IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0281665.html
   My bibliography  Save this article

Health professionals’ perceptions on local production and bioequivalence study of generic medicines: A cross-sectional survey of physicians and pharmacy professionals in Addis Ababa, Ethiopia

Author

Listed:
  • Muluken Nigatu Selam
  • Abrham Temesgen Mengstu
  • Atalay Mulu Fentie
  • Gebremedhin Beedemariam Gebretekle
  • Eskinder Eshetu Ali
  • Anteneh Belete

Abstract

Local production of generic medicines in developing countries has a critical role to meet public health needs by ensuring the availability of essential medicines and providing patients’ relief from the burden of unaffordable medical bills. Compliance with bioequivalence (BE) requirements increase the quality and competitiveness of generic drugs regardless of the source. In this regard, a regional BE center has been established in Addis Ababa, Ethiopia to serve the needs of Ethiopia and neighbouring countries. The present study aimed to assess the knowledge and perceptions of health professionals working in Addis Ababa regarding local production and BE studies of generic medicines. A cross-sectional survey was employed and physician participants working at public hospitals and pharmacists from various practice settings were selected using convenient sampling technique. Data was collected using self-administered structured questionnaire. Descriptive statistics was used to summarize the data and multinomial logistic regression analyses was used to assess predictors of health professionals’ perception towards the source of drugs. Statistically significant association was declared at p-value

Suggested Citation

  • Muluken Nigatu Selam & Abrham Temesgen Mengstu & Atalay Mulu Fentie & Gebremedhin Beedemariam Gebretekle & Eskinder Eshetu Ali & Anteneh Belete, 2023. "Health professionals’ perceptions on local production and bioequivalence study of generic medicines: A cross-sectional survey of physicians and pharmacy professionals in Addis Ababa, Ethiopia," PLOS ONE, Public Library of Science, vol. 18(3), pages 1-14, March.
    • Handle: RePEc:plo:pone00:0281665
    DOI: 10.1371/journal.pone.0281665
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0281665
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0281665&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0281665?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. repec:plo:pone00:0218617 is not listed on IDEAS
    2. Chong, Chee Ping & Hassali, Mohamed Azmi & Bahari, Mohd Baidi & Shafie, Asrul Akmal, 2010. "Evaluating community pharmacists' perceptions of future generic substitution policy implementation: A national survey from Malaysia," Health Policy, Elsevier, vol. 94(1), pages 68-75, January.
    3. Chua, Gin Nie & Hassali, Mohamed Azmi & Shafie, Asrul Akmal & Awaisu, Ahmed, 2010. "A survey exploring knowledge and perceptions of general practitioners towards the use of generic medicines in the northern state of Malaysia," Health Policy, Elsevier, vol. 95(2-3), pages 229-235, May.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Alkhuzaee, Fahad S. & Almalki, Hamdan M. & Attar, Ammar Y. & Althubiani, Shoeab I. & Almuallim, Wassam Ali & Cheema, Ejaz & Hadi, Muhammad Abdul, 2016. "Evaluating community pharmacists’ perspectives and practices concerning generic medicines substitution in Saudi Arabia: A cross-sectional study," Health Policy, Elsevier, vol. 120(12), pages 1412-1419.
    2. Hassali, Mohamed Azmi & Wong, Zhi Yen & Alrasheedy, Alian A. & Saleem, Fahad & Mohamad Yahaya, Abdul Haniff & Aljadhey, Hisham, 2014. "Perspectives of physicians practicing in low and middle income countries towards generic medicines: A narrative review," Health Policy, Elsevier, vol. 117(3), pages 297-310.
    3. Ammas Siraj Mohammed & Nigist Alemayehu Woldekidan & Fuad Adem Mohammed, 2020. "Knowledge, attitude, and practice of pharmacy professionals on generic medicines in Eastern Ethiopia: A cross-sectional study," PLOS ONE, Public Library of Science, vol. 15(7), pages 1-12, July.
    4. Mondelo-García, Cristina & Mendoza, Elvia & Movilla-Fernández, María-Jesús & Coronado, Carmen, 2018. "Perceptions of pharmacists and physicians on generic substitution in a financial crisis context in Northwestern Spain: A qualitative study," Health Policy, Elsevier, vol. 122(12), pages 1316-1325.
    5. Fabiano, Valentina & Mameli, Chiara & Cattaneo, Dario & Delle Fave, Antonella & Preziosa, Alessandra & Mele, Giuseppe & Clementi, Emilio & Zuccotti, Gian Vincenzo, 2012. "Perceptions and patterns of use of generic drugs among Italian Family Pediatricians: First round results of a web survey," Health Policy, Elsevier, vol. 104(3), pages 247-252.
    6. Dunne, Suzanne & Shannon, Bill & Hannigan, Ailish & Dunne, Colum & Cullen, Walter, 2014. "Physician and pharmacist perceptions of generic medicines: What they think and how they differ," Health Policy, Elsevier, vol. 116(2), pages 214-223.
    7. Kobayashi, Eriko & Karigome, Hiroshi & Sakurada, Tomoya & Satoh, Nobunori & Ueda, Shiro, 2011. "Patients' attitudes towards generic drug substitution in Japan," Health Policy, Elsevier, vol. 99(1), pages 60-65, January.
    8. Else-Lydia Toverud & Katrin Hartmann & Helle Håkonsen, 2015. "A Systematic Review of Physicians’ and Pharmacists’ Perspectives on Generic Drug Use: What are the Global Challenges?," Applied Health Economics and Health Policy, Springer, vol. 13(1), pages 35-45, August.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0281665. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.