger & Chunliang Xu & Chandan Guha & Aviv Bergman & Paul S. Frenette & Kira Gritsman & Ulrich Steidl - 697-706 Amygdala–liver signalling orchestrates glycaemic responses to stress
by J. R. E. Carty & K. Devarakonda & R. M. O’Connor & A. Krek & D. Espinoza & M. Jimenez-Gonzalez & A. Alvarsson & R. F. Hampton & R. Li & Y. Qiu & S. Petri & A. Shtekler & A. Rajbhandari & K. Conner & M. Bayne & D. Garibay & J. Martin & V. Lehmann & L. Wang & K. Beaumont & I. Kurland & G. C. Yuan & P. J. Kenny & S. A. Stanley - 707-715 Reprogramming neuroblastoma by diet-enhanced polyamine depletion
by Sarah Cherkaoui & Christina S. Turn & Yuan Yuan & Wenyun Lu & Lifeng Yang & Matthew J. McBride & Caroline Eigenmann & George E. Allen & Olesya O. Panasenko & Lu Zhang & Annette Vu & Kangning Liu & Yimei Li & Om H. Gandhi & Lea F. Surrey & Sandra D. Kienast & Sebastian A. Leidel & Michael Wierer & Eileen White & Joshua D. Rabinowitz & Michael D. Hogarty & Raphael J. Morscher - 716-723 The Virtual Lab of AI agents designs new SARS-CoV-2 nanobodies
by Kyle Swanson & Wesley Wu & Nash L. Bulaong & John E. Pak & James Zou - 724-733 Thymic epithelial cells amplify epigenetic noise to promote immune tolerance
by Noah Gamble & Jason A. Caldwell & Joshua McKeever & Caroline Kaiser & Alexandra Bradu & Peyton J. Dooley & Sandy Klemm & William J. Greenleaf & Narutoshi Hibino & Aaron R. Dinner & Andrew S. Koh - 734-745 Targeting G1–S-checkpoint-compromised cancers with cyclin A/B RxL inhibitors
by Shilpa Singh & Catherine E. Gleason & Min Fang & Yasmin N. Laimon & Vishal Khivansara & Shanhai Xie & Yavuz T. Durmaz & Aniruddha Sarkar & Kenneth Ngo & Varunika Savla & Yixiang Li & Muhannad Abu-Remaileh & Xinyue Li & Marie-Anais Locquet & Bishma Tuladhar & Ranya Odeh & Frances Hamkins-Indik & Daphne He & Miles W. Membreno & Meisam Nosrati & Nathan N. Gushwa & Siegfried S. F. Leung & Breena Fraga-Walton & Luis Hernandez & Miguel P. Baldomero & Bryan M. Lent & David Spellmeyer & Joshua F. Luna & Dalena Hoang & Yuliana Gritsenko & Manesh Chand & Megan K. DeMart & Sammy Metobo & Chinmay Bhatt & Justin A. Shapiro & Kai Yang & Nathan J. Dupper & Andrew T. Bockus & Jinshu Fang & Ramesh Bambal & Peadar Cremin & John G. Doench & James B. Aggen & Li-Fen Liu & Bernard Levin & Evelyn W. Wang & Iolanda Vendrell & Roman Fischer & Benedikt Kessler & Prafulla C. Gokhale & Sabina Signoretti & Alexander Spektor & Constantine Kreatsoulas & Marie Evangelista & Rajinder Singh & David J. Earp & Deepak Nijhawan & Pablo D. Garcia & Matthew G. Oser - 746-753 Cocaine chemogenetics blunts drug-seeking by synthetic physiology
by Juan L. Gomez & Christopher J. Magnus & Jordi Bonaventura & Oscar Solis & Fallon P. Curry & Marjorie R. Levinstein & Reece C. Budinich & Meghan L. Carlton & Emilya N. Ventriglia & Sherry Lam & Le Wang & Ingrid Schoenborn & William Dunne & Michael Michaelides & Scott M. Sternson - 754-758 Crystal structures of agonist-bound human cannabinoid receptor CB1
by Tian Hua & Kiran Vemuri & Spyros P. Nikas & Yiran Wu & Lu Qu & Mengchen Pu & Anisha Korde & Shan Jiang & Jo-Hao Ho & Gye Won Han & Kang Ding & Xuanxuan Li & Haiguang Liu & Michael A. Hanson & Suwen Zhao & Laura M. Bohn & Alexandros Makriyannis & Raymond C. Stevens & Zhi-Jie Liu - 759-762 Research assessment: a round-up for early-career researchers
by Holly Else - 763-765 Digital flocks, predators allow ecologists to simulate real-world animal behaviour
by Heather Richardson - 768-768 Defending Ohuira Bay, Mexico
by Rachael Pells
October 2025, Volume 646, Issue 8084
- 261-261 Prizes must recognize machine contributions to discovery
by Dashun Wang - 263-264 US serial killer case opens door to using cutting-edge DNA data in courts
by Katherine Bourzac - 264-266 NIH races to spend its 2025 grant money — but fewer projects win funding
by Max Kozlov - 266-267 China pledges to cut emissions by 2035: what does that mean for the climate?
