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Two-stage public-private partnership proposal for R&D on neglected diseases


  • Brigitte Granville
  • Eshref Trushin


We propose a 2-stage procurement model of public-private partnership to provide better incentives for R&D on neglected diseases. The model combines advance market commitment, subsidized clinical trials, and rewards based on therapeutical contributions of new drugs through a prize screening mechanism. The model is primarily intended to facilitate small firms’ R&D by providing cash flow, rewarding quality of new drugs, and sharing risks and costs of new drugs development, while limiting moral hazards. The model’s advantages include reduction of overpayments, better disclosure of information, provision of production licences, and direct targeting of better quality drugs.

Suggested Citation

  • Brigitte Granville & Eshref Trushin, 2010. "Two-stage public-private partnership proposal for R&D on neglected diseases," Working Papers 36, Queen Mary, University of London, School of Business and Management, Centre for Globalisation Research.
  • Handle: RePEc:cgs:wpaper:36

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    Cited by:

    1. Jena Anupam B. & Mechoulan Stéphane & Philipson Tomas J., 2013. "Should Global Health be Tailored Toward the Rich? Altruism and Efficient R&D for Neglected Diseases," Forum for Health Economics & Policy, De Gruyter, vol. 16(1), pages 1-36, March.

    More about this item


    neglected diseases; prize screening; pharmaceutical R&D;

    JEL classification:

    • I12 - Health, Education, and Welfare - - Health - - - Health Behavior
    • I18 - Health, Education, and Welfare - - Health - - - Government Policy; Regulation; Public Health
    • D82 - Microeconomics - - Information, Knowledge, and Uncertainty - - - Asymmetric and Private Information; Mechanism Design
    • H41 - Public Economics - - Publicly Provided Goods - - - Public Goods

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