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Sub-Saharan Africa and hepatitis C: challenges and insights regarding the implementation of innovative diagnostics
[Afrique sub-saharienne et hépatite C : défis et perspectives de la mise en œuvre opérationnelle d’outils diagnostiques innovants]


  • Léa Duchesne

    () (iPLESP - Institut Pierre Louis d'Epidémiologie et de Santé Publique - UPMC - Université Pierre et Marie Curie - Paris 6 - INSERM - Institut National de la Santé et de la Recherche Médicale)

  • Victor Duchesne

    () (CEPN - Centre d'Economie de l'Université Paris Nord - CNRS - Centre National de la Recherche Scientifique - USPC - Université Sorbonne Paris Cité - UP13 - Université Paris 13)


With the advent of novel treatments with a cure rate higher than 90%, the elimination of chronic hepatitis C has become achievable. In developing countries, the chronic lack of diagnostic facilities represents a barrier to their spread. The development of a viremic test suitable to decentralized settings appears to be a crucial point of the fight against hepatitis C. Many innovations, based on the principle of frugal innovations, could enable the creation of such a test. Despite their potential, only a small number of these technologies have been made commercially available. The inherent difficulties of the innovation process in developing countries, as well as the lack of collaboration between the different research fields involved during the design phase of the prototypes (manufacturing, integration of feedbacks) and the marketing phase (regulation, distribution, sustainability), reinforce the difficulty of implementing innovative diagnostics.

Suggested Citation

  • Léa Duchesne & Victor Duchesne, 2018. "Sub-Saharan Africa and hepatitis C: challenges and insights regarding the implementation of innovative diagnostics
    [Afrique sub-saharienne et hépatite C : défis et perspectives de la mise en œuvre
    ," Post-Print hal-02017149, HAL.
  • Handle: RePEc:hal:journl:hal-02017149
    DOI: 10.3917/jgem.185.0315.
    Note: View the original document on HAL open archive server:

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