by Xiaoying You - 267-268 Swapping old immune cells in the brain with fresh ones could treat disease
by Heidi Ledford - 268-269 Will your study change the world? This AI tool predicts the impact of your research
by Brian Owens - 269-270 Want to do disruptive science? Include more rookie researchers
by Katie Kavanagh - 270-270 See space fireworks and lightning spaghetti — September’s best science images
by Fred Schwaller & Katie Kavanagh - 272-275 AI models that lie, cheat and plot murder: how dangerous are LLMs really?
by Matthew Hutson - 276-278 Will AI ever win its own Nobel? Some predict a prize-worthy science discovery soon
by Jenna Ahart - 279-280 From fossil fuels to ‘green capitalism’: the dilemmas of a just energy transition
by Sophia Kalantzakos - 281-283 The cutting-edge medical approaches that could transform ageing
by Coleen T. Murphy - 283-283 Violin therapy: Books in brief
by Andrew Robinson - 284-286 Stop treating code like an afterthought: record, share and value it
by Roberto Di Cosmo & Sabrina Granger & Konrad Hinsen & Nicolas Jullien & Daniel Le Berre & Violaine Louvet & Camille Maumet & Clémentine Maurice & Raphaël Monat & Nicolas P. Rougier - 286-287 Customizable AI systems that anyone can adapt bring big opportunities — and even bigger risks
by Yarin Gal & Stephen Casper - 288-288 Microbe discovery holds promise for sustainable biotechnology
by Jie Li & Shuwen Liu & Hao Song & Shiming Ding - 288-288 Insect biodiversity monitoring must be expanded
by Kris A. G. Wyckhuys & Yves Basset & Owen T. Lewis - 288-288 Incentives accelerate progress on open access in Spain
by Wenceslao Arroyo-Machado & Daniel Torres-Salinas - 288-288 Stop destructive fishing in marine protected areas
by Jenna Sullivan-Stack & Estradivari & Elizabeth P. Pike & Fabrice Stephenson - 289-290 Ant queens produce sons of two distinct species
by Jessica Purcell - 290-291 Protests are infectious: mapping rural unrest in Revolutionary France
by Jack A. Goldstone - 292-293 Depriving brain tumours of an amino acid could enhance chemotherapy
by Daniel Mobilio & Sheila Singh - 293-295 Sacrificial metal speeds up synthesis of nano-alloys from multiple elements
by Yunqing Kang & Yusuke Yamauchi - 295-296 Ancient DNA clarifies the early history of the Slavs
by Steffen Patzold - 297-302 Southward impact excavated magma ocean at the lunar South Pole–Aitken basin
by Jeffrey C. Andrews-Hanna & William F. Bottke & Adrien Broquet & Alexander J. Evans & Gabriel Gowman & Brandon C. Johnson & James T. Keane & Janette N. Levin & Ananya Mallik & Simone Marchi & Samantha A. Moruzzi & Arkadeep Roy & Shigeru Wakita - 303-308 Low-overhead transversal fault tolerance for universal quantum computation
by Hengyun Zhou & Chen Zhao & Madelyn Cain & Dolev Bluvstein & Nishad Maskara & Casey Duckering & Hong-Ye Hu & Sheng-Tao Wang & Aleksander Kubica & Mikhail D. Lukin - 309-314 Quantum-amplified global-phase spectroscopy on an optical clock transition
by Leon Zaporski & Qi Liu & Gustavo Velez & Matthew Radzihovsky & Zeyang Li & Simone Colombo & Edwin Pedrozo-Peñafiel & Vladan Vuletić - 315-322 Heat-rechargeable computation in DNA logic circuits and neural networks
by Tianqi Song & Lulu Qian - 323-330 Isothermal solidification for high-entropy alloy synthesis
