IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0114666.html
   My bibliography  Save this article

Albumin versus Other Fluids for Fluid Resuscitation in Patients with Sepsis: A Meta-Analysis

Author

Listed:
  • Libing Jiang
  • Shouyin Jiang
  • Mao Zhang
  • Zhongjun Zheng
  • Yuefeng Ma

Abstract

Background: Early fluid resuscitation is vital to patients with sepsis. However, the choice of fluid has been a hot topic of discussion. The objective of this study was to evaluate whether the use of albumin-containing fluids for resuscitation in patients with sepsis was associated with a decreased mortality rate. Methods: We systematically searched PubMed, EMBASE and Cochrane library for eligible randomized controlled trials (RCTs) up to March 2014. The selection of eligible studies, assessment of methodological quality, and extraction of all relevant data were conducted by two authors independently. Results: In total, 15 RCTs were eligible for analysis. After pooling the data, we found there was no significant effect of albumin-containing fluids on mortality in patients with sepsis of any severity (RR: 0.94, 95% CI: 0.87, 1.02 and RD: –0.01, 95% CI: –0.03, 0.01). The results were robust to subgroup analyses, sensitivity analyses and trial sequential analyses. Conclusion: The present meta-analysis did not demonstrate significant advantage of using albumin-containing fluids for resuscitation in patients with sepsis of any severity. Given the cost-effectiveness of using albumin, crystalloids should be the first choice for fluid resuscitation in septic patients.

Suggested Citation

  • Libing Jiang & Shouyin Jiang & Mao Zhang & Zhongjun Zheng & Yuefeng Ma, 2014. "Albumin versus Other Fluids for Fluid Resuscitation in Patients with Sepsis: A Meta-Analysis," PLOS ONE, Public Library of Science, vol. 9(12), pages 1-21, December.
  • Handle: RePEc:plo:pone00:0114666
    DOI: 10.1371/journal.pone.0114666
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0114666
    Download Restriction: no

    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0114666&type=printable
    Download Restriction: no

