IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0127731.html
   My bibliography  Save this article

Adverse Outcomes after Major Surgery in Patients with Pressure Ulcer: A Nationwide Population-Based Retrospective Cohort Study

Author

Listed:
  • Chia-Lun Chou
  • Woan-Ruoh Lee
  • Chun-Chieh Yeh
  • Chun-Chuan Shih
  • Ta-Liang Chen
  • Chien-Chang Liao

Abstract

Background: Postoperative adverse outcomes in patients with pressure ulcer are not completely understood. This study evaluated the association between preoperative pressure ulcer and adverse events after major surgeries. Methods: Using reimbursement claims from Taiwan’s National Health Insurance Research Database, we conducted a nationwide retrospective cohort study of 17391 patients with preoperative pressure ulcer receiving major surgery in 2008-2010. With a propensity score matching procedure, 17391 surgical patients without pressure ulcer were selected for comparison. Eight major surgical postoperative complications and 30-day postoperative mortality were evaluated among patients with pressure ulcer of varying severity. Results: Patients with preoperative pressure ulcer had significantly higher risk than controls for postoperative adverse outcomes, including septicemia, pneumonia, stroke, urinary tract infection, and acute renal failure. Surgical patients with pressure ulcer had approximately 1.83-fold risk (95% confidence interval 1.54-2.18) of 30-day postoperative mortality compared with control group. The most significant postoperative mortality was found in those with serious pressure ulcer, such as pressure ulcer with local infection, cellulitis, wound or treatment by change dressing, hospitalized care, debridement or antibiotics. Prolonged hospital or intensive care unit stay and increased medical expenditures were also associated with preoperative pressure ulcer. Conclusion: This nationwide propensity score-matched retrospective cohort study showed increased postoperative complications and mortality in patients with preoperative pressure ulcer. Our findings suggest the urgency of preventing and managing preoperative pressure ulcer by a multidisciplinary medical team for this specific population.

