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Learning At The Boundaries In An “Open Regional Innovation System”: A Focus On Firms’ Innovation Strategies In The Emilia Romagna Life Science Industry

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  • fiorenza belussi

    (University of Padua)

  • silvia rita sedita

    (University of Padua)

  • alessia sammarra

    (University of Padua)

Abstract

The paper investigates the existence of an Open Regional Innovation System (ORIS model). This model is characterised by the firms’ adoption of an open innovation strategy, which overcomes not only the boundaries of the firms but also the boundaries of the region. Using data collected in a sample of life science firms, our research provides the evidence that the Emilia Romagna RIS has evolved towards an ORIS model, where firms’ innovation search strategy, despite being still embedded in local nets (involving several regional public research organisations - PROs), is open to external-to-the-region research networks and knowledge sources. It also shows that innovation openness influences significantly the firms’ innovative performance.

Suggested Citation

  • fiorenza belussi & silvia rita sedita & alessia sammarra, 2010. "Learning At The Boundaries In An “Open Regional Innovation System”: A Focus On Firms’ Innovation Strategies In The Emilia Romagna Life Science Industry," "Marco Fanno" Working Papers 0113, Dipartimento di Scienze Economiche "Marco Fanno".
  • Handle: RePEc:pad:wpaper:0113
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    1. Bruce Kogut & Udo Zander, 1992. "Knowledge of the Firm, Combinative Capabilities, and the Replication of Technology," Organization Science, INFORMS, vol. 3(3), pages 383-397, August.
    2. Joel A. C. Baum & Tony Calabrese & Brian S. Silverman, 2000. "Don't go it alone: alliance network composition and startups' performance in Canadian biotechnology," Strategic Management Journal, Wiley Blackwell, vol. 21(3), pages 267-294, March.
    3. Antonelli,Cristiano, 2013. "The economics of technological congruence," Department of Economics and Statistics Cognetti de Martiis LEI & BRICK - Laboratory of Economics of Innovation "Franco Momigliano", Bureau of Research in Innovation, Complexity and Knowledge, Collegio 201304, University of Turin.
    4. Adam B. Jaffe & Manuel Trajtenberg & Rebecca Henderson, 1993. "Geographic Localization of Knowledge Spillovers as Evidenced by Patent Citations," The Quarterly Journal of Economics, Oxford University Press, vol. 108(3), pages 577-598.
    5. Cooke, Philip & Gomez Uranga, Mikel & Etxebarria, Goio, 1997. "Regional innovation systems: Institutional and organisational dimensions," Research Policy, Elsevier, vol. 26(4-5), pages 475-491, December.
    6. Fiorenza Belussi & Luciano Pilotti & Silvia Rita Sedita, 2006. "Learning at the boundaries for industrial districts between exploitation of local resources and exploration of global knowledge flows," "Marco Fanno" Working Papers 0033, Dipartimento di Scienze Economiche "Marco Fanno".
    7. Elisa Giuliani, 2007. "The selective nature of knowledge networks in clusters: evidence from the wine industry," Journal of Economic Geography, Oxford University Press, vol. 7(2), pages 139-168, March.
    8. Lars Coenen & Jerker Moodysson & Bjørn T. Asheim, 2004. "Nodes, networks and proximities: on the knowledge dynamics of the Medicon Valley biotech cluster," European Planning Studies, Taylor & Francis Journals, vol. 12(7), pages 1003-1018, June.
    9. M. S. Gertler & Y. M. Levitte, 2005. "Local Nodes in Global Networks: The Geography of Knowledge Flows in Biotechnology Innovation," Industry and Innovation, Taylor & Francis Journals, vol. 12(4), pages 487-507.
    10. Arora, Ashish & Gambardella, Alfonso, 1994. "The changing technology of technological change: general and abstract knowledge and the division of innovative labour," Research Policy, Elsevier, vol. 23(5), pages 523-532, September.
    11. repec:adr:anecst:y:1998:i:49-50:p:12 is not listed on IDEAS
