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Genetic analyses of diverse populations improves discovery for complex traits
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- Minta Thomas & Yu-Ru Su & Elisabeth A. Rosenthal & Lori C. Sakoda & Stephanie L. Schmit & Maria N. Timofeeva & Zhishan Chen & Ceres Fernandez-Rozadilla & Philip J. Law & Neil Murphy & Robert Carreras-, 2023. "Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
- Alexandra Barry & Michelle T. McNulty & Xiaoyuan Jia & Yask Gupta & Hanna Debiec & Yang Luo & China Nagano & Tomoko Horinouchi & Seulgi Jung & Manuela Colucci & Dina F. Ahram & Adele Mitrotti & Aditi , 2023. "Multi-population genome-wide association study implicates immune and non-immune factors in pediatric steroid-sensitive nephrotic syndrome," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
- Zuyou Wu & Yang Yang & Caibo Ning & Jiali Li & Yimin Cai & Yanmin Li & Zilong Cao & Shuangshuang Tian & Jingyi Peng & Qianying Ma & Chunyi He & Shuting Xia & Jun Chen & Xiaoping Miao & Zhen Li & Ying , 2025. "Genetic architecture of bone marrow fat fraction implies its involvement in osteoporosis risk," Nature Communications, Nature, vol. 16(1), pages 1-17, December.
- Eugene Lin & Yu-Ting Yan & Mu-Hong Chen & Albert C. Yang & Po-Hsiu Kuo & Shih-Jen Tsai, 2025. "Gene clusters linked to insulin resistance identified in a genome-wide study of the Taiwan Biobank population," Nature Communications, Nature, vol. 16(1), pages 1-14, December.
- Isabelle Austin-Zimmerman & Daniel F. Levey & Olga Giannakopoulou & Joseph D. Deak & Marco Galimberti & Keyrun Adhikari & Hang Zhou & Spiros Denaxas & Haritz Irizar & Karoline Kuchenbaecker & Andrew M, 2023. "Genome-wide association studies and cross-population meta-analyses investigating short and long sleep duration," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
- Chien-Ling Lee & Jianxiu Zhang & Liang Feng, 2025. "Molecular mechanisms of thiazide-like diuretics-mediated inhibition of the human Na-Cl cotransporter," Nature Communications, Nature, vol. 16(1), pages 1-13, December.
- Longbo Yang & Wenchuang He & Yiwang Zhu & Yang Lv & Yilin Li & Qianqian Zhang & Yifan Liu & Zhiyuan Zhang & Tianyi Wang & Hua Wei & Xinglan Cao & Yan Cui & Bin Zhang & Wu Chen & Huiying He & Xianmeng , 2025. "GWAS meta-analysis using a graph-based pan-genome enhanced gene mining efficiency for agronomic traits in rice," Nature Communications, Nature, vol. 16(1), pages 1-9, December.
- Quan Sun & Bryce T. Rowland & Jiawen Chen & Anna V. Mikhaylova & Christy Avery & Ulrike Peters & Jessica Lundin & Tara Matise & Steve Buyske & Ran Tao & Rasika A. Mathias & Alexander P. Reiner & Paul , 2024. "Improving polygenic risk prediction in admixed populations by explicitly modeling ancestral-differential effects via GAUDI," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
- Jingning Zhang & Jianan Zhan & Jin Jin & Cheng Ma & Ruzhang Zhao & Jared O’Connell & Yunxuan Jiang & Bertram L. Koelsch & Haoyu Zhang & Nilanjan Chatterjee, 2024. "An ensemble penalized regression method for multi-ancestry polygenic risk prediction," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
- Wei Fu & Shin-Yi Chou & Li-San Wang, 2022. "NIH Grant Expansion, Ancestral Diversity and Scientific Discovery in Genomics Research," NBER Working Papers 30155, National Bureau of Economic Research, Inc.
- Katrina G. Claw & Casey R. Dorr & Erica L. Woodahl, 2024. "Implementing community-engaged pharmacogenomics in Indigenous communities," Nature Communications, Nature, vol. 15(1), pages 1-5, December.
- Raluca Petrican & Alex Fornito & Christopher Murgatroyd & Emma Boyland & Charlotte A. Hardman, 2025. "Genetic risk predicts adolescent mood pathology via sexual differentiation of brain function and physiological aging," Nature Communications, Nature, vol. 16(1), pages 1-21, December.
- Benjamin M. Jacobs & Daniel Stow & Sam Hodgson & Julia Zöllner & Miriam Samuel & Stavroula Kanoni & Saeed Bidi & Klaudia Walter & Claudia Langenberg & Ruth Dobson & Sarah Finer & Caroline Morton & Mon, 2024. "Genetic architecture of routinely acquired blood tests in a British South Asian cohort," Nature Communications, Nature, vol. 15(1), pages 1-12, December.
- Chen Wang & Tianying Wang & Krzysztof Kiryluk & Ying Wei & Hugues Aschard & Iuliana Ionita-Laza, 2024. "Genome-wide discovery for biomarkers using quantile regression at biobank scale," Nature Communications, Nature, vol. 15(1), pages 1-13, December.
- Dmitrii Usoltsev & Nikita Kolosov & Oxana Rotar & Alexander Loboda & Maria Boyarinova & Ekaterina Moguchaya & Ekaterina Kolesova & Anastasia Erina & Kristina Tolkunova & Valeriia Rezapova & Ivan Molot, 2024. "Complex trait susceptibilities and population diversity in a sample of 4,145 Russians," Nature Communications, Nature, vol. 15(1), pages 1-10, December.