by Qiubo Zhang & Max C. Gallant & Yi Chen & Zhigang Song & Yang Liu & Qi Zheng & Linfeng Chen & Karen. C. Bustillo & Yu Huang & Kristin A. Persson & Haimei Zheng - 331-337 A ductile chromium–molybdenum alloy resistant to high-temperature oxidation
by Frauke Hinrichs & Georg Winkens & Lena Katharina Kramer & Gabriely Falcão & Ewa M. Hahn & Daniel Schliephake & Michael Konrad Eusterholz & Sandipan Sen & Mathias Christian Galetz & Haruyuki Inui & Alexander Kauffmann & Martin Heilmaier - 338-342 A room temperature rechargeable all-solid-state hydride ion battery
by Jirong Cui & Ren Zou & Weijin Zhang & Hong Wen & Jingyao Liu & Shangshang Wang & Shukun Liu & Hetong Chen & Wei Liu & Xiaohua Ju & Weiwei Wang & Tao Gan & Jiong Li & Jianping Guo & Teng He & Hujun Cao & Ping Chen - 343-350 Tailoring polymer electrolyte solvation for 600 Wh kg−1 lithium batteries
by Xue-Yan Huang & Chen-Zi Zhao & Wei-Jin Kong & Nan Yao & Zong-Yao Shuang & Pan Xu & Shuo Sun & Yang Lu & Wen-Ze Huang & Jin-Liang Li & Liang Shen & Xiang Chen & Jia-Qi Huang & Lynden A. Archer & Qiang Zhang - 351-357 Scalable total synthesis of saxitoxin and related natural products
by Yinliang Guo & Yiheng Li & Sihan Chen & Yige Wu & Oscar Poll & Zhouyang Ren & Zhonglin Liu & Roman Vlkolinsky & Michal Bajo & Christopher K. Prier & Kai-Jiong Xiao & Benjamin F. Cravatt & Marisa Roberto & Phil S. Baran - 358-364 Epidemiology models explain rumour spreading during France’s Great Fear of 1789
by Stefano Zapperi & Constant Varlet-Bertrand & Cécile Bastidon & Caterina A. M. Porta & Antoine Parent - 365-371 Engineered yeast provides rare but essential pollen sterols for honeybees
by Elynor Moore & Raquel T. Sousa & Stella Felsinger & Jonathan A. Arnesen & Jane D. Dyekjær & Dudley I. Farman & Rui F. S. Gonçalves & Philip C. Stevenson & Irina Borodina & Geraldine A. Wright - 372-377 One mother for two species via obligate cross-species cloning in ants
by Y. Juvé & C. Lutrat & A. Ha & A. Weyna & E. Lauroua & A. C. Afonso Silva & C. Roux & E. Schifani & C. Galkowski & C. Lebas & R. Allio & I. Stoyanov & N. Galtier & B. C. Schlick-Steiner & F. M. Steiner & D. Baas & B. Kaufmann & J. Romiguier - 378-383 Hominins on Sulawesi during the Early Pleistocene
by Budianto Hakim & Unggul Prasetyo Wibowo & Gerrit D. Bergh & Dida Yurnaldi & Renaud Joannes-Boyau & Akin Duli & Suryatman & Ratno Sardi & Indah Asikin Nurani & Mika Rizki Puspaningrum & Irfan Mahmud & Afdalah Haris & Khairun Al Anshari & Andi Muhammad Saiful & P. Arman Bungaran & Shinatria Adhityatama & Putra Hudlinas Muhammad & Anwar Akib & Nani Somba & Fakhri & Basran Burhan & Zubair Mas’ud & Mark W. Moore & Yinika L. Perston & Wenjing Yu & Maxime Aubert & Adam Brumm - 384-393 Ancient DNA connects large-scale migration with the spread of Slavs
by Joscha Gretzinger & Felix Biermann & Hellen Mager & Benedict King & Denisa Zlámalová & Luca Traverso & Guido A. Gnecchi Ruscone & Sanni Peltola & Elina Salmela & Gunnar U. Neumann & Rita Radzeviciute & Pavlína Ingrová & Radosław Liwoch & Iwona Wronka & Radomir Jurić & Anna Hyrchała & Barbara Niezabitowska-Wiśniewska & Bartłomiej Bartecki & Beata Borowska & Tomasz Dzieńkowski & Marcin Wołoszyn & Michał Wojenka & Jarosław Wilczyński & Małgorzata Kot & Eric Müller & Jörg Orschiedt & Gunita Zariņa & Päivi Onkamo & Falko Daim & Arnold Muhl & Ralf Schwarz & Marek Majer & Michael McCormick & Jan Květina & Tivadar Vida & Patrick J. Geary & Jiří Macháček & Mario Šlaus & Harald Meller & Walter Pohl & Zuzana Hofmanová & Johannes Krause - 394-403 A circuit that integrates drive state and social contact to gate mating