    12. Hausman, Jerry & Hall, Bronwyn H & Griliches, Zvi, 1984. "Econometric Models for Count Data with an Application to the Patents-R&D Relationship," Econometrica, Econometric Society, vol. 52(4), pages 909-938, July.
    13. John Bound & Clint Cummins & Zvi Griliches & Bronwyn H. Hall & Adam B. Jaffe, 1984. "Who Does R&D and Who Patents?," NBER Chapters, in: R&D, Patents, and Productivity, pages 21-54, National Bureau of Economic Research, Inc.
    14. Maskell, Peter & Malmberg, Anders, 1999. "Localised Learning and Industrial Competitiveness," Cambridge Journal of Economics, Oxford University Press, vol. 23(2), pages 167-185, March.
    15. Anders Malmberg & Peter Maskell, 2006. "Localized Learning Revisited," Growth and Change, Wiley Blackwell, vol. 37(1), pages 1-18, March.
    16. Cohen, Wesley M & Levinthal, Daniel A, 1989. "Innovation and Learning: The Two Faces of R&D," Economic Journal, Royal Economic Society, vol. 99(397), pages 569-596, September.
    17. Crepon, Bruno & Duguet, Emmanuel, 1997. "Research and development, competition and innovation pseudo-maximum likelihood and simulated maximum likelihood methods applied to count data models with heterogeneity," Journal of Econometrics, Elsevier, vol. 79(2), pages 355-378, August.
    18. Carlsson, Bo, 2006. "Internationalization of innovation systems: A survey of the literature," Research Policy, Elsevier, vol. 35(1), pages 56-67, February.
    19. Ron Boschma & Anne L. J. ter Wal, 2007. "Knowledge Networks and Innovative Performance in an Industrial District: The Case of a Footwear District in the South of Italy," Industry and Innovation, Taylor & Francis Journals, vol. 14(2), pages 177-199.
    20. Cristina Boari & Andrea Lipparini, 1999. "Networks within Industrial Districts: Organising Knowledge Creation and Transfer by Means of Moderate Hierarchies," Journal of Management & Governance, Springer;Accademia Italiana di Economia Aziendale (AIDEA), vol. 3(4), pages 339-360, December.
    21. Brusoni, Stefano & Prencipe, Andrea, 2001. "Unpacking the Black Box of Modularity: Technologies, Products and Organizations," Industrial and Corporate Change, Oxford University Press and the Associazione ICC, vol. 10(1), pages 179-205, March.
    22. McKelvey, Maureen & Alm, Hakan & Riccaboni, Massimo, 2003. "Does co-location matter for formal knowledge collaboration in the Swedish biotechnology-pharmaceutical sector?," Research Policy, Elsevier, vol. 32(3), pages 483-501, March.
    23. Philip Cooke, 2001. "New Economy Innovation Systems: Biotechnology In Europe And The Usa," Industry and Innovation, Taylor & Francis Journals, vol. 8(3), pages 267-289.
    24. Gianni Lorenzoni & Andrea Lipparini, 1999. "The leveraging of interfirm relationships as a distinctive organizational capability: a longitudinal study," Strategic Management Journal, Wiley Blackwell, vol. 20(4), pages 317-338, April.
    25. Malerba, Franco, 2002. "Sectoral systems of innovation and production," Research Policy, Elsevier, vol. 31(2), pages 247-264, February.
    26. Hall, Bronwyn H & Griliches, Zvi & Hausman, Jerry A, 1986. "Patents and R and D: Is There a Lag?," International Economic Review, Department of Economics, University of Pennsylvania and Osaka University Institute of Social and Economic Research Association, vol. 27(2), pages 265-283, June.
    27. Fiorenza Belussi & Silvia Rita Sedita, 2008. "Life Cycle vs. Multiple Path Dependency in Industrial Districts," European Planning Studies, Taylor & Francis Journals, vol. 17(4), pages 505-528, November.
    28. Etzkowitz, Henry, 1998. "The norms of entrepreneurial science: cognitive effects of the new university-industry linkages," Research Policy, Elsevier, vol. 27(8), pages 823-833, December.
    29. Niosi, Jorge, 2003. "Alliances are not enough explaining rapid growth in biotechnology firms," Research Policy, Elsevier, vol. 32(5), pages 737-750, May.
    30. Georg Licht & Konrad Zoz, 1998. "Patents and R&D, An Econometric Investigation Using Applications for German, European and US Patents by German Companies," Annals of Economics and Statistics, GENES, issue 49-50, pages 329-360.
