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GIANT: A Cytoscape Plugin for Modular Networks

Author

Listed:
  • Fabio Cumbo
  • Paola Paci
  • Daniele Santoni
  • Luisa Di Paola
  • Alessandro Giuliani

Abstract

Network analysis provides deep insight into real complex systems. Revealing the link between topological and functional role of network elements can be crucial to understand the mechanisms underlying the system. Here we propose a Cytoscape plugin (GIANT) to perform network clustering and characterize nodes at the light of a modified Guimerà-Amaral cartography. This approach results into a vivid picture of the a topological/functional relationship at both local and global level. The plugin has been already approved and uploaded on the Cytoscape APP store.

Suggested Citation

  • Fabio Cumbo & Paola Paci & Daniele Santoni & Luisa Di Paola & Alessandro Giuliani, 2014. "GIANT: A Cytoscape Plugin for Modular Networks," PLOS ONE, Public Library of Science, vol. 9(10), pages 1-7, October.
    • Handle: RePEc:plo:pone00:0105001
    DOI: 10.1371/journal.pone.0105001
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    References listed on IDEAS

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    1. Jing-Dong J. Han & Nicolas Bertin & Tong Hao & Debra S. Goldberg & Gabriel F. Berriz & Lan V. Zhang & Denis Dupuy & Albertha J. M. Walhout & Michael E. Cusick & Frederick P. Roth & Marc Vidal, 2004. "Erratum: Evidence for dynamically organized modularity in the yeast protein–protein interaction network," Nature, Nature, vol. 430(6997), pages 380-380, July.
    2. Jing-Dong J. Han & Nicolas Bertin & Tong Hao & Debra S. Goldberg & Gabriel F. Berriz & Lan V. Zhang & Denis Dupuy & Albertha J. M. Walhout & Michael E. Cusick & Frederick P. Roth & Marc Vidal, 2004. "Evidence for dynamically organized modularity in the yeast protein–protein interaction network," Nature, Nature, vol. 430(6995), pages 88-93, July.
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    1. Zoltan Lakner & Anna Kiss & Bela Vizvari & Jozsef Popp, 2021. "Trade Liberalisation and Sustainability: A Case Study of Agro-Food Transport Optimisation," European Research Studies Journal, European Research Studies Journal, vol. 0(1), pages 822-839.

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