by Lindsey D. Salay & Doris Y. Tsao & David J. Anderson - 404-412 SLC45A4 is a pain gene encoding a neuronal polyamine transporter
by Steven J. Middleton & Sigurbjörn Markússon & Mikael Åkerlund & Justin C. Deme & Mandy Tseng & Wenqianglong Li & Sana R. Zuberi & Gabriel Kuteyi & Peter Sarkies & Georgios Baskozos & Jimena Perez-Sanchez & Adham Farah & Harry L. Hébert & Sylvanus Toikumo & Zhanru Yu & Susan Maxwell & Yin Y. Dong & Benedikt M. Kessler & Henry R. Kranzler & John E. Linley & Blair H. Smith & Susan M. Lea & Joanne L. Parker & Valeriya Lyssenko & Simon Newstead & David L. Bennett - 413-422 Rewiring of cortical glucose metabolism fuels human brain cancer growth
by Andrew J. Scott & Anjali Mittal & Baharan Meghdadi & Alexandra O’Brien & Justine Bailleul & Palavalasa Sravya & Abhinav Achreja & Weihua Zhou & Jie Xu & Angelica Lin & Kari Wilder-Romans & Ningning Liang & Ayesha U. Kothari & Navyateja Korimerla & Donna M. Edwards & Zhe Wu & Jiane Feng & Sophia Su & Li Zhang & Peter Sajjakulnukit & Anthony C. Andren & Junyoung O. Park & Johanna Hoeve & Vijay Tarnal & Kimberly A. Redic & Nathan R. Qi & Joshua L. Fischer & Ethan Yang & Michael S. Regan & Sylwia A. Stopka & Gerard Baquer & Krithika Suresh & Jann N. Sarkaria & Theodore S. Lawrence & Sriram Venneti & Nathalie Y. R. Agar & Erina Vlashi & Costas A. Lyssiotis & Wajd N. Al-Holou & Deepak Nagrath & Daniel R. Wahl - 423-432 Discovery of a widespread chemical signalling pathway in the Bacteroidota
by Luis Linares-Otoya & Jaden D. Shirkey & Bhuwan Khatri Chhetri & Amira Mira & Abhishek Biswas & Samuel L. Neff & Maria V. Linares-Otoya & Ye Chen & Julio V. Campos-Florian & Mayar L. Ganoza-Yupanqui & Philip D. Jeffrey & Frederick M. Hughson & Mohamed S. Donia - 433-441 A nanobody specific to prefusion glycoprotein B neutralizes HSV-1 and HSV-2
by Benjamin Vollmer & Henriette Ebel & Renate Rees & Julia Nentwig & Thomas Mulvaney & Jürgen Schünemann & Jens Krull & Maya Topf & Dirk Görlich & Kay Grünewald - 442-451 TCF1 and LEF1 promote B-1a cell homeostasis and regulatory function
by Qian Shen & Hao Wang & Jonathan A. Roco & Xiangpeng Meng & Marita Bosticardo & Marie Hodges & Michael Battaglia & Zhi-Ping Feng & Benjamin James Talks & Jason Powell & Vijaya Baskar Mahalingam Shanmugiah & Julia Chu & Najib M. Rahman & Alguili Elsheikh & Probir Chakravarty & Amalie Grenov & Max Emmerich & Ottavia M. Delmonte & Alexandra F. Freeman & Michael D. Keller & Brahim Belaid & Ilenia Papa & James C. Lee & Pablo F. Cañete & Paula Gonzalez-Figueroa & Yaoyuan Zhang & Hai-Hui Xue & Samra Turajlic & Luigi D. Notarangelo & Muzlifah Haniffa & Lee Ann Garrett-Sinha & Helen M. Parry & Nikolaos I. Kanellakis & Carola G. Vinuesa - 452-461 Axonal injury is a targetable driver of glioblastoma progression
by Melanie Clements & Wenhao Tang & Zan Florjanic Baronik & Holly Simpson Ragdale & Roger Oria & Dimitrios Volteras & Ian J. White & Gordon Beattie & Imran Uddin & Tchern Lenn & Rachel Lindsay & Sara Castro Devesa & Saketh R. Karamched & Mark F. Lythgoe & Vahid Shahrezaei & Valerie M. Weaver & Ryoichi Sugisawa & Federico Roncaroli & Samuel Marguerat & Ciaran S. Hill & Simona Parrinello - 462-473 Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy
