IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0285955.html
   My bibliography  Save this article

Is there an association between periodontal disease and root caries? A systematic review and meta-analysis

Author

Listed:
  • Rayssa Maitê Farias Nazário
  • Deborah Ribeiro Frazão
  • Beatriz Rodrigues Risuenho Peinado
  • Maria Karolina Martins Ferreira
  • Railson de Oliveira Ferreira
  • Marcela Baraúna Magno
  • Nathalia Carolina Fernandes Fagundes
  • Maria Tereza Campos Vidigal
  • Luiz Renato Paranhos
  • Lucianne Cople Maia
  • Rafael Rodrigues Lima

Abstract

Some periodontal diseases can be associated with cariogenic bacterial growth due to various oral health imbalances. This fact may be linked to a greater development of root caries. Thus, this systematic review analyzed the evidence on the association between periodontal disease and root caries. An electronic search was performed in five databases (Cochrane Library, LILACS, MedLine via PubMed, Scopus, and Web of Science) and two additional sources (Google Scholar and Open Grey) to partially capture the grey literature. The PECO strategy was used to identify prospective or retrospective observational studies assessing root caries in patients with periodontal disease without language or year publication restrictions. Two reviewers extracted data and evaluated the individual risk of bias in the eligible studies. Random effects meta-analyses were performed to calculate the Odds Ratio (OR). The risk of bias was assessed by the NIH tool, and the certainty of evidence was classified according to the GRADE tool. There were 1,725 studies retrieved, of which four met the eligibility criteria. All of them were evaluated for the control statements for possible confounders, bias consideration, and confounding factors because they had multivariate analysis. Adults with periodontal disease had a greater chance of presenting root caries than adults without, with OR 1.38 [CI 1.25, 1.53]. The certainty of evidence was classified as very low. Within the limits presented in this review, there was an association between periodontal disease and root caries, highlighted in the qualitative synthesis and the meta-analysis results.

Suggested Citation

  • Rayssa Maitê Farias Nazário & Deborah Ribeiro Frazão & Beatriz Rodrigues Risuenho Peinado & Maria Karolina Martins Ferreira & Railson de Oliveira Ferreira & Marcela Baraúna Magno & Nathalia Carolina F, 2023. "Is there an association between periodontal disease and root caries? A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 18(11), pages 1-17, November.
    • Handle: RePEc:plo:pone00:0285955
    DOI: 10.1371/journal.pone.0285955
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0285955
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0285955&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0285955?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Olaf M Dekkers & Jan P Vandenbroucke & Myriam Cevallos & Andrew G Renehan & Douglas G Altman & Matthias Egger, 2019. "COSMOS-E: Guidance on conducting systematic reviews and meta-analyses of observational studies of etiology," PLOS Medicine, Public Library of Science, vol. 16(2), pages 1-24, February.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Pamela Di Giovanni & Giuseppe Di Martino & Piera Scampoli & Fabrizio Cedrone & Francesca Meo & Giuseppe Lucisano & Ferdinando Romano & Tommaso Staniscia, 2020. "Arsenic Exposure and Risk of Urothelial Cancer: Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 17(9), pages 1-11, April.
    2. Davide, Di Fonzo & Alessandra, Fabri & Roberto, Pasetto, 2022. "Distributive justice in environmental health hazards from industrial contamination: A systematic review of national and near-national assessments of social inequalities," Social Science & Medicine, Elsevier, vol. 297(C).
    3. Matthew J Page & Joanne E McKenzie & Patrick M Bossuyt & Isabelle Boutron & Tammy C Hoffmann & Cynthia D Mulrow & Larissa Shamseer & Jennifer M Tetzlaff & Elie A Akl & Sue E Brennan & Roger Chou & Jul, 2021. "The PRISMA 2020 statement: An updated guideline for reporting systematic reviews," PLOS Medicine, Public Library of Science, vol. 18(3), pages 1-15, March.
    4. Samuel Ofosu-Appiah & Patience Ama Nyantakyiwaa Boahen & Albert Tchey Agbenyegah, 2025. "Socio-ecological barriers to youth entrepreneurship in sub-Saharan Africa: a systematic review of empirical evidence," Journal of Innovation and Entrepreneurship, Springer, vol. 14(1), pages 1-21, December.
    5. François A. Carrillat & Carolin Plewa & Ljubomir Pupovac & Chloé Vanasse & Taylor Willmott & Renaud Legoux & Ekaterina Napolova, 2025. "Can Consumers’ Altruistic Inferences Solve the CSR Initiative Puzzle? A Meta-analytic Investigation," Journal of Business Ethics, Springer, vol. 196(3), pages 639-658, January.
    6. Miranda e Paulo, Djessyca & Navarro de Oliveira, Murilo & de Andrade Vieira, Walbert & Flores-Mir, Carlos & Pithon, Matheus Melo & Bittencourt, Marcos Alan Vieira & Paranhos, Luiz Renato, 2022. "Impact of malocclusion on bullying in school children and adolescents: A systematic review and meta-analysis," Children and Youth Services Review, Elsevier, vol. 142(C).
    7. Roberto Cazzolla Gatti, 2021. "Why We Will Continue to Lose Our Battle with Cancers If We Do Not Stop Their Triggers from Environmental Pollution," IJERPH, MDPI, vol. 18(11), pages 1-19, June.
    8. Yara Shoman & Valentin Rousson & Renzo Bianchi & Irina Guseva Canu, 2022. "Holistic Assessment of Factors Associated with Exhaustion, the Main Symptom of Burnout: A Meta-Analysis of Longitudinal Studies," IJERPH, MDPI, vol. 19(20), pages 1-21, October.
    9. Aina Gabarrell-Pascuet & Helena García-Mieres & Iago Giné-Vázquez & Maria Victoria Moneta & Ai Koyanagi & Josep Maria Haro & Joan Domènech-Abella, 2023. "The Association of Social Support and Loneliness with Symptoms of Depression, Anxiety, and Posttraumatic Stress during the COVID-19 Pandemic: A Meta-Analysis," IJERPH, MDPI, vol. 20(4), pages 1-25, February.
    10. Nikolaos Petroulakis & Mats-Olof Mattsson & Panos Chatziadam & Myrtill Simko & Andreas Gavrielides & Andrianos M. Yiorkas & Olga Zeni & Maria Rosaria Scarfi & Eduardo Soudah & Ruben Otin & Fulvio Sche, 2023. "NextGEM: Next-Generation Integrated Sensing and Analytical System for Monitoring and Assessing Radiofrequency Electromagnetic Field Exposure and Health," IJERPH, MDPI, vol. 20(12), pages 1-18, June.
    11. Nicholas John Dean & Christopher Pastras & Daniel Brown & Aaron Camp, 2019. "Are viral-infections associated with Ménière’s Disease? A systematic review and meta-analysis of molecular-markers of viral-infection in case-controlled observational studies of MD," PLOS ONE, Public Library of Science, vol. 14(11), pages 1-23, November.
    12. Rafael del-Pino-Casado & Emilia Priego-Cubero & Catalina López-Martínez & Vasiliki Orgeta, 2021. "Subjective caregiver burden and anxiety in informal caregivers: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 16(3), pages 1-20, March.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0285955. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.