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The Opioid Crisis, Health, Healthcare, and Crime: A Review Of Quasi-Experimental Economic Studies

Author

Listed:
  • Johanna Catherine Maclean
  • Justine Mallatt
  • Christopher J. Ruhm
  • Kosali I. Simon

Abstract

Opioid use is one of the most substantial and long-lasting public health crises faced by the United States. This crisis, which began by the mid-1990s and continues through the time of writing, causes 136 fatal opioid overdoses each day and costs the U.S. at least $596 billion each year. These numbers, while incredibly large, likely do not capture the full toll of the crisis on American society. In this study, we review quasi-experimental studies that examine the relationship between opioids and health and healthcare, and crime outcomes in the U.S. We focus on the U.S., a country particularly hard hit by the crisis which has adopted a broad array of policies aimed at curbing it. Our findings align with the general perception that the opioid crisis has negatively impacted a range of health outcomes and increased healthcare costs, with limited evidence that opioids (which are designed to reduce chronic pain) have enhanced work capacity or other metrics that might capture intended benefits from appropriate use of these medications. While opioids have worsened many health outcomes, the healthcare system played a role in the emergence of the epidemic and its continuation. Further, studies suggest that opioids increase crime, although the link is not as strong as has been observed in previous drug epidemics; this finding is consistent with the pharmacological difference between opioids and stimulant substances (e.g., cocaine) that dominated earlier drug epidemic periods characterized by higher levels of crime. Through the provision of treatment to address underlying addiction and the development of strategies to effectively curtail access to opioids, the healthcare system potentially has an important role in attempts to end the crisis.

Suggested Citation

  • Johanna Catherine Maclean & Justine Mallatt & Christopher J. Ruhm & Kosali I. Simon, 2022. "The Opioid Crisis, Health, Healthcare, and Crime: A Review Of Quasi-Experimental Economic Studies," NBER Working Papers 29983, National Bureau of Economic Research, Inc.
  • Handle: RePEc:nbr:nberwo:29983
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    Cited by:

    1. Isabel Musse, 2025. "Employment shocks and demand for pain medication: Understanding the channels that drive opioid use," Health Economics, John Wiley & Sons, Ltd., vol. 34(2), pages 316-344, February.
    2. Evan D. Peet & David Powell & Rosalie Liccardo Pacula, 2024. "Using Policy and Innovation to Improve Life-Saving Access to Naloxone," NBER Working Papers 33105, National Bureau of Economic Research, Inc.
    3. Lennon, Conor & Maclean, Johanna Catherine & Teltser, Keith, 2025. "Ridesharing and substance use disorder treatment," Journal of Health Economics, Elsevier, vol. 99(C).
    4. Denis Agniel & Jonathan H. Cantor & Johanna Catherine Maclean & Kosali I. Simon & Erin Taylor, 2023. "Insurance Coverage and Provision of Opioid Treatment: Evidence from Medicare," NBER Working Papers 31884, National Bureau of Economic Research, Inc.
    5. Dhaval Dave & Bilge Erten & David Hummel & Pinar Keskin & Shuo Zhang, 2025. "Fighting abuse with prescription tracking: mandatory drug monitoring and intimate partner violence," Journal of Population Economics, Springer;European Society for Population Economics, vol. 38(3), pages 1-27, September.
    6. Beheshti, David & Neller, Seth, 2025. "How does opioid prevalence affect surgery decisions?," Economics Letters, Elsevier, vol. 252(C).
    7. Zai, Xianhua, 2024. "Beyond the brink: Unraveling the opioid crisis and its profound impacts," Economics & Human Biology, Elsevier, vol. 53(C).
    8. Conor Lennon & Johanna Catherine Maclean & Keith F. Teltser, 2024. "Ridesharing and Substance Use Disorder Treatment," NBER Working Papers 33077, National Bureau of Economic Research, Inc.
    9. Dalkhjav, Bayarmaa & Rubini, Loris, 2025. "Hidden information as a source of misallocation: An application to the opioid crisis," Journal of Economic Dynamics and Control, Elsevier, vol. 174(C).

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    JEL classification:

    • I1 - Health, Education, and Welfare - - Health

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