by Erez N. Baruch & Frederico O. Gleber-Netto & Priyadharsini Nagarajan & Xiayu Rao & Shamima Akhter & Tuany Eichwald & Tongxin Xie & Mohammad Balood & Adebayo Adewale & Shorook Naara & Hinduja N. Sathishkumar & Shajedul Islam & William McCarthy & Brandi J. Mattson & Renata Ferrarotto & Michael K. Wong & Michael A. Davies & Sonali Jindal & Sreyashi Basu & Karine Roversi & Amin Reza Nikpoor & Maryam Ahmadi & Ali Ahmadi & Catherine Harwood & Irene Leigh & Dennis Gong & Paulino Tallón de Lara & Derrick L. Tao & Tara M. Davidson & Nadim J. Ajami & Andrew Futreal & Kunal Rai & Veena Kochat & Micah Castillo & Preethi Gunaratne & Ryan P. Goepfert & Sharia D. Hernandez & Nikhil I. Khushalani & Jing Wang & Stephanie S. Watowich & George A. Calin & Michael R. Migden & Mona Yuan & Naijiang Liu & Yi Ye & William L. Hwang & Paola D. Vermeer & Nisha J. D’Silva & Yuri L. Bunimovich & Dan Yaniv & Jared K. Burks & Javier Gomez & Patrick M. Dougherty & Kenneth Y. Tsai & James P. Allison & Padmanee Sharma & Jennifer A. Wargo & Jeffrey N. Myers & Sebastien Talbot & Neil D. Gross & Moran Amit - 474-482 Quantitative imaging of lipid transport in mammalian cells
by Juan M. Iglesias-Artola & Kristin Böhlig & Kai Schuhmann & Katelyn C. Cook & H. Mathilda Lennartz & Milena Schuhmacher & Pavel Barahtjan & Cristina Jiménez López & Radek Šachl & Vannuruswamy Garikapati & Karina Pombo-Garcia & Annett Lohmann & Petra Riegerová & Martin Hof & Björn Drobot & Andrej Shevchenko & Alf Honigmann & André Nadler - 483-492 One-shot design of functional protein binders with BindCraft
by Martin Pacesa & Lennart Nickel & Christian Schellhaas & Joseph Schmidt & Ekaterina Pyatova & Lucas Kissling & Patrick Barendse & Jagrity Choudhury & Srajan Kapoor & Ana Alcaraz-Serna & Yehlin Cho & Kourosh H. Ghamary & Laura Vinué & Brahm J. Yachnin & Andrew M. Wollacott & Stephen Buckley & Adrie H. Westphal & Simon Lindhoud & Sandrine Georgeon & Casper A. Goverde & Georgios N. Hatzopoulos & Pierre Gönczy & Yannick D. Muller & Gerald Schwank & Daan C. Swarts & Alex J. Vecchio & Bernard L. Schneider & Sergey Ovchinnikov & Bruno E. Correia - 493-500 Structural basis for the dynamic regulation of mTORC1 by amino acids
by Max L. Valenstein & Maximilian Wranik & Pranav V. Lalgudi & Karen Y. Linde-Garelli & Yuri Choi & Raghu R. Chivukula & David M. Sabatini & Kacper B. Rogala - 501-502 27 things we wish we’d known when we started our PhDs
by Linda Nordling - 503-505 Biothreat hunters catch dangerous DNA before it gets made
by Matthew Hutson - 508-508 Connecting the dots: I trace the history of the East Kolkata Wetlands
by Nikki Forrester
October 2025, Volume 646, Issue 8083
- 1-1 Author Correction: A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome
by Aline C. Simon & Jin C. Zhou & Rajika L. Perera & Frederick Deursen & Cecile Evrin & Marina E. Ivanova & Mairi L. Kilkenny & Ludovic Renault & Svend Kjaer & Dijana Matak-Vinković & Karim Labib & Alessandro Costa & Luca Pellegrini - 1-1 Hospitals have long been key for research, now their influence is broadening