Suggested Citation

  • Chia-Lun Chou & Woan-Ruoh Lee & Chun-Chieh Yeh & Chun-Chuan Shih & Ta-Liang Chen & Chien-Chang Liao, 2015. "Adverse Outcomes after Major Surgery in Patients with Pressure Ulcer: A Nationwide Population-Based Retrospective Cohort Study," PLOS ONE, Public Library of Science, vol. 10(5), pages 1-12, May.
    • Handle: RePEc:plo:pone00:0127731
    DOI: 10.1371/journal.pone.0127731
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127731
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0127731&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0127731?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Peter Libby, 2002. "Inflammation in atherosclerosis," Nature, Nature, vol. 420(6917), pages 868-874, December.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Min Jung Han & Sangjin Ko, 2021. "Comparison of Interface Pressures and Subjective Comfort of Pressure-Relieving Overlays on the Operating Table for Healthy Volunteers," IJERPH, MDPI, vol. 18(5), pages 1-7, March.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Marit Skogstad & Asgeir Mamen & Lars-Kristian Lunde & Bente Ulvestad & Dagfinn Matre & Hans Christian D. Aass & Reidun Øvstebø & Pia Nielsen & Kari N. Samuelsen & Øivind Skare & Per Anton Sirnes, 2019. "Shift Work Including Night Work and Long Working Hours in Industrial Plants Increases the Risk of Atherosclerosis," IJERPH, MDPI, vol. 16(3), pages 1-11, February.
    2. Wen Kong & Xun Niu & Tianshu Zeng & Meixia Lu & Lulu Chen, 2015. "Impact of Treatment with Metformin on Adipocytokines in Patients with Polycystic Ovary Syndrome: A Meta-Analysis," PLOS ONE, Public Library of Science, vol. 10(10), pages 1-20, October.
    3. Nonanzit Pérez-Hernández & Gilberto Vargas-Alarcón & Rosalinda Posadas-Sánchez & Nancy Martínez-Rodríguez & Carlos Alfonso Tovilla-Zárate & Adrián Asael Rodríguez-Cortés & Oscar Pérez-Méndez & Ruben B, 2016. "PHACTR1 Gene Polymorphism Is Associated with Increased Risk of Developing Premature Coronary Artery Disease in Mexican Population," IJERPH, MDPI, vol. 13(8), pages 1-9, August.
    4. Quefeng Li & Sijian Wang & Chiang-Ching Huang & Menggang Yu & Jun Shao, 2014. "Meta-analysis based variable selection for gene expression data," Biometrics, The International Biometric Society, vol. 70(4), pages 872-880, December.
    5. Mouna Achoui & David Appleton & Mahmood Ameen Abdulla & Khalijah Awang & Mustafa Ali Mohd & Mohd Rais Mustafa, 2010. "In Vitro and In Vivo Anti-Inflammatory Activity of 17-O-Acetylacuminolide through the Inhibition of Cytokines, NF-κB Translocation and IKKβ Activity," PLOS ONE, Public Library of Science, vol. 5(12), pages 1-13, December.
    6. Jonas Helgertz & Tommy Bengtsson, 2019. "The Long-Lasting Influenza: The Impact of Fetal Stress During the 1918 Influenza Pandemic on Socioeconomic Attainment and Health in Sweden, 1968–2012," Demography, Springer;Population Association of America (PAA), vol. 56(4), pages 1389-1425, August.
    7. Elżbieta Dembowska & Aleksandra Jaroń & Ewa Gabrysz-Trybek & Joanna Bladowska & Grzegorz Trybek, 2022. "Evaluation of Common Factors of Periodontitis and Cardiovascular Disease in Patients with the Acute Coronary Syndrome," IJERPH, MDPI, vol. 19(13), pages 1-14, July.
    8. Yun Hwan Kim & Min Ki Jeong & Hyuntae Park & Sang Kab Park, 2021. "Effects of Regular Taekwondo Intervention on Health-Related Physical Fitness, Cardiovascular Disease Risk Factors and Epicardial Adipose Tissue in Elderly Women with Hypertension," IJERPH, MDPI, vol. 18(6), pages 1-14, March.
    9. Mengying Wang & Siyue Wang & Xiaowen Wang & Junhui Wu & Yao Wu & Zijing Wang & Jiating Wang & Tao Wu & Yonghua Hu, 2020. "Carotid Intima-Media Thickness, Genetic Risk, and Ischemic Stroke: A Family-Based Study in Rural China," IJERPH, MDPI, vol. 18(1), pages 1-11, December.
    10. repec:plo:pone00:0018800 is not listed on IDEAS
    11. Joshua D. Landvatter & Bert N. Uchino & Timothy W. Smith & Jos A. Bosch, 2022. "Partner’s Perceived Social Support Influences Their Spouse’s Inflammation: An Actor–Partner Analysis," IJERPH, MDPI, vol. 19(2), pages 1-9, January.
    12. repec:plo:pone00:0138290 is not listed on IDEAS
    13. Salvatore Novo & Bonomo Vito & Di Piazza Mariaconcetta & Piero Levantino, 2017. "Metabolic Syndrome: From the Pathophysiology to the Treatment. A Comprehensive Review," International Journal of Sciences, Office ijSciences, vol. 6(08), pages 1-8, August.
    14. Hidalgo, Arturo & Tello, Lourdes, 2023. "A numerical approach to a 2D porous-medium mathematical model: Application to an atherosclerosis problem," Applied Mathematics and Computation, Elsevier, vol. 441(C).
    15. Kanyarat Kanokphichayakrai & Watchara Kaewmahanin & Orathai Tangvarasittichai & Surapon Tangvarasittichai & Watchara Kaewmahanin, 2017. "Cardio-Ankle Vascular Index (CAVI) Measurement of Arterial Stiffness Associated with Cardiovascular Disease Risk Factors in Type 2 Diabetes Patients," Current Research in Diabetes & Obesity Journal, Juniper Publishers Inc., vol. 5(1), pages 1-8, November.
    16. Moritz Kebschull & Manuela Haupt & Søren Jepsen & James Deschner & Georg Nickenig & Nikos Werner, 2013. "Mobilization of Endothelial Progenitors by Recurrent Bacteremias with a Periodontal Pathogen," PLOS ONE, Public Library of Science, vol. 8(1), pages 1-9, January.
    17. Marit Skogstad & Lars-Kristian Lunde & Bente Ulvestad & Hans Christian D. Aass & Thomas Clemm & Asgeir Mamen & Øivind Skare, 2018. "The Effect of a Leisure Time Physical Activity Intervention Delivered via a Workplace: 15-Month Follow-Up Study," IJERPH, MDPI, vol. 15(2), pages 1-13, February.
    18. Gian Paolo Fadini & Shoichi Maruyama & Takenori Ozaki & Akihiko Taguchi & James Meigs & Stefanie Dimmeler & Andreas M Zeiher & Saula de Kreutzenberg & Angelo Avogaro & Georg Nickenig & Caroline Schmid, 2010. "Circulating Progenitor Cell Count for Cardiovascular Risk Stratification: A Pooled Analysis," PLOS ONE, Public Library of Science, vol. 5(7), pages 1-9, July.
    19. Hyunji Kim & Yoon Jeong Cho & Yun A. Kim & Sang Gyu Gwak, 2018. "Association between Colorectal Adenoma and Carotid Atherosclerosis in Korean Adults," IJERPH, MDPI, vol. 15(12), pages 1-8, December.
    20. Raluca Niculescu & Eliza Russu & Emil Marian Arbănași & Réka Kaller & Eliza Mihaela Arbănași & Răzvan Marian Melinte & Cătălin Mircea Coșarcă & Iuliu Gabriel Cocuz & Adrian Horațiu Sabău & Andreea Căt, 2022. "Carotid Plaque Features and Inflammatory Biomarkers as Predictors of Restenosis and Mortality Following Carotid Endarterectomy," IJERPH, MDPI, vol. 19(21), pages 1-14, October.
    21. Vincent Grote & Matthias Frühwirth & Helmut K. Lackner & Nandu Goswami & Markus Köstenberger & Rudolf Likar & Maximilian Moser, 2021. "Cardiorespiratory Interaction and Autonomic Sleep Quality Improve during Sleep in Beds Made from Pinus cembra (Stone Pine) Solid Wood," IJERPH, MDPI, vol. 18(18), pages 1-20, September.
    22. Anne Mette Fisker Hag & Sune Folke Pedersen & Christina Christoffersen & Tina Binderup & Mette Munk Jensen & Jesper Tranekjær Jørgensen & Dorthe Skovgaard & Rasmus Sejersten Ripa & Andreas Kjaer, 2012. "18F-FDG PET Imaging of Murine Atherosclerosis: Association with Gene Expression of Key Molecular Markers," PLOS ONE, Public Library of Science, vol. 7(11), pages 1-9, November.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0127731. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.