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Mood and behavioral problems are important predictors of quality of life of nursing home residents with moderate to severe dementia: A cross-sectional study

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  • Marinda Henskens
  • Ilse M Nauta
  • Susan Vrijkotte
  • Katja T Drost
  • Maarten V Milders
  • Erik J A Scherder

Abstract

Objectives: To examine the predictors associated with quality of life of nursing home residents with dementia, in order to identify which predictors are most important and hold most promise for future intervention studies. Methods/Design: This cross-sectional analysis of data collected in two intervention trials included 143 participants with moderate to severe dementia who resided in 40 psychogeriatric wards in 13 nursing homes. The outcome measure quality of life was assessed with the Qualidem. Predictors examined were demographic factors, cognition, mood, behavioral problems, and comorbid conditions. Results: Linear mixed regression analyses showed that all nine domains of quality of life showed independent (negative) associations with either depression, agitation, apathy, or a combination of these predictors. Agitation, apathy, depression, and the presence of neurological disease explained 50% of the variance in total quality of life. Male gender, psychiatric/mood disorders, and having one or more comorbid conditions was associated with worse social relations, while the presence of comorbid neurological diseases was associated with more social isolation and a worse care relationship. The presence of endocrine/metabolic disorders and pulmonary disorders was associated with less restless tense behavior. Conclusions: Different domains of quality of life showed different associations, confirming the multidimensionality of quality of life in nursing home residents with dementia. Quality of life is independently associated with mood and behavioral problems, comorbid conditions, and gender. This knowledge may help to identify older persons at risk of a lower quality of life, and to offer targeted interventions to improve quality of life. Trial registration: Dutch Trial registration NTR5641

Suggested Citation

  • Marinda Henskens & Ilse M Nauta & Susan Vrijkotte & Katja T Drost & Maarten V Milders & Erik J A Scherder, 2019. "Mood and behavioral problems are important predictors of quality of life of nursing home residents with moderate to severe dementia: A cross-sectional study," PLOS ONE, Public Library of Science, vol. 14(12), pages 1-16, December.
    • Handle: RePEc:plo:pone00:0223704
    DOI: 10.1371/journal.pone.0223704
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    1. Kirsten Avlund & Rikke Lund & Bjørn E. Holstein & Pernille Due & Ritva Sakari-Rantala & Riitta-Liisa Heikkinen, 2004. "The Impact of Structural and Functional Characteristics of Social Relations as Determinants of Functional Decline," The Journals of Gerontology: Series B, The Gerontological Society of America, vol. 59(1), pages 44-51.
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