- Ananyo Choudhury & Jean-Tristan Brandenburg & Tinashe Chikowore & Dhriti Sengupta & Palwende Romuald Boua & Nigel J. Crowther & Godfred Agongo & Gershim Asiki & F. Xavier Gómez-Olivé & Isaac Kisiangan, 2022. "Meta-analysis of sub-Saharan African studies provides insights into genetic architecture of lipid traits," Nature Communications, Nature, vol. 13(1), pages 1-13, December.
- Lauren E. Petty & Hung-Hsin Chen & Elizabeth G. Frankel & Wanying Zhu & Carolina G. Downie & Mariaelisa Graff & Phillip Lin & Priya Sharma & Xinruo Zhang & Alyssa C. Scartozzi & Rashedeh Roshani & Jos, 2025. "Large-scale multi-omics analyses in Hispanic/Latino populations identify genes for cardiometabolic traits," Nature Communications, Nature, vol. 16(1), pages 1-13, December.
- Xinyuan Zhang & Anastasia M. Lucas & Yogasudha Veturi & Theodore G. Drivas & William P. Bone & Anurag Verma & Wendy K. Chung & David Crosslin & Joshua C. Denny & Scott Hebbring & Gail P. Jarvik & Ifti, 2022. "Large-scale genomic analyses reveal insights into pleiotropy across circulatory system diseases and nervous system disorders," Nature Communications, Nature, vol. 13(1), pages 1-12, December.
- Leqi Xu & Geyu Zhou & Wei Jiang & Haoyu Zhang & Yikai Dong & Leying Guan & Hongyu Zhao, 2025. "JointPRS: A data-adaptive framework for multi-population genetic risk prediction incorporating genetic correlation," Nature Communications, Nature, vol. 16(1), pages 1-20, December.
- Javier G. Serrano & Alejandra C. Ordóñez & Jonathan Santana & Elías Sánchez-Cañadillas & Matilde Arnay & Amelia Rodríguez-Rodríguez & Jacob Morales & Javier Velasco-Vázquez & Verónica Alberto-Barroso , 2023. "The genomic history of the indigenous people of the Canary Islands," Nature Communications, Nature, vol. 14(1), pages 1-11, December.
- Jiacheng Miao & Hanmin Guo & Gefei Song & Zijie Zhao & Lin Hou & Qiongshi Lu, 2023. "Quantifying portable genetic effects and improving cross-ancestry genetic prediction with GWAS summary statistics," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
- Shaan Khurshid & Julieta Lazarte & James P. Pirruccello & Lu-Chen Weng & Seung Hoan Choi & Amelia W. Hall & Xin Wang & Samuel F. Friedman & Victor Nauffal & Kiran J. Biddinger & Krishna G. Aragam & Pu, 2023. "Clinical and genetic associations of deep learning-derived cardiac magnetic resonance-based left ventricular mass," Nature Communications, Nature, vol. 14(1), pages 1-11, December.
- Michael G. Levin & Noah L. Tsao & Pankhuri Singhal & Chang Liu & Ha My T. Vy & Ishan Paranjpe & Joshua D. Backman & Tiffany R. Bellomo & William P. Bone & Kiran J. Biddinger & Qin Hui & Ozan Dikilitas, 2022. "Genome-wide association and multi-trait analyses characterize the common genetic architecture of heart failure," Nature Communications, Nature, vol. 13(1), pages 1-15, December.
- Xinruo Zhang & Jennifer A. Brody & Mariaelisa Graff & Heather M. Highland & Nathalie Chami & Hanfei Xu & Zhe Wang & Kendra R. Ferrier & Geetha Chittoor & Navya Shilpa Josyula & Mariah Meyer & Shreyash, 2025. "Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele," Nature Communications, Nature, vol. 16(1), pages 1-15, December.
- Surina Singh & Ananyo Choudhury & Scott Hazelhurst & Nigel J. Crowther & Palwendé R. Boua & Hermann Sorgho & Godfred Agongo & Engelbert A. Nonterah & Lisa K. Micklesfield & Shane A. Norris & Isaac Kis, 2023. "Genome-wide association study meta-analysis of blood pressure traits and hypertension in sub-Saharan African populations: an AWI-Gen study," Nature Communications, Nature, vol. 14(1), pages 1-14, December.
- Yong Liu & Rajan Pandey & Qiongzi Qiu & Pengyuan Liu & Hong Xue & Jingli Wang & Bhavika Therani & Rong Ying & Kristie Usa & Michael Grzybowski & Chun Yang & Manoj K. Mishra & Andrew S. Greene & Allen , 2025. "Chromatin interaction maps of human arterioles reveal mechanisms for the genetic regulation of blood pressure," Nature Communications, Nature, vol. 16(1), pages 1-16, December.
- Kimon Divaris & Gary D. Slade & Andrea G. Ferreira Zandona & John S. Preisser & Jeannie Ginnis & Miguel A. Simancas-Pallares & Cary S. Agler & Poojan Shrestha & Deepti S. Karhade & Apoena de Aguiar Ri, 2020. "Cohort Profile: ZOE 2.0—A Community-Based Genetic Epidemiologic Study of Early Childhood Oral Health," IJERPH, MDPI, vol. 17(21), pages 1-16, November.
- Alesha A. Hatton & Fei-Fei Cheng & Tian Lin & Ren-Juan Shen & Jie Chen & Zhili Zheng & Jia Qu & Fan Lyu & Sarah E. Harris & Simon R. Cox & Zi-Bing Jin & Nicholas G. Martin & Dongsheng Fan & Grant W. M, 2024. "Genetic control of DNA methylation is largely shared across European and East Asian populations," Nature Communications, Nature, vol. 15(1), pages 1-12, December.