by Jack Leeming - 2-2 Publisher Correction: Experimental determination of partial charges with electron diffraction
by Soheil Mahmoudi & Tim Gruene & Christian Schröder & Khalil D. Ferjaoui & Erik Fröjdh & Aldo Mozzanica & Kiyofumi Takaba & Anatoliy Volkov & Julian Maisriml & Vladimir Paunović & Jeroen A. van Bokhoven & Bernhard K. Keppler - 2-5 China’s research hospitals push for prominence
by Brian Owens - 3-3 Publisher Correction: TCF1 and LEF1 promote B-1a cell homeostasis and regulatory function
by Qian Shen & Hao Wang & Jonathan A. Roco & Xiangpeng Meng & Marita Bosticardo & Marie Hodges & Michael Battaglia & Zhi-Ping Feng & Benjamin James Talks & Jason Powell & Vijaya Baskar Mahalingam Shanmugiah & Julia Chu & Najib M. Rahman & Alguili Elsheikh & Probir Chakravarty & Amalie Grenov & Max Emmerich & Ottavia M. Delmonte & Alexandra F. Freeman & Michael D. Keller & Brahim Belaid & Ilenia Papa & James C. Lee & Pablo F. Cañete & Paula Gonzalez-Figueroa & Yaoyuan Zhang & Hai-Hui Xue & Samra Turajlic & Luigi D. Notarangelo & Muzlifah Haniffa & Lee Ann Garrett-Sinha & Helen M. Parry & Nikolaos I. Kanellakis & Carola G. Vinuesa - 8-10 Uniting Africa’s longitudinal cohorts
by Anna McKie - 9-9 Trust in the sea-bed mining authority is fragile — here’s how to change that
by Carlos Garcia-Soto - 10-10 Six journal rejections and a major rethink: why I’m happy to admit to my research failures, and you should too
by Séverine Toussaert - 10-12 Fixing the imbalance in cancer rates between Black and white women
by Anna McKie - 12-14 HELIOS: a microcosm of Asian health with global reach
by Anna McKie - 13-14 Trump links autism and Tylenol: is there any truth to it?
by Helen Pearson & Heidi Ledford - 15-15 Huntington’s disease treated for first time using gene therapy
by Elie Dolgin - 16-16 World’s first AI-designed viruses a step towards AI-generated life
by Katie Kavanagh - 17-18 Tipsy bats and perfect pasta: Ig Nobels celebrate ‘improbable’ research
by Chris Simms - 18-19 Can AI chatbots trigger psychosis? What the science says
by Rachel Fieldhouse - 19-20 The Moon is rusting — thanks to ‘wind’ blown all the way from Earth
by Alexandra Witze - 20-20 She lived to 117: what her genes and lifestyle tell us about longevity
by Mariana Lenharo - 22-25 AI is dreaming up millions of new materials. Are they any good?
by Mark Peplow - 26-28 How to get the best night’s sleep: what the science says
by Lynne Peeples - 29-30 Power and profit drive what we eat: here’s why the food system needs a revolution
by Laura Kelly - 31-34 Public trust in science has declined since COVID — virologists need to unite around safety standards
by Melanie Ott & Olivier Schwartz & Alex Sigal - 34-37 Technology leaders should ‘pay back’ society to support the common good
by Abilio Almeida - 38-38 India and Pakistan share flood risks and must combine solutions
by Saheeb Ahmed Kayani - 38-38 Add a ‘speculation box’ to research papers
by Milad Malekzadeh - 38-38 AI tools could reduce the appeal of predatory journals
by Alessandro Maria Selvitella & Kathleen Lois Foster - 38-38 Make cities more walkable, in the real world and in virtual reality
by Mohammad Javad Koohsari & Andrew T. Kaczynski - 39-40 Childhood eczema linked to mother’s stress during pregnancy
by Abhay P. S. Rathore & Soman N. Abraham
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