    31. Baba, Yasunori & Shichijo, Naohiro & Sedita, Silvia Rita, 2009. "How do collaborations with universities affect firms' innovative performance? The role of "Pasteur scientists" in the advanced materials field," Research Policy, Elsevier, vol. 38(5), pages 756-764, June.
    32. Hartmut Hirsch-Kreinsen & David Jacobson (ed.), 2008. "Innovation in Low-Tech Firms and Industries," Books, Edward Elgar Publishing, number 13088.
    33. Laursen, Keld & Salter, Ammon, 2004. "Searching high and low: what types of firms use universities as a source of innovation?," Research Policy, Elsevier, vol. 33(8), pages 1201-1215, October.
    34. Simona Iammarino, 2005. "An evolutionary integrated view of Regional Systems of Innovation: Concepts, measures and historical perspectives," European Planning Studies, Taylor & Francis Journals, vol. 13(4), pages 497-519, June.
    35. Audretsch, David B. & Bozeman, Barry & Combs, Kathryn L. & Feldman, Maryann & Link, Albert N. & Siegel, Donald S. & Stephan, Paula, 2002. "The Economics of Science and Technology," The Journal of Technology Transfer, Springer, vol. 27(2), pages 155-203, April.
    36. Foss, Nicolai & Mahnke, Volker (ed.), 2000. "Competence, Governance, and Entrepreneurship: Advances in Economic Strategy Research," OUP Catalogue, Oxford University Press, number 9780198297178.
    37. David J. Teece & Gary Pisano & Amy Shuen, 1997. "Dynamic capabilities and strategic management," Strategic Management Journal, Wiley Blackwell, vol. 18(7), pages 509-533, August.
    38. Maskell, Peter, 2001. "Towards a Knowledge-Based Theory of the Geographical Cluster," Industrial and Corporate Change, Oxford University Press and the Associazione ICC, vol. 10(4), pages 921-943, December.
    39. Partha Dasgupta & Paul A. David, 1987. "Information Disclosure and the Economics of Science and Technology," Palgrave Macmillan Books, in: George R. Feiwel (ed.), Arrow and the Ascent of Modern Economic Theory, chapter 16, pages 519-542, Palgrave Macmillan.
    40. Gerald Silverberg & Luc Soete (ed.), 1994. "The Economics Of Growth And Technical Change," Books, Edward Elgar Publishing, number 408.
    41. Joan Penner‐Hahn & J. Myles Shaver, 2005. "Does international research and development increase patent output? An analysis of Japanese pharmaceutical firms," Strategic Management Journal, Wiley Blackwell, vol. 26(2), pages 121-140, February.
    42. Richardson, G B, 1972. "The Organisation of Industry," Economic Journal, Royal Economic Society, vol. 82(327), pages 883-896, September.
    43. Lipparini, Andrea & Sobrero, Maurizio, 1994. "The glue and the pieces: Entrepreneurship and innovation in small-firm networks," Journal of Business Venturing, Elsevier, vol. 9(2), pages 125-140, March.
    44. Todtling, Franz & Trippl, Michaela, 2005. "One size fits all?: Towards a differentiated regional innovation policy approach," Research Policy, Elsevier, vol. 34(8), pages 1203-1219, October.
    45. Jason Owen-Smith & Walter W. Powell, 2004. "Knowledge Networks as Channels and Conduits: The Effects of Spillovers in the Boston Biotechnology Community," Organization Science, INFORMS, vol. 15(1), pages 5-21, February.
    46. Michael Hobday & Andrew Davies & Andrea Prencipe, 2005. "Systems integration: a core capability of the modern corporation," Industrial and Corporate Change, Oxford University Press and the Associazione ICC, vol. 14(6), pages 1109-1143, December.
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    More about this item

    Keywords

    life science sector; learning at the boundaries; Regional Innovation Systems; networks; open innovation model;
    All these keywords.

    JEL classification:

    • L7 - Industrial Organization - - Industry Studies: Primary Products and Construction
    • O31 - Economic Development, Innovation, Technological Change, and Growth - - Innovation; Research and Development; Technological Change; Intellectual Property Rights - - - Innovation and Invention: Processes and Incentives

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