    File URL: https://libkey.io/10.1371/journal.pone.0114666?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. David Moher & Alessandro Liberati & Jennifer Tetzlaff & Douglas G Altman & The PRISMA Group, 2009. "Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement," PLOS Medicine, Public Library of Science, vol. 6(7), pages 1-6, July.
    2. Kenneth F Schulz & Douglas G Altman & David Moher & for the CONSORT Group, 2010. "CONSORT 2010 Statement: Updated Guidelines for Reporting Parallel Group Randomised Trials," PLOS Medicine, Public Library of Science, vol. 7(3), pages 1-7, March.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Su Keng Tan & Wai Keung Leung & Alexander Tin Hong Tang & Roger A Zwahlen, 2017. "Effects of mandibular setback with or without maxillary advancement osteotomies on pharyngeal airways: An overview of systematic reviews," PLOS ONE, Public Library of Science, vol. 12(10), pages 1-20, October.
    2. Jovana Kuzmanovic Pficer & Slobodan Dodic & Vojkan Lazic & Goran Trajkovic & Natasa Milic & Biljana Milicic, 2017. "Occlusal stabilization splint for patients with temporomandibular disorders: Meta-analysis of short and long term effects," PLOS ONE, Public Library of Science, vol. 12(2), pages 1-21, February.
    3. Clovis Mariano Faggion Jr & Yun-Chun Wu & Moritz Scheidgen & Yu-Kang Tu, 2015. "Effect of Risk of Bias on the Effect Size of Meta-Analytic Estimates in Randomized Controlled Trials in Periodontology and Implant Dentistry," PLOS ONE, Public Library of Science, vol. 10(9), pages 1-9, September.
    4. Salvador Angosto & Jerónimo García-Fernández & Irena Valantine & Moisés Grimaldi-Puyana, 2020. "The Intention to Use Fitness and Physical Activity Apps: A Systematic Review," Sustainability, MDPI, vol. 12(16), pages 1-25, August.
    5. Mahesh Shumsher Rughooputh & Rui Zeng & Ying Yao, 2015. "Protein Diet Restriction Slows Chronic Kidney Disease Progression in Non-Diabetic and in Type 1 Diabetic Patients, but Not in Type 2 Diabetic Patients: A Meta-Analysis of Randomized Controlled Trials ," PLOS ONE, Public Library of Science, vol. 10(12), pages 1-17, December.
    6. Laith Hussain-Alkhateeb & Tatiana Rivera Ramírez & Axel Kroeger & Ernesto Gozzer & Silvia Runge-Ranzinger, 2021. "Early warning systems (EWSs) for chikungunya, dengue, malaria, yellow fever, and Zika outbreaks: What is the evidence? A scoping review," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 15(9), pages 1-25, September.
    7. Shalin Lee Wan Fei & Khatijah L Abdullah, 2015. "Effect of turning vs. supine position under phototherapy on neonates with hyperbilirubinemia: a systematic review," Journal of Clinical Nursing, John Wiley & Sons, vol. 24(5-6), pages 672-682, March.
    8. Savita Bakhshi & Alison E. While, 2013. "Health Professionals’ Alcohol-Related Professional Practices and the Relationship between Their Personal Alcohol Attitudes and Behavior and Professional Practices: A Systematic Review," IJERPH, MDPI, vol. 11(1), pages 1-31, December.
    9. Finkelstein, Eric A. & Bilger, Marcel & Baid, Drishti, 2019. "Effectiveness and cost-effectiveness of incentives as a tool for prevention of non-communicable diseases: A systematic review," Social Science & Medicine, Elsevier, vol. 232(C), pages 340-350.
    10. João Carlos Belloti & Aldo Okamura & Jordana Scheeren & Flávio Faloppa & Vinícius Ynoe de Moraes, 2019. "A systematic review of the quality of distal radius systematic reviews: Methodology and reporting assessment," PLOS ONE, Public Library of Science, vol. 14(1), pages 1-12, January.
    11. Kevin Rudolf & Lea A. L. Dejonghe & Ingo Froböse & Florian Lammer & Lisa-Marie Rückel & Jessica Tetz & Andrea Schaller, 2019. "Effectiveness Studies in Health Promotion: A Review of the Methodological Quality of Studies Reporting Significant Effects on Physical Activity in Working Age Adults," IJERPH, MDPI, vol. 16(5), pages 1-17, March.
    12. Taweewat Wiangkham & Joan Duda & Sayeed Haque & Mohammad Madi & Alison Rushton, 2015. "The Effectiveness of Conservative Management for Acute Whiplash Associated Disorder (WAD) II: A Systematic Review and Meta-Analysis of Randomised Controlled Trials," PLOS ONE, Public Library of Science, vol. 10(7), pages 1-22, July.
    13. Abigail Stevely & Munyaradzi Dimairo & Susan Todd & Steven A Julious & Jonathan Nicholl & Daniel Hind & Cindy L Cooper, 2015. "An Investigation of the Shortcomings of the CONSORT 2010 Statement for the Reporting of Group Sequential Randomised Controlled Trials: A Methodological Systematic Review," PLOS ONE, Public Library of Science, vol. 10(11), pages 1-20, November.
    14. Mulhall, Peter & Taggart, Laurence & Coates, Vivien & McAloon, Toni & Hassiotis, Angela, 2018. "A systematic review of the methodological and practical challenges of undertaking randomised-controlled trials with cognitive disability populations," Social Science & Medicine, Elsevier, vol. 200(C), pages 114-128.
    15. Harrington, Nancy Grant & Scott, Allison M. & Spencer, Elizabeth A., 2020. "Working toward evidence-based guidelines for cost-of-care conversations between patients and physicians: A systematic review of the literature," Social Science & Medicine, Elsevier, vol. 258(C).
    16. Waleska Reyes-Ferrada & Luis Chirosa-Rios & Angela Rodriguez-Perea & Daniel Jerez-Mayorga & Ignacio Chirosa-Rios, 2021. "Isokinetic Trunk Strength in Acute Low Back Pain Patients Compared to Healthy Subjects: A Systematic Review," IJERPH, MDPI, vol. 18(5), pages 1-13, March.
    17. Faith Donald & Kelley Kilpatrick & Kim Reid & Nancy Carter & Ruth Martin-Misener & Denise Bryant-Lukosius & Patricia Harbman & Sharon Kaasalainen & Deborah A. Marshall & Renee Charbonneau-Smith & Erin, 2014. "A Systematic Review of the Cost-Effectiveness of Nurse Practitioners and Clinical Nurse Specialists: What Is the Quality of the Evidence?," Nursing Research and Practice, Hindawi, vol. 2014, pages 1-28, September.
    18. Daisuke Kato & Yuki Kataoka & Erfen Gustiawan Suwangto & Makoto Kaneko & Hideki Wakabayashi & Daisuke Son & Ichiro Kawachi, 2020. "Reporting Guidelines for Community-Based Participatory Research Did Not Improve the Reporting Quality of Published Studies: A Systematic Review of Studies on Smoking Cessation," IJERPH, MDPI, vol. 17(11), pages 1-9, May.
    19. Kartika Saraswati & Brittany J Maguire & Alistair R D McLean & Sauman Singh-Phulgenda & Roland C Ngu & Paul N Newton & Nicholas P J Day & Philippe J Guérin, 2021. "Systematic review of the scrub typhus treatment landscape: Assessing the feasibility of an individual participant-level data (IPD) platform," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 15(10), pages 1-22, October.
    20. Ana Virgolino & Osvaldo Santos & Joana Costa & Mónica Fialho & Ivo Iavicoli & Tiina Santonen & Hanna Tolonen & Evangelia Samoli & Klea Katsouyanni & Georgios Baltatzis & Flavia Ruggieri & Annalisa Abb, 2021. "Challenges to Evidence Synthesis and Identification of Data Gaps in Human Biomonitoring," IJERPH, MDPI, vol. 18(6), pages 1-11, March.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0114666. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.